#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03300-PRO_0000040090 intact:EBI-914168 intact:EBI-914162 - psi-mi:p03300-pro_0000040090(display_long) psi-mi:ggcagcugcaugcagcugcc(display_short)|psi-mi:EBI-914168(display_long) psi-mi:"MI:0049"(filter binding) Hobson et al. (2001) pubmed:11230138|imex:IM-18988 taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") taxid:-1(in vitro)|taxid:-1(In vitro) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-914164|imex:IM-18988-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0320"(ribonucleic acid) intact:EBI-3436647(chain-parent) - go:"GO:0003725"(double-stranded RNA binding) chain-seq-start:1749|chain-seq-end:2209 - kinetics:"ED50 (wild-type)=3x10exp-6M"|comment:RNA strands bind to form a blunt ended double strand, authors name 0.20 RNA|figure legend:2A, 2C|comment:Protein bound single stranded RNA's with approximately 10 fold lower affinity.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2020/03/02 rogid:YaiQrYsEEITajcljoRBPAGHSh2U12081 crc64:2D471B084A326E06 intact-crc:36E671E97BDA5BA8 false mutation decreasing interaction:342-342|mutation decreasing interaction:348-348|mutation decreasing interaction:455-455|mutation decreasing interaction:456-456 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03300-PRO_0000040090 intact:EBI-944574 intact:EBI-914162 - psi-mi:p03300-pro_0000040090(display_long) psi-mi:ccgucgacguacgucgacgg(display_short)|psi-mi:EBI-944574(display_long) psi-mi:"MI:0049"(filter binding) Hobson et al. (2001) pubmed:11230138|imex:IM-18988 taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") taxid:-1(in vitro)|taxid:-1(In vitro) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-914164|imex:IM-18988-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0320"(ribonucleic acid) intact:EBI-3436647(chain-parent) - go:"GO:0003725"(double-stranded RNA binding) chain-seq-start:1749|chain-seq-end:2209 - kinetics:"ED50 (wild-type)=3x10exp-6M"|comment:RNA strands bind to form a blunt ended double strand, authors name 0.20 RNA|figure legend:2A, 2C|comment:Protein bound single stranded RNA's with approximately 10 fold lower affinity.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2020/03/02 rogid:YaiQrYsEEITajcljoRBPAGHSh2U12081 crc64:9D99223E3031F2D1 intact-crc:36E671E97BDA5BA8 false mutation decreasing interaction:342-342|mutation decreasing interaction:348-348|mutation decreasing interaction:455-455|mutation decreasing interaction:456-456 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03300-PRO_0000040090 intact:EBI-914181 intact:EBI-914162 - psi-mi:p03300-pro_0000040090(display_long) psi-mi:ggcgcggcagcugcaugcag(display_short)|psi-mi:EBI-914181(display_long) psi-mi:"MI:0049"(filter binding) Hobson et al. (2001) pubmed:11230138|imex:IM-18988 taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") taxid:-1(in vitro)|taxid:-1(In vitro) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-914187|imex:IM-18988-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0320"(ribonucleic acid) intact:EBI-3436647(chain-parent) - go:"GO:0003725"(double-stranded RNA binding) chain-seq-start:1749|chain-seq-end:2209 - kinetics:"ED50 (wild-type)=6x10exp-6M"|comment:RNA strands bind to form a blunt ended double strand, authors name 5.20 RNA|figure legend:2A, 2D|comment:Protein bound single stranded RNA's with approximately 10 fold lower affinity.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2020/03/02 rogid:YaiQrYsEEITajcljoRBPAGHSh2U12081 crc64:09042C083EF05694 intact-crc:C405395D37F3E495 false mutation decreasing interaction:348-348|mutation decreasing interaction:454-454|mutation decreasing interaction:455-455|mutation decreasing interaction:341-341|sufficient binding region:63-460 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03300-PRO_0000040090 intact:EBI-944576 intact:EBI-914162 - psi-mi:p03300-pro_0000040090(display_long) psi-mi:ccgucgacguacgucgac-2(display_short)|psi-mi:EBI-944576(display_long) psi-mi:"MI:0049"(filter binding) Hobson et al. (2001) pubmed:11230138|imex:IM-18988 taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") taxid:-1(in vitro)|taxid:-1(In vitro) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-914187|imex:IM-18988-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0320"(ribonucleic acid) intact:EBI-3436647(chain-parent) - go:"GO:0003725"(double-stranded RNA binding) chain-seq-start:1749|chain-seq-end:2209 - kinetics:"ED50 (wild-type)=6x10exp-6M"|comment:RNA strands bind to form a blunt ended double strand, authors name 5.20 RNA|figure legend:2A, 2D|comment:Protein bound single stranded RNA's with approximately 10 fold lower affinity.