#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P34208	uniprotkb:P06652	intact:EBI-768535|ensemblfungi:"SPCC1259.13.1:pep"	intact:EBI-1153367|ensemblfungi:"SPAC24H6.05.1:pep"	psi-mi:chk1_schpo(display_long)|uniprotkb:Checkpoint kinase 1(gene name synonym)|uniprotkb:chk1(gene name)|psi-mi:chk1(display_short)|uniprotkb:rad27(gene name synonym)|uniprotkb:SPCC1259.13(orf name)	psi-mi:mpip_schpo(display_long)|uniprotkb:cdc25(gene name)|psi-mi:cdc25(display_short)|uniprotkb:SPAC24H6.05(orf name)|uniprotkb:Mitosis initiation protein(gene name synonym)|uniprotkb:P80(gene name synonym)	psi-mi:"MI:0423"(in-gel kinase assay)	Mochida et al. (2004)	pubmed:14739927	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153356	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_588070.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR034670|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990260"(negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling)|ensemblfungi:SPCC1259.13(gene)|ensemblfungi:SPCC1259.13.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0051598"(meiotic recombination checkpoint signaling)	interpro:IPR036873|refseq:NP_592947.1|interpro:IPR000751(M-phase inducer phosphatase)|interpro:IPR001763(Rhodanese-like)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051728"(cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0072435"(response to mitotic G2 DNA damage checkpoint signaling)|go:"GO:0110032"(positive regulation of G2/MI transition of meiotic cell cycle)|ensemblfungi:SPAC24H6.05.1(transcript)|ensemblfungi:SPAC24H6.05(gene)|reactome:R-SPO-156711|reactome:R-SPO-176187|reactome:R-SPO-5625740|reactome:R-SPO-69273|reactome:R-SPO-69601|reactome:R-SPO-75035|reactome:R-SPO-5689880|reactome:R-SPO-69656|reactome:R-SPO-6804115|reactome:R-SPO-69202	-	-	-	figure legend:Fig. 1A, 1B, 1C|comment:This interaction is stimulated by UV irradiation or loss of function mutations in swi7, cdc6 or cdc20.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/02	2014/10/16	rogid:HaZot8UynlmYYTouVp5t07GSW9w284812	rogid:JA2sUvwAEOi7Mgc7yCosqNw2tbs284812	intact-crc:6C7A5FF43BE7CACC|rigid:5/BrV9s1kFzF7jXbvHFFCqEZtvM	false	ha tag:c-c|mutation disrupting interaction:155-155	sufficient binding region:60-160|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P34208	uniprotkb:P87074	intact:EBI-768535|ensemblfungi:"SPCC1259.13.1:pep"	intact:EBI-768448|uniprotkb:Q09754|ensemblfungi:"SPBC342.05.1:pep"	psi-mi:chk1_schpo(display_long)|uniprotkb:Checkpoint kinase 1(gene name synonym)|uniprotkb:chk1(gene name)|psi-mi:chk1(display_short)|uniprotkb:rad27(gene name synonym)|uniprotkb:SPCC1259.13(orf name)	psi-mi:rhp9_schpo(display_long)|uniprotkb:crb2(gene name)|psi-mi:crb2(display_short)|uniprotkb:Checkpoint mediator protein crb2(gene name synonym)|uniprotkb:Cut5-repeat binding protein 2(gene name synonym)|uniprotkb:RAD9 protein homolog(gene name synonym)|uniprotkb:rhp9(gene name synonym)|uniprotkb:SPBC342.05(orf name)	psi-mi:"MI:0423"(in-gel kinase assay)	Mochida et al. (2004)	pubmed:14739927	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153356	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_588070.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR034670|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990260"(negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling)|ensemblfungi:SPCC1259.13(gene)|ensemblfungi:SPCC1259.13.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0051598"(meiotic recombination checkpoint signaling)	rcsb pdb:4BU0|rcsb pdb:4BU1|refseq:NP_596748.1|interpro:IPR001357(BRCT)|rcsb pdb:2FHD|rcsb pdb:2VXB|rcsb pdb:2VXC|interpro:IPR036420|interpro:IPR041297|reactome:R-SPO-3232118|ensemblfungi:SPBC342.05(gene)|ensemblfungi:SPBC342.