#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O07025 uniprotkb:O07025 intact:EBI-957989|uniprotkb:P94822|ensemblbacteria:AAD08462 intact:EBI-957989|uniprotkb:P94822|ensemblbacteria:AAD08462 psi-mi:flii_helpy(display_long)|uniprotkb:fliI(gene name)|psi-mi:fliI(display_short)|uniprotkb:HP_1420(locus name) psi-mi:flii_helpy(display_long)|uniprotkb:fliI(gene name)|psi-mi:fliI(display_short)|uniprotkb:HP_1420(locus name) psi-mi:"MI:0027"(cosedimentation) Lane et al. (2006) imex:IM-14496|pubmed:16260786 taxid:85962(helpy)|taxid:85962(Helicobacter pylori) taxid:85962(helpy)|taxid:85962(Helicobacter pylori) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-958011|imex:IM-14496-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_208211.1|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR020003|interpro:IPR027417|interpro:IPR040627|ensemblbacteria:AAD08462(transcript)|ensemblbacteria:HP_1420(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0030254"(protein secretion by the type III secretion system)|go:"GO:0030257"(type III protein secretion system complex)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_001128709.1|mint:O07025|dip:DIP-3391N refseq:NP_208211.1|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR020003|interpro:IPR027417|interpro:IPR040627|ensemblbacteria:AAD08462(transcript)|ensemblbacteria:HP_1420(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0030254"(protein secretion by the type III secretion system)|go:"GO:0030257"(type III protein secretion system complex)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_001128709.1|mint:O07025|dip:DIP-3391N go:"GO:0051260"(protein homooligomerization) - - figure legend:2, 6B|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/17 2014/10/16 rogid:Wu07gCjjYlkYYC5l0nNDwVtgz6k85962 rogid:Wu07gCjjYlkYYC5l0nNDwVtgz6k85962 intact-crc:D471098BE3404F77|rigid:uERqPM29jF1DsLFLo8sBcnp8MEI false sufficient binding region:19-91 sufficient binding region:19-91 3 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O25120 uniprotkb:O25120 intact:EBI-958087|ensemblbacteria:AAD07421 intact:EBI-958087|ensemblbacteria:AAD07421 psi-mi:o25120_helpy(display_long)|uniprotkb:HP_0353(locus name) psi-mi:o25120_helpy(display_long)|uniprotkb:HP_0353(locus name) psi-mi:"MI:0027"(cosedimentation) Lane et al. (2006) imex:IM-14496|pubmed:16260786 taxid:85962(helpy)|taxid:85962(Helicobacter pylori) taxid:85962(helpy)|taxid:85962(Helicobacter pylori) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-958094|imex:IM-14496-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_207151.1|ensemblbacteria:AAD07421(transcript)|ensemblbacteria:HP_0353(gene)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|interpro:IPR018035|refseq:WP_000056222.1|mint:O25120|dip:DIP-3389N refseq:NP_207151.1|ensemblbacteria:AAD07421(transcript)|ensemblbacteria:HP_0353(gene)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|interpro:IPR018035|refseq:WP_000056222.1|mint:O25120|dip:DIP-3389N go:"GO:0051260"(protein homooligomerization) - - figure legend:2, 6B|comment:FliH can exist as trimers, or more commonly as dimers, under these experimental conditions.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/17 2014/10/16 rogid:fm+JdqLw8CUsLWheaipN3wHJ0pE85962 rogid:fm+JdqLw8CUsLWheaipN3wHJ0pE85962 intact-crc:F5FAA98F001A24A7|rigid:vQxerahj7S9PEiotE7gUYCRWxm4 false sufficient binding region:117-258 sufficient binding region:117-258 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07025 uniprotkb:O25120 intact:EBI-957989|uniprotkb:P94822|ensemblbacteria:AAD08462 intact:EBI-958087|ensemblbacteria:AAD07421 psi-mi:flii_helpy(display_long)|uniprotkb:fliI(gene name)|psi-mi:fliI(display_short)|uniprotkb:HP_1420(locus name) psi-mi:o25120_helpy(display_long)|uniprotkb:HP_0353(locus name) psi-mi:"MI:0027"(cosedimentation) Lane et al. (2006) imex:IM-14496|pubmed:16260786 taxid:85962(helpy)|taxid:85962(Helicobacter pylori) taxid:85962(helpy)|taxid:85962(Helicobacter pylori) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-958839|imex:IM-14496-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_208211.1|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR020003|interpro:IPR027417|interpro:IPR040627|ensemblbacteria:AAD08462(transcript)|ensemblbacteria:HP_1420(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0030254"(protein secretion by the type III secretion system)|go:"GO:0030257"(type III protein secretion system complex)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_001128709.1|mint:O07025|dip:DIP-3391N refseq:NP_207151.1|ensemblbacteria:AAD07421(transcript)|ensemblbacteria:HP_0353(gene)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|interpro:IPR018035|refseq:WP_000056222.1|mint:O25120|dip:DIP-3389N go:"GO:0051259"(protein complex oligomerization) - - figure legend:6, 7|comment:The molecular weight of the complex is estimated at 1.3 x 10EXP6 D.