#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32832 uniprotkb:Q06639 intact:EBI-12202|uniprotkb:D6VZR4|ensemblfungi:YMR091C intact:EBI-22058|uniprotkb:D6VST2|ensemblfungi:YDR303C psi-mi:rsc7_yeast(display_long)|uniprotkb:RSC7(gene name synonym)|uniprotkb:YM9582.16C(orf name)|uniprotkb:NPL6(gene name)|psi-mi:NPL6(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 7(gene name synonym)|uniprotkb:Nuclear protein localization protein 6(gene name synonym)|uniprotkb:YMR091C(locus name) psi-mi:rsc3_yeast(display_long)|uniprotkb:Remodel the structure of chromatin complex subunit 3(gene name synonym)|uniprotkb:RSC3(gene name)|psi-mi:RSC3(display_short)|uniprotkb:YDR303C(locus name)|uniprotkb:D9740.13(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877616|imex:IM-19327-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR091C(gene)|ensemblfungi:YMR091C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR013933(Chromatin remodelling complex, RSC SWI/SNF subunit Rsc7/Swp82)|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92|refseq:NP_013809.1|sgd:S000004697|dip:DIP-1477N|mint:P32832 sgd:S000002711|refseq:NP_010589.3|dip:DIP-5867N|ensemblfungi:YDR303C(gene)|ensemblfungi:YDR303C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0043044"|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0043565"(sequence-specific DNA binding)|mint:Q06639 - - - comment:Npl6/Rsc7 was able to co-precipitate members of the RSC complex including Sth1, Rsc3, Rsc30, Arp7 and Arp9. These interactions were stable under stringent wash conditions and confirms Npl6/Rsc7 as a stable component of the RSC complex.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:HHFb1+GvDMf/wVetwORrX6vmJZo559292 rogid:Mn5cFKxVYEpAAQz7QSnxOVtr4lQ559292 intact-crc:9D9C5180F5FB8C4F|rigid:NblFVrDSDGPhJyDHmlle5v5nZKA false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32832 uniprotkb:P38781 intact:EBI-12202|uniprotkb:D6VZR4|ensemblfungi:YMR091C intact:EBI-24549|uniprotkb:D3DL05|ensemblfungi:YHR056C psi-mi:rsc7_yeast(display_long)|uniprotkb:RSC7(gene name synonym)|uniprotkb:YM9582.16C(orf name)|uniprotkb:NPL6(gene name)|psi-mi:NPL6(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 7(gene name synonym)|uniprotkb:Nuclear protein localization protein 6(gene name synonym)|uniprotkb:YMR091C(locus name) psi-mi:rsc30_yeast(display_long)|uniprotkb:RSC30(gene name)|psi-mi:RSC30(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 30(gene name synonym)|uniprotkb:YHR056C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877616|imex:IM-19327-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR091C(gene)|ensemblfungi:YMR091C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR013933(Chromatin remodelling complex, RSC SWI/SNF subunit Rsc7/Swp82)|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92|refseq:NP_013809.1|sgd:S000004697|dip:DIP-1477N|mint:P32832 refseq:NP_011923.2|sgd:S000001098|dip:DIP-4275N|ensemblfungi:YHR056C(gene)|ensemblfungi:YHR056C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016586"(RSC-type complex)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3 - - - comment:Npl6/Rsc7 was able to co-precipitate members of the RSC complex including Sth1, Rsc3, Rsc30, Arp7 and Arp9. These interactions were stable under stringent wash conditions and confirms Npl6/Rsc7 as a stable component of the RSC complex.