#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P28065 uniprotkb:Q2M3G0 intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027 intact:EBI-780706|uniprotkb:B5MD19|uniprotkb:A4D131|uniprotkb:Q2M3I5|uniprotkb:Q5I5Q7|uniprotkb:Q5I5Q8|uniprotkb:Q6KG50|uniprotkb:Q6XFQ5|uniprotkb:Q8IXA1|uniprotkb:B7WPL1|uniprotkb:F8QQP8|uniprotkb:F8QQP9|uniprotkb:A7BKA4|uniprotkb:J3KQ04|ensembl:ENSP00000384881 psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym) psi-mi:abcb5_human(display_long)|uniprotkb:ABCB5(gene name)|psi-mi:ABCB5(display_short)|uniprotkb:P-glycoprotein ABCB5(gene name synonym)|uniprotkb:ABCB5 P-gp(gene name synonym) psi-mi:"MI:0018"(two hybrid) Begley et al. (2005) pubmed:15488952 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-780721 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 refseq:NP_001157413.1|refseq:NP_848654.3|refseq:NP_001157414.1|refseq:XP_011513669.1|refseq:NP_001157465.1|ensembl:ENSG00000004846(gene)|ensembl:ENST00000404938(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|reactome:R-HSA-382556 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/01/10 2014/10/16 rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606 rogid:zYirl24vXctqZ/bE8rXB0MFJows9606 intact-crc:A7D82B086A68824C|rigid:ZHDFWU++DYbNL+G+k/KbAxOKF6M false - binding-associated region:792-1154 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28065 uniprotkb:Q03518 intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027 intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660 psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym) psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Begley et al. (2005) pubmed:15488952 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-780756 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/01/10 2014/10/16 rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606 rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606 intact-crc:E810CB02C2E03D4D|rigid:VAsWk3zqv1lGhTNY1Z6nX9zJthU false - binding-associated region:480-748 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03518 uniprotkb:P28062 intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660 intact:EBI-372294|uniprotkb:Q29824|uniprotkb:Q96J48|uniprotkb:Q5JNW6|uniprotkb:B0UZC0|ensembl:ENSP00000364016|ensembl:ENSP00000372723|ensembl:ENSP00000394155|ensembl:ENSP00000402406|ensembl:ENSP00000404585|ensembl:ENSP00000406797|ensembl:ENSP00000414770|intact:EBI-780761|uniprotkb:Q5QNR8 psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym) psi-mi:psb8_human(display_long)|uniprotkb:PSMB8(gene name)|psi-mi:PSMB8(display_short)|uniprotkb:LMP7(gene name synonym)|uniprotkb:RING10(gene name synonym)|uniprotkb:Y2(gene name synonym)|uniprotkb:Proteasome subunit beta-5i(gene name synonym)|uniprotkb:Proteasome component C13(gene name synonym)|uniprotkb:Macropain subunit C13(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C13(gene name synonym)|uniprotkb:Low molecular mass protein 7(gene name synonym)|uniprotkb:PSMB5i(gene name synonym)|uniprotkb:Really interesting new gene 10 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Begley et al. (2005) pubmed:15488952 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-780775 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5L5B|ensembl:ENSG00000204264(gene)|ensembl:ENSG00000206298(gene)|ensembl:ENSG00000226201(gene)|ensembl:ENSG00000230669(gene)|ensembl:ENSG00000231631(gene)|ensembl:ENSG00000235715(gene)|ensembl:ENSG00000236443(gene)|ensembl:ENST00000374882(transcript)|ensembl:ENST00000383236(transcript)|ensembl:ENST00000421445(transcript)|ensembl:ENST00000429645(transcript)|ensembl:ENST00000438442(transcript)|ensembl:ENST00000455660(transcript)|ensembl:ENST00000457261(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035705|rcsb pdb:5L5A|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-174178|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-909733|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5687128|refseq:NP_004150.1|refseq:NP_683720.2 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/01/10 2014/10/16 rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606 rogid:XSNs073UKpjwL4TejKS9mczVX9I9606 intact-crc:7D0B4FCEC32AA230|rigid:xzAmsg+dpYQaFblqj7rE3kLGbRw false binding-associated region:480-748 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03519 