#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P88946	uniprotkb:P45481	intact:EBI-936023	intact:EBI-296306|uniprotkb:E9QPH4	psi-mi:p88946_hhv8(display_long)	psi-mi:cbp_mouse(display_long)|uniprotkb:Crebbp(gene name)|psi-mi:Crebbp(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Seo et al. (2000)	pubmed:10733899|imex:IM-19244	taxid:435895(humhe-2)|taxid:435895(Human herpesvirus 8 type M)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-936033|imex:IM-19244-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001346(Interferon regulatory factor)|interpro:IPR019471|interpro:IPR017855(SMAD domain-like)|interpro:IPR008984(SMAD/FHA domain)|mint:P88946|interpro:IPR036388|interpro:IPR036390|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)	go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000940"(outer kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043426"(MRF binding)|rcsb pdb:1KBH|rcsb pdb:1KDX|rcsb pdb:1JJS|rcsb pdb:1L8C|rcsb pdb:1R8U|rcsb pdb:1SB0|rcsb pdb:1TOT|rcsb pdb:1U2N|rcsb pdb:2AGH|rcsb pdb:2C52|rcsb pdb:2KA4|rcsb pdb:2KA6|rcsb pdb:2KKJ|rcsb pdb:2L14|rcsb pdb:2LQH|rcsb pdb:2LQI|rcsb pdb:2LWW|rcsb pdb:4I9O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5U4K|rcsb pdb:5U7G|rcsb pdb:5W0I|rcsb pdb:6DMX|rcsb pdb:6DNQ|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-5621575|reactome:R-MMU-8866907|reactome:R-MMU-8939246|reactome:R-MMU-8941856|reactome:R-MMU-9018519|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-9707564|go:"GO:0046332"(SMAD binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|rcsb pdb:1F81|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:P45481|dip:DIP-5974N	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/05/11	2014/10/16	rogid:GR1vQ73Rww0U0PV79AOq+y5GMVs435895	rogid:sBMFm6ZE5MtCDEN3UiSiwTbvSqA10090	intact-crc:90FE15E071F9842E|rigid:bTzofrnBPNFYop7rMS7qMAuJ65g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P45481	uniprotkb:P88946	intact:EBI-296306|uniprotkb:E9QPH4	intact:EBI-936023	psi-mi:cbp_mouse(display_long)|uniprotkb:Crebbp(gene name)|psi-mi:Crebbp(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym)	psi-mi:p88946_hhv8(display_long)	psi-mi:"MI:0018"(two hybrid)	Seo et al. (2000)	pubmed:10733899|imex:IM-19244	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:435895(humhe-2)|taxid:435895(Human herpesvirus 8 type M)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-936080|imex:IM-19244-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000940"(outer kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043426"(MRF binding)|rcsb pdb:1KBH|rcsb pdb:1KDX|rcsb pdb:1JJS|rcsb pdb:1L8C|rcsb pdb:1R8U|rcsb pdb:1SB0|rcsb pdb:1TOT|rcsb pdb:1U2N|rcsb pdb:2AGH|rcsb pdb:2C52|rcsb pdb:2KA4|rcsb pdb:2KA6|rcsb pdb:2KKJ|rcsb pdb:2L14|rcsb pdb:2LQH|rcsb pdb:2LQI|rcsb pdb:2LWW|rcsb pdb:4I9O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5U4K|rcsb pdb:5U7G|rcsb pdb:5W0I|rcsb pdb:6DMX|rcsb pdb:6DNQ|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-5621575|reactome:R-MMU-8866907|reactome:R-MMU-8939246|reactome:R-MMU-8941856|reactome:R-MMU-9018519|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-9707564|go:"GO:0046332"(SMAD binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|rcsb pdb:1F81|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:P45481|dip:DIP-5974N	interpro:IPR001346(Interferon regulatory factor)|interpro:IPR019471|interpro:IPR017855(SMAD domain-like)|interpro:IPR008984(SMAD/FHA domain)|mint:P88946|interpro:IPR036388|interpro:IPR036390|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2006/05/11	2014/10/16	rogid:sBMFm6ZE5MtCDEN3UiSiwTbvSqA10090	rogid:GR1vQ73Rww0U0PV79AOq+y5GMVs435895	intact-crc:8308B2FBAE3D0FF2|rigid:bTzofrnBPNFYop7rMS7qMAuJ65g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P45481	uniprotkb:P88946	