#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00410	uniprotkb:Q04935	intact:EBI-5024|uniprotkb:A0A0A7NYF9|ensemblfungi:Q0250	intact:EBI-36910|uniprotkb:D6VSL2|ensemblfungi:YDR231C	psi-mi:cox2_yeast(display_long)|uniprotkb:COX2(gene name)|psi-mi:COX2(display_short)|uniprotkb:OXI1(gene name synonym)|uniprotkb:Q0250(locus name)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)	psi-mi:cox20_yeast(display_long)|uniprotkb:COX20(gene name)|psi-mi:COX20(display_short)|uniprotkb:YD9934.15c(orf name)|uniprotkb:YDR231C(locus name)	psi-mi:"MI:0030"(cross-linking study)	Hell et al. (2000)	pubmed:10671482|imex:IM-20103	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-967574|imex:IM-20103-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009326.1|sgd:S000007281|dip:DIP-7592N|mint:P00410|ensemblfungi:Q0250(gene)|ensemblfungi:Q0250_mRNA(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|rcsb pdb:6YMY	refseq:NP_010517.1|sgd:S000002639|mint:Q04935|dip:DIP-5755N|ensemblfungi:YDR231C(gene)|ensemblfungi:YDR231C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1902884"(positive regulation of response to oxidative stress)|interpro:IPR022533	go:"GO:0008535"(respiratory chain complex IV assembly)|go:"GO:0016485"(protein processing)|go:"GO:0009060"(aerobic respiration)	-	-	comment:No interaction was detected in mitochondria from strains deleted of OAX1, suggesting that the interaction occurs following OXA1-dependent export across the inner membrane|figure legend:7A, 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/11	2014/10/16	rogid:8vmkrxr7lNbwP25gqqNijmNPY4E559292	rogid:VJUlj5H4Fq9YlWXPBMWFKfSAuqw559292	intact-crc:86243A008E2FE285|rigid:cfL0q0f44zWgVzT+nMlA9FfVGhc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04935	uniprotkb:P00410	intact:EBI-36910|uniprotkb:D6VSL2|ensemblfungi:YDR231C	intact:EBI-5024|uniprotkb:A0A0A7NYF9|ensemblfungi:Q0250	psi-mi:cox20_yeast(display_long)|uniprotkb:COX20(gene name)|psi-mi:COX20(display_short)|uniprotkb:YD9934.15c(orf name)|uniprotkb:YDR231C(locus name)	psi-mi:cox2_yeast(display_long)|uniprotkb:COX2(gene name)|psi-mi:COX2(display_short)|uniprotkb:OXI1(gene name synonym)|uniprotkb:Q0250(locus name)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Hell et al. (2000)	pubmed:10671482|imex:IM-20103	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-993496|imex:IM-20103-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010517.1|sgd:S000002639|mint:Q04935|dip:DIP-5755N|ensemblfungi:YDR231C(gene)|ensemblfungi:YDR231C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1902884"(positive regulation of response to oxidative stress)|interpro:IPR022533	refseq:NP_009326.1|sgd:S000007281|dip:DIP-7592N|mint:P00410|ensemblfungi:Q0250(gene)|ensemblfungi:Q0250_mRNA(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|rcsb pdb:6YMY	go:"GO:0008535"(respiratory chain complex IV assembly)|go:"GO:0016485"(protein processing)|go:"GO:0009060"(aerobic respiration)	-	-	comment:No interaction was detected in mitochondria from strains deleted of OAX1, suggesting that the interaction occurs following OXA1-dependent export across the inner membrane|figure legend:7A, 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/11	2014/10/16	rogid:VJUlj5H4Fq9YlWXPBMWFKfSAuqw559292	rogid:8vmkrxr7lNbwP25gqqNijmNPY4E559292	intact-crc:A64EDE51B525205E|rigid:cfL0q0f44zWgVzT+nMlA9FfVGhc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04935	uniprotkb:P00410	intact:EBI-36910|uniprotkb:D6VSL2|ensemblfungi:YDR231C	intact:EBI-5024|uniprotkb:A0A0A7NYF9|ensemblfungi:Q0250	psi-mi:cox20_yeast(display_long)|uniprotkb:COX20(gene name)|psi-mi:COX20(display_short)|uniprotkb:YD9934.15c(orf name)|uniprotkb:YDR231C(locus name)	psi-mi:cox2_yeast(display_long)|uniprotkb:COX2(gene name)|psi-mi:COX2(display_short)|uniprotkb:OXI1(gene name synonym)|uniprotkb:Q0250(locus name)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hell et al. (2000)	pubmed:10671482|imex:IM-20103	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-967674|imex:IM-20103-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010517.1|sgd:S000002639|mint:Q04935|dip:DIP-5755N|ensemblfungi:YDR231C(gene)|ensemblfungi:YDR231C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1902884"(positive regulation of response to oxidative stress)|interpro:IPR022533	refseq:NP_009326.1|sgd:S000007281|dip:DIP-7592N|mint:P00410|ensemblfungi:Q0250(gene)|ensemblfungi:Q0250_mRNA(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|rcsb pdb:6GIQ|rcsb pdb:6HU9|rcsb pdb:6T0B|rcsb pdb:6T15|rcsb pdb:6YMX|rcsb pdb:6YMY	go:"GO:0008535"(respiratory chain complex IV assembly)|go:"GO:0016485"(protein processing)|go:"GO:0009060"(aerobic respiration)	-	-	figure legend:7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/11	2014/10/16	rogid:VJUlj5H4Fq9YlWXPBMWFKfSAuqw559292	rogid:8vmkrxr7lNbwP25gqqNijmNPY4E559292	intact-crc:8A12173E0CD289AB|rigid:cfL0q0f44zWgVzT+nMlA9FfVGhc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)