#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q63279 uniprotkb:P11530 intact:EBI-876985|ensembl:ENSRNOP00000019133|uniprotkb:A0JN08|uniprotkb:Q5M7V2|uniprotkb:Q6S6J4|uniprotkb:Q9Z253 intact:EBI-706166|ensembl:ENSRNOP00000029969|uniprotkb:F1M705 psi-mi:k1c19_rat(display_long)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Type I keratin Ka19(gene name synonym)|uniprotkb:Krt19(gene name)|psi-mi:Krt19(display_short)|uniprotkb:Ka19(gene name synonym)|uniprotkb:Krt1-19(gene name synonym) psi-mi:dmd_rat(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ursitti et al. (2004) pubmed:15247274 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-876995 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000014233(gene)|ensembl:ENSRNOT00000019133(transcript)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-RNO-6805567|reactome:R-RNO-6809371|rgd:619936|refseq:NP_955792.1 ensembl:ENSRNOG00000046366(gene)|ensembl:ENSRNOT00000035692(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|rgd:2507|refseq:XP_017457399.1|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014904"(myotube cell development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030154"(cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|reactome:R-RNO-390522 - - - comment:"The anti-dystrophin mAb was able to coimmunoprecipitate dystrophin (dmd) and krt19." taxid:1016(rat-skeletal_muscle)|taxid:1016(rat skeletal muscle) - 2006/03/07 2016/01/15 rogid:hJDHR+BA9IJwiim4mzAtK4gghNk10116 rogid:+tB82I1CIAu/nuaXmqNoSWqLp0o10116 intact-crc:3BE71928512B5BA8|rigid:iN5iEEQEzC7U4nrCHszVvzu3iMg false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P11530 uniprotkb:Q63279 intact:EBI-706166|ensembl:ENSRNOP00000029969|uniprotkb:F1M705 intact:EBI-876985|ensembl:ENSRNOP00000019133|uniprotkb:A0JN08|uniprotkb:Q5M7V2|uniprotkb:Q6S6J4|uniprotkb:Q9Z253 psi-mi:dmd_rat(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short) psi-mi:k1c19_rat(display_long)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Type I keratin Ka19(gene name synonym)|uniprotkb:Krt19(gene name)|psi-mi:Krt19(display_short)|uniprotkb:Ka19(gene name synonym)|uniprotkb:Krt1-19(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ursitti et al. (2004) pubmed:15247274 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-877009 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000046366(gene)|ensembl:ENSRNOT00000035692(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|rgd:2507|refseq:XP_017457399.1|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014904"(myotube cell development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030154"(cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|reactome:R-RNO-390522 ensembl:ENSRNOG00000014233(gene)|ensembl:ENSRNOT00000019133(transcript)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-RNO-6805567|reactome:R-RNO-6809371|rgd:619936|refseq:NP_955792.1 - - - comment:"The anti-krt19 mAb was able to coimmunoprecipitate dystrophin (dmd) and krt19." taxid:1016(rat-skeletal_muscle)|taxid:1016(rat skeletal muscle) - 2006/03/07 2016/01/15 rogid:+tB82I1CIAu/nuaXmqNoSWqLp0o10116 rogid:hJDHR+BA9IJwiim4mzAtK4gghNk10116 intact-crc:A62A467818DEDDDC|rigid:iN5iEEQEzC7U4nrCHszVvzu3iMg false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P11530 uniprotkb:Q63279 intact:EBI-706166|ensembl:ENSRNOP00000029969|uniprotkb:F1M705 intact:EBI-876985|ensembl:ENSRNOP00000019133|uniprotkb:A0JN08|uniprotkb:Q5M7V2|uniprotkb:Q6S6J4|uniprotkb:Q9Z253 psi-mi:dmd_rat(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short) psi-mi:k1c19_rat(display_long)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Type I keratin Ka19(gene name synonym)|uniprotkb:Krt19(gene name)|psi-mi:Krt19(display_short)|uniprotkb:Ka19(gene name synonym)|uniprotkb:Krt1-19(gene name synonym) psi-mi:"MI:0399"(two hybrid fragment pooling approach) Ursitti et al. (2004) pubmed:15247274 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-877030 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000046366(gene)|ensembl:ENSRNOT00000035692(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|rgd:2507|refseq:XP_017457399.1|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014904"(myotube cell development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030154"(cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|reactome:R-RNO-390522 ensembl:ENSRNOG00000014233(gene)|ensembl:ENSRNOT00000019133(transcript)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-RNO-6805567|reactome:R-RNO-6809371|rgd:619936|refseq:NP_955792.1 - - - comment:Transfection of COS-7 cells with krt19, krt8 and dys-ABD showed that the actin-binding domain of dystrophin associates preferentially with the network of filaments formed in the cytoplasm by the krt8 and krt19 cytokeratins. taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2006/03/07 2016/01/15 rogid:+tB82I1CIAu/nuaXmqNoSWqLp0o10116 rogid:hJDHR+BA9IJwiim4mzAtK4gghNk10116 intact-crc:2526FFDF5A93C361|rigid:Nvn/Wq+S8KXVIBE9vjJsmt/xT3o false binding-associated region:?-?|green fluorescent protein tag:n-n - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P11530 uniprotkb:Q10758 intact:EBI-706166|ensembl:ENSRNOP00000029969|uniprotkb:F1M705 intact:EBI-877046|ensembl:ENSRNOP00000029068|uniprotkb:Q5WPB3 psi-mi:dmd_rat(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short) psi-mi:k2c8_rat(display_long)|uniprotkb:Keratin-8(gene name synonym)|uniprotkb:Cytokeratin-8(gene name synonym)|uniprotkb:Cytokeratin endo A(gene name synonym)|uniprotkb:Krt8(gene name)|psi-mi:Krt8(display_short)|uniprotkb:Krt2-8(gene name synonym)|uniprotkb:Type-II keratin Kb8(gene name synonym) psi-mi:"MI:0399"(two hybrid fragment pooling approach) Ursitti et al. (2004) pubmed:15247274 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-877030 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000046366(gene)|ensembl:ENSRNOT00000035692(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|rgd:2507|refseq:XP_017457399.1|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014904"(myotube cell development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030154"(cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|reactome:R-RNO-390522 ensembl:ENSRNOG00000009779(gene)|ensembl:ENSRNOT00000038480(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045095"(keratin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0051707"(response to other organism)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0071944"(cell periphery)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:Q10758|reactome:R-RNO-6805567|reactome:R-RNO-6809371|rgd:2984|refseq:NP_955402.1 - - - comment:Transfection of COS-7 cells with krt19, krt8 and dys-ABD showed that the actin-binding domain of dystrophin associates preferentially with the network of filaments formed in the cytoplasm by the krt8 and krt19 cytokeratins. taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2006/03/07 2016/01/15 rogid:+tB82I1CIAu/nuaXmqNoSWqLp0o10116 rogid:ATpfAaPsbtrq1tTuSE8L8COOLBw10116 intact-crc:2526FFDF5A93C361|rigid:Nvn/Wq+S8KXVIBE9vjJsmt/xT3o false binding-associated region:?-?|green fluorescent protein tag:n-n myc tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)