#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12133 uniprotkb:P15367 intact:EBI-17829|uniprotkb:D6VY67|ensemblfungi:YLR066W intact:EBI-16513|uniprotkb:D6VVV3|ensemblfungi:YIR022W psi-mi:spc3_yeast(display_long)|uniprotkb:SPC3(gene name)|psi-mi:SPC3(display_short)|uniprotkb:YLR066W(locus name)|uniprotkb:L2186(orf name)|uniprotkb:Microsomal signal peptidase subunit 3(gene name synonym) psi-mi:sec11_yeast(display_long)|uniprotkb:SEC11(gene name)|psi-mi:SEC11(display_short)|uniprotkb:Signal peptidase I(gene name synonym)|uniprotkb:Secretory protein 11(gene name synonym)|uniprotkb:YIR022W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) VanValkenburgh et al. (1999) pubmed:10206957|imex:IM-18916 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-962438|imex:IM-18916-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004056|refseq:NP_013167.1|ensemblfungi:YLR066W(gene)|ensemblfungi:YLR066W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR007653(Signal peptidase 22 kDa subunit)|dip:DIP-5083N|mint:Q12133 refseq:NP_012288.1|sgd:S000001461|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR001733(Peptidase S26B, eukaryotic signal peptidase)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|interpro:IPR019756|interpro:IPR019758|interpro:IPR027245|interpro:IPR036286|ensemblfungi:YIR022W(gene)|ensemblfungi:YIR022W_mRNA(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-5667N|mint:P15367 - - - comment:SEC11 mutations ser44ala, his83phe and asp109glu had no effects on the interaction.|figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/07/05 2014/10/16 rogid:Yo9d2WsA1GUlNLc0oSPZhYk+fvs559292 rogid:t+RiGy79Pv7EbHywbjkd4BMyJwk559292 intact-crc:451CC1DFE547B83A|rigid:diUmB15IQXY6xdb7YVbp96hkmt0 false ha tag:?-? mutation decreasing interaction:103-103|flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)