#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q15599 uniprotkb:Q01814-1 intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005|intact:EBI-15579694 intact:EBI-1174262|ensembl:ENSP00000353414|ensembl:ENSP00000494716 psi-mi:nhrf2_human(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:q01814-1(display_long)|uniprotkb:AIIICI(isoform synonym)|uniprotkb:ATP2B2(gene name)|psi-mi:ATP2B2(display_short)|uniprotkb:PMCA2(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 2(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeMarco et al. (2002) pubmed:11786550|imex:IM-19693 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1174721|imex:IM-19693-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|ensembl:ENSG00000065054(gene)|ensembl:ENST00000424542(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031197|interpro:IPR036034|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|go:"GO:0042802"(identical protein binding)|dip:DIP-29093N intact:EBI-1174243(at2b2_human)|ensembl:ENSG00000157087(gene)|ensembl:ENST00000360273(transcript)|ensembl:ENST00000645850(transcript) - - - figure legend:1|comment:Isoform accession number found by research through authors' previous papers|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/12/04 2014/10/16 rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606 rogid:bCD7j13UJUgWoSHShHLKJBiVGJM9606 intact-crc:7974F37D9331DBE8|rigid:Y1zleQFXryQjIuq+4r4G8jvkzx8 false sufficient binding region:140-337 sufficient binding region:1172-1243 - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q8SQG9 uniprotkb:Q01814-1 intact:EBI-1174758 intact:EBI-1174262|ensembl:ENSP00000353414|ensembl:ENSP00000494716 psi-mi:nhrf2_rabit(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:PDZ domain-containing protein NHERF-2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:q01814-1(display_long)|uniprotkb:AIIICI(isoform synonym)|uniprotkb:ATP2B2(gene name)|psi-mi:ATP2B2(display_short)|uniprotkb:PMCA2(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 2(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 2(gene name synonym) psi-mi:"MI:0096"(pull down) DeMarco et al. (2002) pubmed:11786550|imex:IM-19693 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1174740|imex:IM-19693-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:NP_001075576.1|interpro:IPR031197|go:"GO:0005634"(nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR036034 intact:EBI-1174243(at2b2_human)|ensembl:ENSG00000157087(gene)|ensembl:ENST00000360273(transcript)|ensembl:ENST00000645850(transcript) - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2006/12/04 2014/10/16 rogid:6tAxAfhRA5wjSikCvOHoM5Qm1Ik9986 rogid:bCD7j13UJUgWoSHShHLKJBiVGJM9606 intact-crc:CB63E169F1C5EE7C|rigid:TucnXw4QjUTyLw6bFXSiaYNgpM0 false ha tag:n-n sufficient binding region:1172-1243|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01814-1 uniprotkb:Q8SQG9 intact:EBI-1174262|ensembl:ENSP00000353414|ensembl:ENSP00000494716 intact:EBI-1174758 psi-mi:q01814-1(display_long)|uniprotkb:AIIICI(isoform synonym)|uniprotkb:ATP2B2(gene name)|psi-mi:ATP2B2(display_short)|uniprotkb:PMCA2(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 2(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 2(gene name synonym) psi-mi:nhrf2_rabit(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:PDZ domain-containing protein NHERF-2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) DeMarco et al. (2002) pubmed:11786550|imex:IM-19693 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1174778|imex:IM-19693-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1174243(at2b2_human)|ensembl:ENSG00000157087(gene)|ensembl:ENST00000360273(transcript)|ensembl:ENST00000645850(transcript) interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:NP_001075576.1|interpro:IPR031197|go:"GO:0005634"(nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR036034 - - - figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2006/12/04 2014/10/16 rogid:bCD7j13UJUgWoSHShHLKJBiVGJM9606 rogid:6tAxAfhRA5wjSikCvOHoM5Qm1Ik9986 intact-crc:449CE3C394DBD5CA|rigid:TucnXw4QjUTyLw6bFXSiaYNgpM0 false - ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01814-1 uniprotkb:Q8SQG9 intact:EBI-1174262|ensembl:ENSP00000353414|ensembl:ENSP00000494716 intact:EBI-1174758 psi-mi:q01814-1(display_long)|uniprotkb:AIIICI(isoform synonym)|uniprotkb:ATP2B2(gene name)|psi-mi:ATP2B2(display_short)|uniprotkb:PMCA2(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 2(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 2(gene name synonym) psi-mi:nhrf2_rabit(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:PDZ domain-containing protein NHERF-2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) DeMarco et al. (2002) pubmed:11786550|imex:IM-19693 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1174974|imex:IM-19693-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1174243(at2b2_human)|ensembl:ENSG00000157087(gene)|ensembl:ENST00000360273(transcript)|ensembl:ENST00000645850(transcript) interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:NP_001075576.1|interpro:IPR031197|go:"GO:0005634"(nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR036034 go:"GO:0005886"(plasma membrane) - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2006/12/04 2014/10/16 rogid:bCD7j13UJUgWoSHShHLKJBiVGJM9606 rogid:6tAxAfhRA5wjSikCvOHoM5Qm1Ik9986 intact-crc:17265AA9423DDB5F|rigid:TucnXw4QjUTyLw6bFXSiaYNgpM0 false sufficient binding region:4-1212|green fluorescent protein tag:?-? ha tag:n-n - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)