#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P11077 uniprotkb:P11077 intact:EBI-1032832|uniprotkb:Q85657|uniprotkb:Q8QR20 intact:EBI-1032832|uniprotkb:Q85657|uniprotkb:Q8QR20 psi-mi:mu1_reovl(display_long)|uniprotkb:M2(gene name)|psi-mi:M2(display_short) psi-mi:mu1_reovl(display_long)|uniprotkb:M2(gene name)|psi-mi:M2(display_short) psi-mi:"MI:0114"(x-ray crystallography) Liemann et al. (2002) pubmed:11832217 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1032844|rcsb pdb:1JMU - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009113(Mu1 membrane penetration protein)|interpro:IPR015962(Mu1 membrane penetration protein, alpha-bundle subdomain 2)|interpro:IPR015961(Mu1 membrane penetration protein, alpha/beta subdomain)|interpro:IPR015960(Mu1 membrane penetration protein, beta-sandwich subdomain)|rcsb pdb:1JMU|rcsb pdb:2CSE|go:"GO:0016020"(membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039624"(viral outer capsid)|go:"GO:0039665"(permeabilization of host organelle membrane involved in viral entry into host cell)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0046812"(host cell surface binding)|go:"GO:0099008"(viral entry via permeabilization of inner membrane)|interpro:IPR036256|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ interpro:IPR009113(Mu1 membrane penetration protein)|interpro:IPR015962(Mu1 membrane penetration protein, alpha-bundle subdomain 2)|interpro:IPR015961(Mu1 membrane penetration protein, alpha/beta subdomain)|interpro:IPR015960(Mu1 membrane penetration protein, beta-sandwich subdomain)|rcsb pdb:1JMU|rcsb pdb:2CSE|go:"GO:0016020"(membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039624"(viral outer capsid)|go:"GO:0039665"(permeabilization of host organelle membrane involved in viral entry into host cell)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0046812"(host cell surface binding)|go:"GO:0099008"(viral entry via permeabilization of inner membrane)|interpro:IPR036256|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ - - - assembly:nonameric, multimeric|3d-r-factors:working 78.400%, free 75.900%|3d-resolution:2.8A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:gs/9zCEDaCH3MV8BbRC4wSN9vOY10884 rogid:gs/9zCEDaCH3MV8BbRC4wSN9vOY10884 intact-crc:77874AA3161534B6|rigid:hBF1YwyvZcFoJiAn71D238015HM false sufficient binding region:2-42 sufficient binding region:43-708 3 3 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11077 uniprotkb:Q86292 intact:EBI-1032832|uniprotkb:Q85657|uniprotkb:Q8QR20 intact:EBI-1032824 psi-mi:mu1_reovl(display_long)|uniprotkb:M2(gene name)|psi-mi:M2(display_short) psi-mi:q86292_9reov(display_long)|uniprotkb:S4(gene name)|psi-mi:S4(display_short) psi-mi:"MI:0114"(x-ray crystallography) Liemann et al. (2002) pubmed:11832217 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:10891(reosp)|taxid:10891(Reovirus sp.) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1032844|rcsb pdb:1JMU - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009113(Mu1 membrane penetration protein)|interpro:IPR015962(Mu1 membrane penetration protein, alpha-bundle subdomain 2)|interpro:IPR015961(Mu1 membrane penetration protein, alpha/beta subdomain)|interpro:IPR015960(Mu1 membrane penetration protein, beta-sandwich subdomain)|rcsb pdb:1JMU|rcsb pdb:2CSE|go:"GO:0016020"(membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039624"(viral outer capsid)|go:"GO:0039665"(permeabilization of host organelle membrane involved in viral entry into host cell)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0046812"(host cell surface binding)|go:"GO:0099008"(viral entry via permeabilization of inner membrane)|interpro:IPR036256|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ interpro:IPR000153(Outer capsid sigma 3, reoviral)|interpro:IPR023634|go:"GO:0005198"(structural molecule activity)|go:"GO:0019058"(viral life cycle) - - - assembly:nonameric, multimeric|3d-r-factors:working 78.400%, free 75.900%|3d-resolution:2.8A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:gs/9zCEDaCH3MV8BbRC4wSN9vOY10884 rogid:CfPNd6rFZ0gmkAuCp2+Tt81RDR410891 intact-crc:77874AA3161534B6|rigid:hBF1YwyvZcFoJiAn71D238015HM false sufficient binding region:2-42 sufficient binding region:1-365 3 3 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)