#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P10687	uniprotkb:Q8TEW0	intact:EBI-7551252|intact:MINT-1342819	intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47	psi-mi:plcb1_rat(display_long)|uniprotkb:Plcb1(gene name)|psi-mi:Plcb1(display_short)|uniprotkb:Phospholipase C-beta-1(gene name synonym)|uniprotkb:PLC-154(gene name synonym)|uniprotkb:Phosphoinositide phospholipase C-beta-1(gene name synonym)|uniprotkb:Phospholipase C-I(gene name synonym)	psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cai et al. (2005)	pubmed:15782111|mint:MINT-5217607	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7551325|mint:MINT-62352	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR028400|interpro:IPR009535(Protein of unknown function DUF1154)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR037862|interpro:IPR035892|interpro:IPR014815(PLC-beta, C-terminal)|refseq:NP_001071109.1|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR017946|rgd:3344|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031161"(phosphatidylinositol catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032957"(inositol trisphosphate metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034284"(response to monosaccharide)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902618"(cellular response to fluoride)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905631"(cellular response to glyceraldehyde)|go:"GO:2000344"(positive regulation of acrosome reaction)|go:"GO:2000438"(negative regulation of monocyte extravasation)|go:"GO:2000560"(positive regulation of CD24 production)|refseq:XP_017446955.1|reactome:R-RNO-112043|reactome:R-RNO-1855204|reactome:R-RNO-399997|reactome:R-RNO-416476|reactome:R-RNO-434316|interpro:IPR042531|mint:MINT-1342883(identity)	interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N|mint:MINT-1342877(identity)	-	function:"The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/08/26	2014/10/16	rogid:BQurZ15kj2/MiOgZzdPzLLyUm6010116	rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606	intact-crc:72E980345E098441|rigid:pgIlUavYaHlsECrL4qKqqKYQshU	false	-	tag:?-?(MINT-1342878)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10687	uniprotkb:Q9NPB6	intact:EBI-7551252|intact:MINT-1342819	intact:EBI-81876|ensembl:ENSP00000219255|uniprotkb:O14911|uniprotkb:Q9NPJ7	psi-mi:plcb1_rat(display_long)|uniprotkb:Plcb1(gene name)|psi-mi:Plcb1(display_short)|uniprotkb:Phospholipase C-beta-1(gene name synonym)|uniprotkb:PLC-154(gene name synonym)|uniprotkb:Phosphoinositide phospholipase C-beta-1(gene name synonym)|uniprotkb:Phospholipase C-I(gene name synonym)	psi-mi:par6a_human(display_long)|uniprotkb:PARD6A(gene name)|psi-mi:PARD6A(display_short)|uniprotkb:PAR6A(gene name synonym)|uniprotkb:PAR6C(gene name synonym)|uniprotkb:Tax interaction protein 40(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cai et al. (2005)	pubmed:15782111|mint:MINT-5217607	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7551375|mint:MINT-62353	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR028400|interpro:IPR009535(Protein of unknown function DUF1154)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR037862|interpro:IPR035892|interpro:IPR014815(PLC-beta, C-terminal)|refseq:NP_001071109.1|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR017946|rgd:3344|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031161"(phosphatidylinositol catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032957"(inositol trisphosphate metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034284"(response to monosaccharide)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902618"(cellular response to fluoride)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905631"(cellular response to glyceraldehyde)|go:"GO:2000344"(positive regulation of acrosome reaction)|go:"GO:2000438"(negative