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140463"(chromatin-protein adaptor)	-	-	-	figure legend:Fig. 1A, 1B, 1C|comment:This interaction is stimulated by UV irradiation or loss of function mutations in swi7, cdc6 or cdc20.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/02	2014/10/16	rogid:HaZot8UynlmYYTouVp5t07GSW9w284812	rogid:oHsEyMA31ahL6m7wLIQUp6TLagk284812	intact-crc:6C7A5FF43BE7CACC|rigid:5/BrV9s1kFzF7jXbvHFFCqEZtvM	false	ha tag:c-c|mutation disrupting interaction:155-155	necessary binding region:547-778	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13541	uniprotkb:Q02099	intact:EBI-74090|uniprotkb:B2R502|uniprotkb:Q6IBN3|uniprotkb:D3DSW8|ensembl:ENSP00000340691	intact:EBI-768555|uniprotkb:Q92391|uniprotkb:Q9UUM1|ensemblfungi:"SPBC216.05.1:pep"	psi-mi:4ebp1_human(display_long)|uniprotkb:Phosphorylated heat- and acid-stable protein regulated by insulin 1(gene name synonym)|uniprotkb:EIF4EBP1(gene name)|psi-mi:EIF4EBP1(display_short)	psi-mi:rad3_schpo(display_long)|uniprotkb:DNA repair protein rad3(gene name synonym)|uniprotkb:rad3(gene name)|psi-mi:rad3(display_short)|uniprotkb:SPBC216.05(orf name)	psi-mi:"MI:0423"(in-gel kinase assay)	Mochida et al. (2004)	pubmed:14739927	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153508	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004086.1|ensembl:ENSP00000340691|ensembl:ENSG00000187840(gene)|ensembl:ENST00000338825(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-30944N|go:"GO:0005829"(cytosol)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0030324"(lung development)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045471"(response to ethanol)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|interpro:IPR037582|mint:Q13541|rcsb pdb:1EJ4|rcsb pdb:1EJH|rcsb pdb:1WKW|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:2V8W|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:3HXG|rcsb pdb:3HXI|rcsb pdb:3M93|rcsb pdb:3M94|rcsb pdb:3U7X|rcsb pdb:4UED|rcsb pdb:5BXV|rcsb pdb:5EKV|rcsb pdb:5NVN|rcsb pdb:5WBJ|rcsb pdb:6BCU|rcsb pdb:6BCX|reactome:R-HSA-166208|reactome:R-HSA-72662	refseq:NP_595357.1|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR018936|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR014009(PIK-related kinase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012993(UME)|interpro:IPR036940|ensemblfungi:SPBC216.05(gene)|ensemblfungi:SPBC216.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0033315"(meiotic G2/MI DNA replication checkpoint signaling)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070310"(ATR-ATRIP complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072371"("histone kinase activity (H2A-S121 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1904514"(positive regulation of initiation of premeiotic DNA replication)	-	-	-	figure legend:Fig. 6	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/02	2014/10/16	rogid:abkjWitYZ9erPSlC88IWI2FtKto9606	rogid:6qu9ae5L6QdgpHZvEfWksxbBvpo284812	intact-crc:45D09EA041E6E3B6|rigid:eX3uWF/VnjjLLhzxKLp+0Nx/+e0	false	-	glutathione s tranferase tag:n-n|mutation disrupting interaction:2249-2249	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13541	uniprotkb:P87074	intact:EBI-74090|uniprotkb:B2R502|uniprotkb:Q6IBN3|uniprotkb:D3DSW8|ensembl:ENSP00000340691	intact:EBI-768448|uniprotkb:Q09754|ensemblfungi:"SPBC342.05.1:pep"	psi-mi:4ebp1_human(display_long)|uniprotkb:Phosphorylated heat- and acid-stable protein regulated by insulin 1(gene name synonym)|uniprotkb:EIF4EBP1(gene name)|psi-mi:EIF4EBP1(display_short)	psi-mi:rhp9_schpo(display_long)|uniprotkb:crb2(gene name)|psi-mi:crb2(display_short)|uniprotkb:Checkpoint mediator protein