#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6STE5-1 uniprotkb:P37231 intact:EBI-488506|ensembl:ENSP00000262188 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:q6ste5-1(display_long)|uniprotkb:BAF60C2(isoform synonym)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0096"(pull down) Debril et al. (2004) imex:IM-14404|pubmed:14701856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-926247|imex:IM-14404-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000082014(gene)|ensembl:ENST00000262188(transcript)|intact:EBI-465496(smrd3_human) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707 psi-mi:"MI:0469"(intact) - - comment:Interaction occurred both in the absence as well as in the presence of 1 �M rosiglitazone.|figure legend:4|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/10 2014/10/16 rogid:fCKGyz4ZneKj5VHia17wdMq6neI9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 intact-crc:EDC38B3F1702F1A7|rigid:hWAgTrgFY/DZWuSyjV/rw7jabl4 false glutathione s tranferase tag:n-n|sufficient binding region:1-194 his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6STE5-2 uniprotkb:P37231 intact:EBI-488511|ensembl:ENSP00000349254|ensembl:ENSP00000376558 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:q6ste5-2(display_long)|uniprotkb:BAF60C1(isoform synonym)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0096"(pull down) Debril et al. (2004) imex:IM-14404|pubmed:14701856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1008737|imex:IM-14404-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000082014(gene)|ensembl:ENST00000356800(transcript)|ensembl:ENST00000392811(transcript)|intact:EBI-465496(smrd3_human)|uniprotkb:Q6STE5-2(isoform-parent) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707 psi-mi:"MI:0469"(intact) - - comment:Interaction occurred both in the absence as well as in the presence of 1 �M rosiglitazone.|figure legend:4|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/10 2014/10/16 rogid:iLs7BW7gPLRL1tkJUc9YaKXIhKU9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 intact-crc:A8183803670D5F1B|rigid:6HpMM3CNFbpgUDr+abO+VTFTes0 false glutathione s tranferase tag:n-n his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6STE5-1 uniprotkb:P37231-2 intact:EBI-488506|ensembl:ENSP00000262188 intact:EBI-781416|intact:EBI-7134554|intact:MINT-5209793|intact:EBI-7134312|intact:EBI-7134260|intact:EBI-7134576 psi-mi:q6ste5-1(display_long)|uniprotkb:BAF60C2(isoform synonym)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:p37231-2(display_long)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:"PPARgamma1(wt)"(isoform synonym) psi-mi:"MI:0018"(two hybrid) Debril et al. (2004) imex:IM-14404|pubmed:14701856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-926261|imex:IM-14404-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000082014(gene)|ensembl:ENST00000262188(transcript)|intact:EBI-465496(smrd3_human) intact:EBI-781384(pparg_human)|uniprotkb:P37231-2(isoform-parent) psi-mi:"MI:0469"(intact) - - dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/04/10 2014/10/16 rogid:fCKGyz4ZneKj5VHia17wdMq6neI9606 rogid:es4vOaUCjPGHBZi7iHj0MKNkcKI9606 intact-crc:D873AF99483561CC|rigid:xY1NkocRlcvurKE2EqjHblzu7vk false - sufficient binding region:179-477 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6STE5-2 uniprotkb:P37231 intact:EBI-488511|ensembl:ENSP00000349254|ensembl:ENSP00000376558 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:q6ste5-2(display_long)|uniprotkb:BAF60C1(isoform synonym)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0096"(pull down) Debril et al. (2004) imex:IM-14404|pubmed:14701856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1008535|imex:IM-14404-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000082014(gene)|ensembl:ENST00000356800(transcript)|ensembl:ENST00000392811(transcript)|intact:EBI-465496(smrd3_human)|uniprotkb:Q6STE5-2(isoform-parent) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707 psi-mi:"MI:0469"(intact) - - comment:Interaction occurred both in the absence as well as in the presence of 1 �M rosiglitazone.