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2020/03/02 rogid:YaiQrYsEEITajcljoRBPAGHSh2U12081 crc64:0A412192B0FD9922 intact-crc:C405395D37F3E495 false mutation decreasing interaction:348-348|mutation decreasing interaction:454-454|mutation decreasing interaction:455-455|mutation decreasing interaction:341-341|sufficient binding region:63-460 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-944576 intact:EBI-914181 - - psi-mi:ccgucgacguacgucgac-2(display_short)|psi-mi:EBI-944576(display_long) psi-mi:ggcgcggcagcugcaugcag(display_short)|psi-mi:EBI-914181(display_long) psi-mi:"MI:0700"(rna directed rna polymerase assay) Hobson et al. (2001) pubmed:11230138|imex:IM-18988 taxid:-1(in vitro)|taxid:-1(In vitro) taxid:-1(in vitro)|taxid:-1(In vitro) psi-mi:"MI:0701"(dna strand elongation) psi-mi:"MI:0469"(IntAct) intact:EBI-914242|imex:IM-18988-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0320"(ribonucleic acid) - - go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0008270"(zinc ion binding) - - figure legend:Figure 2F and Figure 3|comment:RNA strands bind to form a blunt ended double stranded RNA, authors name 5.20 RNA|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2020/03/03 crc64:0A412192B0FD9922 crc64:09042C083EF05694 intact-crc:DB45F898E8528583 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-944576 uniprotkb:P03300-PRO_0000040090 - intact:EBI-914162 psi-mi:ccgucgacguacgucgac-2(display_short)|psi-mi:EBI-944576(display_long) psi-mi:p03300-pro_0000040090(display_long) psi-mi:"MI:0700"(rna directed rna polymerase assay) Hobson et al. (2001) pubmed:11230138|imex:IM-18988 taxid:-1(in vitro)|taxid:-1(In vitro) taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") psi-mi:"MI:0701"(dna strand elongation) psi-mi:"MI:0469"(IntAct) intact:EBI-914242|imex:IM-18988-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0327"(peptide) - intact:EBI-3436647(chain-parent) go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0008270"(zinc ion binding) - chain-seq-start:1749|chain-seq-end:2209 figure legend:Figure 2F and Figure 3|comment:RNA strands bind to form a blunt ended double stranded RNA, authors name 5.20 RNA|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2020/03/03 crc64:0A412192B0FD9922 rogid:YaiQrYsEEITajcljoRBPAGHSh2U12081 intact-crc:DB45F898E8528583 false - necessary binding region:1-64|mutation disrupting interaction strength:446-446,455-455|mutation decreasing interaction strength:455-456|mutation decreasing interaction strength:441-441|mutation decreasing interaction strength:342-342|mutation decreasing interaction strength:349-349|mutation decreasing interaction strength:455-455|mutation decreasing interaction strength:456-456 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:29105" intact:EBI-944576 intact:EBI-968340 - psi-mi:"zinc(2+)"(display_short)|psi-mi:"CHEBI:29105"(display_long) psi-mi:ccgucgacguacgucgac-2(display_short)|psi-mi:EBI-944576(display_long) psi-mi:"MI:0700"(rna directed rna polymerase assay) Hobson et al. (2001) pubmed:11230138|imex:IM-18988 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-1(in vitro)|taxid:-1(In vitro) psi-mi:"MI:0701"(dna strand elongation) psi-mi:"MI:0469"(IntAct) intact:EBI-914242|imex:IM-18988-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0682"(cofactor) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0320"(ribonucleic acid) - - go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0008270"(zinc ion binding) - - figure legend:Figure 2F and Figure 3|comment:RNA strands bind to form a blunt ended double stranded RNA, authors name 5.20 RNA|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2020/03/03 - crc64:0A412192B0FD9922 intact-crc:DB45F898E8528583 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P03300-PRO_0000040090 uniprotkb:P03300-PRO_0000040090 intact:EBI-914162 intact:EBI-914162 psi-mi:p03300-pro_0000040090(display_long) psi-mi:p03300-pro_0000040090(display_long) psi-mi:"MI:0030"(cross-linking study) Hobson et al. (2001) pubmed:11230138|imex:IM-18988 taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-944619|imex:IM-18988-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0327"(peptide) intact:EBI-3436647(chain-parent) intact:EBI-3436647(chain-parent) go:"GO:0042803"(protein homodimerization activity) chain-seq-start:1749|chain-seq-end:2209 chain-seq-start:1749|chain-seq-end:2209 figure legend:6E|comment:Under reducing conditions, only protein monomers are observed.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2020/03/02 rogid:YaiQrYsEEITajcljoRBPAGHSh2U12081 rogid:YaiQrYsEEITajcljoRBPAGHSh2U12081 intact-crc:062BEB37B0995BDE|rigid:UtbEBgd7a9jxnXkWZ3UZs+cJfG0 false mutation increasing interaction:441-441 mutation increasing interaction:29-29 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)