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:HHFb1+GvDMf/wVetwORrX6vmJZo559292 rogid:NzGOxIaNyDat2EcQdWPobugunh0559292 intact-crc:9D9C5180F5FB8C4F|rigid:NblFVrDSDGPhJyDHmlle5v5nZKA false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32832 uniprotkb:P32597 intact:EBI-12202|uniprotkb:D6VZR4|ensemblfungi:YMR091C intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W psi-mi:rsc7_yeast(display_long)|uniprotkb:RSC7(gene name synonym)|uniprotkb:YM9582.16C(orf name)|uniprotkb:NPL6(gene name)|psi-mi:NPL6(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 7(gene name synonym)|uniprotkb:Nuclear protein localization protein 6(gene name synonym)|uniprotkb:YMR091C(locus name) psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877616|imex:IM-19327-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR091C(gene)|ensemblfungi:YMR091C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR013933(Chromatin remodelling complex, RSC SWI/SNF subunit Rsc7/Swp82)|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92|refseq:NP_013809.1|sgd:S000004697|dip:DIP-1477N|mint:P32832 refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 - - crc64:269A91BD853C20D0 comment:Npl6/Rsc7 was able to co-precipitate members of the RSC complex including Sth1, Rsc3, Rsc30, Arp7 and Arp9. These interactions were stable under stringent wash conditions and confirms Npl6/Rsc7 as a stable component of the RSC complex.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:HHFb1+GvDMf/wVetwORrX6vmJZo559292 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 intact-crc:9D9C5180F5FB8C4F|rigid:NblFVrDSDGPhJyDHmlle5v5nZKA false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32832 uniprotkb:Q12406 intact:EBI-12202|uniprotkb:D6VZR4|ensemblfungi:YMR091C intact:EBI-2962|uniprotkb:D6W444|ensemblfungi:YPR034W psi-mi:rsc7_yeast(display_long)|uniprotkb:RSC7(gene name synonym)|uniprotkb:YM9582.16C(orf name)|uniprotkb:NPL6(gene name)|psi-mi:NPL6(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 7(gene name synonym)|uniprotkb:Nuclear protein localization protein 6(gene name synonym)|uniprotkb:YMR091C(locus name) psi-mi:arp7_yeast(display_long)|uniprotkb:ARP7(gene name)|psi-mi:ARP7(display_short)|uniprotkb:SWP61(gene name synonym)|uniprotkb:YPR034W(locus name)|uniprotkb:YP9367.14(orf name)|uniprotkb:Actin-like protein ARP7(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein ARP7(gene name synonym)|uniprotkb:SWI/SNF complex component ARP7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877616|imex:IM-19327-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR091C(gene)|ensemblfungi:YMR091C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR013933(Chromatin remodelling complex, RSC SWI/SNF subunit Rsc7/Swp82)|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92|refseq:NP_013809.1|sgd:S000004697|dip:DIP-1477N|mint:P32832 refseq:NP_015359.1|sgd:S000006238|dip:DIP-6351N|mint:Q12406|ensemblfungi:YPR034W(gene)|ensemblfungi:YPR034W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016586"(RSC-type complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004000(Actin/actin-like)|interpro:IPR043129|rcsb pdb:3WEE|rcsb pdb:4I6M|rcsb pdb:5TGC|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6UXW|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|rcsb pdb:7C4J|reactome:R-SCE-3214858 - - crc64:8E105921576FA213 comment:Npl6/Rsc7 was able to co-precipitate members of the RSC complex including Sth1, Rsc3, Rsc30, Arp7 and Arp9. These interactions were stable under stringent wash conditions and confirms Npl6/Rsc7 as a stable component of the RSC complex.