#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P12977 uniprotkb:P35869 intact:EBI-993115|uniprotkb:Q66540|uniprotkb:P03202|uniprotkb:Q69021|uniprotkb:Q8AZJ8 intact:EBI-80780|uniprotkb:A4D130|ensembl:ENSP00000242057|ensembl:ENSP00000436466|uniprotkb:Q13728|uniprotkb:Q13803|uniprotkb:Q13804 psi-mi:ebna3_ebvb9(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:ahr_human(display_long)|uniprotkb:AHR(gene name)|psi-mi:AHR(display_short)|uniprotkb:BHLHE76(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 76(gene name synonym) psi-mi:"MI:0096"(pull down) Kashuba et al. (2006) imex:IM-14447|pubmed:16257957|mint:MINT-6594475 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-993110|imex:IM-14447-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6VMX|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0044204"(host cell nuclear matrix)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|refseq:YP_401669.1|rcsb pdb:1M05|rcsb pdb:1XR8|rcsb pdb:5WMO interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:5NJ8|reactome:R-HSA-1989781|reactome:R-HSA-211945|reactome:R-HSA-211976|reactome:R-HSA-211981|reactome:R-HSA-8937144|ensembl:ENSG00000106546(gene)|ensembl:ENST00000242057(transcript)|ensembl:ENST00000463496(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001568"(blood vessel development)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002841"(negative regulation of T cell mediated immune response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0005829"(cytosol)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034752"(cytosolic aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|refseq:NP_001612.1|dip:DIP-946N psi-mi:"MI:0469"(intact) - - figure legend:1B|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/08/08 2014/10/16 rogid:0HIls6vxksxriVNTv5M9V6FND8E10377 rogid:7hBqGKPH2nBDWpy9UoQ7+KpY+ic9606 intact-crc:3B934D12941E3539|rigid:kc9vXFVrelLzvLcO2ACd7T+mOKM false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P12977 uniprotkb:P35869 intact:EBI-993115|uniprotkb:Q66540|uniprotkb:P03202|uniprotkb:Q69021|uniprotkb:Q8AZJ8 intact:EBI-80780|uniprotkb:A4D130|ensembl:ENSP00000242057|ensembl:ENSP00000436466|uniprotkb:Q13728|uniprotkb:Q13803|uniprotkb:Q13804 psi-mi:ebna3_ebvb9(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:ahr_human(display_long)|uniprotkb:AHR(gene name)|psi-mi:AHR(display_short)|uniprotkb:BHLHE76(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 76(gene name synonym) psi-mi:"MI:0096"(pull down) Kashuba et al. (2006) imex:IM-14447|pubmed:16257957|mint:MINT-6594475 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-993129|imex:IM-14447-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6VMX|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0044204"(host cell nuclear matrix)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|refseq:YP_401669.1|rcsb pdb:1M05|rcsb pdb:1XR8|rcsb pdb:5WMO interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:5NJ8|reactome:R-HSA-1989781|reactome:R-HSA-211945|reactome:R-HSA-211976|reactome:R-HSA-211981|reactome:R-HSA-8937144|ensembl:ENSG00000106546(gene)|ensembl:ENST00000242057(transcript)|ensembl:ENST00000463496(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001568"(blood vessel development)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002841"(negative regulation of T cell mediated immune response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0005829"(cytosol)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034752"(cytosolic aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|refseq:NP_001612.1|dip:DIP-946N psi-mi:"MI:0469"(intact) - - figure legend:1C, 1D|comment:Interaction carried out in the presence of XAP2. Stability is affected by The presence of XAP1.