#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P12294	uniprotkb:P0CS90	intact:EBI-6490|uniprotkb:E9P9W9|uniprotkb:P05512	intact:EBI-8637|uniprotkb:D6VWL6|uniprotkb:P12398|ensemblfungi:YJR045C	psi-mi:ens2_yeasx(display_long)|uniprotkb:ENS2(gene name)|psi-mi:ENS2(display_short)|uniprotkb:RF3(gene name synonym)|uniprotkb:Endo.SceI 50 kDa subunit(gene name synonym)|uniprotkb:Maturase-like RF3 protein(gene name synonym)	psi-mi:hsp77_yeast(display_long)|uniprotkb:ENS1(gene name synonym)|uniprotkb:SSC1(gene name)|psi-mi:SSC1(display_short)|uniprotkb:YJR045C(locus name)|uniprotkb:J1639(orf name)|uniprotkb:mtHSP70(gene name synonym)|uniprotkb:Endonuclease SceI 75 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mizumura et al. (1999)	imex:IM-14465|pubmed:10464305	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-934109|imex:IM-14465-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000029698|dip:DIP-2N|go:"GO:0004519"(endonuclease activity)|go:"GO:0005739"(mitochondrion)|interpro:IPR004860(LAGLIDADG DNA endonuclease)|interpro:IPR027434	sgd:S000003806|refseq:NP_012579.1|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|mint:P0CS90|interpro:IPR043129|ensemblfungi:YJR045C(gene)|ensemblfungi:YJR045C_mRNA(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008566"(mitochondrial protein-transporting ATPase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043335"(protein unfolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)	psi-mi:"MI:0469"(intact)	-	caution:This sequence has been withdrawn from Uniprot.|crc64:1E5672E76FCE24AC	comment:SSC1 N-terminal ATP-ase domain was found to be sufficient for the interaction but the exact range was not specified.|comment:Has multi-site specific endonuclease activity.|figure legend:5|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/05	2014/10/16	rogid:g3iUd01EG5syK1NW2p26JGL/Te84932	rogid:jwa3ppE0voBqzfZAuY/E52tYrrw559292	intact-crc:EC92B216FC4C7CAF|rigid:cqgRjXzKm9BmUHSrF3G0Bxf7Ie0	false	his tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P12294	uniprotkb:P0CS90	intact:EBI-6490|uniprotkb:E9P9W9|uniprotkb:P05512	intact:EBI-8637|uniprotkb:D6VWL6|uniprotkb:P12398|ensemblfungi:YJR045C	psi-mi:ens2_yeasx(display_long)|uniprotkb:ENS2(gene name)|psi-mi:ENS2(display_short)|uniprotkb:RF3(gene name synonym)|uniprotkb:Endo.SceI 50 kDa subunit(gene name synonym)|uniprotkb:Maturase-like RF3 protein(gene name synonym)	psi-mi:hsp77_yeast(display_long)|uniprotkb:ENS1(gene name synonym)|uniprotkb:SSC1(gene name)|psi-mi:SSC1(display_short)|uniprotkb:YJR045C(locus name)|uniprotkb:J1639(orf name)|uniprotkb:mtHSP70(gene name synonym)|uniprotkb:Endonuclease SceI 75 kDa subunit(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Mizumura et al. (1999)	imex:IM-14465|pubmed:10464305	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-983180|imex:IM-14465-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000029698|dip:DIP-2N|go:"GO:0004519"(endonuclease activity)|go:"GO:0005739"(mitochondrion)|interpro:IPR004860(LAGLIDADG DNA endonuclease)|interpro:IPR027434	sgd:S000003806|refseq:NP_012579.1|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|mint:P0CS90|interpro:IPR043129|ensemblfungi:YJR045C(gene)|ensemblfungi:YJR045C_mRNA(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008566"(mitochondrial protein-transporting ATPase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043335"(protein unfolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)	psi-mi:"MI:0469"(intact)	-	caution:This sequence has been withdrawn from Uniprot.|crc64:1E5672E76FCE24AC	figure legend:2|comment:"The elution profile suggested a SSC1:ENS2 dimer. Only the fraction  containing the dimer showed endonuclease activity."|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/05	2014/10/16	rogid:g3iUd01EG5syK1NW2p26JGL/Te84932	rogid:jwa3ppE0voBqzfZAuY/E52tYrrw559292	intact-crc:402105687A684599|rigid:cqgRjXzKm9BmUHSrF3G0Bxf7Ie0	false	his tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)