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:HHFb1+GvDMf/wVetwORrX6vmJZo559292 rogid:6v4mZkPazGyh2qTqQGnivh6uHAc559292 intact-crc:9D9C5180F5FB8C4F|rigid:NblFVrDSDGPhJyDHmlle5v5nZKA false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32832 uniprotkb:Q05123 intact:EBI-12202|uniprotkb:D6VZR4|ensemblfungi:YMR091C intact:EBI-2972|uniprotkb:D6VZK8|ensemblfungi:YMR033W psi-mi:rsc7_yeast(display_long)|uniprotkb:RSC7(gene name synonym)|uniprotkb:YM9582.16C(orf name)|uniprotkb:NPL6(gene name)|psi-mi:NPL6(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 7(gene name synonym)|uniprotkb:Nuclear protein localization protein 6(gene name synonym)|uniprotkb:YMR091C(locus name) psi-mi:arp9_yeast(display_long)|uniprotkb:ARP9(gene name)|psi-mi:ARP9(display_short)|uniprotkb:SWP59(gene name synonym)|uniprotkb:YMR033W(locus name)|uniprotkb:YM9973.07(orf name)|uniprotkb:Chromatin structure-remodeling complex protein ARP9(gene name synonym)|uniprotkb:SWI/SNF complex component ARP9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877616|imex:IM-19327-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR091C(gene)|ensemblfungi:YMR091C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR013933(Chromatin remodelling complex, RSC SWI/SNF subunit Rsc7/Swp82)|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92|refseq:NP_013809.1|sgd:S000004697|dip:DIP-1477N|mint:P32832 refseq:NP_013747.1|sgd:S000004636|dip:DIP-6709N|mint:Q05123|rcsb pdb:6VZG|rcsb pdb:7C4J|reactome:R-SCE-3214858|ensemblfungi:YMR033W(gene)|ensemblfungi:YMR033W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004000(Actin/actin-like)|interpro:IPR043129|rcsb pdb:3WEE|rcsb pdb:4I6M|rcsb pdb:5TGC|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6UXW|rcsb pdb:6V92|rcsb pdb:6VZ4 - - crc64:EE1AB154A906420E comment:Npl6/Rsc7 was able to co-precipitate members of the RSC complex including Sth1, Rsc3, Rsc30, Arp7 and Arp9. These interactions were stable under stringent wash conditions and confirms Npl6/Rsc7 as a stable component of the RSC complex.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:HHFb1+GvDMf/wVetwORrX6vmJZo559292 rogid:bn+KSKckXTEdvwOpf5DiKsRy484559292 intact-crc:9D9C5180F5FB8C4F|rigid:NblFVrDSDGPhJyDHmlle5v5nZKA false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43554 uniprotkb:P53628 intact:EBI-22851|uniprotkb:D6VTI1|ensemblfungi:YFL049W intact:EBI-17564|uniprotkb:D6W1J8|ensemblfungi:YNR023W psi-mi:swp82_yeast(display_long)|uniprotkb:SWP82(gene name)|psi-mi:SWP82(display_short)|uniprotkb:YFL049W(locus name) psi-mi:snf12_yeast(display_long)|uniprotkb:SNF12(gene name)|psi-mi:SNF12(display_short)|uniprotkb:SWP73(gene name synonym)|uniprotkb:YNR023W(locus name)|uniprotkb:N3224(orf name)|uniprotkb:SWI/SNF complex component SWP73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877744|imex:IM-19327-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116605.1|sgd:S000001845|dip:DIP-4202N|mint:P43554|ensemblfungi:YFL049W(gene)|ensemblfungi:YFL049W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR013933(Chromatin remodelling complex, RSC SWI/SNF subunit Rsc7/Swp82)|rcsb pdb:7C4J|reactome:R-SCE-4551638 refseq:NP_014420.1|sgd:S000005306|ensemblfungi:YNR023W(gene)|ensemblfungi:YNR023W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061412"(positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation)|interpro:IPR036885|rcsb pdb:6UXV|rcsb pdb:6UXW|rcsb pdb:7C4J|reactome:R-SCE-3214858|dip:DIP-2443N|mint:P53628 - crc64:A8AC00CAC8F0ED0E crc64:CD6E61EEEE85098C comment:Swp82 is a member of the swi/snf complex since it efficiently coprecipitated with Swi3 and Snf12 and remained associated even under stringent wash conditions.