#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O60132	uniprotkb:O74304	intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep"	intact:EBI-1099995|uniprotkb:Q9P7R1|uniprotkb:Q9UTP1|uniprotkb:Q9UTR3|ensemblfungi:"SPAC1006.09.1:pep"	psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym)	psi-mi:win1_schpo(display_long)|uniprotkb:win1(gene name)|psi-mi:win1(display_short)|uniprotkb:SPAC1006.09(orf name)|uniprotkb:SPAPJ730.01(orf name)|uniprotkb:SPAC1250.06c(orf name)	psi-mi:"MI:0018"(two hybrid)	Tatebe et al. (2005)	pubmed:15936270|imex:IM-19102	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1099981|imex:IM-19102-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028	ensemblfungi:SPAC1006.09.1(transcript)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|ensemblfungi:SPAC1006.09(gene)|go:"GO:1990315"(Mcs4 RR-MAPKKK complex)|refseq:NP_594856.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR017240(MAP kinase kinase kinase, SSK22)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)	-	-	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/09/27	2014/10/16	rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812	rogid:uFyY7Scuh87LezYSqTB8GybAP58284812	intact-crc:74D7A93CCB7AC17E|rigid:QxapwtpQKQGe9o9wMSlLf4BeWV8	false	necessary binding region:599-821	necessary binding region:282-1123	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:O60132	uniprotkb:O74304	intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep"	intact:EBI-1099995|uniprotkb:Q9P7R1|uniprotkb:Q9UTP1|uniprotkb:Q9UTR3|ensemblfungi:"SPAC1006.09.1:pep"	psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym)	psi-mi:win1_schpo(display_long)|uniprotkb:win1(gene name)|psi-mi:win1(display_short)|uniprotkb:SPAC1006.09(orf name)|uniprotkb:SPAPJ730.01(orf name)|uniprotkb:SPAC1250.06c(orf name)	psi-mi:"MI:0096"(pull down)	Tatebe et al. (2005)	pubmed:15936270|imex:IM-19102	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1100037|imex:IM-19102-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028	ensemblfungi:SPAC1006.09.1(transcript)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|ensemblfungi:SPAC1006.09(gene)|go:"GO:1990315"(Mcs4 RR-MAPKKK complex)|refseq:NP_594856.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR017240(MAP kinase kinase kinase, SSK22)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)	-	-	-	figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/27	2014/10/16	rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812	rogid:uFyY7Scuh87LezYSqTB8GybAP58284812	intact-crc:A5BA65C8F70D1D67|rigid:QxapwtpQKQGe9o9wMSlLf4BeWV8	false	glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60132	uniprotkb:P87061	intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep"	intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep"	psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym)	psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Tatebe et al. (2005)	pubmed:15936270|imex:IM-19102	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1100138|imex:IM-19102-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028	refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip)	-	-	-	figure legend:Figure 4B.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/09/27	2014/10/16	rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812	rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812	intact-crc:13DB427FC5E9244C|rigid:qlHBW+ljlZdXeyOKjdaK/H/Hx7Y	false	calmodulin binding peptide plus protein a tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60132	uniprotkb:P87061	intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep"	intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep"	psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym)	psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym)	psi-mi:"MI:0399"(two hybrid fragment pooling approach)	Tatebe et al. (2005)	pubmed:15936270|imex:IM-19102	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1103170|imex:IM-19102-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028	refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip)	-	-	-	comment:"Tea1 interacts with Tea4 in vivo to form a complex and they are also shown to colocalize at cell ends (Figure 4C). Tea4 is required for normal bipolar tea1 localization. In tea4-depleted cells, tea1 was highly concentrated at one end with the other end showing significantly less tea1-GFP dots (Figure 5A)."|figure legend:4C 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/09/27	2014/10/16	rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812	rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812	intact-crc:5CFBE50D46204EF6|rigid:qlHBW+ljlZdXeyOKjdaK/H/Hx7Y	false	red fluorescent protein tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)