#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q61526 uniprotkb:Q9UQ80 intact:EBI-931878|uniprotkb:Q3KQR1|uniprotkb:Q68J64|uniprotkb:Q810U8|uniprotkb:Q8K317|ensembl:ENSMUSP00000080716 intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886 psi-mi:erbb3_mouse(display_long)|uniprotkb:Erbb3(gene name)|psi-mi:Erbb3(display_short)|uniprotkb:Glial growth factor receptor(gene name synonym)|uniprotkb:Proto-oncogene-like protein c-ErbB-3(gene name synonym) psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lessor et al. (2001) pubmed:11325528|imex:IM-19621 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-931900|imex:IM-19621-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034283.1|ensembl:ENSMUSG00000018166(gene)|ensembl:ENSMUST00000082059(transcript)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0021545"(cranial nerve development)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038131"(neuregulin receptor activity)|go:"GO:0038132"(neuregulin binding)|go:"GO:0038143"("ERBB3:ERBB2 complex")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051048"(negative regulation of secretion)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0055025"(positive regulation of cardiac muscle tissue development)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|reactome:R-MMU-1358803 refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349 - - - antagonist:"Inhibition of PKC (by incubation with BIS) abolished the interaction."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2006/04/28 2014/10/16 rogid:HFP4VR1PpgpvSVSKWkV5iDI8FF010090 rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606 intact-crc:2F0E06340A8B240B|rigid:skY5TO4Zm+2zmGZwSM9l8OG7UeY false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)