#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P07897 uniprotkb:Q05546 intact:EBI-1039762 intact:EBI-1039732 psi-mi:pgca_rat(display_long)|uniprotkb:Acan(gene name)|psi-mi:Acan(display_short)|uniprotkb:Agc(gene name synonym)|uniprotkb:Agc1(gene name synonym)|uniprotkb:Cartilage-specific proteoglycan core protein(gene name synonym) psi-mi:tenr_rat(display_long)|uniprotkb:Tnr(gene name)|psi-mi:Tnr(display_short)|uniprotkb:Restrictin(gene name synonym)|uniprotkb:Janusin(gene name synonym)|uniprotkb:Neural recognition molecule J1-160/180(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Lundell et al. (2004) pubmed:15296743 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1039787|rcsb pdb:1TDQ - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:68358|refseq:NP_071526.1|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR016187(C-type lectin fold)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR000538(Link)|interpro:IPR000436(Sushi/SCR/CCP)|mint:P07897|go:"GO:0001501"(skeletal system development)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0002063"(chondrocyte development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009749"(response to glucose)|go:"GO:0010447"(response to acidic pH)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0021510"(spinal cord development)|go:"GO:0030166"(proteoglycan biosynthetic process)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072534"(perineuronal net)|go:"GO:0098966"(perisynaptic extracellular matrix)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|rcsb pdb:1TDQ|reactome:R-RNO-1474228|reactome:R-RNO-2022854|reactome:R-RNO-2022857|reactome:R-RNO-3000178|go:"GO:0010259"(multicellular organism aging)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR033987|interpro:IPR035976|interpro:IPR036179 rgd:3886|refseq:NP_037177.1|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033079|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|mint:Q05546|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0045121"(membrane raft)|go:"GO:0048692"(negative regulation of axon extension involved in regeneration)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072534"(perineuronal net)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098966"(perisynaptic extracellular matrix)|go:"GO:0098978"(glutamatergic synapse)|rcsb pdb:1TDQ|reactome:R-RNO-3000178|interpro:IPR000742(EGF-like, type 3)|interpro:IPR036056|interpro:IPR036116|interpro:IPR041161 - - - assembly:dimeric, multimeric|3d-r-factors:working 79.100%, free 76.600%|3d-resolution:2.6A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:p2ezYwvORuZanug55ifaXR11p/s10116 rogid:Z810KbeOItf8zwgtic+nWX8azEM10116 intact-crc:B59BC56BA007E3B5|rigid:D6uLK9Q2OSpwVcivJ05K8CgFbD0 false sufficient binding region:1909-2037 sufficient binding region:502-771 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)