#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P08877 uniprotkb:Q9RE09 intact:EBI-1034482|ensemblbacteria:CAB13263 intact:EBI-1034475 psi-mi:pthp_bacsu(display_long)|uniprotkb:ptsH(gene name)|psi-mi:ptsH(display_short)|uniprotkb:BSU13900(locus name)|uniprotkb:Histidine-containing protein(gene name synonym) psi-mi:hprk_lacca(display_long)|uniprotkb:hprK(gene name)|psi-mi:hprK(display_short)|uniprotkb:"HPr(Ser) kinase/phosphorylase"(gene name synonym)|uniprotkb:HPr kinase/phosphatase(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fieulaine et al. (2002) pubmed:12359875 taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) taxid:1582(lacca)|taxid:1582(Lactobacillus casei) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1034497|rcsb pdb:1KKM - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_389273.1|interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR002114(Phosphotransferase system, HPr serine phosphorylation site)|rcsb pdb:1JEM|rcsb pdb:1KKL|rcsb pdb:1KKM|rcsb pdb:1SPH|rcsb pdb:2FEP|rcsb pdb:2HID|rcsb pdb:2HPR|rcsb pdb:3OQM|rcsb pdb:3OQN|rcsb pdb:3OQO|ensemblbacteria:BSU_13900(gene)|ensemblbacteria:CAB13263(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0043610"(regulation of carbohydrate utilization)|refseq:WP_003154654.1|interpro:IPR035895 interpro:IPR003755("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase")|interpro:IPR011104("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, C-terminal")|interpro:IPR011126("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, N-terminal")|rcsb pdb:1JB1|rcsb pdb:1KKL|rcsb pdb:1KKM|rcsb pdb:2QMH|interpro:IPR027417|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|refseq:WP_003564222.1|interpro:IPR028979 - - - assembly:dodecameric, multimeric|3d-r-factors:working 80.0%, free 74.300%|3d-resolution:2.8A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:QTzy5bnUrfVh/Phzx3dE6g9khjY224308 rogid:uPqUgmkeuOsE9G7g4wnjkarRdaw1582 intact-crc:E72033FA0EC6E035|rigid:K5OJ4mPyl+BDurmdVDKj0EcsR1M false sufficient binding region:2-88 sufficient binding region:128-319 3 3 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)