#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P02795 uniprotkb:Q8TE69 intact:EBI-996616|uniprotkb:Q2HXR9|uniprotkb:Q53XT9|uniprotkb:Q14823|ensembl:ENSP00000245185 intact:EBI-996609|uniprotkb:Q2M3E9|uniprotkb:A0A0A0MTB5|uniprotkb:A8K784|uniprotkb:B7ZL96|ensembl:ENSP00000420882|ensembl:ENSP00000421745|ensembl:ENSP00000422512|ensembl:ENSP00000423099|ensembl:ENSP00000425520|ensembl:ENSP00000427540|uniprotkb:B7Z6H6|uniprotkb:D6RA72|uniprotkb:E7ENU3 psi-mi:mt2_human(display_long)|uniprotkb:Metallothionein-II(gene name synonym)|uniprotkb:Metallothionein-2A(gene name synonym)|uniprotkb:MT2A(gene name)|psi-mi:MT2A(display_short)|uniprotkb:CES1(gene name synonym)|uniprotkb:MT2(gene name synonym) psi-mi:eola1_human(display_long)|uniprotkb:EOLA1(gene name)|psi-mi:EOLA1(display_short)|uniprotkb:CXorf40(gene name synonym)|uniprotkb:CXorf40A(gene name synonym)|uniprotkb:Endothelial-overexpressed lipopolysaccharide-associated factor 1(gene name synonym)|uniprotkb:Endothelium and lymphocyte associated ASCH domain 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Liang et al. (2004) pubmed:15541360|imex:IM-18977 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-996630|imex:IM-18977-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005944.1|ensembl:ENSG00000125148(gene)|ensembl:ENST00000245185(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0036018"(cellular response to erythropoietin)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071294"(cellular response to zinc ion)|interpro:IPR000006(Metallothionein, vertebrate)|interpro:IPR003019(Metallothionein superfamily, eukaryotic)|interpro:IPR017854(Metallothionein superfamily)|interpro:IPR018064|interpro:IPR023587|mint:P02795|rcsb pdb:1MHU|rcsb pdb:2MHU|go:"GO:0006882"(cellular zinc ion homeostasis)|reactome:R-HSA-877300|reactome:R-HSA-5661231|dip:DIP-35232N refseq:NP_001165378.1|refseq:NP_001165379.1|refseq:NP_835225.2|refseq:NP_001165380.1|refseq:NP_001311205.1|refseq:NP_001311208.1|refseq:NP_001311203.1|refseq:NP_001311204.1|refseq:NP_001311206.1|refseq:NP_001311207.1|refseq:NP_001311209.1|ensembl:ENSG00000197620(gene)|ensembl:ENST00000359293(transcript)|ensembl:ENST00000393985(transcript)|ensembl:ENST00000423421(transcript)|ensembl:ENST00000423540(transcript)|ensembl:ENST00000441248(transcript)|ensembl:ENST00000450602(transcript)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR015947(PUA-like)|go:"GO:0032675"(regulation of interleukin-6 production)|interpro:IPR007374(Protein of unknown function DUF437)|interpro:IPR033615|rcsb pdb:5Y7D|refseq:XP_005262406.2 - - - figure legend:None|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/08/23 2018/04/06 rogid:3adUmT5As6Rn1isYoH+jMsFKEgU9606 rogid:iPxvTiZGOxEoQw0r2TlKHL0J0bw9606 intact-crc:1936435D85C11D34|rigid:EYf/W1+nG7Pq+fnxlm82ejsfqS0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02795 uniprotkb:Q8TE69 intact:EBI-996616|uniprotkb:Q2HXR9|uniprotkb:Q53XT9|uniprotkb:Q14823|ensembl:ENSP00000245185 intact:EBI-996609|uniprotkb:Q2M3E9|uniprotkb:A0A0A0MTB5|uniprotkb:A8K784|uniprotkb:B7ZL96|ensembl:ENSP00000420882|ensembl:ENSP00000421745|ensembl:ENSP00000422512|ensembl:ENSP00000423099|ensembl:ENSP00000425520|ensembl:ENSP00000427540|uniprotkb:B7Z6H6|uniprotkb:D6RA72|uniprotkb:E7ENU3 psi-mi:mt2_human(display_long)|uniprotkb:Metallothionein-II(gene name synonym)|uniprotkb:Metallothionein-2A(gene name synonym)|uniprotkb:MT2A(gene name)|psi-mi:MT2A(display_short)|uniprotkb:CES1(gene name synonym)|uniprotkb:MT2(gene name synonym) psi-mi:eola1_human(display_long)|uniprotkb:EOLA1(gene name)|psi-mi:EOLA1(display_short)|uniprotkb:CXorf40(gene name synonym)|uniprotkb:CXorf40A(gene name synonym)|uniprotkb:Endothelial-overexpressed lipopolysaccharide-associated factor 1(gene name synonym)|uniprotkb:Endothelium and lymphocyte associated ASCH domain 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liang et al. (2004) pubmed:15541360|imex:IM-18977 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-996641|imex:IM-18977-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005944.1|ensembl:ENSG00000125148(gene)|ensembl:ENST00000245185(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0036018"(cellular response to erythropoietin)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071294"(cellular response to zinc ion)|interpro:IPR000006(Metallothionein, vertebrate)|interpro:IPR003019(Metallothionein superfamily, eukaryotic)|interpro:IPR017854(Metallothionein superfamily)|interpro:IPR018064|interpro:IPR023587|mint:P02795|rcsb pdb:1MHU|rcsb pdb:2MHU|go:"GO:0006882"(cellular zinc ion homeostasis)|reactome:R-HSA-877300|reactome:R-HSA-5661231|dip:DIP-35232N refseq:NP_001165378.1|refseq:NP_001165379.1|refseq:NP_835225.2|refseq:NP_001165380.1|refseq:NP_001311205.1|refseq:NP_001311208.1|refseq:NP_001311203.1|refseq:NP_001311204.1|refseq:NP_001311206.1|refseq:NP_001311207.1|refseq:NP_001311209.1|ensembl:ENSG00000197620(gene)|ensembl:ENST00000359293(transcript)|ensembl:ENST00000393985(transcript)|ensembl:ENST00000423421(transcript)|ensembl:ENST00000423540(transcript)|ensembl:ENST00000441248(transcript)|ensembl:ENST00000450602(transcript)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR015947(PUA-like)|go:"GO:0032675"(regulation of interleukin-6 production)|interpro:IPR007374(Protein of unknown function DUF437)|interpro:IPR033615|rcsb pdb:5Y7D|refseq:XP_005262406.2 - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ecv304)|taxid:9606(Human umbilical cord, endothelial ECV304) - 2006/08/23 2018/04/06 rogid:3adUmT5As6Rn1isYoH+jMsFKEgU9606 rogid:iPxvTiZGOxEoQw0r2TlKHL0J0bw9606 intact-crc:118BCFAD21BCFB45|rigid:EYf/W1+nG7Pq+fnxlm82ejsfqS0 false - enhanced green fluorescent protein tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)