#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P47017 uniprotkb:P39517 intact:EBI-174|ensemblfungi:YJL124C|uniprotkb:D6VW62 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C psi-mi:lsm1_yeast(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:SPB8(gene name synonym)|uniprotkb:YJL124C(locus name)|uniprotkb:J0714(orf name)|uniprotkb:SPB8 protein(gene name synonym) psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:"MI:0096"(pull down) Coller et al. (2001) pubmed:11780629|imex:IM-18887 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-969808|imex:IM-18887-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012411.1|sgd:S000003660|rcsb pdb:4M75|reactome:R-SCE-430039|ensemblfungi:YJL124C(gene)|ensemblfungi:YJL124C_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|rcsb pdb:4C8Q|rcsb pdb:4C92|mint:P47017|dip:DIP-1330N sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 go:"GO:0000932"(P-body) crc64:2632FA5288E178A2 crc64:062CFA56DF6F2CEE figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/07/12 2014/10/16 rogid:7WmwhwOOHPT7qJ7sexTqdb43md8559292 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 intact-crc:51C10D14CAD52FC5|rigid:m3qcDyFjwh0Rh/kQUDdFxhPdPsE false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P39517 uniprotkb:P25644 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-204|uniprotkb:Q8NKJ3|uniprotkb:D6VR80|ensemblfungi:YCR077C psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:pat1_yeast(display_long)|uniprotkb:PAT1(gene name)|psi-mi:PAT1(display_short)|uniprotkb:Decapping activator and translational repressor PAT1(gene name synonym)|uniprotkb:mRNA turnover protein 1(gene name synonym)|uniprotkb:MRT1(gene name synonym)|uniprotkb:Topoisomerase II-associated protein PAT1(gene name synonym)|uniprotkb:YCR77C(orf name)|uniprotkb:YCR077C(locus name) psi-mi:"MI:0096"(pull down) Coller et al. (2001) pubmed:11780629|imex:IM-18887 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-969816|imex:IM-18887-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 refseq:NP_010002.3|sgd:S000000673|mint:P25644|dip:DIP-883N|ensemblfungi:YCR077C(gene)|ensemblfungi:YCR077C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000776"(kinetochore)|go:"GO:0000932"(P-body)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033962"(P-body assembly)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051301"(cell division)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR019167|interpro:IPR039900|rcsb pdb:4BRW|rcsb pdb:4C8Q|rcsb pdb:4N0A|rcsb pdb:4OGP|rcsb pdb:4OJJ|rcsb pdb:5LM5|rcsb pdb:5LMF|rcsb pdb:5LMG|reactome:R-SCE-430039 go:"GO:0000932"(P-body) crc64:062CFA56DF6F2CEE crc64:2DBE1210C173E468 figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/07/12 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:kov8R0RAgIOPffQ7ydjCUxjoE/M559292 intact-crc:AE7F0A43D8FDF452|rigid:cdAkbB9vnOm/eID5jNKGA5ijV8k false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P39517 uniprotkb:P39008 intact:EBI-158|uniprotkb:D6VRJ0|ensemblfungi:YDL160C intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:dhh1_yeast(display_long)|uniprotkb:DHH1(gene name)|psi-mi:DHH1(display_short)|uniprotkb:DExD/H-box helicase 1(gene name synonym)|uniprotkb:YDL160C(locus name) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Coller et al. (2001) pubmed:11780629|imex:IM-18887 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-969823|imex:IM-18887-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002319|refseq:NP_010121.1|mint:P39517|dip:DIP-1243N|ensemblfungi:YDL160C(gene)|ensemblfungi:YDL160C_mRNA(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045900"(negative regulation of translational elongation)|go:"GO:0051028"(mRNA transport)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:1S2M|rcsb pdb:4BRU|rcsb pdb:4BRW|reactome:R-SCE-430039 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N go:"GO:0000932"(P-body) crc64:062CFA56DF6F2CEE crc64:F3CAF97106A65933 figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/07/12 2014/10/16 rogid:XpeDqez6GN2a1QNzrKnQ8tnd8gw559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:3BC8282F821EA1A4|rigid:K/XKJn19DUHBCASdo3DjK3xLA3U false flag tag:n-n myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P39008 uniprotkb:Q12517 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-38519|uniprotkb:D6W1S0|ensemblfungi:YOL149W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:dcp1_yeast(display_long)|uniprotkb:DCP1(gene name)|psi-mi:DCP1(display_short)|uniprotkb:YOL149W(locus name) psi-mi:"MI:0096"(pull down) Coller et al. (2001) pubmed:11780629|imex:IM-18887 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-969832|imex:IM-18887-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N refseq:NP_014492.1|sgd:S000005509|mint:Q12517|dip:DIP-1288N|ensemblfungi:YOL149W(gene)|ensemblfungi:YOL149W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:0098745"(Dcp1-Dcp2 complex)|interpro:IPR010334(Dcp1-like decapping)|rcsb pdb:1Q67|rcsb pdb:6Y3Z|reactome:R-SCE-430039|reactome:R-SCE-450385|reactome:R-SCE-450513 go:"GO:0000932"(P-body) crc64:F3CAF97106A65933 crc64:8456B1C96C121C4D figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/07/12 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:CXLHokbNWY54t80lw79Or4Wmb1g559292 intact-crc:BFC9BE2F236DED15|rigid:xaX0KR08l9ezCG6J9YyPklJSLCs false myc tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)