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:/Pn3lcaaJtD+1BiVBpt99lcvSeo559292 rogid:ZlOLOqBhD/vTk/ElJEQCUqB3QmA559292 intact-crc:23644A2A21CAC7C3|rigid:SZiOAU9DVAPmexP3Lpix48b3LM4 false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43554 uniprotkb:P32591 intact:EBI-22851|uniprotkb:D6VTI1|ensemblfungi:YFL049W intact:EBI-18622|ensemblfungi:YJL176C|uniprotkb:D6VW13 psi-mi:swp82_yeast(display_long)|uniprotkb:SWP82(gene name)|psi-mi:SWP82(display_short)|uniprotkb:YFL049W(locus name) psi-mi:swi3_yeast(display_long)|uniprotkb:SWI3(gene name)|psi-mi:SWI3(display_short)|uniprotkb:TYE2(gene name synonym)|uniprotkb:J0495(orf name)|uniprotkb:YJL176C(locus name)|uniprotkb:Transcription regulatory protein SWI3(gene name synonym)|uniprotkb:Transcription factor TYE2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877744|imex:IM-19327-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116605.1|sgd:S000001845|dip:DIP-4202N|mint:P43554|ensemblfungi:YFL049W(gene)|ensemblfungi:YFL049W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR013933(Chromatin remodelling complex, RSC SWI/SNF subunit Rsc7/Swp82)|rcsb pdb:7C4J|reactome:R-SCE-4551638 ensemblfungi:YJL176C(gene)|go:"GO:0000436"(carbon catabolite activation of transcription from RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0031496"(positive regulation of mating type switching)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032451|interpro:IPR036388|rcsb pdb:2FQ3|rcsb pdb:6L9J|rcsb pdb:6UXV|rcsb pdb:6UXW|rcsb pdb:7C4J|reactome:R-SCE-3214858|ensemblfungi:YJL176C_mRNA(transcript)|refseq:NP_012359.1|sgd:S000003712|dip:DIP-2471N|mint:P32591 - crc64:A8AC00CAC8F0ED0E crc64:DBA2E2022F15F9A6 comment:Swp82 is a member of the swi/snf complex since it efficiently coprecipitated with Swi3 and Snf12 and remained associated even under stringent wash conditions.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:/Pn3lcaaJtD+1BiVBpt99lcvSeo559292 rogid:nS1Z019Zv1HTDCHajHw2lvqLt14559292 intact-crc:23644A2A21CAC7C3|rigid:SZiOAU9DVAPmexP3Lpix48b3LM4 false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38210 uniprotkb:Q05123 intact:EBI-21189|uniprotkb:D6VPZ4|ensemblfungi:YBL006C intact:EBI-2972|uniprotkb:D6VZK8|ensemblfungi:YMR033W psi-mi:ldb7_yeast(display_long)|uniprotkb:RSC14(gene name synonym)|uniprotkb:YBL0322(orf name)|uniprotkb:YBL006C(locus name)|uniprotkb:LDB7(gene name)|psi-mi:LDB7(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 14(gene name synonym)|uniprotkb:Low dye-binding protein 7(gene name synonym) psi-mi:arp9_yeast(display_long)|uniprotkb:ARP9(gene name)|psi-mi:ARP9(display_short)|uniprotkb:SWP59(gene name synonym)|uniprotkb:YMR033W(locus name)|uniprotkb:YM9973.07(orf name)|uniprotkb:Chromatin structure-remodeling complex protein ARP9(gene name synonym)|uniprotkb:SWI/SNF complex component ARP9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877802|imex:IM-19327-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009547.2|sgd:S000000102|dip:DIP-3927N|ensemblfungi:YBL006C(gene)|ensemblfungi:YBL006C_mRNA(transcript)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR013895(Chromatin remodelling complex RSC, subunit Rsc14)|rcsb pdb:6V8O|rcsb pdb:6V92 refseq:NP_013747.1|sgd:S000004636|dip:DIP-6709N|mint:Q05123|rcsb pdb:6VZG|rcsb pdb:7C4J|reactome:R-SCE-3214858|ensemblfungi:YMR033W(gene)|ensemblfungi:YMR033W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004000(Actin/actin-like)|interpro:IPR043129|rcsb pdb:3WEE|rcsb pdb:4I6M|rcsb pdb:5TGC|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6UXW|rcsb pdb:6V92|rcsb pdb:6VZ4 - crc64:9A4F882DB7AA1EC9 crc64:EE1AB154A906420E comment:Ldb7/Rsc14 coprecipitates with other members of the RSC complex including Arp9 and Sth1 and the interaction remains stable under stringent wash conditions.