#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13523	uniprotkb:P04590	intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547	intact:EBI-780156	psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym)	psi-mi:gag_hv2ro(display_long)|uniprotkb:Pr55Gag(gene name synonym)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2004)	pubmed:15452250	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11720(hv2ro)|taxid:11720("Human immunodeficiency virus type 2 subtype A (isolate ROD) (HIV-2)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-780166	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1	rcsb pdb:4DGB|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|rcsb pdb:2WLV|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR036875|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/01/10	2014/10/16	rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606	rogid:6l9T24/AOWtOk6d9Whne4zAef4g11720	intact-crc:FB6BB65E9287C3BE|rigid:5H85cYY2PaFCxrFuMQEr4NdrmUg	false	sufficient binding region:512-1007	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P68104	uniprotkb:P04590	intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274	intact:EBI-780156	psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym)	psi-mi:gag_hv2ro(display_long)|uniprotkb:Pr55Gag(gene name synonym)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2004)	pubmed:15452250	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11720(hv2ro)|taxid:11720("Human immunodeficiency virus type 2 subtype A (isolate ROD) (HIV-2)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-780171	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1	rcsb pdb:4DGB|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|rcsb pdb:2WLV|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR036875|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/01/10	2014/10/16	rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606	rogid:6l9T24/AOWtOk6d9Whne4zAef4g11720	intact-crc:F5AD663E7C7BCD0F|rigid:uGdeW4lzxRWdH0pE3GINa2ePozQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04590	uniprotkb:Q99816	intact:EBI-780156	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	psi-mi:gag_hv2ro(display_long)|uniprotkb:Pr55Gag(gene name synonym)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bennett et al. (2004)	pubmed:15452250	taxid:11720(hv2ro)|taxid:11720("Human immunodeficiency virus type 2 subtype A (isolate ROD) (HIV-2)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-780181	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4DGB|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|rcsb pdb:2WLV|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR036875|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/01/10	2014/10/16	rogid:6l9T24/AOWtOk6d9Whne4zAef4g11720	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	intact-crc:59D647FEE3488404|rigid:bDsgMOgFJfuOlIsvUq1TP3L6/xc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04590-PRO_0000038615	uniprotkb:Q13523	intact:EBI-863916	intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547	psi-mi:p04590-pro_0000038615(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)|uniprotkb:Pr55Gag(gene name synonym)	psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bennett et al. (2004)	pubmed:15452250	taxid:11720(hv2ro)|taxid:11720("Human immunodeficiency virus type 2 subtype A (isolate ROD) (HIV-2)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-780213	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-780156(chain-parent)	refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1	-	chain-seq-start:2|chain-seq-end:135|comment:It corresponds to fragment 1-135 of gag P04590|comment:P04590 -PRO_0000038615	-	comment:Although the presence matrix protein part of gag is sufficient to bind PRP4, the removal of both p2 and p6 impairs the binding.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/10	2014/10/16	rogid:8+UW0KQfgLWmvlnX8dAuLaiZIhw11720	rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606	intact-crc:83CDB5FED5794421|rigid:aWULrHKD0Q1rg4hamqspgJzTWkU	false	35s radiolabel:?-?	sufficient binding region:512-1007|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04590	uniprotkb:Q13523	intact:EBI-780156	intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547	psi-mi:gag_hv2ro(display_long)|uniprotkb:Pr55Gag(gene name synonym)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)	psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bennett et al. (2004)	pubmed:15452250	taxid:11720(hv2ro)|taxid:11720("Human immunodeficiency virus type 2 subtype A (isolate ROD) (HIV-2)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-780273	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4DGB|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|rcsb pdb:2WLV|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR036875|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)	refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1	-	-	-	comment:PRP4 binds specifically with HIV-2 gag but but not with HIV-1 gag.