#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O95400 uniprotkb:P83876 intact:EBI-768015|uniprotkb:Q9ULP2|uniprotkb:B2RDX2|ensembl:ENSP00000304903|ensembl:ENSP00000456935 intact:EBI-746539|uniprotkb:O14834|uniprotkb:B2RC18|ensembl:ENSP00000269601 psi-mi:cd2b2_human(display_long)|uniprotkb:CD2BP2(gene name)|psi-mi:CD2BP2(display_short)|uniprotkb:KIAA1178(gene name synonym)|uniprotkb:U5 snRNP 52K protein(gene name synonym) psi-mi:txn4a_human(display_long)|uniprotkb:Thioredoxin-like U5 snRNP protein U5-15kD(gene name synonym)|uniprotkb:Spliceosomal U5 snRNP-specific 15 kDa protein(gene name synonym)|uniprotkb:DIM1 protein homolog(gene name synonym)|uniprotkb:TXNL4A(gene name)|psi-mi:TXNL4A(display_short)|uniprotkb:DIM1(gene name synonym)|uniprotkb:TXNL4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Laggerbauer et al. (2005) pubmed:15840814|mint:MINT-5217675 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7595892|mint:MINT-1783263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230575.1|refseq:NP_006101.1|ensembl:ENSG00000169217(gene)|ensembl:ENST00000305596(transcript)|ensembl:ENST00000569466(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR003169(GYF)|interpro:IPR035445|interpro:IPR039905|mint:O95400|rcsb pdb:1GYF|rcsb pdb:1L2Z|rcsb pdb:1SYX|rcsb pdb:4BWS|reactome:R-HSA-72163|mint:MINT-1783265(identity) refseq:NP_006692.1|refseq:NP_001290400.1|refseq:NP_001292486.1|refseq:NP_001292492.1|refseq:NP_001292493.1|ensembl:ENSG00000141759(gene)|ensembl:ENST00000269601(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0051301"(cell division)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:1PQN|rcsb pdb:1QGV|rcsb pdb:1SYX|rcsb pdb:3JCR|rcsb pdb:4BWQ|rcsb pdb:4BWS|rcsb pdb:4CDO|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0005682"(U5 snRNP)|mint:MINT-1783264(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5A|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/03/13 2014/10/16 rogid:eE6hXTyt05DhzzofcS/QJmUsLEY9606 rogid:gGYj9Meks26JpYxw6wB5S2vIrkE9606 intact-crc:E4F805731AA92E71|rigid:DVDcYkBkEz0xSnK7nKeg4nstdVU false binding-associated region:256-341(MINT-1783282)|tag:?-?(MINT-1783275) tag:?-?(MINT-1783267) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95400 uniprotkb:O94906 intact:EBI-768015|uniprotkb:Q9ULP2|uniprotkb:B2RDX2|ensembl:ENSP00000304903|ensembl:ENSP00000456935 intact:EBI-536755|uniprotkb:O95109|uniprotkb:Q5VXS5|uniprotkb:Q9H3Z1|uniprotkb:Q9H4T9|uniprotkb:Q9H4U8|uniprotkb:Q9NTE6|ensembl:ENSP00000266079|uniprotkb:B2RAR5|uniprotkb:B3KMC6 psi-mi:cd2b2_human(display_long)|uniprotkb:CD2BP2(gene name)|psi-mi:CD2BP2(display_short)|uniprotkb:KIAA1178(gene name synonym)|uniprotkb:U5 snRNP 52K protein(gene name synonym) psi-mi:prp6_human(display_long)|uniprotkb:U5 snRNP-associated 102 kDa protein(gene name synonym)|uniprotkb:PRP6 homolog(gene name synonym)|uniprotkb:PRPF6(gene name)|psi-mi:PRPF6(display_short)|uniprotkb:C20orf14(gene name synonym)|uniprotkb:Androgen receptor N-terminal domain-transactivating protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Laggerbauer et al. (2005) pubmed:15840814|mint:MINT-5217675 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7595958|mint:MINT-1783290 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230575.1|refseq:NP_006101.1|ensembl:ENSG00000169217(gene)|ensembl:ENST00000305596(transcript)|ensembl:ENST00000569466(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR003169(GYF)|interpro:IPR035445|interpro:IPR039905|mint:O95400|rcsb pdb:1GYF|rcsb pdb:1L2Z|rcsb pdb:1SYX|rcsb pdb:4BWS|reactome:R-HSA-72163|mint:MINT-1783291(identity) ensembl:ENSG00000101161(gene)|ensembl:ENST00000266079(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006403"(RNA localization)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|mint:O94906|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_036601.2|dip:DIP-29006N|mint:MINT-1783301(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5A|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/03/13 2014/10/16 rogid:eE6hXTyt05DhzzofcS/QJmUsLEY9606 rogid:M5ovIXl+1ob6VSKbXZUGU73J7Jk9606 intact-crc:6AD869B29B424054|rigid:Xvc0KOUnslczsrOpxoTagEp89kg false binding-associated region:1-255(MINT-1783292)|tag:?-?(MINT-1783299) tag:?-?