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:bH5HK/FQctilmIy/ZeBlCrhJTUM559292 rogid:bn+KSKckXTEdvwOpf5DiKsRy484559292 intact-crc:EEDC4F2F4B670BEE|rigid:iQ/YyiokFK6jM9nKIc7HlIaOips false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38210 uniprotkb:P32597 intact:EBI-21189|uniprotkb:D6VPZ4|ensemblfungi:YBL006C intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W psi-mi:ldb7_yeast(display_long)|uniprotkb:RSC14(gene name synonym)|uniprotkb:YBL0322(orf name)|uniprotkb:YBL006C(locus name)|uniprotkb:LDB7(gene name)|psi-mi:LDB7(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 14(gene name synonym)|uniprotkb:Low dye-binding protein 7(gene name synonym) psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877802|imex:IM-19327-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009547.2|sgd:S000000102|dip:DIP-3927N|ensemblfungi:YBL006C(gene)|ensemblfungi:YBL006C_mRNA(transcript)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR013895(Chromatin remodelling complex RSC, subunit Rsc14)|rcsb pdb:6V8O|rcsb pdb:6V92 refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 - crc64:9A4F882DB7AA1EC9 crc64:269A91BD853C20D0 comment:Ldb7/Rsc14 coprecipitates with other members of the RSC complex including Arp9 and Sth1 and the interaction remains stable under stringent wash conditions.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:bH5HK/FQctilmIy/ZeBlCrhJTUM559292 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 intact-crc:EEDC4F2F4B670BEE|rigid:iQ/YyiokFK6jM9nKIc7HlIaOips false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43609 uniprotkb:P32597 intact:EBI-23005|uniprotkb:Q6B289|uniprotkb:D6VTS0|ensemblfungi:YFR037C intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W psi-mi:rsc8_yeast(display_long)|uniprotkb:RSC8(gene name)|psi-mi:RSC8(display_short)|uniprotkb:YFR037C(locus name)|uniprotkb:SWH3(gene name synonym)|uniprotkb:Remodel the structure of chromatin complex subunit 8(gene name synonym)|uniprotkb:SWI3 homolog(gene name synonym) psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877973|imex:IM-19327-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001933|refseq:NP_116695.3|dip:DIP-1478N|mint:P43609|interpro:IPR041984|interpro:IPR043145|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92|reactome:R-SCE-3214858|ensemblfungi:YFR037C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016586"(RSC-type complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|ensemblfungi:YFR037C(gene)|interpro:IPR032451|interpro:IPR036388 refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 - crc64:D3D3120397CF0058 crc64:269A91BD853C20D0 comment:Rsc8 protein levels were greatly reduced in a rsc7-deficient mutant strain confirming that Npl6/Rsc7 contributes to the general assembly of the RSC complex. Rsc3 association with RSC8 was severely reduced in the rsc7-deficient mutant strain.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:KpjkVJpv/5nqhpXBAhQZ3CzUr9k559292 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 intact-crc:B5B284210A1F8CC4|rigid:X7/RDS96IqRsAUSVo9l7djaN1/0 false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43609 uniprotkb:Q06639 intact:EBI-23005|uniprotkb:Q6B289|uniprotkb:D6VTS0|ensemblfungi:YFR037C intact:EBI-22058|uniprotkb:D6VST2|ensemblfungi:YDR303C psi-mi:rsc8_yeast(display_long)|uniprotkb:RSC8(gene name)|psi-mi:RSC8(display_short)|uniprotkb:YFR037C(locus name)|uniprotkb:SWH3(gene name synonym)|uniprotkb:Remodel the structure of chromatin complex subunit 8(gene name synonym)|uniprotkb:SWI3 homolog(gene name