#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P87061 uniprotkb:O60132 intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep" intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym) psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1100274|imex:IM-19889-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip) ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 - - - comment:Shows that the C-terminal half of tea1 was necessary and sufficient to bind to tea4.|figure legend:Figure 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/09/27 2014/10/16 rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 intact-crc:DB2D803D00DC86AA|rigid:qlHBW+ljlZdXeyOKjdaK/H/Hx7Y false necessary binding region:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60132 uniprotkb:P87061 intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep" psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1100366|imex:IM-19889-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip) - - - comment:The C-terminal third of tea4 mediated the interaction with tea1.|figure legend:Figure 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/09/27 2014/10/16 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812 intact-crc:E163E4E1ED929174|rigid:qlHBW+ljlZdXeyOKjdaK/H/Hx7Y false necessary binding region:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P79065 uniprotkb:P87061 intact:EBI-1102463|ensemblfungi:"SPAC3C7.12.1:pep" intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep" psi-mi:tip1_schpo(display_long)|uniprotkb:tip1(gene name)|psi-mi:tip1(display_short)|uniprotkb:noc1(gene name synonym)|uniprotkb:SPAC3C7.12(orf name)|uniprotkb:Protein noc1(gene name synonym) psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1102456|imex:IM-19889-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|go:"GO:1905759"(post-anaphase array microtubule)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR036859|ensemblfungi:SPAC3C7.12(gene)|ensemblfungi:SPAC3C7.12.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0008017"(microtubule binding)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0071964"(establishment of cell polarity regulating cell shape)|refseq:NP_593613.1|dip:DIP-35371N refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip) - crc64:66CCDB96146F86D6 - comment:The N-terminus of tea1 containing kelch repeats, is necessary for the interaction with tip1.|figure legend:Figure 2E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/09/27 2014/10/16 rogid:7fezraAiuymWvM5MtNZtz0mQzhA284812 rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812 intact-crc:35541F75363A8D2C|rigid:+fpXz7PSMA6RAFDam6mqAvqfgUM false - binding-associated region:72-396(IPR006652) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O94532 uniprotkb:O60132 intact:EBI-1102572|ensemblfungi:"SPCC895.05.1:pep" intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" psi-mi:for3_schpo(display_long)|uniprotkb:for3(gene name)|psi-mi:for3(display_short)|uniprotkb:SPCC895.05(orf name) psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1102557|imex:IM-19889-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPCC895.05(gene)|ensemblfungi:SPCC895.05.1(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0031097"(medial cortex)|go:"GO:0031267"(small GTPase binding)|refseq:NP_588046.1|go:"GO:0032153"(cell division site)|go:"GO:0036391"(medial cortex septin ring)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0061245"(establishment or maintenance of bipolar cell polarity)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1904498"(protein localization to mitotic actomyosin contractile ring)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR042201|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical) ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 - - - figure legend:Figure 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/09/27 2014/10/16 rogid:mApKP2um4XCo0+RW1bsWRJcBj5o284812 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 intact-crc:A1AA705210A079E4|rigid:Jd4i9W7ePtbuyXuYEqagl7L0qAA false necessary binding region:137-515 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60132 uniprotkb:O94532 intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" intact:EBI-1102572|ensemblfungi:"SPCC895.05.1:pep" psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:for3_schpo(display_long)|uniprotkb:for3(gene name)|psi-mi:for3(display_short)|uniprotkb:SPCC895.05(orf name) psi-mi:"MI:0018"(two hybrid) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1102627|imex:IM-19889-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 ensemblfungi:SPCC895.05(gene)|ensemblfungi:SPCC895.05.1(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0031097"(medial cortex)|go:"GO:0031267"(small GTPase binding)|refseq:NP_588046.1|go:"GO:0032153"(cell division site)|go:"GO:0036391"(medial cortex septin ring)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0061245"(establishment or maintenance of bipolar cell polarity)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1904498"(protein localization to mitotic actomyosin contractile ring)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR042201|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical) - - - comment:"No specific domain of tea4p could be defined in for3p binding. Neither the tea4p C-terminal region, which mediates the interaction with tea1p, nor the N-terminal half interacted with for3p reproducibly (Figure 4E), suggesting that multiple parts of the protein may be required for strong interaction. What is clear though is that the SH3 domain of tea4p was dispensable for binding, as shown by deletion or specific point mutation in the SH3 domain."|figure legend:Figure 4E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/09/27 2014/10/16 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 rogid:mApKP2um4XCo0+RW1bsWRJcBj5o284812 intact-crc:BB89D85ABA6725B0|rigid:Jd4i9W7ePtbuyXuYEqagl7L0qAA false - sufficient binding region:1-702 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60132 uniprotkb:P87061 intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep" psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1102108|imex:IM-19889-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip) - - - comment:The tea1-HA coimmunoprecipitation with Tea4-GFP in yeast extracts was determined with an an anti-HA antibody.|figure legend:Figure 1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/09/27 2014/10/16 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812 intact-crc:99F0C9CF8E11769E|rigid:qlHBW+ljlZdXeyOKjdaK/H/Hx7Y false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60132 uniprotkb:P87061 intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep" psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1102183|imex:IM-19889-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip) - - - comment:The tea1-HA coimmunoprecipitation with Tea4-GFP in yeast extracts was determined with an an anti-GFP antibody.|figure legend:Figure 1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/09/27 2014/10/16 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812 intact-crc:F224EF08C0A19DCD|rigid:qlHBW+ljlZdXeyOKjdaK/H/Hx7Y false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P79065 uniprotkb:O60132 intact:EBI-1102463|ensemblfungi:"SPAC3C7.12.1:pep" intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" psi-mi:tip1_schpo(display_long)|uniprotkb:tip1(gene name)|psi-mi:tip1(display_short)|uniprotkb:noc1(gene name synonym)|uniprotkb:SPAC3C7.12(orf name)|uniprotkb:Protein noc1(gene name synonym) psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1104097|imex:IM-19889-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|go:"GO:1905759"(post-anaphase array microtubule)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR036859|ensemblfungi:SPAC3C7.12(gene)|ensemblfungi:SPAC3C7.12.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0008017"(microtubule binding)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0071964"(establishment of cell polarity regulating cell shape)|refseq:NP_593613.1|dip:DIP-35371N ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 - crc64:66CCDB96146F86D6 - comment:Tip1 coimmunoprecipitates with tea4 in a tea1-dependent manner. This experiment was performed using cell extracts from tea1 containing and tea4 depleted cells.|figure legend:Figure 2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/09/27 2014/10/16 rogid:7fezraAiuymWvM5MtNZtz0mQzhA284812 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 intact-crc:046080AD3EF75BFD|rigid:TUC+5GNUwBB8ltNYicLVatCGnFY false - green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P87061 uniprotkb:P79065 intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep" intact:EBI-1102463|ensemblfungi:"SPAC3C7.12.1:pep" psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym) psi-mi:tip1_schpo(display_long)|uniprotkb:tip1(gene name)|psi-mi:tip1(display_short)|uniprotkb:noc1(gene name synonym)|uniprotkb:SPAC3C7.12(orf name)|uniprotkb:Protein noc1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1104111|imex:IM-19889-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip) go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|go:"GO:1905759"(post-anaphase array microtubule)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR036859|ensemblfungi:SPAC3C7.12(gene)|ensemblfungi:SPAC3C7.12.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0008017"(microtubule binding)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0071964"(establishment of cell polarity regulating cell shape)|refseq:NP_593613.1|dip:DIP-35371N - - crc64:66CCDB96146F86D6 comment:Tip1 coimmunoprecipitates with tea1 in a tea4-indedependent manner. This experiment was performed using cell extracts from tea4 containing and tea4 depleted cells.|figure legend:Figure 2G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/09/27 2014/10/16 rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812 rogid:7fezraAiuymWvM5MtNZtz0mQzhA284812 intact-crc:FC5884E5C815F54E|rigid:+fpXz7PSMA6RAFDam6mqAvqfgUM false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O94532 uniprotkb:O60132 intact:EBI-1102572|ensemblfungi:"SPCC895.05.1:pep" intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" psi-mi:for3_schpo(display_long)|uniprotkb:for3(gene name)|psi-mi:for3(display_short)|uniprotkb:SPCC895.05(orf name) psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1104133|imex:IM-19889-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPCC895.05(gene)|ensemblfungi:SPCC895.05.1(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0031097"(medial cortex)|go:"GO:0031267"(small GTPase binding)|refseq:NP_588046.1|go:"GO:0032153"(cell division site)|go:"GO:0036391"(medial cortex septin ring)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0061245"(establishment or maintenance of bipolar cell polarity)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1904498"(protein localization to mitotic actomyosin contractile ring)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR042201|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical) ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 - - - comment:Endogenous tagged for3-HA coimmunoprecipitated with Tea4-GFP in yeast extracts; determined with an an anti-HA and anti-myc antibody. Indicating that tea4p and for3p are present in the same complex in vivo.