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/17 2014/10/16 rogid:Wu07gCjjYlkYYC5l0nNDwVtgz6k85962 rogid:fm+JdqLw8CUsLWheaipN3wHJ0pE85962 intact-crc:96CEA3C4195436CA|rigid:CLNnlWyq0lL56uAQ+Lv4ddRU4Nw false sufficient binding region:2-91|mutation decreasing interaction:3-3|necessary binding region:2-8 sufficient binding region:117-258 4 3 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O25120 uniprotkb:O07025 intact:EBI-958087|ensemblbacteria:AAD07421 intact:EBI-957989|uniprotkb:P94822|ensemblbacteria:AAD08462 psi-mi:o25120_helpy(display_long)|uniprotkb:HP_0353(locus name) psi-mi:flii_helpy(display_long)|uniprotkb:fliI(gene name)|psi-mi:fliI(display_short)|uniprotkb:HP_1420(locus name) psi-mi:"MI:0096"(pull down) Lane et al. (2006) imex:IM-14496|pubmed:16260786 taxid:85962(helpy)|taxid:85962(Helicobacter pylori) taxid:85962(helpy)|taxid:85962(Helicobacter pylori) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-958122|imex:IM-14496-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_207151.1|ensemblbacteria:AAD07421(transcript)|ensemblbacteria:HP_0353(gene)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|interpro:IPR018035|refseq:WP_000056222.1|mint:O25120|dip:DIP-3389N refseq:NP_208211.1|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR020003|interpro:IPR027417|interpro:IPR040627|ensemblbacteria:AAD08462(transcript)|ensemblbacteria:HP_1420(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0030254"(protein secretion by the type III secretion system)|go:"GO:0030257"(type III protein secretion system complex)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_001128709.1|mint:O07025|dip:DIP-3391N psi-mi:"MI:0469"(intact) - - figure legend:4|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/17 2014/10/16 rogid:fm+JdqLw8CUsLWheaipN3wHJ0pE85962 rogid:Wu07gCjjYlkYYC5l0nNDwVtgz6k85962 intact-crc:C34C2E98E1B1E02B|rigid:CLNnlWyq0lL56uAQ+Lv4ddRU4Nw false sufficient binding region:117-258 sufficient binding region:2-18|glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07025 uniprotkb:O25120 intact:EBI-957989|uniprotkb:P94822|ensemblbacteria:AAD08462 intact:EBI-958087|ensemblbacteria:AAD07421 psi-mi:flii_helpy(display_long)|uniprotkb:fliI(gene name)|psi-mi:fliI(display_short)|uniprotkb:HP_1420(locus name) psi-mi:o25120_helpy(display_long)|uniprotkb:HP_0353(locus name) psi-mi:"MI:0096"(pull down) Lane et al. (2006) imex:IM-14496|pubmed:16260786 taxid:85962(helpy)|taxid:85962(Helicobacter pylori) taxid:85962(helpy)|taxid:85962(Helicobacter pylori) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-958816|imex:IM-14496-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_208211.1|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR020003|interpro:IPR027417|interpro:IPR040627|ensemblbacteria:AAD08462(transcript)|ensemblbacteria:HP_1420(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0030254"(protein secretion by the type III secretion system)|go:"GO:0030257"(type III protein secretion system complex)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_001128709.1|mint:O07025|dip:DIP-3391N refseq:NP_207151.1|ensemblbacteria:AAD07421(transcript)|ensemblbacteria:HP_0353(gene)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|interpro:IPR018035|refseq:WP_000056222.1|mint:O25120|dip:DIP-3389N psi-mi:"MI:0469"(intact) - - figure legend:5|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/17 2014/10/16 rogid:Wu07gCjjYlkYYC5l0nNDwVtgz6k85962 rogid:fm+JdqLw8CUsLWheaipN3wHJ0pE85962 intact-crc:8B1ECF072380F151|rigid:CLNnlWyq0lL56uAQ+Lv4ddRU4Nw false sufficient binding region:2-18|mutation decreasing interaction:3-3|mutation decreasing interaction:6-6|mutation decreasing interaction:10-10|mutation decreasing interaction:6-6|mutation decreasing interaction:9-9 sufficient binding region:117-258|glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)