synonym) psi-mi:rsc3_yeast(display_long)|uniprotkb:Remodel the structure of chromatin complex subunit 3(gene name synonym)|uniprotkb:RSC3(gene name)|psi-mi:RSC3(display_short)|uniprotkb:YDR303C(locus name)|uniprotkb:D9740.13(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877973|imex:IM-19327-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001933|refseq:NP_116695.3|dip:DIP-1478N|mint:P43609|interpro:IPR041984|interpro:IPR043145|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92|reactome:R-SCE-3214858|ensemblfungi:YFR037C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016586"(RSC-type complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|ensemblfungi:YFR037C(gene)|interpro:IPR032451|interpro:IPR036388 sgd:S000002711|refseq:NP_010589.3|dip:DIP-5867N|ensemblfungi:YDR303C(gene)|ensemblfungi:YDR303C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0043044"|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0043565"(sequence-specific DNA binding)|mint:Q06639 - crc64:D3D3120397CF0058 - comment:Rsc8 protein levels were greatly reduced in a rsc7-deficient mutant strain confirming that Npl6/Rsc7 contributes to the general assembly of the RSC complex. Rsc3 association with RSC8 was severely reduced in the rsc7-deficient mutant strain.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:KpjkVJpv/5nqhpXBAhQZ3CzUr9k559292 rogid:Mn5cFKxVYEpAAQz7QSnxOVtr4lQ559292 intact-crc:B5B284210A1F8CC4|rigid:X7/RDS96IqRsAUSVo9l7djaN1/0 false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43609 uniprotkb:Q06488 intact:EBI-23005|uniprotkb:Q6B289|uniprotkb:D6VTS0|ensemblfungi:YFR037C intact:EBI-16198|ensemblfungi:YLR357W|uniprotkb:D6VYZ5 psi-mi:rsc8_yeast(display_long)|uniprotkb:RSC8(gene name)|psi-mi:RSC8(display_short)|uniprotkb:YFR037C(locus name)|uniprotkb:SWH3(gene name synonym)|uniprotkb:Remodel the structure of chromatin complex subunit 8(gene name synonym)|uniprotkb:SWI3 homolog(gene name synonym) psi-mi:rsc2_yeast(display_long)|uniprotkb:RSC2(gene name)|psi-mi:RSC2(display_short)|uniprotkb:RSC complex subunit RSC2(gene name synonym)|uniprotkb:L9638.1(orf name)|uniprotkb:YLR357W(locus name)|uniprotkb:Remodel the structure of chromatin complex subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877991|imex:IM-19327-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001933|refseq:NP_116695.3|dip:DIP-1478N|mint:P43609|interpro:IPR041984|interpro:IPR043145|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92|reactome:R-SCE-3214858|ensemblfungi:YFR037C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016586"(RSC-type complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|ensemblfungi:YFR037C(gene)|interpro:IPR032451|interpro:IPR036388 ensemblfungi:YLR357W(gene)|ensemblfungi:YLR357W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003682"(chromatin binding)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016586"(RSC-type complex)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|interpro:IPR037382|interpro:IPR043151|rcsb pdb:4BB7|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6V8O|rcsb pdb:6V92|reactome:R-SCE-3214858|go:"GO:0042173"(regulation of sporulation resulting in formation of a cellular spore)|go:"GO:0043044"|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027180|interpro:IPR035700|interpro:IPR036427|refseq:NP_013461.1|sgd:S000004349|dip:DIP-863N|mint:Q06488 - crc64:D3D3120397CF0058 crc64:7867866FD973F188 comment:"In rsc14-deficient mutant strain Rsc8 coprecipitates with Sth1 and Rsc2 normally, whereas its association with Rsc3 and Rsc30 is severely diminished. This confirms that Ldb7/Rsc14 helps (together with Npl6/Rsc7) the Rsc3/Rsc30 heterodimer assemble into RSC."