|figure legend:Figure 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/09/27 2014/10/16 rogid:mApKP2um4XCo0+RW1bsWRJcBj5o284812 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 intact-crc:5E000620F7E39D18|rigid:Jd4i9W7ePtbuyXuYEqagl7L0qAA false myc tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O94532 uniprotkb:O60132 intact:EBI-1102572|ensemblfungi:"SPCC895.05.1:pep" intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" psi-mi:for3_schpo(display_long)|uniprotkb:for3(gene name)|psi-mi:for3(display_short)|uniprotkb:SPCC895.05(orf name) psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1104188|imex:IM-19889-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPCC895.05(gene)|ensemblfungi:SPCC895.05.1(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0031097"(medial cortex)|go:"GO:0031267"(small GTPase binding)|refseq:NP_588046.1|go:"GO:0032153"(cell division site)|go:"GO:0036391"(medial cortex septin ring)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0061245"(establishment or maintenance of bipolar cell polarity)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1904498"(protein localization to mitotic actomyosin contractile ring)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR042201|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical) ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 - - - comment:Endogenous tagged for3-HA interacted with tea1-HA in yeast extracts from tea4-containing cells and not in tea4-depleted cells; determined with an an anti-HA and anti-myc antibody. Indicating that tea4 is required for tea1 and for3 interaction.|figure legend:Figure 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/09/27 2014/10/16 rogid:mApKP2um4XCo0+RW1bsWRJcBj5o284812 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 intact-crc:75F8F3E32F039FEB|rigid:piFiQMAVdIz1SFbUTBXjaEAKBqU false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O94532 uniprotkb:P87061 intact:EBI-1102572|ensemblfungi:"SPCC895.05.1:pep" intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep" psi-mi:for3_schpo(display_long)|uniprotkb:for3(gene name)|psi-mi:for3(display_short)|uniprotkb:SPCC895.05(orf name) psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1104188|imex:IM-19889-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPCC895.05(gene)|ensemblfungi:SPCC895.05.1(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0031097"(medial cortex)|go:"GO:0031267"(small GTPase binding)|refseq:NP_588046.1|go:"GO:0032153"(cell division site)|go:"GO:0036391"(medial cortex septin ring)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0061245"(establishment or maintenance of bipolar cell polarity)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1904498"(protein localization to mitotic actomyosin contractile ring)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR042201|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical) refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip) - - - comment:Endogenous tagged for3-HA interacted with tea1-HA in yeast extracts from tea4-containing cells and not in tea4-depleted cells; determined with an an anti-HA and anti-myc antibody. Indicating that tea4 is required for tea1 and for3 interaction.|figure legend:Figure 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/09/27 2014/10/16 rogid:mApKP2um4XCo0+RW1bsWRJcBj5o284812 rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812 intact-crc:75F8F3E32F039FEB|rigid:piFiQMAVdIz1SFbUTBXjaEAKBqU false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60132 uniprotkb:P87061 intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep" psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym) psi-mi:"MI:0096"(pull down) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1102422|imex:IM-19889-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip) - - - comment:Bacterially expressed tea1-MBP bound to tea4-His in in-vitro pull-down experiment.|figure legend:Figure 1F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/27 2014/10/16 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812 intact-crc:400B26DFD2118F06|rigid:qlHBW+ljlZdXeyOKjdaK/H/Hx7Y false his tag:?-? maltose binding protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P87061 uniprotkb:P87061 intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep" intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep" psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym) psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym) psi-mi:"MI:0096"(pull down) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1102435|imex:IM-19889-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip) refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip) - - - comment:Bacterially expressed tea1-MBP bound to tea1-His in in-vitro pull-down experiment as shown in Figures 1F and 4B.