|figure legend:4|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/10 2014/10/16 rogid:iLs7BW7gPLRL1tkJUc9YaKXIhKU9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 intact-crc:F3E03A53E4D50BDC|rigid:6HpMM3CNFbpgUDr+abO+VTFTes0 false glutathione s tranferase tag:n-n 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6STE5-1 uniprotkb:P37231 intact:EBI-488506|ensembl:ENSP00000262188 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:q6ste5-1(display_long)|uniprotkb:BAF60C2(isoform synonym)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0096"(pull down) Debril et al. (2004) imex:IM-14404|pubmed:14701856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1008779|imex:IM-14404-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000082014(gene)|ensembl:ENST00000262188(transcript)|intact:EBI-465496(smrd3_human) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707 psi-mi:"MI:0469"(intact) - - comment:Interaction occurred both in the absence as well as in the presence of 1 �M rosiglitazone.|figure legend:4|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/10 2014/10/16 rogid:fCKGyz4ZneKj5VHia17wdMq6neI9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 intact-crc:6B2C6E89A02D7BB7|rigid:hWAgTrgFY/DZWuSyjV/rw7jabl4 false sufficient binding region:1-194|glutathione s tranferase tag:n-n his tag:?-?|35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37231 uniprotkb:Q6STE5-1 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 intact:EBI-488506|ensembl:ENSP00000262188 psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:q6ste5-1(display_long)|uniprotkb:BAF60C2(isoform synonym)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:"MI:0096"(pull down) Debril et al. (2004) imex:IM-14404|pubmed:14701856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1008857|imex:IM-14404-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707 ensembl:ENSG00000082014(gene)|ensembl:ENST00000262188(transcript)|intact:EBI-465496(smrd3_human) psi-mi:"MI:0469"(intact) - - comment:Interaction occurred both in the absence as well as in the presence of 1 �M rosiglitazone.|figure legend:4D|comment:N terminal region interacted better than 204-507 region.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/10 2014/10/16 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rogid:fCKGyz4ZneKj5VHia17wdMq6neI9606 intact-crc:5A4828DB8688A92D|rigid:hWAgTrgFY/DZWuSyjV/rw7jabl4 false sufficient binding region:?-?|sufficient binding region:1-129|glutathione s tranferase tag:n-n 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P37231 uniprotkb:Q6STE5-2 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 intact:EBI-488511|ensembl:ENSP00000349254|ensembl:ENSP00000376558 psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:q6ste5-2(display_long)|uniprotkb:BAF60C1(isoform synonym)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:"MI:0096"(pull down) Debril et al. (2004) imex:IM-14404|pubmed:14701856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1008884|imex:IM-14404-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707 ensembl:ENSG00000082014(gene)|ensembl:ENST00000356800(transcript)|ensembl:ENST00000392811(transcript)|intact:EBI-465496(smrd3_human)|uniprotkb:Q6STE5-2(isoform-parent) psi-mi:"MI:0469"(intact) - - comment:Interaction occurred both in the absence as well as in the presence of 1 �M rosiglitazone.|figure legend:4D|comment:N terminal region interacted better than 204-507 region.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/10 2014/10/16 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 rogid:iLs7BW7gPLRL1tkJUc9YaKXIhKU9606 intact-crc:BB523D1AEC1E9CB8|rigid:6HpMM3CNFbpgUDr+abO+VTFTes0 false glutathione s tranferase tag:n-n|sufficient binding region:?-?|sufficient binding region:1-129 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08580 uniprotkb:Q6STE5-1 intact:EBI-1008937|uniprotkb:B2RRU9|uniprotkb:Q3U110|ensembl:ENSMUSP00000025906 intact:EBI-488506|ensembl:ENSP00000262188 psi-mi:err1_mouse(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:Esrra(gene name)|psi-mi:Esrra(display_short)|uniprotkb:Err1(gene name synonym)|uniprotkb:Estrra(gene name synonym)|uniprotkb:Nr3b1(gene name synonym) psi-mi:q6ste5-1(display_long)|uniprotkb:BAF60C2(isoform synonym)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:"MI:0096"(pull down) Debril et al. (2004) imex:IM-14404|pubmed:14701856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1008928|imex:IM-14404-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031979.2|ensembl:ENSMUSG00000024955(gene)|ensembl:ENSMUST00000025906(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|reactome:R-MMU-383280 ensembl:ENSG00000082014(gene)|ensembl:ENST00000262188(transcript)|intact:EBI-465496(smrd3_human) psi-mi:"MI:0469"(intact) - - figure