|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:KpjkVJpv/5nqhpXBAhQZ3CzUr9k559292 rogid:m8jAmTXXCyoUnJPmorW0A7/o2js559292 intact-crc:8E26529C94797C6D|rigid:CNEiBZWuJ0hYrpvWa4BXalegO8k false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43609 uniprotkb:P38781 intact:EBI-23005|uniprotkb:Q6B289|uniprotkb:D6VTS0|ensemblfungi:YFR037C intact:EBI-24549|uniprotkb:D3DL05|ensemblfungi:YHR056C psi-mi:rsc8_yeast(display_long)|uniprotkb:RSC8(gene name)|psi-mi:RSC8(display_short)|uniprotkb:YFR037C(locus name)|uniprotkb:SWH3(gene name synonym)|uniprotkb:Remodel the structure of chromatin complex subunit 8(gene name synonym)|uniprotkb:SWI3 homolog(gene name synonym) psi-mi:rsc30_yeast(display_long)|uniprotkb:RSC30(gene name)|psi-mi:RSC30(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 30(gene name synonym)|uniprotkb:YHR056C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877991|imex:IM-19327-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001933|refseq:NP_116695.3|dip:DIP-1478N|mint:P43609|interpro:IPR041984|interpro:IPR043145|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92|reactome:R-SCE-3214858|ensemblfungi:YFR037C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016586"(RSC-type complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|ensemblfungi:YFR037C(gene)|interpro:IPR032451|interpro:IPR036388 refseq:NP_011923.2|sgd:S000001098|dip:DIP-4275N|ensemblfungi:YHR056C(gene)|ensemblfungi:YHR056C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016586"(RSC-type complex)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3 - crc64:D3D3120397CF0058 - comment:"In rsc14-deficient mutant strain Rsc8 coprecipitates with Sth1 and Rsc2 normally, whereas its association with Rsc3 and Rsc30 is severely diminished. This confirms that Ldb7/Rsc14 helps (together with Npl6/Rsc7) the Rsc3/Rsc30 heterodimer assemble into RSC."|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:KpjkVJpv/5nqhpXBAhQZ3CzUr9k559292 rogid:NzGOxIaNyDat2EcQdWPobugunh0559292 intact-crc:8E26529C94797C6D|rigid:CNEiBZWuJ0hYrpvWa4BXalegO8k false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43609 uniprotkb:P32597 intact:EBI-23005|uniprotkb:Q6B289|uniprotkb:D6VTS0|ensemblfungi:YFR037C intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W psi-mi:rsc8_yeast(display_long)|uniprotkb:RSC8(gene name)|psi-mi:RSC8(display_short)|uniprotkb:YFR037C(locus name)|uniprotkb:SWH3(gene name synonym)|uniprotkb:Remodel the structure of chromatin complex subunit 8(gene name synonym)|uniprotkb:SWI3 homolog(gene name synonym) psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877991|imex:IM-19327-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001933|refseq:NP_116695.3|dip:DIP-1478N|mint:P43609|interpro:IPR041984|interpro:IPR043145|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92|reactome:R-SCE-3214858|ensemblfungi:YFR037C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016586"(RSC-type complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|ensemblfungi:YFR037C(gene)|interpro:IPR032451|interpro:IPR036388 refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 - crc64:D3D3120397CF0058 crc64:269A91BD853C20D0 comment:"In rsc14-deficient mutant strain Rsc8 coprecipitates with Sth1 and Rsc2 normally, whereas its association with Rsc3 and Rsc30 is severely diminished. This confirms that Ldb7/Rsc14 helps (together with Npl6/Rsc7) the Rsc3/Rsc30 heterodimer assemble into RSC."