uniprotkb:P28062 intact:EBI-780781|uniprotkb:Q9UQ83|uniprotkb:O95410|uniprotkb:B0V2J8|uniprotkb:Q53FI6|uniprotkb:Q5HY71|uniprotkb:Q96PT8|ensembl:ENSP00000364032|ensembl:ENSP00000372599|ensembl:ENSP00000372726|ensembl:ENSP00000390013|ensembl:ENSP00000394101 intact:EBI-372294|uniprotkb:Q29824|uniprotkb:Q96J48|uniprotkb:Q5JNW6|uniprotkb:B0UZC0|ensembl:ENSP00000364016|ensembl:ENSP00000372723|ensembl:ENSP00000394155|ensembl:ENSP00000402406|ensembl:ENSP00000404585|ensembl:ENSP00000406797|ensembl:ENSP00000414770|intact:EBI-780761|uniprotkb:Q5QNR8 psi-mi:tap2_human(display_long)|uniprotkb:ATP-binding cassette sub-family B member 3(gene name synonym)|uniprotkb:Peptide transporter TAP2(gene name synonym)|uniprotkb:Peptide supply factor 2(gene name synonym)|uniprotkb:Peptide transporter PSF2(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 2(gene name synonym)|uniprotkb:TAP2(gene name)|psi-mi:TAP2(display_short)|uniprotkb:ABCB3(gene name synonym)|uniprotkb:PSF2(gene name synonym)|uniprotkb:RING11(gene name synonym)|uniprotkb:Y1(gene name synonym)|uniprotkb:Really interesting new gene 11 protein(gene name synonym) psi-mi:psb8_human(display_long)|uniprotkb:PSMB8(gene name)|psi-mi:PSMB8(display_short)|uniprotkb:LMP7(gene name synonym)|uniprotkb:RING10(gene name synonym)|uniprotkb:Y2(gene name synonym)|uniprotkb:Proteasome subunit beta-5i(gene name synonym)|uniprotkb:Proteasome component C13(gene name synonym)|uniprotkb:Macropain subunit C13(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C13(gene name synonym)|uniprotkb:Low molecular mass protein 7(gene name synonym)|uniprotkb:PSMB5i(gene name synonym)|uniprotkb:Really interesting new gene 10 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Begley et al. (2005) pubmed:15488952 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-780813 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276972.1|refseq:NP_000535.3|refseq:NP_061313.2|dip:DIP-322N|ensembl:ENSG00000204267(gene)|ensembl:ENSG00000206235(gene)|ensembl:ENSG00000206299(gene)|ensembl:ENSG00000228582(gene)|ensembl:ENSG00000237599(gene)|ensembl:ENST00000374897(transcript)|ensembl:ENST00000383118(transcript)|ensembl:ENST00000383239(transcript)|ensembl:ENST00000419142(transcript)|ensembl:ENST00000443713(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002489"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046968"(peptide antigen transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046980"(tapasin binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005293(Antigen peptide transporter 2)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03519|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170 rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5L5B|ensembl:ENSG00000204264(gene)|ensembl:ENSG00000206298(gene)|ensembl:ENSG00000226201(gene)|ensembl:ENSG00000230669(gene)|ensembl:ENSG00000231631(gene)|ensembl:ENSG00000235715(gene)|ensembl:ENSG00000236443(gene)|ensembl:ENST00000374882(transcript)|ensembl:ENST00000383236(transcript)|ensembl:ENST00000421445(transcript)|ensembl:ENST00000429645(transcript)|ensembl:ENST00000438442(transcript)|ensembl:ENST00000455660(transcript)|ensembl:ENST00000457261(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035705|rcsb pdb:5L5A|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-174178|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-909733|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5687128|refseq:NP_004150.1|refseq:NP_683720.2 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/01/10 2014/10/16 rogid:w7pDqjoSODoB8qMag1ycxcapvQ09606 rogid:XSNs073UKpjwL4TejKS9mczVX9I9606 intact-crc:2D026982D1EF764E|rigid:af0jUabh2uk2NdS8hblT4fB+vLE false binding-associated region:471-686 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28065 uniprotkb:Q03519 intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027 intact:EBI-780781|uniprotkb:Q9UQ83|uniprotkb:O95410|uniprotkb:B0V2J8|uniprotkb:Q53FI6|uniprotkb:Q5HY71|uniprotkb:Q96PT8|ensembl:ENSP00000364032|ensembl:ENSP00000372599|ensembl:ENSP00000372726|ensembl:ENSP00000390013|ensembl:ENSP00000394101 psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym) psi-mi:tap2_human(display_long)|uniprotkb:ATP-binding cassette sub-family B member 3(gene name synonym)|uniprotkb:Peptide transporter TAP2(gene name synonym)|uniprotkb:Peptide supply