crb2(gene name synonym)|uniprotkb:Cut5-repeat binding protein 2(gene name synonym)|uniprotkb:RAD9 protein homolog(gene name synonym)|uniprotkb:rhp9(gene name synonym)|uniprotkb:SPBC342.05(orf name)	psi-mi:"MI:0423"(in-gel kinase assay)	Mochida et al. (2004)	pubmed:14739927	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153508	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004086.1|ensembl:ENSP00000340691|ensembl:ENSG00000187840(gene)|ensembl:ENST00000338825(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-30944N|go:"GO:0005829"(cytosol)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0030324"(lung development)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045471"(response to ethanol)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|interpro:IPR037582|mint:Q13541|rcsb pdb:1EJ4|rcsb pdb:1EJH|rcsb pdb:1WKW|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:2V8W|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:3HXG|rcsb pdb:3HXI|rcsb pdb:3M93|rcsb pdb:3M94|rcsb pdb:3U7X|rcsb pdb:4UED|rcsb pdb:5BXV|rcsb pdb:5EKV|rcsb pdb:5NVN|rcsb pdb:5WBJ|rcsb pdb:6BCU|rcsb pdb:6BCX|reactome:R-HSA-166208|reactome:R-HSA-72662	rcsb pdb:4BU0|rcsb pdb:4BU1|refseq:NP_596748.1|interpro:IPR001357(BRCT)|rcsb pdb:2FHD|rcsb pdb:2VXB|rcsb pdb:2VXC|interpro:IPR036420|interpro:IPR041297|reactome:R-SPO-3232118|ensemblfungi:SPBC342.05(gene)|ensemblfungi:SPBC342.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140463"(chromatin-protein adaptor)	-	-	-	figure legend:Fig. 6	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/02	2014/10/16	rogid:abkjWitYZ9erPSlC88IWI2FtKto9606	rogid:oHsEyMA31ahL6m7wLIQUp6TLagk284812	intact-crc:45D09EA041E6E3B6|rigid:eX3uWF/VnjjLLhzxKLp+0Nx/+e0	false	-	sufficient binding region:535-778|mutation decreasing interaction:666-666	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P34208	uniprotkb:P34208	intact:EBI-768535|ensemblfungi:"SPCC1259.13.1:pep"	intact:EBI-768535|ensemblfungi:"SPCC1259.13.1:pep"	psi-mi:chk1_schpo(display_long)|uniprotkb:Checkpoint kinase 1(gene name synonym)|uniprotkb:chk1(gene name)|psi-mi:chk1(display_short)|uniprotkb:rad27(gene name synonym)|uniprotkb:SPCC1259.13(orf name)	psi-mi:chk1_schpo(display_long)|uniprotkb:Checkpoint kinase 1(gene name synonym)|uniprotkb:chk1(gene name)|psi-mi:chk1(display_short)|uniprotkb:rad27(gene name synonym)|uniprotkb:SPCC1259.13(orf name)	psi-mi:"MI:0423"(in-gel kinase assay)	Mochida et al. (2004)	pubmed:14739927	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153390	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_588070.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR034670|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990260"(negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling)|ensemblfungi:SPCC1259.13(gene)|ensemblfungi:SPCC1259.13.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0051598"(meiotic recombination checkpoint signaling)	refseq:NP_588070.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR034670|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990260"(negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling)|ensemblfungi:SPCC1259.13(gene)|ensemblfungi:SPCC1259.13.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0051598"(meiotic recombination checkpoint signaling)	-	-	-	figure legend:Fig. 1A, 1B, 1C|comment:This interaction is stimulated by UV irradiation or loss of function mutations in swi7, cdc6 or cdc20.