#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9H8S9	uniprotkb:Q15208	intact:EBI-748229|uniprotkb:Q53S34|uniprotkb:Q9H3T5|uniprotkb:Q9HAI0|uniprotkb:Q9NVE2|ensembl:ENSP00000379364	intact:EBI-458376|ensembl:ENSP00000229812|uniprotkb:Q503A1	psi-mi:mob1a_human(display_long)|uniprotkb:MOB1A(gene name)|psi-mi:MOB1A(display_short)|uniprotkb:C2orf6(gene name synonym)|uniprotkb:MOB4B(gene name synonym)|uniprotkb:MOBK1B(gene name synonym)|uniprotkb:MOBKL1B(gene name synonym)|uniprotkb:Mob1 alpha(gene name synonym)|uniprotkb:Mob1 homolog 1B(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 1B(gene name synonym)	psi-mi:stk38_human(display_long)|uniprotkb:NDR1(gene name synonym)|uniprotkb:STK38(gene name)|psi-mi:STK38(display_short)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bichsel et al. (2004)	imex:IM-14532|pubmed:15197186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-991340|imex:IM-14532-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304039.1|refseq:NP_001304040.1|refseq:NP_001304041.1|refseq:NP_060691.2|ensembl:ENSG00000114978(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0035329"(hippo signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9H8S9|rcsb pdb:1PI1|rcsb pdb:4J1V|rcsb pdb:4JIZ|rcsb pdb:5BRK|rcsb pdb:5BRM|rcsb pdb:5TWF|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:5XQZ|rcsb pdb:6MCP|rcsb pdb:6MCQ|reactome:R-HSA-2028269|ensembl:ENST00000396049(transcript)|dip:DIP-36594N	ensembl:ENSG00000112079(gene)|ensembl:ENST00000229812(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q15208|rcsb pdb:1PSB|rcsb pdb:6BXI|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:NP_009202.1|refseq:XP_006715051.1|refseq:XP_006715052.1|refseq:NP_001292031.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:2A, 2C and 4|comment:"Interaction was increased in OA (okadaic acid) treated cells."|comment:"Cos1 cells have been transfected with MOBk1B and STK38 and have been treated with OA (okadaic acid) prior to lysis. Alternatively, Cos1 cells have been transfected separately, treated with OA prior to lysis and lysates have neen combined. Interaction heas been observed independent of OA-treatment of STK38/NDR1-transfected cells."|comment:Kinase-dead STK38 mutant lys118ala showed interaction in OA-treated cells.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/08/18	2014/10/16	rogid:Gup4pRYJH3cfC6+XkgI27yiF7g89606	rogid:YHzdDrPEH6YdhOXtcnLWArqftck9606	intact-crc:5C8822A6D624D47F|rigid:LRZYhT2RePHk89WXN3qUWdurM4s	false	myc tag:?-?	ha tag:?-?|mutation disrupting interaction:41-41|mutation disrupting interaction:31-31|mutation disrupting interaction:74-74|mutation disrupting interaction:78-78|mutation decreasing interaction:24-24|mutation decreasing interaction:44-44|mutation decreasing interaction:79-79	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H8S9	uniprotkb:Q15208	intact:EBI-748229|uniprotkb:Q53S34|uniprotkb:Q9H3T5|uniprotkb:Q9HAI0|uniprotkb:Q9NVE2|ensembl:ENSP00000379364	intact:EBI-458376|ensembl:ENSP00000229812|uniprotkb:Q503A1	psi-mi:mob1a_human(display_long)|uniprotkb:MOB1A(gene name)|psi-mi:MOB1A(display_short)|uniprotkb:C2orf6(gene name synonym)|uniprotkb:MOB4B(gene name synonym)|uniprotkb:MOBK1B(gene name synonym)|uniprotkb:MOBKL1B(gene name synonym)|uniprotkb:Mob1 alpha(gene name synonym)|uniprotkb:Mob1 homolog 1B(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 1B(gene name synonym)	psi-mi:stk38_human(display_long)|uniprotkb:NDR1(gene name synonym)|uniprotkb:STK38(gene name)|psi-mi:STK38(display_short)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bichsel et al. (2004)	imex:IM-14532|pubmed:15197186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-991394|imex:IM-14532-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304039.1|refseq:NP_001304040.1|refseq:NP_001304041.1|refseq:NP_060691.2|ensembl:ENSG00000114978(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0035329"(hippo signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9H8S9|rcsb pdb:1PI1|rcsb pdb:4J1V|rcsb pdb:4JIZ|rcsb pdb:5BRK|rcsb pdb:5BRM|rcsb pdb:5TWF|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:5XQZ|rcsb pdb:6MCP|rcsb pdb:6MCQ|reactome:R-HSA-2028269|ensembl:ENST00000396049(transcript)|dip:DIP-36594N	ensembl:ENSG00000112079(gene)|ensembl:ENST00000229812(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q15208|rcsb pdb:1PSB|rcsb pdb:6BXI|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:NP_009202.1|refseq:XP_006715051.1|refseq:XP_006715052.1|refseq:NP_001292031.