|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:KpjkVJpv/5nqhpXBAhQZ3CzUr9k559292 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 intact-crc:8E26529C94797C6D|rigid:CNEiBZWuJ0hYrpvWa4BXalegO8k false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43609 uniprotkb:Q06639 intact:EBI-23005|uniprotkb:Q6B289|uniprotkb:D6VTS0|ensemblfungi:YFR037C intact:EBI-22058|uniprotkb:D6VST2|ensemblfungi:YDR303C psi-mi:rsc8_yeast(display_long)|uniprotkb:RSC8(gene name)|psi-mi:RSC8(display_short)|uniprotkb:YFR037C(locus name)|uniprotkb:SWH3(gene name synonym)|uniprotkb:Remodel the structure of chromatin complex subunit 8(gene name synonym)|uniprotkb:SWI3 homolog(gene name synonym) psi-mi:rsc3_yeast(display_long)|uniprotkb:Remodel the structure of chromatin complex subunit 3(gene name synonym)|uniprotkb:RSC3(gene name)|psi-mi:RSC3(display_short)|uniprotkb:YDR303C(locus name)|uniprotkb:D9740.13(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-877991|imex:IM-19327-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001933|refseq:NP_116695.3|dip:DIP-1478N|mint:P43609|interpro:IPR041984|interpro:IPR043145|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|rcsb pdb:6V92|reactome:R-SCE-3214858|ensemblfungi:YFR037C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016586"(RSC-type complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|ensemblfungi:YFR037C(gene)|interpro:IPR032451|interpro:IPR036388 sgd:S000002711|refseq:NP_010589.3|dip:DIP-5867N|ensemblfungi:YDR303C(gene)|ensemblfungi:YDR303C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0043044"|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0043565"(sequence-specific DNA binding)|mint:Q06639 - crc64:D3D3120397CF0058 - comment:"In rsc14-deficient mutant strain Rsc8 coprecipitates with Sth1 and Rsc2 normally, whereas its association with Rsc3 and Rsc30 is severely diminished. This confirms that Ldb7/Rsc14 helps (together with Npl6/Rsc7) the Rsc3/Rsc30 heterodimer assemble into RSC."|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:KpjkVJpv/5nqhpXBAhQZ3CzUr9k559292 rogid:Mn5cFKxVYEpAAQz7QSnxOVtr4lQ559292 intact-crc:8E26529C94797C6D|rigid:CNEiBZWuJ0hYrpvWa4BXalegO8k false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32597 uniprotkb:P38210 intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W intact:EBI-21189|uniprotkb:D6VPZ4|ensemblfungi:YBL006C psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:ldb7_yeast(display_long)|uniprotkb:RSC14(gene name synonym)|uniprotkb:YBL0322(orf name)|uniprotkb:YBL006C(locus name)|uniprotkb:LDB7(gene name)|psi-mi:LDB7(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 14(gene name synonym)|uniprotkb:Low dye-binding protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wilson et al. (2006) pubmed:16204215|imex:IM-19327 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-878034|imex:IM-19327-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 refseq:NP_009547.2|sgd:S000000102|dip:DIP-3927N|ensemblfungi:YBL006C(gene)|ensemblfungi:YBL006C_mRNA(transcript)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR013895(Chromatin remodelling complex RSC, subunit Rsc14)|rcsb pdb:6V8O|rcsb pdb:6V92 - crc64:269A91BD853C20D0 crc64:9A4F882DB7AA1EC9 comment:Shows that Rsc7 is not required for Ldb7/Rsc14 to assemble into RSC since there was normal association between Ldb7/Rsc14 and Sth1 in an rsc7-deficient mutant strain.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/08 2014/10/16 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 rogid:bH5HK/FQctilmIy/ZeBlCrhJTUM559292 intact-crc:EB756EE5925F5841|rigid:1KpRLfpL5uS58Pfz0aKR8tWwkvo false - ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)