|figure legend:Figure 1F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/27 2014/10/16 rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812 rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812 intact-crc:ED5C33538A3D237F|rigid:HRbvb9iMRqDXeXxQLndGYGKzKco false binding-associated region:?-?|his tag:?-? binding-associated region:?-?|maltose binding protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O60132 uniprotkb:P87061 intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep" psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym) psi-mi:"MI:0096"(pull down) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1104249|imex:IM-19889-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip) - - - comment:Bacterially expressed tea1-His bound to tea4-MBP in in-vitro pull-down experiment.|figure legend:Figure 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/27 2014/10/16 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812 intact-crc:6D6D54909EA90A77|rigid:qlHBW+ljlZdXeyOKjdaK/H/Hx7Y false maltose binding protein tag:?-? binding-associated region:?-?|his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O94532 uniprotkb:O60132 intact:EBI-1102572|ensemblfungi:"SPCC895.05.1:pep" intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" psi-mi:for3_schpo(display_long)|uniprotkb:for3(gene name)|psi-mi:for3(display_short)|uniprotkb:SPCC895.05(orf name) psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:"MI:0096"(pull down) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1104275|imex:IM-19889-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPCC895.05(gene)|ensemblfungi:SPCC895.05.1(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0031097"(medial cortex)|go:"GO:0031267"(small GTPase binding)|refseq:NP_588046.1|go:"GO:0032153"(cell division site)|go:"GO:0036391"(medial cortex septin ring)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0061245"(establishment or maintenance of bipolar cell polarity)|go:"GO:0061572"(actin filament bundle organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1904498"(protein localization to mitotic actomyosin contractile ring)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR042201|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical) ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 - - - comment:Bacterially expressed N-terminus for3-His bound to tea4-MBP in an in-vitro pull-down experiment.|figure legend:Figure 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/27 2014/10/16 rogid:mApKP2um4XCo0+RW1bsWRJcBj5o284812 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 intact-crc:38205D52C45127FA|rigid:Jd4i9W7ePtbuyXuYEqagl7L0qAA false binding-associated region:1-702|his tag:?-? maltose binding protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O60132 uniprotkb:P87061 intact:EBI-1099982|ensemblfungi:"SPBC1706.01.1:pep" intact:EBI-875376|ensemblfungi:"SPCC1223.06.1:pep" psi-mi:tea4_schpo(display_long)|uniprotkb:SPBC1706.01(orf name)|uniprotkb:tea4(gene name)|psi-mi:tea4(display_short)|uniprotkb:wsh3(gene name synonym)|uniprotkb:Cell polarity protein tea4(gene name synonym)|uniprotkb:Win1-interacting SH3 domain protein(gene name synonym) psi-mi:tea1_schpo(display_long)|uniprotkb:Cell polarity protein tea1(gene name synonym)|uniprotkb:Altered polarity protein 8(gene name synonym)|uniprotkb:tea1(gene name)|psi-mi:tea1(display_short)|uniprotkb:SPCC1223.06(orf name)|uniprotkb:alp8(gene name synonym) psi-mi:"MI:0399"(two hybrid fragment pooling approach) Martin et al. (2005) pubmed:15809031|imex:IM-19889 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1104228|imex:IM-19889-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPBC1706.01(gene)|ensemblfungi:SPBC1706.01.1(transcript)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051523"(cell growth mode switching, monopolar to bipolar)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097248"(maintenance of protein location in cell cortex of cell tip)|go:"GO:0097575"(lateral cell cortex)|go:"GO:1902486"(protein localization to growing cell tip)|go:"GO:1903067"(negative regulation of protein localization to cell tip)|go:"GO:1903068"(positive regulation of protein localization to cell tip)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|interpro:IPR001452(Src homology-3)|refseq:NP_595240.2|interpro:IPR036028 refseq:NP_588351.1|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|ensemblfungi:SPCC1223.06(gene)|ensemblfungi:SPCC1223.06.1(transcript)|go:"GO:0000935"(division septum)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032153"(cell division site)|go:"GO:0035838"(growing cell tip)|go:"GO:0035839"(non-growing cell tip)|go:"GO:0035840"(old growing cell tip)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099070"(static microtubule bundle)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|go:"GO:1990896"(protein localization to cell cortex of cell tip) go:"GO:0005874"(microtubule)|go:"GO:0051286"(cell tip) - - comment:Tea4-YFP colocalizes precisely with tea1-CFP in vivo.|figure legend:Figure 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/09/27 2014/10/16 rogid:qSXLZ7v598SNQaVW2IeVIGT8O+0284812 rogid:++hYTqk6duih7aGYqCPKY6k3ZYM284812 intact-crc:59D9C6FA5FE04BC4|rigid:qlHBW+ljlZdXeyOKjdaK/H/Hx7Y false yellow fluorescent protein tag:?-? cyan fluorescent protein tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)