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/02	2014/10/16	rogid:HaZot8UynlmYYTouVp5t07GSW9w284812	rogid:HaZot8UynlmYYTouVp5t07GSW9w284812	intact-crc:63C398AB5D028F3B|rigid:iQzYBRWf/mVTlct92Wg2vB7tt6g	false	mutation disrupting interaction:155-155|ha tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P34208	uniprotkb:P87074	intact:EBI-768535|ensemblfungi:"SPCC1259.13.1:pep"	intact:EBI-768448|uniprotkb:Q09754|ensemblfungi:"SPBC342.05.1:pep"	psi-mi:chk1_schpo(display_long)|uniprotkb:Checkpoint kinase 1(gene name synonym)|uniprotkb:chk1(gene name)|psi-mi:chk1(display_short)|uniprotkb:rad27(gene name synonym)|uniprotkb:SPCC1259.13(orf name)	psi-mi:rhp9_schpo(display_long)|uniprotkb:crb2(gene name)|psi-mi:crb2(display_short)|uniprotkb:Checkpoint mediator protein crb2(gene name synonym)|uniprotkb:Cut5-repeat binding protein 2(gene name synonym)|uniprotkb:RAD9 protein homolog(gene name synonym)|uniprotkb:rhp9(gene name synonym)|uniprotkb:SPBC342.05(orf name)	psi-mi:"MI:0423"(in-gel kinase assay)	Mochida et al. (2004)	pubmed:14739927	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153390	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_588070.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR034670|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990260"(negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling)|ensemblfungi:SPCC1259.13(gene)|ensemblfungi:SPCC1259.13.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0051598"(meiotic recombination checkpoint signaling)	rcsb pdb:4BU0|rcsb pdb:4BU1|refseq:NP_596748.1|interpro:IPR001357(BRCT)|rcsb pdb:2FHD|rcsb pdb:2VXB|rcsb pdb:2VXC|interpro:IPR036420|interpro:IPR041297|reactome:R-SPO-3232118|ensemblfungi:SPBC342.05(gene)|ensemblfungi:SPBC342.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140463"(chromatin-protein adaptor)	-	-	-	figure legend:Fig. 1A, 1B, 1C|comment:This interaction is stimulated by UV irradiation or loss of function mutations in swi7, cdc6 or cdc20.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/02	2014/10/16	rogid:HaZot8UynlmYYTouVp5t07GSW9w284812	rogid:oHsEyMA31ahL6m7wLIQUp6TLagk284812	intact-crc:63C398AB5D028F3B|rigid:iQzYBRWf/mVTlct92Wg2vB7tt6g	false	mutation disrupting interaction:155-155|ha tag:c-c	necessary binding region:547-778	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P87074	uniprotkb:Q02099	intact:EBI-768448|uniprotkb:Q09754|ensemblfungi:"SPBC342.05.1:pep"	intact:EBI-768555|uniprotkb:Q92391|uniprotkb:Q9UUM1|ensemblfungi:"SPBC216.05.1:pep"	psi-mi:rhp9_schpo(display_long)|uniprotkb:crb2(gene name)|psi-mi:crb2(display_short)|uniprotkb:Checkpoint mediator protein crb2(gene name synonym)|uniprotkb:Cut5-repeat binding protein 2(gene name synonym)|uniprotkb:RAD9 protein homolog(gene name synonym)|uniprotkb:rhp9(gene name synonym)|uniprotkb:SPBC342.05(orf name)	psi-mi:rad3_schpo(display_long)|uniprotkb:DNA repair protein rad3(gene name synonym)|uniprotkb:rad3(gene name)|psi-mi:rad3(display_short)|uniprotkb:SPBC216.05(orf name)	psi-mi:"MI:0096"(pull down)	Mochida et al. (2004)	pubmed:14739927	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153431	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4BU0|rcsb pdb:4BU1|refseq:NP_596748.1|interpro:IPR001357(BRCT)|rcsb pdb:2FHD|rcsb pdb:2VXB|rcsb pdb:2VXC|interpro:IPR036420|interpro:IPR041297|reactome:R-SPO-3232118|ensemblfungi:SPBC342.05(gene)|ensemblfungi:SPBC342.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140463"(chromatin-protein adaptor)	refseq:NP_595357.1|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR018936|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR014009(PIK-related kinase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012993(UME)|interpro:IPR036940|ensemblfungi:SPBC216.05(gene)|ensemblfungi:SPBC216.