regulation of monocyte extravasation)|go:"GO:2000560"(positive regulation of CD24 production)|refseq:XP_017446955.1|reactome:R-RNO-112043|reactome:R-RNO-1855204|reactome:R-RNO-399997|reactome:R-RNO-416476|reactome:R-RNO-434316|interpro:IPR042531|mint:MINT-1342896(identity)	ensembl:ENSG00000102981(gene)|ensembl:ENST00000219255(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016032"(viral process)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR034868|interpro:IPR034872|interpro:IPR036034|mint:Q9NPB6|rcsb pdb:1WMH|reactome:R-HSA-2173791|reactome:R-HSA-420029|reactome:R-HSA-4608870|reactome:R-HSA-9013148|go:"GO:0034451"(centriolar satellite)|reactome:R-HSA-9013149|refseq:NP_001032358.1|refseq:NP_058644.1|dip:DIP-31312N|mint:MINT-1342890(identity)	-	function:"The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/08/26	2014/10/16	rogid:BQurZ15kj2/MiOgZzdPzLLyUm6010116	rogid:QvPdZFaXbWyVMe/qycVjq8xtybY9606	intact-crc:7B52909F20E2F149|rigid:FWqW0/26KSyVJNhVxZ30OTChp2w	false	-	tag:?-?(MINT-1342891)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01970	uniprotkb:Q9NPB6	intact:EBI-4289548|uniprotkb:A5PKZ6|ensembl:ENSP00000279230|ensembl:ENSP00000443631|uniprotkb:G5E960|uniprotkb:Q8N1A4	intact:EBI-81876|ensembl:ENSP00000219255|uniprotkb:O14911|uniprotkb:Q9NPJ7	psi-mi:plcb3_human(display_long)|uniprotkb:PLCB3(gene name)|psi-mi:PLCB3(display_short)|uniprotkb:Phosphoinositide phospholipase C-beta-3(gene name synonym)|uniprotkb:Phospholipase C-beta-3(gene name synonym)	psi-mi:par6a_human(display_long)|uniprotkb:PARD6A(gene name)|psi-mi:PARD6A(display_short)|uniprotkb:PAR6A(gene name synonym)|uniprotkb:PAR6C(gene name synonym)|uniprotkb:Tax interaction protein 40(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cai et al. (2005)	pubmed:15782111|mint:MINT-5217607	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7551439|mint:MINT-62355	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000923.1|ensembl:ENSG00000149782(gene)|ensembl:ENST00000279230(transcript)|ensembl:ENST00000540288(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0099524"(postsynaptic cytosol)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR014815(PLC-beta, C-terminal)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|interpro:IPR017946|interpro:IPR035892|interpro:IPR037862|interpro:IPR042531|rcsb pdb:3OHM|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|reactome:R-HSA-112043|reactome:R-HSA-1855204|reactome:R-HSA-399997|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-418217|reactome:R-HSA-434316|reactome:R-HSA-500657|refseq:NP_001171812.1|refseq:NP_001303243.1|dip:DIP-41928N|mint:MINT-1342648(identity)	ensembl:ENSG00000102981(gene)|ensembl:ENST00000219255(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016032"(viral process)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR034868|interpro:IPR034872|interpro:IPR036034|mint:Q9NPB6|rcsb pdb:1WMH|reactome:R-HSA-2173791|reactome:R-HSA-420029|reactome:R-HSA-4608870|reactome:R-HSA-9013148|go:"GO:0034451"(centriolar satellite)|reactome:R-HSA-9013149|refseq:NP_001032358.1|refseq:NP_058644.1|dip:DIP-31312N|mint:MINT-1342642(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/08/26	2014/10/16	rogid:ilIX1O1btxVzzYNb7iW4dG+Yh789606	rogid:QvPdZFaXbWyVMe/qycVjq8xtybY9606	intact-crc:3B8F465705E0F8E1|rigid:6dStOM8TPP4g5grc0JAYbIUWzgc	false	-	tag:?-?