factor 2(gene name synonym)|uniprotkb:Peptide transporter PSF2(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 2(gene name synonym)|uniprotkb:TAP2(gene name)|psi-mi:TAP2(display_short)|uniprotkb:ABCB3(gene name synonym)|uniprotkb:PSF2(gene name synonym)|uniprotkb:RING11(gene name synonym)|uniprotkb:Y1(gene name synonym)|uniprotkb:Really interesting new gene 11 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Begley et al. (2005) pubmed:15488952 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-780819 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 refseq:NP_001276972.1|refseq:NP_000535.3|refseq:NP_061313.2|dip:DIP-322N|ensembl:ENSG00000204267(gene)|ensembl:ENSG00000206235(gene)|ensembl:ENSG00000206299(gene)|ensembl:ENSG00000228582(gene)|ensembl:ENSG00000237599(gene)|ensembl:ENST00000374897(transcript)|ensembl:ENST00000383118(transcript)|ensembl:ENST00000383239(transcript)|ensembl:ENST00000419142(transcript)|ensembl:ENST00000443713(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002489"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046968"(peptide antigen transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046980"(tapasin binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005293(Antigen peptide transporter 2)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03519|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/01/10 2014/10/16 rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606 rogid:w7pDqjoSODoB8qMag1ycxcapvQ09606 intact-crc:B819ED4ED025E933|rigid:RVOL7O11ibZtFjsJqrSFhEJc9zg false - binding-associated region:471-686 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28065 uniprotkb:Q2M3G0 intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027 intact:EBI-780706|uniprotkb:B5MD19|uniprotkb:A4D131|uniprotkb:Q2M3I5|uniprotkb:Q5I5Q7|uniprotkb:Q5I5Q8|uniprotkb:Q6KG50|uniprotkb:Q6XFQ5|uniprotkb:Q8IXA1|uniprotkb:B7WPL1|uniprotkb:F8QQP8|uniprotkb:F8QQP9|uniprotkb:A7BKA4|uniprotkb:J3KQ04|ensembl:ENSP00000384881 psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym) psi-mi:abcb5_human(display_long)|uniprotkb:ABCB5(gene name)|psi-mi:ABCB5(display_short)|uniprotkb:P-glycoprotein ABCB5(gene name synonym)|uniprotkb:ABCB5 P-gp(gene name synonym) psi-mi:"MI:0018"(two hybrid) Begley et al. (2005) pubmed:15488952 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-780825 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 refseq:NP_001157413.1|refseq:NP_848654.3|refseq:NP_001157414.1|refseq:XP_011513669.1|refseq:NP_001157465.1|ensembl:ENSG00000004846(gene)|ensembl:ENST00000404938(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|reactome:R-HSA-382556 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/01/10 2014/10/16 rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606 rogid:zYirl24vXctqZ/bE8rXB0MFJows9606 intact-crc:FB2BE5804E7F3998|rigid:ZHDFWU++DYbNL+G+k/KbAxOKF6M false - binding-associated region:792-1154 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03518 uniprotkb:P28062 intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660 intact:EBI-372294|uniprotkb:Q29824|uniprotkb:Q96J48|uniprotkb:Q5JNW6|uniprotkb:B0UZC0|ensembl:ENSP00000364016|ensembl:ENSP00000372723|ensembl:ENSP00000394155|ensembl:ENSP00000402406|ensembl:ENSP00000404585|ensembl:ENSP00000406797|ensembl:ENSP00000414770|intact:EBI-780761|uniprotkb:Q5QNR8 psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym) psi-mi:psb8_human(display_long)|uniprotkb:PSMB8(gene name)|psi-mi:PSMB8(display_short)|uniprotkb:LMP7(gene name synonym)|uniprotkb:RING10(gene name synonym)|uniprotkb:Y2(gene name synonym)|uniprotkb:Proteasome subunit beta-5i(gene name synonym)|uniprotkb:Proteasome component C13(gene name synonym)|uniprotkb:Macropain subunit C13(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C13(gene name synonym)|uniprotkb:Low molecular mass protein 7(gene name synonym)|uniprotkb:PSMB5i(gene name synonym)|uniprotkb:Really interesting new gene 10 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Begley et al. (2005) pubmed:15488952 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-780830 