#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BV57 uniprotkb:P50281 intact:EBI-992807|uniprotkb:Q53HW3|uniprotkb:Q53QD3|uniprotkb:Q57YV7|uniprotkb:Q68CK2|uniprotkb:Q6ZSF7|uniprotkb:Q7Z512|uniprotkb:Q96P85|uniprotkb:Q9NV57|ensembl:ENSP00000333666|uniprotkb:D6W4Y3 intact:EBI-992788|uniprotkb:Q6GSF3|uniprotkb:Q92678|uniprotkb:A8K5L0|ensembl:ENSP00000308208 psi-mi:mtnd_human(display_long)|uniprotkb:Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1(gene name synonym)|uniprotkb:ADI1(gene name)|psi-mi:ADI1(display_short)|uniprotkb:MTCBP1(gene name synonym)|uniprotkb:"Acireductone dioxygenase (Fe(2+)-requiring)"(gene name synonym)|uniprotkb:Submergence-induced protein-like factor(gene name synonym)|uniprotkb:HMFT1638(orf name) psi-mi:mmp14_human(display_long)|uniprotkb:Membrane-type matrix metalloproteinase 1(gene name synonym)|uniprotkb:Membrane-type-1 matrix metalloproteinase(gene name synonym)|uniprotkb:MMP-X1(gene name synonym)|uniprotkb:MMP14(gene name)|psi-mi:MMP14(display_short) psi-mi:"MI:0018"(two hybrid) Uekita et al. (2004) imex:IM-14445|pubmed:14718544 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-992803|imex:IM-14445-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293006.1|ensembl:ENSG00000182551(gene)|ensembl:ENST00000327435(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0010309"("acireductone dioxygenase [iron(II)-requiring] activity")|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|interpro:IPR004313(Acireductone dioxygenase, ARD)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027496|rcsb pdb:4QGN|rcsb pdb:7JXG|reactome:R-HSA-1237112|refseq:NP_060739.2 ensembl:ENST00000311852(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010831"(positive regulation of myotube differentiation)|ensembl:ENSG00000157227(gene)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016485"(protein processing)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031638"(zymogen activation)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0044354"(macropinosome)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048870"(cell motility)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060322"(head development)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1990834"(response to odorant)|interpro:IPR000585(Hemopexin)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR021805|interpro:IPR024079|interpro:IPR033739|interpro:IPR036365|interpro:IPR036366|interpro:IPR036375|mint:P50281|rcsb pdb:1BQQ|rcsb pdb:1BUV|rcsb pdb:2MQS|rcsb pdb:3MA2|rcsb pdb:3X23|rcsb pdb:4P3C|rcsb pdb:4P3D|rcsb pdb:4QXU|rcsb pdb:5H0U|rcsb pdb:6CLZ|rcsb pdb:6CM1|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|rcsb pdb:3C7X|refseq:NP_004986.1|dip:DIP-35111N psi-mi:"MI:0469"(intact) - - figure legend:none|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/08/21 2014/10/16 rogid:cXi20f9iVMmoZm0Ez2BUWsdUP1A9606 rogid:x2H2pYgnfBvYy7Stikq3uk+ihhw9606 intact-crc:92B8B6667914278D|rigid:N00jt/ox8vdBVLn6eMWF5/Vk8XU false - binding-associated region:563-582 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P50281 uniprotkb:Q9BV57 intact:EBI-992788|uniprotkb:Q6GSF3|uniprotkb:Q92678|uniprotkb:A8K5L0|ensembl:ENSP00000308208 intact:EBI-992807|uniprotkb:Q53HW3|uniprotkb:Q53QD3|uniprotkb:Q57YV7|uniprotkb:Q68CK2|uniprotkb:Q6ZSF7|uniprotkb:Q7Z512|uniprotkb:Q96P85|uniprotkb:Q9NV57|ensembl:ENSP00000333666|uniprotkb:D6W4Y3 psi-mi:mmp14_human(display_long)|uniprotkb:Membrane-type matrix metalloproteinase 1(gene name synonym)|uniprotkb:Membrane-type-1 matrix metalloproteinase(gene name synonym)|uniprotkb:MMP-X1(gene name synonym)|uniprotkb:MMP14(gene name)|psi-mi:MMP14(display_short) psi-mi:mtnd_human(display_long)|uniprotkb:Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1(gene name synonym)|uniprotkb:ADI1(gene name)|psi-mi:ADI1(display_short)|uniprotkb:MTCBP1(gene name synonym)|uniprotkb:"Acireductone dioxygenase (Fe(2+)-requiring)"(gene name synonym)|uniprotkb:Submergence-induced protein-like factor(gene name synonym)|uniprotkb:HMFT1638(orf name) psi-mi:"MI:0096"(pull down) Uekita et