#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32485 uniprotkb:Q02100 intact:EBI-8437|uniprotkb:Q06232|uniprotkb:Q12294|uniprotkb:D6VYB1|ensemblfungi:YLR113W intact:EBI-17289|uniprotkb:D6W115|ensemblfungi:YNL167C psi-mi:hog1_yeast(display_long)|uniprotkb:HOG1(gene name)|psi-mi:HOG1(display_short)|uniprotkb:SSK3(gene name synonym)|uniprotkb:YLR113W(locus name)|uniprotkb:L2931(orf name)|uniprotkb:L9354.2(orf name)|uniprotkb:High osmolarity glycerol response protein 1(gene name synonym) psi-mi:sko1_yeast(display_long)|uniprotkb:SKO1(gene name)|psi-mi:SKO1(display_short)|uniprotkb:ACR1(gene name synonym)|uniprotkb:YNL167C(locus name)|uniprotkb:N1702(orf name) psi-mi:"MI:0096"(pull down) Proft et al. (2002) pubmed:12086627|imex:IM-19683 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1167652|imex:IM-19683-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013214.1|sgd:S000004103|dip:DIP-1558N|mint:P32485|ensemblfungi:YLR113W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038783|reactome:R-SCE-168638|reactome:R-SCE-193648|reactome:R-SCE-198753|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-418592|reactome:R-SCE-432142|reactome:R-SCE-450321|reactome:R-SCE-450341|reactome:R-SCE-525793|reactome:R-SCE-6798695|reactome:R-SCE-9007892|ensemblfungi:YLR113W(gene) refseq:NP_014232.1|sgd:S000005111|ensemblfungi:YNL167C(gene)|ensemblfungi:YNL167C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051019"(mitogen-activated protein kinase binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR020956|reactome:R-SCE-3214847|reactome:R-SCE-450341|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|dip:DIP-700N|mint:Q02100 - crc64:D95A20242587CE06 - figure legend:2B and C|comment:Mutation of the SKO1 phosphorylation sites Ser-108, Thr-113 and Ser-123 to alanine did not change the interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/11/17 2014/10/16 rogid:Re8xLAJEvP2Fjr0lOGtLB6ANybM559292 rogid:IcQvyxqkshScg9aNFCq22YzqL90559292 intact-crc:29F9B35309D21E94|rigid:uhGTiZe9jpRMw0jLVMrHp87Z5U0 false ha tag:n-n glutathione s tranferase tag:?-?|binding-associated region:1-315 - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot)