#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P14649 uniprotkb:Q02440 intact:EBI-358570|ensembl:ENSP00000446643|ensembl:ENSP00000450385 intact:EBI-1040586 psi-mi:myl6b_human(display_long)|uniprotkb:MYL6B(gene name)|psi-mi:MYL6B(display_short)|uniprotkb:MLC1SA(gene name synonym)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6B(gene name synonym)|uniprotkb:Myosin light chain 1 slow-twitch muscle A isoform(gene name synonym) psi-mi:myo5a_chick(display_long)|uniprotkb:MYO5A(gene name)|psi-mi:MYO5A(display_short)|uniprotkb:Dilute myosin heavy chain, non-muscle(gene name synonym)|uniprotkb:Myosin heavy chain p190(gene name synonym)|uniprotkb:Myosin-V(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Coureux et al. (2004) pubmed:15510214 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1040601|rcsb pdb:1W7I - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186558.1|refseq:NP_002466.1|ensembl:ENSG00000196465(gene)|ensembl:ENST00000550443(transcript)|ensembl:ENST00000553066(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1OE9|rcsb pdb:1W7I|rcsb pdb:1W7J|reactome:R-HSA-445355 refseq:NP_990631.1|interpro:IPR002710(Dilute)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|rcsb pdb:1OE9|rcsb pdb:1W7I|rcsb pdb:1W7J|rcsb pdb:1W8J|rcsb pdb:2DFS|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0000139"(Golgi membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0051015"(actin filament binding)|go:"GO:0060001"(minus-end directed microfilament motor activity)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR027417|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR037988|interpro:IPR036103 - - - assembly:dimeric, multimeric|3d-r-factors:working 75.200%, free 68.200%|3d-resolution:3A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:S0/S5hUxfyyve1JDMojIggOSBb89606 rogid:EIUZG+K7PN9GYhlS/4S098lZALg9031 intact-crc:8E2732535BA2B2AB|rigid:7gItJ4yWq2nS/gR0FQOiBEilGbM false sufficient binding region:59-208 sufficient binding region:1-792 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02440 uniprotkb:P14649 intact:EBI-1040586 intact:EBI-358570|ensembl:ENSP00000446643|ensembl:ENSP00000450385 psi-mi:myo5a_chick(display_long)|uniprotkb:MYO5A(gene name)|psi-mi:MYO5A(display_short)|uniprotkb:Dilute myosin heavy chain, non-muscle(gene name synonym)|uniprotkb:Myosin heavy chain p190(gene name synonym)|uniprotkb:Myosin-V(gene name synonym) psi-mi:myl6b_human(display_long)|uniprotkb:MYL6B(gene name)|psi-mi:MYL6B(display_short)|uniprotkb:MLC1SA(gene name synonym)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6B(gene name synonym)|uniprotkb:Myosin light chain 1 slow-twitch muscle A isoform(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Coureux et al. (2004) pubmed:15510214 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1040612|rcsb pdb:1W7J - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_990631.1|interpro:IPR002710(Dilute)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|rcsb pdb:1OE9|rcsb pdb:1W7I|rcsb pdb:1W7J|rcsb pdb:1W8J|rcsb pdb:2DFS|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0000139"(Golgi membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0051015"(actin filament binding)|go:"GO:0060001"(minus-end directed microfilament motor activity)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR027417|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR037988|interpro:IPR036103 refseq:NP_001186558.1|refseq:NP_002466.1|ensembl:ENSG00000196465(gene)|ensembl:ENST00000550443(transcript)|ensembl:ENST00000553066(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1OE9|rcsb pdb:1W7I|rcsb pdb:1W7J|reactome:R-HSA-445355 - - - assembly:tetrameric, multimeric|3d-r-factors:working 80.600%, free 77.600%|3d-resolution:2A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:EIUZG+K7PN9GYhlS/4S098lZALg9031 rogid:S0/S5hUxfyyve1JDMojIggOSBb89606 intact-crc:104AE2E0F499E4C0|rigid:7gItJ4yWq2nS/gR0FQOiBEilGbM false sufficient binding region:1-792 sufficient binding region:59-208 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)