#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P24472	uniprotkb:Q91Y86	intact:EBI-7842269|ensembl:ENSMUSP00000034903|uniprotkb:Q9CQ81|uniprotkb:Q9CY87|uniprotkb:Q9CTY7|intact:MINT-1487605|uniprotkb:Q9D038	intact:EBI-298784|ensembl:ENSMUSP00000107576	psi-mi:gsta4_mouse(display_long)|uniprotkb:Gsta4(gene name)|psi-mi:Gsta4(display_short)|uniprotkb:Gsta(gene name synonym)|uniprotkb:GST A4-4(gene name synonym)|uniprotkb:Glutathione S-transferase 5.7(gene name synonym)|uniprotkb:GST class-alpha member 4(gene name synonym)	psi-mi:mk08_mouse(display_long)|uniprotkb:Mapk8(gene name)|psi-mi:Mapk8(display_short)|uniprotkb:Jnk1(gene name synonym)|uniprotkb:Prkm8(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK1(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Desmots et al. (2005)	pubmed:16223495|imex:IM-10885|mint:MINT-5218005	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7842315|mint:MINT-68754|imex:IM-10885-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUST00000034903(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0009635"(response to herbicide)|go:"GO:0010043"(response to zinc ion)|go:"GO:0035094"(response to nicotine)|go:"GO:0071285"(cellular response to lithium ion)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P24472|rcsb pdb:1B48|rcsb pdb:1GUK|ensembl:ENSMUSG00000032348(gene)|refseq:NP_034487.2|mint:MINT-1487743(identity)	go:"GO:0009411"(response to UV)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034352"(positive regulation of glial cell apoptotic process)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:0048511"(rhythmic process)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0061833"(protein localization to tricellular tight junction)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090045"(positive regulation of deacetylase activity)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097441"(basal dendrite)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901485"(positive regulation of transcription factor catabolic process)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1904809"(regulation of dense core granule transport)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|mint:Q91Y86|reactome:R-MMU-139910|reactome:R-MMU-193648|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-376172|reactome:R-MMU-450321|reactome:R-MMU-450341|reactome:R-MMU-5693565|reactome:R-MMU-9007892|reactome:R-MMU-111446|ensembl:ENSMUSG00000021936(gene)|ensembl:ENSMUST00000111945(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001764"(neuron migration)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002102"(podosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0009408"(response to heat)|refseq:NP_057909.1|dip:DIP-31075N|mint:MINT-1487748(identity)	-	function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2005/11/01	2014/10/16	rogid:NOQwk+xfvdsLUtQjIujh63AclxA10090	rogid:PF6G6rHf26jidt+Mg3aFCvCm7pU10090	intact-crc:8DEF39BD827E725D|rigid:8jBVEVhVqiknLEEreuco7Q9i9QE	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P24472	uniprotkb:Q9WTU6	intact:EBI-7842269|ensembl:ENSMUSP00000034903|uniprotkb:Q9CQ81|uniprotkb:Q9CY87|uniprotkb:Q9CTY7|intact:MINT-1487605|uniprotkb:Q9D038	intact:EBI-298798|ensembl:ENSMUSP00000042744|ensembl:ENSMUSP00000136977|uniprotkb:Q8C097|uniprotkb:Q8VDD2|uniprotkb:Q9WTU4|uniprotkb:Q9WTU5|uniprotkb:Q5NCK9|uniprotkb:Q5NCL5	psi-mi:gsta4_mouse(display_long)|uniprotkb:Gsta4(gene name)|psi-mi:Gsta4(display_short)|uniprotkb:Gsta(gene name synonym)|uniprotkb:GST A4-4(gene name synonym)|uniprotkb:Glutathione S-transferase 5.7(gene name synonym)|uniprotkb:GST class-alpha member 4(gene name synonym)	psi-mi:mk09_mouse(display_long)|uniprotkb:Mapk9(gene name)|psi-mi:Mapk9(display_short)|uniprotkb:Jnk2(gene name synonym)|uniprotkb:Prkm9(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK2(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Desmots et al. (2005)	pubmed:16223495|imex:IM-10885|mint:MINT-5218005	