|comment:Although the fragments 1-687 and 512-1007 of PRP4 both bind gag, the fragment 512-687 does not seem to bind.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/10	2014/10/16	rogid:6l9T24/AOWtOk6d9Whne4zAef4g11720	rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606	intact-crc:C8744DB04FB9CB4A|rigid:5H85cYY2PaFCxrFuMQEr4NdrmUg	false	35s radiolabel:?-?	sufficient binding region:512-1007|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04590	uniprotkb:Q13523	intact:EBI-780156	intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547	psi-mi:gag_hv2ro(display_long)|uniprotkb:Pr55Gag(gene name synonym)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)	psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bennett et al. (2004)	pubmed:15452250	taxid:11720(hv2ro)|taxid:11720("Human immunodeficiency virus type 2 subtype A (isolate ROD) (HIV-2)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-780286	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4DGB|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|rcsb pdb:2WLV|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR036875|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)	refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1	-	-	-	comment:Although the fragments 1-687 and 512-1007 of PRP4 both bind gag, the fragment 512-687 does not seem to bind.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/10	2014/10/16	rogid:6l9T24/AOWtOk6d9Whne4zAef4g11720	rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606	intact-crc:3F635733608D2CE4|rigid:5H85cYY2PaFCxrFuMQEr4NdrmUg	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?|sufficient binding region:1-687	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04590	uniprotkb:Q13523	intact:EBI-780156	intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547	psi-mi:gag_hv2ro(display_long)|uniprotkb:Pr55Gag(gene name synonym)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)	psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bennett et al. (2004)	pubmed:15452250	taxid:11720(hv2ro)|taxid:11720("Human immunodeficiency virus type 2 subtype A (isolate ROD) (HIV-2)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-780242	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4DGB|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|rcsb pdb:2WLV|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR036875|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)	refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1	-	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/10	2014/10/16	rogid:6l9T24/AOWtOk6d9Whne4zAef4g11720	rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606	intact-crc:AACB3F6895C584FC|rigid:5H85cYY2PaFCxrFuMQEr4NdrmUg	false	35s radiolabel:?-?	sufficient binding region:1-1007|v5 tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P05894	uniprotkb:Q13523	intact:EBI-780408	intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547	psi-mi:gag_sivm1(display_long)|uniprotkb:Pr55Gag(gene name synonym)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)	psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Bennett et al. (2004)	pubmed:15452250	taxid:11733(sivm1)|taxid:11733("Simian immunodeficiency virus (isolate Mm142-83) (SIV-mac)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-780312	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR036875|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)	refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1	-	-	-	comment:Unlike HIV-2 gag and SIVmac gag, HTLV-1 gag does not impairs PRP4 kinase activity.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/10	2014/10/16	rogid:A0kVbfiVdREN5fOTpoVzCENK4JE11733	rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606	intact-crc:6034A6E3B5524E2E|rigid:kd4d1soeGgHSZzrYV1h+4Zolz0A	false	maltose binding protein tag:?-?	v5 tag:c-c|sufficient binding region:1-1007|his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P05894	uniprotkb:Q86U06	intact:EBI-780408	intact:EBI-780319|uniprotkb:Q8ND16|uniprotkb:Q8TB88|uniprotkb:Q8WY40|uniprotkb:Q9BUJ1|uniprotkb:Q9NVV7|uniprotkb:D3DS32|ensembl:ENSP00000352956	psi-mi:gag_sivm1(display_long)|uniprotkb:Pr55Gag(gene name synonym)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)	psi-mi:rbm23_human(display_long)|uniprotkb:RNA-binding motif protein 23(gene name synonym)|uniprotkb:RNA-binding region-containing protein 4(gene name synonym)|uniprotkb:Splicing factor SF2(gene name synonym)|uniprotkb:RBM23(gene name)|psi-mi:RBM23(display_short)|uniprotkb:RNPC4(gene name synonym)|uniprotkb:PP239(orf name)|uniprotkb:CAPER beta(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Bennett et al. (2004)	pubmed:15452250	taxid:11733(sivm1)|taxid:11733("Simian immunodeficiency virus (isolate Mm142-83) (SIV-mac)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-780312	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR036875|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)	refseq:NP_001070819.1|refseq:NP_001070820.1|refseq:NP_060577.3|refseq:NP_001294973.1|refseq:XP_016876896.1|refseq:XP_016876902.1|ensembl:ENSG00000100461(gene)|ensembl:ENST00000359890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q86U06|rcsb pdb:2CQ4|rcsb pdb:2DNZ	-	-	-	comment:Unlike HIV-2 gag and SIVmac gag, HTLV-1 gag does not impairs PRP4 kinase activity.