(MINT-1783307) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95400 uniprotkb:O94906 intact:EBI-768015|uniprotkb:Q9ULP2|uniprotkb:B2RDX2|ensembl:ENSP00000304903|ensembl:ENSP00000456935 intact:EBI-536755|uniprotkb:O95109|uniprotkb:Q5VXS5|uniprotkb:Q9H3Z1|uniprotkb:Q9H4T9|uniprotkb:Q9H4U8|uniprotkb:Q9NTE6|ensembl:ENSP00000266079|uniprotkb:B2RAR5|uniprotkb:B3KMC6 psi-mi:cd2b2_human(display_long)|uniprotkb:CD2BP2(gene name)|psi-mi:CD2BP2(display_short)|uniprotkb:KIAA1178(gene name synonym)|uniprotkb:U5 snRNP 52K protein(gene name synonym) psi-mi:prp6_human(display_long)|uniprotkb:U5 snRNP-associated 102 kDa protein(gene name synonym)|uniprotkb:PRP6 homolog(gene name synonym)|uniprotkb:PRPF6(gene name)|psi-mi:PRPF6(display_short)|uniprotkb:C20orf14(gene name synonym)|uniprotkb:Androgen receptor N-terminal domain-transactivating protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Laggerbauer et al. (2005) pubmed:15840814|mint:MINT-5217675 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7595987|mint:MINT-1783311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230575.1|refseq:NP_006101.1|ensembl:ENSG00000169217(gene)|ensembl:ENST00000305596(transcript)|ensembl:ENST00000569466(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR003169(GYF)|interpro:IPR035445|interpro:IPR039905|mint:O95400|rcsb pdb:1GYF|rcsb pdb:1L2Z|rcsb pdb:1SYX|rcsb pdb:4BWS|reactome:R-HSA-72163|mint:MINT-1783312(identity) ensembl:ENSG00000101161(gene)|ensembl:ENST00000266079(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006403"(RNA localization)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|mint:O94906|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_036601.2|dip:DIP-29006N|mint:MINT-1783322(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5B|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/13 2014/10/16 rogid:eE6hXTyt05DhzzofcS/QJmUsLEY9606 rogid:M5ovIXl+1ob6VSKbXZUGU73J7Jk9606 intact-crc:1D16FBF173A2367F|rigid:Xvc0KOUnslczsrOpxoTagEp89kg false myc tag:?-?(MINT-1783320)|binding-associated region:1-255(MINT-1783313) glutathione s tranferase tag:?-?(MINT-1783328) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95400 uniprotkb:P83876 intact:EBI-768015|uniprotkb:Q9ULP2|uniprotkb:B2RDX2|ensembl:ENSP00000304903|ensembl:ENSP00000456935 intact:EBI-746539|uniprotkb:O14834|uniprotkb:B2RC18|ensembl:ENSP00000269601 psi-mi:cd2b2_human(display_long)|uniprotkb:CD2BP2(gene name)|psi-mi:CD2BP2(display_short)|uniprotkb:KIAA1178(gene name synonym)|uniprotkb:U5 snRNP 52K protein(gene name synonym) psi-mi:txn4a_human(display_long)|uniprotkb:Thioredoxin-like U5 snRNP protein U5-15kD(gene name synonym)|uniprotkb:Spliceosomal U5 snRNP-specific 15 kDa protein(gene name synonym)|uniprotkb:DIM1 protein homolog(gene name synonym)|uniprotkb:TXNL4A(gene name)|psi-mi:TXNL4A(display_short)|uniprotkb:DIM1(gene name synonym)|uniprotkb:TXNL4(gene name synonym) psi-mi:"MI:0096"(pull down) Laggerbauer et al. (2005) pubmed:15840814|mint:MINT-5217675 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7596008|mint:MINT-1783335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230575.1|refseq:NP_006101.1|ensembl:ENSG00000169217(gene)|ensembl:ENST00000305596(transcript)|ensembl:ENST00000569466(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR003169(GYF)|interpro:IPR035445|interpro:IPR039905|mint:O95400|rcsb pdb:1GYF|rcsb pdb:1L2Z|rcsb pdb:1SYX|rcsb pdb:4BWS|reactome:R-HSA-72163|mint:MINT-1783343(identity) refseq:NP_006692.1|refseq:NP_001290400.1|refseq:NP_001292486.1|refseq:NP_001292492.1|refseq:NP_001292493.1|ensembl:ENSG00000141759(gene)|ensembl:ENST00000269601(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0051301"(cell division)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:1PQN|rcsb pdb:1QGV|rcsb pdb:1SYX|rcsb pdb:3JCR|rcsb pdb:4BWQ|rcsb pdb:4BWS|rcsb pdb:4CDO|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0005682"(U5 snRNP)|mint:MINT-1783336(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5C|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/13 2014/10/16 rogid:eE6hXTyt05DhzzofcS/QJmUsLEY9606 rogid:gGYj9Meks26JpYxw6wB5S2vIrkE9606 intact-crc:D894CB4C4CAC05F7|rigid:DVDcYkBkEz0xSnK7nKeg4nstdVU false binding-associated region:256-341(MINT-1783344)|his tag:?-?(MINT-1783350) ha tag:?-?(MINT-1783341) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)