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:2B|comment:"Interaction was increased in OA (okadaic acid) treated cells."|comment:"Cos1 cells have been transfected with MOBk1B and STK38 and have been treates with OA (okadaic acid) prior to lysis."|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/08/18	2014/10/16	rogid:Gup4pRYJH3cfC6+XkgI27yiF7g89606	rogid:YHzdDrPEH6YdhOXtcnLWArqftck9606	intact-crc:C03A8711AD2A4102|rigid:LRZYhT2RePHk89WXN3qUWdurM4s	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y2H1	-	intact:EBI-991501|uniprotkb:Q8TBX7|uniprotkb:A8K4U0|uniprotkb:B4E3J8|ensembl:ENSP00000373684	-	psi-mi:st38l_human(display_long)|uniprotkb:NDR2 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 2(gene name synonym)|uniprotkb:STK38L(gene name)|psi-mi:STK38L(display_short)|uniprotkb:KIAA0965(gene name synonym)|uniprotkb:NDR2(gene name synonym)	-	psi-mi:"MI:0424"(protein kinase assay)	Bichsel et al. (2004)	imex:IM-14532|pubmed:15197186	taxid:9606(human)|taxid:9606(Homo sapiens)	-	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-991608|imex:IM-14532-1	-	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0326"(protein)	-	refseq:XP_006719121.1|ensembl:ENSG00000211455(gene)|ensembl:ENST00000389032(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003779"(actin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051128"(regulation of cellular component organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q9Y2H1|rcsb pdb:5XQZ|refseq:NP_055815.1|refseq:XP_011518915.1|refseq:XP_016874525.1	-	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	resulting-ptm:Autophosphorylation of STK38L at sites Thr-75 and Ser-282.|stimulant:"Autophosphorylation was stimulated by presence of MOBK1B (UniProt Ac: Q9H8S9)"|figure legend:1B|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/18	2014/10/16	rogid:lKXWdkeLMD/YCxa1oQz9k0aoW3I9606	-	intact-crc:CA079B01D857D384	false	tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	-
uniprotkb:Q9Y2H1	uniprotkb:Q9H8S9	intact:EBI-991501|uniprotkb:Q8TBX7|uniprotkb:A8K4U0|uniprotkb:B4E3J8|ensembl:ENSP00000373684	intact:EBI-748229|uniprotkb:Q53S34|uniprotkb:Q9H3T5|uniprotkb:Q9HAI0|uniprotkb:Q9NVE2|ensembl:ENSP00000379364	psi-mi:st38l_human(display_long)|uniprotkb:NDR2 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 2(gene name synonym)|uniprotkb:STK38L(gene name)|psi-mi:STK38L(display_short)|uniprotkb:KIAA0965(gene name synonym)|uniprotkb:NDR2(gene name synonym)	psi-mi:mob1a_human(display_long)|uniprotkb:MOB1A(gene name)|psi-mi:MOB1A(display_short)|uniprotkb:C2orf6(gene name synonym)|uniprotkb:MOB4B(gene name synonym)|uniprotkb:MOBK1B(gene name synonym)|uniprotkb:MOBKL1B(gene name synonym)|uniprotkb:Mob1 alpha(gene name synonym)|uniprotkb:Mob1 homolog 1B(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bichsel et al. (2004)	imex:IM-14532|pubmed:15197186	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-991487|imex:IM-14532-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006719121.1|ensembl:ENSG00000211455(gene)|ensembl:ENST00000389032(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003779"(actin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051128"(regulation of cellular component organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q9Y2H1|rcsb pdb:5XQZ|refseq:NP_055815.1|refseq:XP_011518915.1|refseq:XP_016874525.1	refseq:NP_001304039.1|refseq:NP_001304040.1|refseq:NP_001304041.1|refseq:NP_060691.2|ensembl:ENSG00000114978(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0035329"(hippo signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9H8S9|rcsb pdb:1PI1|rcsb pdb:4J1V|rcsb pdb:4JIZ|rcsb pdb:5BRK|rcsb pdb:5BRM|rcsb pdb:5TWF|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:5XQZ|rcsb pdb:6MCP|rcsb pdb:6MCQ|reactome:R-HSA-2028269|ensembl:ENST00000396049(transcript)|dip:DIP-36594N	psi-mi:"MI:0469"(intact)	-	-	figure legend:5B|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/18	2014/10/16	rogid:lKXWdkeLMD/YCxa1oQz9k0aoW3I9606	rogid:Gup4pRYJH3cfC6+XkgI27yiF7g89606	intact-crc:71C2E85B281421AB|rigid:A9Bxh7gjlHDhNj+iJfoY+iO+ofU	false	mutation disrupting interaction:32-32|tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)