intact:EBI-296306|uniprotkb:E9QPH4	intact:EBI-936023	psi-mi:cbp_mouse(display_long)|uniprotkb:Crebbp(gene name)|psi-mi:Crebbp(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym)	psi-mi:p88946_hhv8(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Seo et al. (2000)	pubmed:10733899|imex:IM-19244	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:435895(humhe-2)|taxid:435895(Human herpesvirus 8 type M)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-936091|imex:IM-19244-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000940"(outer kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043426"(MRF binding)|rcsb pdb:1KBH|rcsb pdb:1KDX|rcsb pdb:1JJS|rcsb pdb:1L8C|rcsb pdb:1R8U|rcsb pdb:1SB0|rcsb pdb:1TOT|rcsb pdb:1U2N|rcsb pdb:2AGH|rcsb pdb:2C52|rcsb pdb:2KA4|rcsb pdb:2KA6|rcsb pdb:2KKJ|rcsb pdb:2L14|rcsb pdb:2LQH|rcsb pdb:2LQI|rcsb pdb:2LWW|rcsb pdb:4I9O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5U4K|rcsb pdb:5U7G|rcsb pdb:5W0I|rcsb pdb:6DMX|rcsb pdb:6DNQ|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-5621575|reactome:R-MMU-8866907|reactome:R-MMU-8939246|reactome:R-MMU-8941856|reactome:R-MMU-9018519|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-9707564|go:"GO:0046332"(SMAD binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|rcsb pdb:1F81|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:P45481|dip:DIP-5974N	interpro:IPR001346(Interferon regulatory factor)|interpro:IPR019471|interpro:IPR017855(SMAD domain-like)|interpro:IPR008984(SMAD/FHA domain)|mint:P88946|interpro:IPR036388|interpro:IPR036390|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/05/11	2014/10/16	rogid:sBMFm6ZE5MtCDEN3UiSiwTbvSqA10090	rogid:GR1vQ73Rww0U0PV79AOq+y5GMVs435895	intact-crc:AE3DC0BD073B9628|rigid:bTzofrnBPNFYop7rMS7qMAuJ65g	false	ha tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P45481	uniprotkb:P88946	intact:EBI-296306|uniprotkb:E9QPH4	intact:EBI-936023	psi-mi:cbp_mouse(display_long)|uniprotkb:Crebbp(gene name)|psi-mi:Crebbp(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym)	psi-mi:p88946_hhv8(display_long)	psi-mi:"MI:0096"(pull down)	Seo et al. (2000)	pubmed:10733899|imex:IM-19244	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:435895(humhe-2)|taxid:435895(Human herpesvirus 8 type M)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-936111|imex:IM-19244-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000940"(outer kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043426"(MRF binding)|rcsb pdb:1KBH|rcsb pdb:1KDX|rcsb pdb:1JJS|rcsb pdb:1L8C|rcsb pdb:1R8U|rcsb pdb:1SB0|rcsb pdb:1TOT|rcsb pdb:1U2N|rcsb pdb:2AGH|rcsb pdb:2C52|rcsb pdb:2KA4|rcsb pdb:2KA6|rcsb pdb:2KKJ|rcsb pdb:2L14|rcsb pdb:2LQH|rcsb pdb:2LQI|rcsb pdb:2LWW|rcsb pdb:4I9O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5U4K|rcsb pdb:5U7G|rcsb pdb:5W0I|rcsb pdb:6DMX|rcsb pdb:6DNQ|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-5621575|reactome:R-MMU-8866907|reactome:R-MMU-8939246|reactome:R-MMU-8941856|reactome:R-MMU-9018519|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-9707564|go:"GO:0046332"(SMAD binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|rcsb pdb:1F81|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:P45481|dip:DIP-5974N	interpro:IPR001346(Interferon regulatory factor)|interpro:IPR019471|interpro:IPR017855(SMAD domain-like)|interpro:IPR008984(SMAD/FHA domain)|mint:P88946|interpro:IPR036388|interpro:IPR036390|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/11	2014/10/16	rogid:sBMFm6ZE5MtCDEN3UiSiwTbvSqA10090	rogid:GR1vQ73Rww0U0PV79AOq+y5GMVs435895	intact-crc:A31034C36B404CEC|rigid:bTzofrnBPNFYop7rMS7qMAuJ65g	false	35s radiolabel:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P88946	uniprotkb:P45481	intact:EBI-936023	intact:EBI-296306|uniprotkb:E9QPH4	psi-mi:p88946_hhv8(display_long)	