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7842331|mint:MINT-68755|imex:IM-10885-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUST00000034903(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0009635"(response to herbicide)|go:"GO:0010043"(response to zinc ion)|go:"GO:0035094"(response to nicotine)|go:"GO:0071285"(cellular response to lithium ion)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P24472|rcsb pdb:1B48|rcsb pdb:1GUK|ensembl:ENSMUSG00000032348(gene)|refseq:NP_034487.2|mint:MINT-1487687(identity)	ensembl:ENSMUSG00000020366(gene)|ensembl:ENSMUST00000043321(transcript)|ensembl:ENSMUST00000178543(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0004672"(protein kinase activity)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010770"(positive regulation of cell morphogenesis involved in differentiation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031175"(neuron projection development)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0042493"|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048511"(rhythmic process)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061833"(protein localization to tricellular tight junction)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901485"(positive regulation of transcription factor catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321|reactome:R-MMU-450341|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0032722"(positive regulation of chemokine production)|refseq:NP_001157143.1|refseq:NP_001157144.1|refseq:NP_058657.1|refseq:NP_997575.2|ensembl:ENSMUSG00000020366|dip:DIP-31076N|mint:MINT-1487692(identity)	-	function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2005/11/01	2014/10/16	rogid:NOQwk+xfvdsLUtQjIujh63AclxA10090	rogid:m/9TybdDExPF8ah6GnnWDbHSgyA10090	intact-crc:DB2B365011172244|rigid:T1hGq3tcJ7aE7MewHhVSBndNU2k	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P24472	uniprotkb:Q61831	intact:EBI-7842269|ensembl:ENSMUSP00000034903|uniprotkb:Q9CQ81|uniprotkb:Q9CY87|uniprotkb:Q9CTY7|intact:MINT-1487605|uniprotkb:Q9D038	intact:EBI-400741|uniprotkb:Q9R0U6	psi-mi:gsta4_mouse(display_long)|uniprotkb:Gsta4(gene name)|psi-mi:Gsta4(display_short)|uniprotkb:Gsta(gene name synonym)|uniprotkb:GST A4-4(gene name synonym)|uniprotkb:Glutathione S-transferase 5.7(gene name synonym)|uniprotkb:GST class-alpha member 4(gene name synonym)	psi-mi:mk10_mouse(display_long)|uniprotkb:Mapk10(gene name)|psi-mi:Mapk10(display_short)|uniprotkb:Jnk3(gene name synonym)|uniprotkb:Prkm10(gene name synonym)|uniprotkb:Serk2(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK3(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 3(gene name synonym)|uniprotkb:MAP kinase p49 3F12(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Desmots et al. (2005)	pubmed:16223495|imex:IM-10885|mint:MINT-5218005	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7842382|mint:MINT-68756|imex:IM-10885-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUST00000034903(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0009635"(response to herbicide)|go:"GO:0010043"(response to zinc ion)|go:"GO:0035094"(response to nicotine)|go:"GO:0071285"(cellular response to lithium ion)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P24472|rcsb pdb:1B48|rcsb pdb:1GUK|ensembl:ENSMUSG00000032348(gene)|refseq:NP_034487.2|mint:MINT-1487729(identity)	interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_017176379.1|refseq:NP_001297615.1|refseq:XP_017176380.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0009416"(response to light stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321|reactome:R-MMU-450341|mint:MINT-1487734(identity)	-	function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2005/11/01	2014/10/16	rogid:NOQwk+xfvdsLUtQjIujh63AclxA10090	rogid:5x8VKNSD0AmjnO8BgrewNT2Ypb810090	intact-crc:5CE72293FC545834|rigid:dFq86X3y9LflzDixb7JfvGnR1RY	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)