legend:5|comment:"Other receptors were also shown to interact with hBAF60c1 and hBAF60c2: RXR, ROR alpha1, LRH1 SF1, SREBP1a, FXR, c-Jun and PBX1"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/10 2014/10/16 rogid:DM98DOmkn3+W5S5lHfiR17z8Cr010090 rogid:fCKGyz4ZneKj5VHia17wdMq6neI9606 intact-crc:1E42CD42C56821E9|rigid:gVlRjpH5H0bV6MmsRe5u1STGGLE false 35s radiolabel:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08580 uniprotkb:Q6STE5-2 intact:EBI-1008937|uniprotkb:B2RRU9|uniprotkb:Q3U110|ensembl:ENSMUSP00000025906 intact:EBI-488511|ensembl:ENSP00000349254|ensembl:ENSP00000376558 psi-mi:err1_mouse(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:Esrra(gene name)|psi-mi:Esrra(display_short)|uniprotkb:Err1(gene name synonym)|uniprotkb:Estrra(gene name synonym)|uniprotkb:Nr3b1(gene name synonym) psi-mi:q6ste5-2(display_long)|uniprotkb:BAF60C1(isoform synonym)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:"MI:0096"(pull down) Debril et al. (2004) imex:IM-14404|pubmed:14701856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1008980|imex:IM-14404-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031979.2|ensembl:ENSMUSG00000024955(gene)|ensembl:ENSMUST00000025906(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|reactome:R-MMU-383280 ensembl:ENSG00000082014(gene)|ensembl:ENST00000356800(transcript)|ensembl:ENST00000392811(transcript)|intact:EBI-465496(smrd3_human)|uniprotkb:Q6STE5-2(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:5|comment:"Other receptors were also shown to interact with hBAF60c1 and hBAF60c2: RXR, ROR alpha1, LRH1 SF1, SREBP1a, FXR, c-Jun and PBX1"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/10 2014/10/16 rogid:DM98DOmkn3+W5S5lHfiR17z8Cr010090 rogid:iLs7BW7gPLRL1tkJUc9YaKXIhKU9606 intact-crc:23B3B32F1D3EEC02|rigid:CPPgSuzMo7IgR5gaWmxJkqgCl/Y false 35s radiolabel:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51532 uniprotkb:P37231 intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Debril et al. (2004) imex:IM-14404|pubmed:14701856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1008553|imex:IM-14404-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665 refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707 psi-mi:"MI:0469"(intact) - - figure legend:4E|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/04/10 2014/10/16 rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 intact-crc:28C8DBB8CDC1CA2D|rigid:FkZrYgTmfWEfJ8kQa44o9Wo88Wc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P51531 uniprotkb:Q6STE5-1 intact:EBI-679562|uniprotkb:B1ALG3|uniprotkb:B1ALG4|uniprotkb:D3DRH4|uniprotkb:D3DRH5|ensembl:ENSP00000265773|ensembl:ENSP00000371638 intact:EBI-488506|ensembl:ENSP00000262188 psi-mi:smca2_human(display_long)|uniprotkb:ATP-dependent helicase SMARCA2(gene name synonym)|uniprotkb:SNF2-alpha(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2(gene name synonym)|uniprotkb:SMARCA2(gene name)|psi-mi:SMARCA2(display_short)|uniprotkb:BRM(gene name synonym)|uniprotkb:SNF2A(gene name synonym)|uniprotkb:SNF2L2(gene name synonym)|uniprotkb:BAF190B(gene name synonym)|uniprotkb:Protein brahma homolog(gene name synonym)|uniprotkb:BRG1-associated factor 190B(gene name synonym) psi-mi:q6ste5-1(display_long)|uniprotkb:BAF60C2(isoform synonym)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Debril et al. (2004) imex:IM-14404|pubmed:14701856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1008558|imex:IM-14404-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003061.3|refseq:NP_620614.2|refseq:NP_001276325.1|refseq:NP_001276326.1|dip:DIP-29005N|ensembl:ENSG00000080503(gene)|ensembl:ENST00000349721(transcript)|ensembl:ENST00000382203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030088|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51531|rcsb pdb:2DAT|rcsb pdb:4QY4|rcsb pdb:5DKC|rcsb pdb:5DKH|rcsb pdb:6EG2|rcsb pdb:6EG3|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HAZ|reactome:R-HSA-3214858|reactome:R-HSA-8939243 ensembl:ENSG00000082014(gene)|ensembl:ENST00000262188(transcript)|intact:EBI-465496(smrd3_human) psi-mi:"MI:0469"(intact) - - figure legend:4E|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/04/10 2014/10/16 rogid:DmQot4h4SmtqmUGBgF5ictTah289606 rogid:fCKGyz4ZneKj5VHia17wdMq6neI9606 intact-crc:BD23327032BF50D4|rigid:gy+PfIk6pU/DMtS6VFaX700zJyo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)