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/10	2014/10/16	rogid:A0kVbfiVdREN5fOTpoVzCENK4JE11733	rogid:+u0lm/as9TcTOHwwPa2ON0HIiW49606	intact-crc:6034A6E3B5524E2E|rigid:kd4d1soeGgHSZzrYV1h+4Zolz0A	false	maltose binding protein tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04590	uniprotkb:Q13523	intact:EBI-780156	intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547	psi-mi:gag_hv2ro(display_long)|uniprotkb:Pr55Gag(gene name synonym)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)	psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Bennett et al. (2004)	pubmed:15452250	taxid:11720(hv2ro)|taxid:11720("Human immunodeficiency virus type 2 subtype A (isolate ROD) (HIV-2)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-852249	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4DGB|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|rcsb pdb:2WLV|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR036875|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)	refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1	-	-	-	comment:Unlike HIV-2 gag and SIVmac gag, HTLV-1 gag does not impairs PRP4 kinase activity.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/10	2014/10/16	rogid:6l9T24/AOWtOk6d9Whne4zAef4g11720	rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606	intact-crc:F2E3DEADB5F596EF|rigid:0XsJyuULh9onSWe0ppBl9cqpAx8	false	maltose binding protein tag:?-?	v5 tag:c-c|sufficient binding region:1-1007|his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04590	uniprotkb:Q86U06	intact:EBI-780156	intact:EBI-780319|uniprotkb:Q8ND16|uniprotkb:Q8TB88|uniprotkb:Q8WY40|uniprotkb:Q9BUJ1|uniprotkb:Q9NVV7|uniprotkb:D3DS32|ensembl:ENSP00000352956	psi-mi:gag_hv2ro(display_long)|uniprotkb:Pr55Gag(gene name synonym)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)	psi-mi:rbm23_human(display_long)|uniprotkb:RNA-binding motif protein 23(gene name synonym)|uniprotkb:RNA-binding region-containing protein 4(gene name synonym)|uniprotkb:Splicing factor SF2(gene name synonym)|uniprotkb:RBM23(gene name)|psi-mi:RBM23(display_short)|uniprotkb:RNPC4(gene name synonym)|uniprotkb:PP239(orf name)|uniprotkb:CAPER beta(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Bennett et al. (2004)	pubmed:15452250	taxid:11720(hv2ro)|taxid:11720("Human immunodeficiency virus type 2 subtype A (isolate ROD) (HIV-2)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-852249	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4DGB|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|rcsb pdb:2WLV|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR036875|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)	refseq:NP_001070819.1|refseq:NP_001070820.1|refseq:NP_060577.3|refseq:NP_001294973.1|refseq:XP_016876896.1|refseq:XP_016876902.1|ensembl:ENSG00000100461(gene)|ensembl:ENST00000359890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q86U06|rcsb pdb:2CQ4|rcsb pdb:2DNZ	-	-	-	comment:Unlike HIV-2 gag and SIVmac gag, HTLV-1 gag does not impairs PRP4 kinase activity.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/10	2014/10/16	rogid:6l9T24/AOWtOk6d9Whne4zAef4g11720	rogid:+u0lm/as9TcTOHwwPa2ON0HIiW49606	intact-crc:F2E3DEADB5F596EF|rigid:0XsJyuULh9onSWe0ppBl9cqpAx8	false	maltose binding protein tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13523	uniprotkb:P04590	intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547	intact:EBI-780156	psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym)	psi-mi:gag_hv2ro(display_long)|uniprotkb:Pr55Gag(gene name synonym)|uniprotkb:gag(gene name)|psi-mi:gag(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bennett et al. (2004)	pubmed:15452250	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:11720(hv2ro)|taxid:11720("Human immunodeficiency virus type 2 subtype A (isolate ROD) (HIV-2)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-780427	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1	rcsb pdb:4DGB|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR001878(Zinc finger, CCHC-type)|rcsb pdb:2WLV|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR036875|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)	-	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/01/10	2014/10/16	rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606	rogid:6l9T24/AOWtOk6d9Whne4zAef4g11720	intact-crc:4DBAE21C49806226|rigid:5H85cYY2PaFCxrFuMQEr4NdrmUg	false	ha tag:n-n|sufficient binding region:1-1007	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)