psi-mi:cbp_mouse(display_long)|uniprotkb:Crebbp(gene name)|psi-mi:Crebbp(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Seo et al. (2000)	pubmed:10733899|imex:IM-19244	taxid:435895(humhe-2)|taxid:435895(Human herpesvirus 8 type M)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-936137|imex:IM-19244-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001346(Interferon regulatory factor)|interpro:IPR019471|interpro:IPR017855(SMAD domain-like)|interpro:IPR008984(SMAD/FHA domain)|mint:P88946|interpro:IPR036388|interpro:IPR036390|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)	go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000940"(outer kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043426"(MRF binding)|rcsb pdb:1KBH|rcsb pdb:1KDX|rcsb pdb:1JJS|rcsb pdb:1L8C|rcsb pdb:1R8U|rcsb pdb:1SB0|rcsb pdb:1TOT|rcsb pdb:1U2N|rcsb pdb:2AGH|rcsb pdb:2C52|rcsb pdb:2KA4|rcsb pdb:2KA6|rcsb pdb:2KKJ|rcsb pdb:2L14|rcsb pdb:2LQH|rcsb pdb:2LQI|rcsb pdb:2LWW|rcsb pdb:4I9O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5U4K|rcsb pdb:5U7G|rcsb pdb:5W0I|rcsb pdb:6DMX|rcsb pdb:6DNQ|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-5621575|reactome:R-MMU-8866907|reactome:R-MMU-8939246|reactome:R-MMU-8941856|reactome:R-MMU-9018519|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-9707564|go:"GO:0046332"(SMAD binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|rcsb pdb:1F81|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:P45481|dip:DIP-5974N	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/11	2014/10/16	rogid:GR1vQ73Rww0U0PV79AOq+y5GMVs435895	rogid:sBMFm6ZE5MtCDEN3UiSiwTbvSqA10090	intact-crc:E542E1CB58122263|rigid:bTzofrnBPNFYop7rMS7qMAuJ65g	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?|sufficient binding region:390-790(IPR003101)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P88946	uniprotkb:P45481	intact:EBI-936023	intact:EBI-296306|uniprotkb:E9QPH4	psi-mi:p88946_hhv8(display_long)	psi-mi:cbp_mouse(display_long)|uniprotkb:Crebbp(gene name)|psi-mi:Crebbp(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Seo et al. (2000)	pubmed:10733899|imex:IM-19244	taxid:435895(humhe-2)|taxid:435895(Human herpesvirus 8 type M)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-936150|imex:IM-19244-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001346(Interferon regulatory factor)|interpro:IPR019471|interpro:IPR017855(SMAD domain-like)|interpro:IPR008984(SMAD/FHA domain)|mint:P88946|interpro:IPR036388|interpro:IPR036390|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)	go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000940"(outer kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043426"(MRF binding)|rcsb pdb:1KBH|rcsb pdb:1KDX|rcsb pdb:1JJS|rcsb pdb:1L8C|rcsb pdb:1R8U|rcsb pdb:1SB0|rcsb pdb:1TOT|rcsb pdb:1U2N|rcsb pdb:2AGH|rcsb pdb:2C52|rcsb pdb:2KA4|rcsb pdb:2KA6|rcsb pdb:2KKJ|rcsb pdb:2L14|rcsb pdb:2LQH|rcsb pdb:2LQI|rcsb pdb:2LWW|rcsb pdb:4I9O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5U4K|rcsb pdb:5U7G|rcsb pdb:5W0I|rcsb pdb:6DMX|rcsb pdb:6DNQ|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-5621575|reactome:R-MMU-8866907|reactome:R-MMU-8939246|reactome:R-MMU-8941856|reactome:R-MMU-9018519|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-9707564|go:"GO:0046332"(SMAD binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|rcsb pdb:1F81|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:P45481|dip:DIP-5974N	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/11	2014/10/16	rogid:GR1vQ73Rww0U0PV79AOq+y5GMVs435895	rogid:sBMFm6ZE5MtCDEN3UiSiwTbvSqA10090	intact-crc:CCD7933E4D513964|rigid:bTzofrnBPNFYop7rMS7qMAuJ65g	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?|sufficient binding region:1680-1890	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)