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0033315"(meiotic G2/MI DNA replication checkpoint signaling)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070310"(ATR-ATRIP complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072371"("histone kinase activity (H2A-S121 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1904514"(positive regulation of initiation of premeiotic DNA replication)	-	-	-	figure legend:Fig. 3A	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/11/02	2014/10/16	rogid:oHsEyMA31ahL6m7wLIQUp6TLagk284812	rogid:6qu9ae5L6QdgpHZvEfWksxbBvpo284812	intact-crc:A2CE047C0EAF3A43|rigid:d41kRt2bExVW86NLovYTSEOFpOk	false	-	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P87074	uniprotkb:Q02099	intact:EBI-768448|uniprotkb:Q09754|ensemblfungi:"SPBC342.05.1:pep"	intact:EBI-768555|uniprotkb:Q92391|uniprotkb:Q9UUM1|ensemblfungi:"SPBC216.05.1:pep"	psi-mi:rhp9_schpo(display_long)|uniprotkb:crb2(gene name)|psi-mi:crb2(display_short)|uniprotkb:Checkpoint mediator protein crb2(gene name synonym)|uniprotkb:Cut5-repeat binding protein 2(gene name synonym)|uniprotkb:RAD9 protein homolog(gene name synonym)|uniprotkb:rhp9(gene name synonym)|uniprotkb:SPBC342.05(orf name)	psi-mi:rad3_schpo(display_long)|uniprotkb:DNA repair protein rad3(gene name synonym)|uniprotkb:rad3(gene name)|psi-mi:rad3(display_short)|uniprotkb:SPBC216.05(orf name)	psi-mi:"MI:0096"(pull down)	Mochida et al. (2004)	pubmed:14739927	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153437	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4BU0|rcsb pdb:4BU1|refseq:NP_596748.1|interpro:IPR001357(BRCT)|rcsb pdb:2FHD|rcsb pdb:2VXB|rcsb pdb:2VXC|interpro:IPR036420|interpro:IPR041297|reactome:R-SPO-3232118|ensemblfungi:SPBC342.05(gene)|ensemblfungi:SPBC342.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140463"(chromatin-protein adaptor)	refseq:NP_595357.1|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR018936|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR014009(PIK-related kinase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012993(UME)|interpro:IPR036940|ensemblfungi:SPBC216.05(gene)|ensemblfungi:SPBC216.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0033315"(meiotic G2/MI DNA replication checkpoint signaling)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070310"(ATR-ATRIP complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072371"("histone kinase activity (H2A-S121 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1904514"(positive regulation of initiation of premeiotic DNA replication)	-	-	-	figure legend:Fig. 3B, 3C, 4A, 4B|comment:This interaction is transiently reduced following UV irradiation.	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/11/02	2014/10/16	rogid:oHsEyMA31ahL6m7wLIQUp6TLagk284812	rogid:6qu9ae5L6QdgpHZvEfWksxbBvpo284812	intact-crc:389E09A539088996|rigid:d41kRt2bExVW86NLovYTSEOFpOk	false	ha tag:n-n|sufficient binding region:535-778	glutathione s tranferase tag:n-n|sufficient binding region:1-439	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P34208	uniprotkb:Q02099	intact:EBI-768535|ensemblfungi:"SPCC1259.13.1:pep"	intact:EBI-768555|uniprotkb:Q92391|uniprotkb:Q9UUM1|ensemblfungi:"SPBC216.05.1:pep"	psi-mi:chk1_schpo(display_long)|uniprotkb:Checkpoint kinase 1(gene name synonym)|uniprotkb:chk1(gene name)|psi-mi:chk1(display_short)|uniprotkb:rad27(gene name synonym)|uniprotkb:SPCC1259.13(orf name)	psi-mi:rad3_schpo(display_long)|uniprotkb:DNA repair protein rad3(gene name synonym)|uniprotkb:rad3(gene name)|psi-mi:rad3(display_short)|uniprotkb:SPBC216.05(orf name)	psi-mi:"MI:0096"(pull down)	Mochida et al. (2004)	pubmed:14739927	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153455	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_588070.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR034670|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990260"(negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling)|ensemblfungi:SPCC1259.13(gene)|ensemblfungi:SPCC1259.13.