#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00974 uniprotkb:Q9Y5Y6 intact:EBI-1032263 intact:EBI-1032242|uniprotkb:Q9BS01|uniprotkb:Q9H3S0|uniprotkb:Q9HB36|uniprotkb:Q9HCA3|ensembl:ENSP00000278742 psi-mi:bpt1_bovin(display_long)|uniprotkb:Basic protease inhibitor(gene name synonym)|uniprotkb:Aprotinin(gene name synonym) psi-mi:st14_human(display_long)|uniprotkb:ST14(gene name)|psi-mi:ST14(display_short)|uniprotkb:PRSS14(gene name synonym)|uniprotkb:SNC19(gene name synonym)|uniprotkb:TADG15(gene name synonym)|uniprotkb:Serine protease 14(gene name synonym)|uniprotkb:Matriptase(gene name synonym)|uniprotkb:Membrane-type serine protease 1(gene name synonym)|uniprotkb:Prostamin(gene name synonym)|uniprotkb:Serine protease TADG-15(gene name synonym)|uniprotkb:Tumor-associated differentially-expressed gene 15 protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Friedrich et al. (2002) pubmed:11696548 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1032273|rcsb pdb:1EAW - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0032023"(trypsinogen activation)|go:"GO:0035375"(zymogen binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0097180"(serine protease inhibitor complex)|go:"GO:1900004"(negative regulation of serine-type endopeptidase activity)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR020901|interpro:IPR036880|rcsb pdb:1D0D|rcsb pdb:1EAW|rcsb pdb:1EJM|rcsb pdb:1F5R|rcsb pdb:1AAL|rcsb pdb:1F7Z|rcsb pdb:1FAK|rcsb pdb:1FAN|rcsb pdb:1FY8|rcsb pdb:1G6X|rcsb pdb:1JV8|rcsb pdb:1JV9|rcsb pdb:1K09|rcsb pdb:1B0C|rcsb pdb:1K6U|rcsb pdb:1LD5|rcsb pdb:1BHC|rcsb pdb:1BPI|rcsb pdb:1LD6|rcsb pdb:1MTN|rcsb pdb:1BPT|rcsb pdb:1BRB|rcsb pdb:1NAG|rcsb pdb:1BTH|rcsb pdb:1BTI|rcsb pdb:1OA5|rcsb pdb:1OA6|rcsb pdb:1P2I|rcsb pdb:1P2J|rcsb pdb:1P2K|rcsb pdb:1P2M|rcsb pdb:1P2N|rcsb pdb:1P2O|rcsb pdb:1P2Q|rcsb pdb:1PIT|rcsb pdb:1BZ5|rcsb pdb:1QLQ|rcsb pdb:1T7C|rcsb pdb:1T8L|rcsb pdb:1T8M|rcsb pdb:1T8N|rcsb pdb:1T8O|rcsb pdb:1TPA|rcsb pdb:1BZX|rcsb pdb:1UUA|rcsb pdb:1UUB|rcsb pdb:1YKT|rcsb pdb:1YLC|rcsb pdb:1CBW|rcsb pdb:1YLD|rcsb pdb:2FI3|rcsb pdb:2FI4|rcsb pdb:2FI5|rcsb pdb:2FTL|rcsb pdb:1CO7|rcsb pdb:2FTM|rcsb pdb:2HEX|rcsb pdb:2IJO|rcsb pdb:2KAI|rcsb pdb:2PTC|rcsb pdb:2R9P|rcsb pdb:2RA3|rcsb pdb:2TGP|rcsb pdb:2TPI|rcsb pdb:2ZJX|rcsb pdb:2ZVX|rcsb pdb:3BTD|rcsb pdb:3BTE|rcsb pdb:3BTF|rcsb pdb:3BTG|rcsb pdb:3BTH|rcsb pdb:3BTK|rcsb pdb:3BTM|rcsb pdb:3BTQ|rcsb pdb:3BTT|rcsb pdb:3BTW|rcsb pdb:3FP6|rcsb pdb:3FP7|rcsb pdb:3FP8|rcsb pdb:3GYM|rcsb pdb:3LDI|rcsb pdb:3LDJ|rcsb pdb:3LDM|rcsb pdb:3OTJ|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:3TGI|rcsb pdb:3TGJ|rcsb pdb:3TGK|rcsb pdb:3TPI|rcsb pdb:3U1J|rcsb pdb:3WNY|rcsb pdb:4BNR|rcsb pdb:4DG4|rcsb pdb:4PTI|rcsb pdb:4TPI|rcsb pdb:4WWY|rcsb pdb:4WXV|rcsb pdb:4Y0Y|rcsb pdb:4Y0Z|rcsb pdb:4Y10|rcsb pdb:4Y11|rcsb pdb:5JB4|rcsb pdb:5JB5|rcsb pdb:5JB6|rcsb pdb:5JB7|rcsb pdb:5PTI|rcsb pdb:5XX2|rcsb pdb:5XX3|rcsb pdb:5XX4|rcsb pdb:5XX5|rcsb pdb:5XX6|rcsb pdb:5XX7|rcsb pdb:5XX8|rcsb pdb:5YVU|rcsb pdb:5YW1|rcsb pdb:6F1F|rcsb pdb:6PTI|rcsb pdb:7PTI|rcsb pdb:8PTI|rcsb pdb:9PTI|mint:P00974|dip:DIP-6113N refseq:NP_068813.1|ensembl:ENSG00000149418(gene)|ensembl:ENST00000278742(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0060672"(epithelial cell morphogenesis involved in placental branching)|interpro:IPR000082(SEA)|interpro:IPR000859(CUB)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR017051(Suppressor of tumourigenicity 14)|interpro:IPR018114|interpro:IPR023415|interpro:IPR033116|interpro:IPR035914|interpro:IPR036055|interpro:IPR036364|interpro:IPR043504|rcsb pdb:1EAW|rcsb pdb:1EAX|rcsb pdb:2FMV|rcsb pdb:2GV6|rcsb pdb:2GV7|rcsb pdb:3BN9|rcsb pdb:3NCL|rcsb pdb:3NPS|rcsb pdb:3P8F|rcsb pdb:3P8G|rcsb pdb:3SO3|rcsb pdb:4IS5|rcsb pdb:4ISL|rcsb pdb:4ISN|rcsb pdb:4ISO|rcsb pdb:4JYT|rcsb pdb:4JZ1|rcsb pdb:4JZI|rcsb pdb:4O97|rcsb pdb:4O9V|rcsb pdb:4R0I|rcsb pdb:5LYO|rcsb pdb:6N4T|rcsb pdb:6T9T|reactome:R-HSA-6809371 - - - assembly:tetrameric, multimeric|3d-r-factors:working 80.100%, free 72.100%|3d-resolution:2.93A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:yNcGpj9WW2ZQ83vl7hiQqhKZLdQ9913 rogid:IwO4f5VliRMViLSrNhx6MsxFcAc9606 intact-crc:5670FD901C54AB17|rigid:vwqtidhSiBsNS4F89CLWhCldGzg false sufficient binding region:36-93 sufficient binding region:615-855 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)