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5L5B|ensembl:ENSG00000204264(gene)|ensembl:ENSG00000206298(gene)|ensembl:ENSG00000226201(gene)|ensembl:ENSG00000230669(gene)|ensembl:ENSG00000231631(gene)|ensembl:ENSG00000235715(gene)|ensembl:ENSG00000236443(gene)|ensembl:ENST00000374882(transcript)|ensembl:ENST00000383236(transcript)|ensembl:ENST00000421445(transcript)|ensembl:ENST00000429645(transcript)|ensembl:ENST00000438442(transcript)|ensembl:ENST00000455660(transcript)|ensembl:ENST00000457261(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035705|rcsb pdb:5L5A|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-174178|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-909733|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5687128|refseq:NP_004150.1|refseq:NP_683720.2 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/01/10 2014/10/16 rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606 rogid:XSNs073UKpjwL4TejKS9mczVX9I9606 intact-crc:21F88146E73D19E4|rigid:xzAmsg+dpYQaFblqj7rE3kLGbRw false binding-associated region:480-748 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03518 uniprotkb:P28065 intact:EBI-747259|uniprotkb:Q16149|intact:EBI-780739|uniprotkb:Q96CP4|ensembl:ENSP00000346206|ensembl:ENSP00000372722|ensembl:ENSP00000401149|ensembl:ENSP00000402316|ensembl:ENSP00000405356|ensembl:ENSP00000413080|ensembl:ENSP00000415660 intact:EBI-603300|uniprotkb:Q16523|uniprotkb:B0V0T1|intact:EBI-780725|uniprotkb:Q5JNW4|ensembl:ENSP00000363993|ensembl:ENSP00000372595|ensembl:ENSP00000372721|ensembl:ENSP00000393744|ensembl:ENSP00000396813|ensembl:ENSP00000407233|ensembl:ENSP00000407810|ensembl:ENSP00000412027 psi-mi:tap1_human(display_long)|uniprotkb:ABCB2(gene name synonym)|uniprotkb:PSF1(gene name synonym)|uniprotkb:RING4(gene name synonym)|uniprotkb:Y3(gene name synonym)|uniprotkb:TAP1(gene name)|psi-mi:TAP1(display_short)|uniprotkb:Peptide transporter TAP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 2(gene name synonym)|uniprotkb:Peptide supply factor 1(gene name synonym)|uniprotkb:Peptide transporter PSF1(gene name synonym)|uniprotkb:Peptide transporter involved in antigen processing 1(gene name synonym)|uniprotkb:Really interesting new gene 4 protein(gene name synonym) psi-mi:psb9_human(display_long)|uniprotkb:PSMB9(gene name)|psi-mi:PSMB9(display_short)|uniprotkb:LMP2(gene name synonym)|uniprotkb:RING12(gene name synonym)|uniprotkb:Proteasome subunit beta-1i(gene name synonym)|uniprotkb:Proteasome chain 7(gene name synonym)|uniprotkb:Macropain chain 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain 7(gene name synonym)|uniprotkb:Really interesting new gene 12 protein(gene name synonym)|uniprotkb:Low molecular mass protein 2(gene name synonym)|uniprotkb:PSMB6i(gene name synonym) psi-mi:"MI:0018"(two hybrid) Begley et al. (2005) pubmed:15488952 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-780835 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000584.2|refseq:NP_001278951.1|ensembl:ENSG00000168394(gene)|ensembl:ENSG00000206297(gene)|ensembl:ENSG00000224212(gene)|ensembl:ENSG00000226173(gene)|ensembl:ENSG00000227816(gene)|ensembl:ENSG00000230705(gene)|ensembl:ENSG00000232367(gene)|ensembl:ENST00000354258(transcript)|ensembl:ENST00000383235(transcript)|ensembl:ENST00000414467(transcript)|ensembl:ENST00000418205(transcript)|ensembl:ENST00000424897(transcript)|ensembl:ENST00000439781(transcript)|ensembl:ENST00000440894(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR013306(ABC transporter, B3)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:Q03518|rcsb pdb:1JJ7|rcsb pdb:5U1D|reactome:R-HSA-1236974|reactome:R-HSA-983170|dip:DIP-35626N refseq:NP_002791.1|ensembl:ENSG00000239836(gene)|ensembl:ENSG00000240065(gene)|ensembl:ENSG00000240118(gene)|ensembl:ENSG00000240508(gene)|ensembl:ENSG00000242711(gene)|ensembl:ENSG00000243067(gene)|ensembl:ENSG00000243594(gene)|ensembl:ENSG00000243958(gene)|ensembl:ENST00000374859(transcript)|ensembl:ENST00000383114(transcript)|ensembl:ENST00000383234(transcript)|ensembl:ENST00000422729(transcript)|ensembl:ENST00000427870(transcript)|ensembl:ENST00000434471(transcript)|ensembl:ENST00000444284(transcript)|ensembl:ENST00000453059(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR034383|mint:P28065|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/01/10 2014/10/16 rogid:fkl1VU1VSl8sEjURg8kRj0joZlY9606 rogid:lvkgxYAFbxVvTsPkbtI+8PS48ko9606 intact-crc:B4E3058AE6F78699|rigid:VAsWk3zqv1lGhTNY1Z6nX9zJthU false binding-associated region:480-748 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)