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2006/08/08 2014/10/16 rogid:0HIls6vxksxriVNTv5M9V6FND8E10377 rogid:7hBqGKPH2nBDWpy9UoQ7+KpY+ic9606 intact-crc:93BE835DBB3A29A9|rigid:kc9vXFVrelLzvLcO2ACd7T+mOKM false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P35869 uniprotkb:O00170 intact:EBI-80780|uniprotkb:A4D130|ensembl:ENSP00000242057|ensembl:ENSP00000436466|uniprotkb:Q13728|uniprotkb:Q13803|uniprotkb:Q13804 intact:EBI-704197|uniprotkb:Q2M3Q2|uniprotkb:Q99606|uniprotkb:A0SZW3|uniprotkb:A0SZW4|uniprotkb:A0SZW5|uniprotkb:A0SZW6|ensembl:ENSP00000279146 psi-mi:ahr_human(display_long)|uniprotkb:AHR(gene name)|psi-mi:AHR(display_short)|uniprotkb:BHLHE76(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 76(gene name synonym) psi-mi:aip_human(display_long)|uniprotkb:Aryl-hydrocarbon receptor-interacting protein(gene name synonym)|uniprotkb:Immunophilin homolog ARA9(gene name synonym)|uniprotkb:HBV X-associated protein 2(gene name synonym)|uniprotkb:AIP(gene name)|psi-mi:AIP(display_short)|uniprotkb:XAP2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kashuba et al. (2006) imex:IM-14447|pubmed:16257957|mint:MINT-6594475 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-993202|imex:IM-14447-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:5NJ8|reactome:R-HSA-1989781|reactome:R-HSA-211945|reactome:R-HSA-211976|reactome:R-HSA-211981|reactome:R-HSA-8937144|ensembl:ENSG00000106546(gene)|ensembl:ENST00000242057(transcript)|ensembl:ENST00000463496(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001568"(blood vessel development)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002841"(negative regulation of T cell mediated immune response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0005829"(cytosol)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034752"(cytosolic aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|refseq:NP_001612.1|dip:DIP-946N refseq:NP_003968.3|refseq:NP_001289888.1|refseq:NP_001289889.1|dip:DIP-34068N|ensembl:ENSG00000110711(gene)|ensembl:ENST00000279146(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0036004"(GAF domain binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031208|interpro:IPR039663|mint:O00170|rcsb pdb:2LKN|rcsb pdb:4AIF|rcsb pdb:4APO|reactome:R-HSA-8937144|reactome:R-HSA-8950505 go:"GO:0005737"(cytoplasm) - - figure legend:3|comment:In the presence of TCDD some localisation to nucleus was found.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2006/08/08 2014/10/16 rogid:7hBqGKPH2nBDWpy9UoQ7+KpY+ic9606 rogid:uCcvOG+bNnmT2zzm58nXhAzKbWo9606 intact-crc:E236889968F8BAB3|rigid:4btggNY8REDwwiFX3WGjtzAxGmM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35869 uniprotkb:O00170 intact:EBI-80780|uniprotkb:A4D130|ensembl:ENSP00000242057|ensembl:ENSP00000436466|uniprotkb:Q13728|uniprotkb:Q13803|uniprotkb:Q13804 intact:EBI-704197|uniprotkb:Q2M3Q2|uniprotkb:Q99606|uniprotkb:A0SZW3|uniprotkb:A0SZW4|uniprotkb:A0SZW5|uniprotkb:A0SZW6|ensembl:ENSP00000279146 psi-mi:ahr_human(display_long)|uniprotkb:AHR(gene name)|psi-mi:AHR(display_short)|uniprotkb:BHLHE76(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 76(gene name synonym) psi-mi:aip_human(display_long)|uniprotkb:Aryl-hydrocarbon receptor-interacting protein(gene name synonym)|uniprotkb:Immunophilin homolog ARA9(gene name synonym)|uniprotkb:HBV X-associated protein 2(gene name synonym)|uniprotkb:AIP(gene name)|psi-mi:AIP(display_short)|uniprotkb:XAP2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kashuba et al. (2006) imex:IM-14447|pubmed:16257957|mint:MINT-6594475 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-993238|imex:IM-14447-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:5NJ8|reactome:R-HSA-1989781|reactome:R-HSA-211945|reactome:R-HSA-211976|reactome:R-HSA-211981|reactome:R-HSA-8937144|ensembl:ENSG00000106546(gene)|ensembl:ENST00000242057(transcript)|ensembl:ENST00000463496(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001568"(blood vessel development)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002841"(negative regulation of T cell mediated immune response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0005829"(cytosol)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034752"(cytosolic aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|refseq:NP_001612.1|dip:DIP-946N refseq:NP_003968.3|refseq:NP_001289888.1|refseq:NP_001289889.1|dip:DIP-34068N|ensembl:ENSG00000110711(gene)|ensembl:ENST00000279146(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0036004"(GAF domain binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031208|interpro:IPR039663|mint:O00170|rcsb pdb:2LKN|rcsb pdb:4AIF|rcsb pdb:4APO|reactome:R-HSA-8937144|reactome:R-HSA-8950505 go:"GO:0005737"(cytoplasm) - - figure legend:4|comment:In the presence of TCDD some localisation to nucleus was found.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2006/08/08 2014/10/16 rogid:7hBqGKPH2nBDWpy9UoQ7+KpY+ic9606 rogid:uCcvOG+bNnmT2zzm58nXhAzKbWo9606 intact-crc:61A3D4A9512901FA|rigid:iD2q3vQSdyr5U0wBSa999cld/L0 false green fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35869 uniprotkb:P12977 intact:EBI-80780|uniprotkb:A4D130|ensembl:ENSP00000242057|ensembl:ENSP00000436466|uniprotkb:Q13728|uniprotkb:Q13803|uniprotkb:Q13804 intact:EBI-993115|uniprotkb:Q66540|uniprotkb:P03202|uniprotkb:Q69021|uniprotkb:Q8AZJ8 psi-mi:ahr_human(display_long)|uniprotkb:AHR(gene name)|psi-mi:AHR(display_short)|uniprotkb:BHLHE76(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 76(gene name synonym) psi-mi:ebna3_ebvb9(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Kashuba et al. (2006) imex:IM-14447|pubmed:16257957|mint:MINT-6594475 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-993238|imex:IM-14447-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:5NJ8|reactome:R-HSA-1989781|reactome:R-HSA-211945|reactome:R-HSA-211976|reactome:R-HSA-211981|reactome:R-HSA-8937144|ensembl:ENSG00000106546(gene)|ensembl:ENST00000242057(transcript)|ensembl:ENST00000463496(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001568"(blood vessel development)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002841"(negative regulation of T cell mediated immune response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0005829"(cytosol)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034752"(cytosolic aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|refseq:NP_001612.1|dip:DIP-946N rcsb pdb:6VMX|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0044204"(host cell nuclear matrix)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|refseq:YP_401669.1|rcsb pdb:1M05|rcsb pdb:1XR8|rcsb pdb:5WMO go:"GO:0005737"(cytoplasm) - - figure legend:4|comment:In the presence of TCDD some localisation to nucleus was found.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2006/08/08 2014/10/16 rogid:7hBqGKPH2nBDWpy9UoQ7+KpY+ic9606 rogid:0HIls6vxksxriVNTv5M9V6FND8E10377 intact-crc:61A3D4A9512901FA|rigid:iD2q3vQSdyr5U0wBSa999cld/L0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35869 uniprotkb:O00170 intact:EBI-80780|uniprotkb:A4D130|ensembl:ENSP00000242057|ensembl:ENSP00000436466|uniprotkb:Q13728|uniprotkb:Q13803|uniprotkb:Q13804 intact:EBI-704197|uniprotkb:Q2M3Q2|uniprotkb:Q99606|uniprotkb:A0SZW3|uniprotkb:A0SZW4|uniprotkb:A0SZW5|uniprotkb:A0SZW6|ensembl:ENSP00000279146 psi-mi:ahr_human(display_long)|uniprotkb:AHR(gene name)|psi-mi:AHR(display_short)|uniprotkb:BHLHE76(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 76(gene name synonym) psi-mi:aip_human(display_long)|uniprotkb:Aryl-hydrocarbon receptor-interacting protein(gene name synonym)|uniprotkb:Immunophilin homolog ARA9(gene name synonym)|uniprotkb:HBV X-associated protein 2(gene name synonym)|uniprotkb:AIP(gene name)|psi-mi:AIP(display_short)|uniprotkb:XAP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kashuba et al. (2006) imex:IM-14447|pubmed:16257957|mint:MINT-6594475 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-993258|imex:IM-14447-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:5NJ8|reactome:R-HSA-1989781|reactome:R-HSA-211945|reactome:R-HSA-211976|reactome:R-HSA-211981|reactome:R-HSA-8937144|ensembl:ENSG00000106546(gene)|ensembl:ENST00000242057(transcript)|ensembl:ENST00000463496(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001568"(blood vessel development)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002841"(negative regulation of T cell mediated immune response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0005829"(cytosol)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034752"(cytosolic aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|refseq:NP_001612.1|dip:DIP-946N refseq:NP_003968.3|refseq:NP_001289888.1|refseq:NP_001289889.1|dip:DIP-34068N|ensembl:ENSG00000110711(gene)|ensembl:ENST00000279146(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0036004"(GAF domain binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031208|interpro:IPR039663|mint:O00170|rcsb pdb:2LKN|rcsb pdb:4AIF|rcsb pdb:4APO|reactome:R-HSA-8937144|reactome:R-HSA-8950505 psi-mi:"MI:0469"(intact) - - figure legend:5|comment:The increase in EBNA3 expression decreased amount of AhR Coprecipitated with XAP2.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2006/08/08 2014/10/16 rogid:7hBqGKPH2nBDWpy9UoQ7+KpY+ic9606 rogid:uCcvOG+bNnmT2zzm58nXhAzKbWo9606 intact-crc:C48D6819BC37D43F|rigid:4btggNY8REDwwiFX3WGjtzAxGmM false green fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P35869 uniprotkb:P12977 intact:EBI-80780|uniprotkb:A4D130|ensembl:ENSP00000242057|ensembl:ENSP00000436466|uniprotkb:Q13728|uniprotkb:Q13803|uniprotkb:Q13804 intact:EBI-993115|uniprotkb:Q66540|uniprotkb:P03202|uniprotkb:Q69021|uniprotkb:Q8AZJ8 psi-mi:ahr_human(display_long)|uniprotkb:AHR(gene name)|psi-mi:AHR(display_short)|uniprotkb:BHLHE76(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 76(gene name synonym) psi-mi:ebna3_ebvb9(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kashuba et al. (2006) imex:IM-14447|pubmed:16257957|mint:MINT-6594475 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-993270|imex:IM-14447-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:5NJ8|reactome:R-HSA-1989781|reactome:R-HSA-211945|reactome:R-HSA-211976|reactome:R-HSA-211981|reactome:R-HSA-8937144|ensembl:ENSG00000106546(gene)|ensembl:ENST00000242057(transcript)|ensembl:ENST00000463496(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001568"(blood vessel development)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002841"(negative regulation of T cell mediated immune response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0005829"(cytosol)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034752"(cytosolic aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|refseq:NP_001612.1|dip:DIP-946N rcsb pdb:6VMX|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0044204"(host cell nuclear matrix)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|refseq:YP_401669.1|rcsb pdb:1M05|rcsb pdb:1XR8|rcsb pdb:5WMO psi-mi:"MI:0469"(intact) - - figure legend:5C, 5D|comment:The increase in XAP2 expression decreased amount of AhR Coprecipitated with EBNA3.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2006/08/08 2014/10/16 rogid:7hBqGKPH2nBDWpy9UoQ7+KpY+ic9606 rogid:0HIls6vxksxriVNTv5M9V6FND8E10377 intact-crc:7E76B8E7E8EF2CFB|rigid:kc9vXFVrelLzvLcO2ACd7T+mOKM false green fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P12977 uniprotkb:P35869 intact:EBI-993115|uniprotkb:Q66540|uniprotkb:P03202|uniprotkb:Q69021|uniprotkb:Q8AZJ8 intact:EBI-80780|uniprotkb:A4D130|ensembl:ENSP00000242057|ensembl:ENSP00000436466|uniprotkb:Q13728|uniprotkb:Q13803|uniprotkb:Q13804 psi-mi:ebna3_ebvb9(display_long)|uniprotkb:Epstein-Barr nuclear antigen 3A(gene name synonym)|uniprotkb:BLRF3-BERF1(orf name)|uniprotkb:EBNA3(gene name)|psi-mi:EBNA3(display_short) psi-mi:ahr_human(display_long)|uniprotkb:AHR(gene name)|psi-mi:AHR(display_short)|uniprotkb:BHLHE76(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 76(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kashuba et al. (2006) imex:IM-14447|pubmed:16257957|mint:MINT-6594475 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-993288|imex:IM-14447-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6VMX|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0044204"(host cell nuclear matrix)|interpro:IPR007706(Epstein-Barr virus nuclear antigen 3)|refseq:YP_401669.1|rcsb pdb:1M05|rcsb pdb:1XR8|rcsb pdb:5WMO interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:5NJ8|reactome:R-HSA-1989781|reactome:R-HSA-211945|reactome:R-HSA-211976|reactome:R-HSA-211981|reactome:R-HSA-8937144|ensembl:ENSG00000106546(gene)|ensembl:ENST00000242057(transcript)|ensembl:ENST00000463496(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001568"(blood vessel development)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002841"(negative regulation of T cell mediated immune response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0005829"(cytosol)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034752"(cytosolic aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|refseq:NP_001612.1|dip:DIP-946N psi-mi:"MI:0469"(intact) - - figure legend:6|comment:Interaction was increased in the presence of TCDD and ARNT together. Interaction is decreased in the presence of ARNT or TCDD or XAP2 alone. The decrease was maximum in the presence of both XAP2 and ARNT.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2006/08/08 2014/10/16 rogid:0HIls6vxksxriVNTv5M9V6FND8E10377 rogid:7hBqGKPH2nBDWpy9UoQ7+KpY+ic9606 intact-crc:C84C22DD1FCE2D88|rigid:kc9vXFVrelLzvLcO2ACd7T+mOKM false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)