#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P40381 uniprotkb:P50582 intact:EBI-926939|ensemblfungi:"SPAC664.01c.1:pep" intact:EBI-908476|uniprotkb:O94678|ensemblfungi:"SPBC776.12c.1:pep" psi-mi:swi6_schpo(display_long)|uniprotkb:swi6(gene name)|psi-mi:swi6(display_short)|uniprotkb:SPAC664.01c(orf name)|uniprotkb:SPAC824.10c(orf name) psi-mi:hsk1_schpo(display_long)|uniprotkb:hsk1(gene name)|psi-mi:hsk1(display_short)|uniprotkb:SPBC776.12c(orf name)|uniprotkb:Minichromosome maintenance protein kinase(gene name synonym)|uniprotkb:Cdc7-related kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bailis et al. (2003) pubmed:14625560 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1126967 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593449.1|dip:DIP-35736N|reactome:R-SPO-73772|reactome:R-SPO-983231|ensemblfungi:SPAC664.01c(gene)|ensemblfungi:SPAC664.01c.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006325"(chromatin organization)|go:"GO:0007533"(mating type switching)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0033696"(heterochromatin boundary formation)|go:"GO:0034507"(chromosome, centromeric outer repeat region)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044820"(mitotic telomere tethering at nuclear periphery)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1990342"(heterochromatin island)|go:"GO:1990758"(mitotic sister chromatid biorientation)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1E0B|rcsb pdb:2RSO refseq:NP_596328.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC776.12c(gene)|ensemblfungi:SPBC776.12c.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010620"(negative regulation of transcription by transcription factor catabolism)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902975"(mitotic DNA replication initiation) - crc64:F505CC8AC5E75EAB - figure legend:Fig 1A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/10/25 2014/10/16 rogid:EEISpq3oLJ9jyNp6870DB1Z3xCY284812 rogid:vu2hPDUtV3VzgfiEdhiYtw5WUpU284812 intact-crc:069B7F1CC6316EDB|rigid:TVJJkWfJxyxaUdnE7aOq8/tdjgs false - ha tag:c-c - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P40381 uniprotkb:O59836 intact:EBI-926939|ensemblfungi:"SPAC664.01c.1:pep" intact:EBI-908382|ensemblfungi:"SPCC550.13.1:pep" psi-mi:swi6_schpo(display_long)|uniprotkb:swi6(gene name)|psi-mi:swi6(display_short)|uniprotkb:SPAC664.01c(orf name)|uniprotkb:SPAC824.10c(orf name) psi-mi:him1_schpo(display_long)|uniprotkb:SPCC550.13(orf name)|uniprotkb:him1(gene name)|psi-mi:him1(display_short)|uniprotkb:dfp1(gene name synonym)|uniprotkb:rad35(gene name synonym)|uniprotkb:DNA repair protein rad35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bailis et al. (2003) pubmed:14625560 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1127206 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593449.1|dip:DIP-35736N|reactome:R-SPO-73772|reactome:R-SPO-983231|ensemblfungi:SPAC664.01c(gene)|ensemblfungi:SPAC664.01c.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006325"(chromatin organization)|go:"GO:0007533"(mating type switching)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0033696"(heterochromatin boundary formation)|go:"GO:0034507"(chromosome, centromeric outer repeat region)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044820"(mitotic telomere tethering at nuclear periphery)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1990342"(heterochromatin island)|go:"GO:1990758"(mitotic sister chromatid biorientation)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1E0B|rcsb pdb:2RSO refseq:NP_588105.1|interpro:IPR001357(BRCT)|interpro:IPR013939(Regulatory subunit Dfp1/Him1, central region)|interpro:IPR006572(Zinc finger, DBF-type)|interpro:IPR038545|interpro:IPR036420|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPCC550.13(gene)|ensemblfungi:SPCC550.13.1(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0048478"(replication fork protection)|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1903466"(regulation of mitotic DNA replication initiation)|go:"GO:1903468"(positive regulation of DNA replication initiation) - crc64:F505CC8AC5E75EAB - figure legend:Fig 1B, S1E|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/10/25 2014/10/16 rogid:EEISpq3oLJ9jyNp6870DB1Z3xCY284812 rogid:jqgB/+ji7/8agWCnJgorOov7kmA284812 intact-crc:80C97BCDD93C8BD6|rigid:wgs6QzyjJkGahUc6f/GHff/tt5M false - myc tag:c-c|necessary binding region:377-545 - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O59836 uniprotkb:P40381 intact:EBI-908382|ensemblfungi:"SPCC550.13.1:pep" intact:EBI-926939|ensemblfungi:"SPAC664.01c.1:pep" psi-mi:him1_schpo(display_long)|uniprotkb:SPCC550.13(orf name)|uniprotkb:him1(gene name)|psi-mi:him1(display_short)|uniprotkb:dfp1(gene name synonym)|uniprotkb:rad35(gene name synonym)|uniprotkb:DNA repair protein rad35(gene name synonym) psi-mi:swi6_schpo(display_long)|uniprotkb:swi6(gene name)|psi-mi:swi6(display_short)|uniprotkb:SPAC664.01c(orf name)|uniprotkb:SPAC824.10c(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bailis et al. (2003) pubmed:14625560 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1131844 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_588105.1|interpro:IPR001357(BRCT)|interpro:IPR013939(Regulatory subunit Dfp1/Him1, central region)|interpro:IPR006572(Zinc finger, DBF-type)|interpro:IPR038545|interpro:IPR036420|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPCC550.13(gene)|ensemblfungi:SPCC550.13.1(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0048478"(replication fork protection)|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1903466"(regulation of mitotic DNA replication initiation)|go:"GO:1903468"(positive regulation of DNA replication initiation) refseq:NP_593449.1|dip:DIP-35736N|reactome:R-SPO-73772|reactome:R-SPO-983231|ensemblfungi:SPAC664.01c(gene)|ensemblfungi:SPAC664.01c.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006325"(chromatin organization)|go:"GO:0007533"(mating type switching)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0033696"(heterochromatin boundary formation)|go:"GO:0034507"(chromosome, centromeric outer repeat region)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044820"(mitotic telomere tethering at nuclear periphery)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1990342"(heterochromatin island)|go:"GO:1990758"(mitotic sister chromatid biorientation)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1E0B|rcsb pdb:2RSO - - crc64:F505CC8AC5E75EAB figure legend:Fig S1A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/10/25 2014/10/16 rogid:jqgB/+ji7/8agWCnJgorOov7kmA284812 rogid:EEISpq3oLJ9jyNp6870DB1Z3xCY284812 intact-crc:E4F06A346EF47129|rigid:wgs6QzyjJkGahUc6f/GHff/tt5M false necessary binding region:377-545|ha tag:c-c - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P40381 uniprotkb:P50582 intact:EBI-926939|ensemblfungi:"SPAC664.01c.1:pep" intact:EBI-908476|uniprotkb:O94678|ensemblfungi:"SPBC776.12c.1:pep" psi-mi:swi6_schpo(display_long)|uniprotkb:swi6(gene name)|psi-mi:swi6(display_short)|uniprotkb:SPAC664.01c(orf name)|uniprotkb:SPAC824.10c(orf name) psi-mi:hsk1_schpo(display_long)|uniprotkb:hsk1(gene name)|psi-mi:hsk1(display_short)|uniprotkb:SPBC776.12c(orf name)|uniprotkb:Minichromosome maintenance protein kinase(gene name synonym)|uniprotkb:Cdc7-related kinase(gene name synonym) psi-mi:"MI:0420"(kinase homogeneous time resolved fluorescence) Bailis et al. (2003) pubmed:14625560 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-1128421 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593449.1|dip:DIP-35736N|reactome:R-SPO-73772|reactome:R-SPO-983231|ensemblfungi:SPAC664.01c(gene)|ensemblfungi:SPAC664.01c.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006325"(chromatin organization)|go:"GO:0007533"(mating type switching)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0033696"(heterochromatin boundary formation)|go:"GO:0034507"(chromosome, centromeric outer repeat region)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044820"(mitotic telomere tethering at nuclear periphery)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1990342"(heterochromatin island)|go:"GO:1990758"(mitotic sister chromatid biorientation)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1E0B|rcsb pdb:2RSO refseq:NP_596328.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC776.12c(gene)|ensemblfungi:SPBC776.12c.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010620"(negative regulation of transcription by transcription factor catabolism)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902975"(mitotic DNA replication initiation) - crc64:F505CC8AC5E75EAB - figure legend:Fig 1D|resulting-ptm:Phosphorylation of swi6.