al. (2004) imex:IM-14445|pubmed:14718544 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-992851|imex:IM-14445-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000311852(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010831"(positive regulation of myotube differentiation)|ensembl:ENSG00000157227(gene)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016485"(protein processing)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031638"(zymogen activation)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0044354"(macropinosome)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048870"(cell motility)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060322"(head development)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1990834"(response to odorant)|interpro:IPR000585(Hemopexin)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR021805|interpro:IPR024079|interpro:IPR033739|interpro:IPR036365|interpro:IPR036366|interpro:IPR036375|mint:P50281|rcsb pdb:1BQQ|rcsb pdb:1BUV|rcsb pdb:2MQS|rcsb pdb:3MA2|rcsb pdb:3X23|rcsb pdb:4P3C|rcsb pdb:4P3D|rcsb pdb:4QXU|rcsb pdb:5H0U|rcsb pdb:6CLZ|rcsb pdb:6CM1|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|rcsb pdb:3C7X|refseq:NP_004986.1|dip:DIP-35111N refseq:NP_001293006.1|ensembl:ENSG00000182551(gene)|ensembl:ENST00000327435(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0010309"("acireductone dioxygenase [iron(II)-requiring] activity")|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|interpro:IPR004313(Acireductone dioxygenase, ARD)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027496|rcsb pdb:4QGN|rcsb pdb:7JXG|reactome:R-HSA-1237112|refseq:NP_060739.2 psi-mi:"MI:0469"(intact) - - figure legend:3A|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/08/21 2014/10/16 rogid:x2H2pYgnfBvYy7Stikq3uk+ihhw9606 rogid:cXi20f9iVMmoZm0Ez2BUWsdUP1A9606 intact-crc:81BEB82AF2A146B8|rigid:N00jt/ox8vdBVLn6eMWF5/Vk8XU false his tag:?-?|binding-associated region:563-582 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BV57 uniprotkb:P50281 intact:EBI-992807|uniprotkb:Q53HW3|uniprotkb:Q53QD3|uniprotkb:Q57YV7|uniprotkb:Q68CK2|uniprotkb:Q6ZSF7|uniprotkb:Q7Z512|uniprotkb:Q96P85|uniprotkb:Q9NV57|ensembl:ENSP00000333666|uniprotkb:D6W4Y3 intact:EBI-992788|uniprotkb:Q6GSF3|uniprotkb:Q92678|uniprotkb:A8K5L0|ensembl:ENSP00000308208 psi-mi:mtnd_human(display_long)|uniprotkb:Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1(gene name synonym)|uniprotkb:ADI1(gene name)|psi-mi:ADI1(display_short)|uniprotkb:MTCBP1(gene name synonym)|uniprotkb:"Acireductone dioxygenase (Fe(2+)-requiring)"(gene name synonym)|uniprotkb:Submergence-induced protein-like factor(gene name synonym)|uniprotkb:HMFT1638(orf name) psi-mi:mmp14_human(display_long)|uniprotkb:Membrane-type matrix metalloproteinase 1(gene name synonym)|uniprotkb:Membrane-type-1 matrix metalloproteinase(gene name synonym)|uniprotkb:MMP-X1(gene name synonym)|uniprotkb:MMP14(gene name)|psi-mi:MMP14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Uekita et al. (2004) imex:IM-14445|pubmed:14718544 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-992868|imex:IM-14445-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293006.1|ensembl:ENSG00000182551(gene)|ensembl:ENST00000327435(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0010309"("acireductone dioxygenase [iron(II)-requiring] activity")|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|interpro:IPR004313(Acireductone dioxygenase, ARD)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027496|rcsb pdb:4QGN|rcsb pdb:7JXG|reactome:R-HSA-1237112|refseq:NP_060739.2 ensembl:ENST00000311852(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010831"(positive regulation of myotube differentiation)|ensembl:ENSG00000157227(gene)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016485"(protein processing)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031638"(zymogen activation)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0044354"(macropinosome)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048870"(cell