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0051598"(meiotic recombination checkpoint signaling)	refseq:NP_595357.1|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR018936|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR014009(PIK-related kinase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012993(UME)|interpro:IPR036940|ensemblfungi:SPBC216.05(gene)|ensemblfungi:SPBC216.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0033315"(meiotic G2/MI DNA replication checkpoint signaling)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070310"(ATR-ATRIP complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072371"("histone kinase activity (H2A-S121 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1904514"(positive regulation of initiation of premeiotic DNA replication)	-	-	-	figure legend:Fig. 4C, 4D|comment:This interaction is transiently reduced following UV irradiation.	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/11/02	2014/10/16	rogid:HaZot8UynlmYYTouVp5t07GSW9w284812	rogid:6qu9ae5L6QdgpHZvEfWksxbBvpo284812	intact-crc:DFA680980A4FA4A4|rigid:dgprm0aF56MuCcRaHTl2PhwfdgY	false	ha tag:n-n	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P34208	uniprotkb:P87074	intact:EBI-768535|ensemblfungi:"SPCC1259.13.1:pep"	intact:EBI-768448|uniprotkb:Q09754|ensemblfungi:"SPBC342.05.1:pep"	psi-mi:chk1_schpo(display_long)|uniprotkb:Checkpoint kinase 1(gene name synonym)|uniprotkb:chk1(gene name)|psi-mi:chk1(display_short)|uniprotkb:rad27(gene name synonym)|uniprotkb:SPCC1259.13(orf name)	psi-mi:rhp9_schpo(display_long)|uniprotkb:crb2(gene name)|psi-mi:crb2(display_short)|uniprotkb:Checkpoint mediator protein crb2(gene name synonym)|uniprotkb:Cut5-repeat binding protein 2(gene name synonym)|uniprotkb:RAD9 protein homolog(gene name synonym)|uniprotkb:rhp9(gene name synonym)|uniprotkb:SPBC342.05(orf name)	psi-mi:"MI:0096"(pull down)	Mochida et al. (2004)	pubmed:14739927	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153484	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_588070.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR034670|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990260"(negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling)|ensemblfungi:SPCC1259.13(gene)|ensemblfungi:SPCC1259.13.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0051598"(meiotic recombination checkpoint signaling)	rcsb pdb:4BU0|rcsb pdb:4BU1|refseq:NP_596748.1|interpro:IPR001357(BRCT)|rcsb pdb:2FHD|rcsb pdb:2VXB|rcsb pdb:2VXC|interpro:IPR036420|interpro:IPR041297|reactome:R-SPO-3232118|ensemblfungi:SPBC342.05(gene)|ensemblfungi:SPBC342.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140463"(chromatin-protein adaptor)	-	-	-	figure legend:Fig. 5A, 5B, 5C|comment:This interaction is transiently enhanced following UV irradiation.	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/11/02	2014/10/16	rogid:HaZot8UynlmYYTouVp5t07GSW9w284812	rogid:oHsEyMA31ahL6m7wLIQUp6TLagk284812	intact-crc:01015C1F14151113|rigid:iQzYBRWf/mVTlct92Wg2vB7tt6g	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q02099	uniprotkb:P87074	intact:EBI-768555|uniprotkb:Q92391|uniprotkb:Q9UUM1|ensemblfungi:"SPBC216.05.1:pep"	intact:EBI-768448|uniprotkb:Q09754|ensemblfungi:"SPBC342.05.1:pep"	psi-mi:rad3_schpo(display_long)|uniprotkb:DNA repair protein rad3(gene name synonym)|uniprotkb:rad3(gene name)|psi-mi:rad3(display_short)|uniprotkb:SPBC216.05(orf name)	psi-mi:rhp9_schpo(display_long)|uniprotkb:crb2(gene name)|psi-mi:crb2(display_short)|uniprotkb:Checkpoint mediator protein crb2(gene name synonym)|uniprotkb:Cut5-repeat binding protein 2(gene name synonym)|uniprotkb:RAD9 protein homolog(gene name synonym)|uniprotkb:rhp9(gene name synonym)|uniprotkb:SPBC342.05(orf name)	psi-mi:"MI:0096"(pull down)	Mochida et al. (2004)	pubmed:14739927	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153472	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_595357.1|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR018936|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR014009(PIK-related kinase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012993(UME)|interpro:IPR036940|ensemblfungi:SPBC216.05(gene)|ensemblfungi:SPBC216.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0033315"(meiotic G2/MI DNA replication checkpoint signaling)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070310"(ATR-ATRIP complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072371"("histone kinase activity (H2A-S121 specific)")|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1904514"(positive regulation of initiation of premeiotic DNA replication)	rcsb pdb:4BU0|rcsb pdb:4BU1|refseq:NP_596748.1|interpro:IPR001357(BRCT)|rcsb pdb:2FHD|rcsb pdb:2VXB|rcsb pdb:2VXC|interpro:IPR036420|interpro:IPR041297|reactome:R-SPO-3232118|ensemblfungi:SPBC342.05(gene)|ensemblfungi:SPBC342.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140463"(chromatin-protein adaptor)	-	-	-	figure legend:Fig. 4F|comment:This interaction is reduced following prior UV irradiation of cells expressing rhp9/crb2.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/02	2014/10/16	rogid:6qu9ae5L6QdgpHZvEfWksxbBvpo284812	rogid:oHsEyMA31ahL6m7wLIQUp6TLagk284812	intact-crc:519295FB2DFAA316|rigid:d41kRt2bExVW86NLovYTSEOFpOk	false	glutathione s tranferase tag:n-n	ha tag:n-n|sufficient binding region:535-778	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32372	uniprotkb:P87074	intact:EBI-768521|ensemblfungi:"SPAC23C4.18c.1:pep"	intact:EBI-768448|uniprotkb:Q09754|ensemblfungi:"SPBC342.05.1:pep"	psi-mi:rad4_schpo(display_long)|uniprotkb:Protein cut5(gene name synonym)|uniprotkb:P74(gene name synonym)|uniprotkb:rad4(gene name)|psi-mi:rad4(display_short)|uniprotkb:cut5(gene name synonym)|uniprotkb:SPAC23C4.18c(orf name)	psi-mi:rhp9_schpo(display_long)|uniprotkb:crb2(gene name)|psi-mi:crb2(display_short)|uniprotkb:Checkpoint mediator protein crb2(gene name synonym)|uniprotkb:Cut5-repeat binding protein 2(gene name synonym)|uniprotkb:RAD9 protein homolog(gene name synonym)|uniprotkb:rhp9(gene name synonym)|uniprotkb:SPBC342.05(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Mochida et al. (2004)	pubmed:14739927	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153498	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4BMC|rcsb pdb:4BMD|rcsb pdb:4BU0|rcsb pdb:4BU1|refseq:NP_593190.1|interpro:IPR001357(BRCT)|interpro:IPR036420|rcsb pdb:6HM3|rcsb pdb:6HM4|ensemblfungi:SPAC23C4.18c(gene)|ensemblfungi:SPAC23C4.18c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0072686"(mitotic spindle)	rcsb pdb:4BU0|rcsb pdb:4BU1|refseq:NP_596748.1|interpro:IPR001357(BRCT)|rcsb pdb:2FHD|rcsb pdb:2VXB|rcsb pdb:2VXC|interpro:IPR036420|interpro:IPR041297|reactome:R-SPO-3232118|ensemblfungi:SPBC342.05(gene)|ensemblfungi:SPBC342.05.1(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140463"(chromatin-protein adaptor)	-	-	-	figure legend:Fig. 5D|comment:This interaction is enhanced following UV irradiation.	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/11/02	2014/10/16	rogid:6rgRCxmDXZyDmbaoeIIPhfJvu8g284812	rogid:oHsEyMA31ahL6m7wLIQUp6TLagk284812	intact-crc:AB00BBEE7C8645DA|rigid:lrJDHwpsQO466gBHIWdMF0UIsBg	false	-	calmodulin binding peptide plus protein a tag:n-n	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)