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/10/25 2014/10/16 rogid:EEISpq3oLJ9jyNp6870DB1Z3xCY284812 rogid:vu2hPDUtV3VzgfiEdhiYtw5WUpU284812 intact-crc:C80F66BAE284166F|rigid:TVJJkWfJxyxaUdnE7aOq8/tdjgs false his tag:n-n mutation decreasing interaction:314-314|ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O13816 uniprotkb:P40381 intact:EBI-1131314|uniprotkb:Q38G50|uniprotkb:Q9US16|ensemblfungi:"SPAC17H9.20.1:pep" intact:EBI-926939|ensemblfungi:"SPAC664.01c.1:pep" psi-mi:scc3_schpo(display_long)|uniprotkb:SCC3 homolog(gene name synonym)|uniprotkb:psc3(gene name)|psi-mi:psc3(display_short)|uniprotkb:SPAC17H9.20(orf name)|uniprotkb:SPAC607.01(orf name) psi-mi:swi6_schpo(display_long)|uniprotkb:swi6(gene name)|psi-mi:swi6(display_short)|uniprotkb:SPAC664.01c(orf name)|uniprotkb:SPAC824.10c(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bailis et al. (2003) pubmed:14625560 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1131298 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPAC17H9.20(gene)|ensemblfungi:SPAC17H9.20.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0030892"(mitotic cohesin complex)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:0061780"(mitotic cohesin loading)|go:"GO:0099115"(chromosome, subtelomeric region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|refseq:XP_001713063.1|dip:DIP-37866N|reactome:R-SPO-2500257|reactome:R-SPO-2470946|reactome:R-SPO-3108214 refseq:NP_593449.1|dip:DIP-35736N|reactome:R-SPO-73772|reactome:R-SPO-983231|ensemblfungi:SPAC664.01c(gene)|ensemblfungi:SPAC664.01c.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006325"(chromatin organization)|go:"GO:0007533"(mating type switching)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0033696"(heterochromatin boundary formation)|go:"GO:0034507"(chromosome, centromeric outer repeat region)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044820"(mitotic telomere tethering at nuclear periphery)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1990342"(heterochromatin island)|go:"GO:1990758"(mitotic sister chromatid biorientation)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1E0B|rcsb pdb:2RSO - crc64:F45C2C2A2E0443CC crc64:F505CC8AC5E75EAB figure legend:Fig 4C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/10/25 2014/10/16 rogid:YGBl7BeNmXGxm6AgkpiyZ8T14Ow284812 rogid:EEISpq3oLJ9jyNp6870DB1Z3xCY284812 intact-crc:2AC932A5835FBB01|rigid:eAx8bRsqsiRyAelAmr1LooZzmV0 false green fluorescent protein tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O13816 uniprotkb:O59836 intact:EBI-1131314|uniprotkb:Q38G50|uniprotkb:Q9US16|ensemblfungi:"SPAC17H9.20.1:pep" intact:EBI-908382|ensemblfungi:"SPCC550.13.1:pep" psi-mi:scc3_schpo(display_long)|uniprotkb:SCC3 homolog(gene name synonym)|uniprotkb:psc3(gene name)|psi-mi:psc3(display_short)|uniprotkb:SPAC17H9.20(orf name)|uniprotkb:SPAC607.01(orf name) psi-mi:him1_schpo(display_long)|uniprotkb:SPCC550.13(orf name)|uniprotkb:him1(gene name)|psi-mi:him1(display_short)|uniprotkb:dfp1(gene name synonym)|uniprotkb:rad35(gene name synonym)|uniprotkb:DNA repair protein rad35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bailis et al. (2003) pubmed:14625560 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1131298 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPAC17H9.20(gene)|ensemblfungi:SPAC17H9.20.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0030892"(mitotic cohesin complex)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:0061780"(mitotic cohesin loading)|go:"GO:0099115"(chromosome, subtelomeric region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|refseq:XP_001713063.1|dip:DIP-37866N|reactome:R-SPO-2500257|reactome:R-SPO-2470946|reactome:R-SPO-3108214 refseq:NP_588105.1|interpro:IPR001357(BRCT)|interpro:IPR013939(Regulatory subunit Dfp1/Him1, central region)|interpro:IPR006572(Zinc finger, DBF-type)|interpro:IPR038545|interpro:IPR036420|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPCC550.13(gene)|ensemblfungi:SPCC550.13.1(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0048478"(replication fork protection)|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1903466"(regulation of mitotic DNA replication initiation)|go:"GO:1903468"(positive regulation of DNA replication initiation) - crc64:F45C2C2A2E0443CC - figure legend:Fig 4C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/10/25 2014/10/16 rogid:YGBl7BeNmXGxm6AgkpiyZ8T14Ow284812 rogid:jqgB/+ji7/8agWCnJgorOov7kmA284812 intact-crc:2AC932A5835FBB01|rigid:eAx8bRsqsiRyAelAmr1LooZzmV0 false green fluorescent protein tag:c-c myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)