motility)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060322"(head development)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1990834"(response to odorant)|interpro:IPR000585(Hemopexin)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR021805|interpro:IPR024079|interpro:IPR033739|interpro:IPR036365|interpro:IPR036366|interpro:IPR036375|mint:P50281|rcsb pdb:1BQQ|rcsb pdb:1BUV|rcsb pdb:2MQS|rcsb pdb:3MA2|rcsb pdb:3X23|rcsb pdb:4P3C|rcsb pdb:4P3D|rcsb pdb:4QXU|rcsb pdb:5H0U|rcsb pdb:6CLZ|rcsb pdb:6CM1|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|rcsb pdb:3C7X|refseq:NP_004986.1|dip:DIP-35111N psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ht1080)|taxid:9606(Homo sapiens HT1080 fribrosarcoma cell line) - 2006/08/21 2014/10/16 rogid:cXi20f9iVMmoZm0Ez2BUWsdUP1A9606 rogid:x2H2pYgnfBvYy7Stikq3uk+ihhw9606 intact-crc:F1D7B8599CAE1195|rigid:N00jt/ox8vdBVLn6eMWF5/Vk8XU false - flag tag:?-?|binding-associated region:563-582 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P50281 uniprotkb:Q9BV57 intact:EBI-992788|uniprotkb:Q6GSF3|uniprotkb:Q92678|uniprotkb:A8K5L0|ensembl:ENSP00000308208 intact:EBI-992807|uniprotkb:Q53HW3|uniprotkb:Q53QD3|uniprotkb:Q57YV7|uniprotkb:Q68CK2|uniprotkb:Q6ZSF7|uniprotkb:Q7Z512|uniprotkb:Q96P85|uniprotkb:Q9NV57|ensembl:ENSP00000333666|uniprotkb:D6W4Y3 psi-mi:mmp14_human(display_long)|uniprotkb:Membrane-type matrix metalloproteinase 1(gene name synonym)|uniprotkb:Membrane-type-1 matrix metalloproteinase(gene name synonym)|uniprotkb:MMP-X1(gene name synonym)|uniprotkb:MMP14(gene name)|psi-mi:MMP14(display_short) psi-mi:mtnd_human(display_long)|uniprotkb:Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1(gene name synonym)|uniprotkb:ADI1(gene name)|psi-mi:ADI1(display_short)|uniprotkb:MTCBP1(gene name synonym)|uniprotkb:"Acireductone dioxygenase (Fe(2+)-requiring)"(gene name synonym)|uniprotkb:Submergence-induced protein-like factor(gene name synonym)|uniprotkb:HMFT1638(orf name) psi-mi:"MI:0663"(confocal microscopy) Uekita et al. (2004) imex:IM-14445|pubmed:14718544 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-992885|imex:IM-14445-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000311852(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010831"(positive regulation of myotube differentiation)|ensembl:ENSG00000157227(gene)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016485"(protein processing)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031638"(zymogen activation)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0044354"(macropinosome)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048870"(cell motility)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060322"(head development)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1990834"(response to odorant)|interpro:IPR000585(Hemopexin)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR021805|interpro:IPR024079|interpro:IPR033739|interpro:IPR036365|interpro:IPR036366|interpro:IPR036375|mint:P50281|rcsb pdb:1BQQ|rcsb pdb:1BUV|rcsb pdb:2MQS|rcsb pdb:3MA2|rcsb pdb:3X23|rcsb pdb:4P3C|rcsb pdb:4P3D|rcsb pdb:4QXU|rcsb pdb:5H0U|rcsb pdb:6CLZ|rcsb pdb:6CM1|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|rcsb pdb:3C7X|refseq:NP_004986.1|dip:DIP-35111N refseq:NP_001293006.1|ensembl:ENSG00000182551(gene)|ensembl:ENST00000327435(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0010309"("acireductone dioxygenase [iron(II)-requiring] activity")|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|interpro:IPR004313(Acireductone dioxygenase, ARD)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027496|rcsb pdb:4QGN|rcsb pdb:7JXG|reactome:R-HSA-1237112|refseq:NP_060739.2 go:"GO:0005886"(plasma membrane) - - figure legend:3C|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ht1080)|taxid:9606(Homo sapiens HT1080 fribrosarcoma cell line) - 2006/08/21 2014/10/16 rogid:x2H2pYgnfBvYy7Stikq3uk+ihhw9606 rogid:cXi20f9iVMmoZm0Ez2BUWsdUP1A9606 intact-crc:7F033A6D26136E75|rigid:N00jt/ox8vdBVLn6eMWF5/Vk8XU false flag tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)