(MINT-1342643)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01970	uniprotkb:Q8TEW0	intact:EBI-4289548|uniprotkb:A5PKZ6|ensembl:ENSP00000279230|ensembl:ENSP00000443631|uniprotkb:G5E960|uniprotkb:Q8N1A4	intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47	psi-mi:plcb3_human(display_long)|uniprotkb:PLCB3(gene name)|psi-mi:PLCB3(display_short)|uniprotkb:Phosphoinositide phospholipase C-beta-3(gene name synonym)|uniprotkb:Phospholipase C-beta-3(gene name synonym)	psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cai et al. (2005)	pubmed:15782111|mint:MINT-5217607	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7551407|mint:MINT-62354	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000923.1|ensembl:ENSG00000149782(gene)|ensembl:ENST00000279230(transcript)|ensembl:ENST00000540288(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0099524"(postsynaptic cytosol)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR014815(PLC-beta, C-terminal)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|interpro:IPR017946|interpro:IPR035892|interpro:IPR037862|interpro:IPR042531|rcsb pdb:3OHM|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|reactome:R-HSA-112043|reactome:R-HSA-1855204|reactome:R-HSA-399997|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-418217|reactome:R-HSA-434316|reactome:R-HSA-500657|refseq:NP_001171812.1|refseq:NP_001303243.1|dip:DIP-41928N|mint:MINT-1342763(identity)	interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N|mint:MINT-1342757(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/08/26	2014/10/16	rogid:ilIX1O1btxVzzYNb7iW4dG+Yh789606	rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606	intact-crc:BEB545227546D21E|rigid:frWoWcK03qQ2cFQk3z8SkjRtNOg	false	-	tag:?-?(MINT-1342758)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10687	uniprotkb:Q9NPB6	intact:EBI-7551252|intact:MINT-1342819	intact:EBI-81876|ensembl:ENSP00000219255|uniprotkb:O14911|uniprotkb:Q9NPJ7	psi-mi:plcb1_rat(display_long)|uniprotkb:Plcb1(gene name)|psi-mi:Plcb1(display_short)|uniprotkb:Phospholipase C-beta-1(gene name synonym)|uniprotkb:PLC-154(gene name synonym)|uniprotkb:Phosphoinositide phospholipase C-beta-1(gene name synonym)|uniprotkb:Phospholipase C-I(gene name synonym)	psi-mi:par6a_human(display_long)|uniprotkb:PARD6A(gene name)|psi-mi:PARD6A(display_short)|uniprotkb:PAR6A(gene name synonym)|uniprotkb:PAR6C(gene name synonym)|uniprotkb:Tax interaction protein 40(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2005)	pubmed:15782111|mint:MINT-5217607	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7551652|mint:MINT-62357	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR028400|interpro:IPR009535(Protein of unknown function DUF1154)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR037862|interpro:IPR035892|interpro:IPR014815(PLC-beta, C-terminal)|refseq:NP_001071109.1|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR017946|rgd:3344|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031161"(phosphatidylinositol catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032957"(inositol trisphosphate metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034284"(response to monosaccharide)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902618"(cellular response to fluoride)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905631"(cellular response to glyceraldehyde)|go:"GO:2000344"(positive regulation of acrosome reaction)|go:"GO:2000438"(negative regulation of monocyte extravasation)|go:"GO:2000560"(positive regulation of CD24 production)|refseq:XP_017446955.1|reactome:R-RNO-112043|reactome:R-RNO-1855204|reactome:R-RNO-399997|reactome:R-RNO-416476|reactome:R-RNO-434316|interpro:IPR042531|mint:MINT-1342832(identity)	ensembl:ENSG00000102981(gene)|ensembl:ENST00000219255(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016032"(viral process)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR034868|interpro:IPR034872|interpro:IPR036034|mint:Q9NPB6|rcsb pdb:1WMH|reactome:R-HSA-2173791|reactome:R-HSA-420029|reactome:R-HSA-4608870|reactome:R-HSA-9013148|go:"GO:0034451"(centriolar satellite)|reactome:R-HSA-9013149|refseq:NP_001032358.1|refseq:NP_058644.1|dip:DIP-31312N|mint:MINT-1342838(identity)	-	function:"The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2C F3C|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/08/26	2014/10/16	rogid:BQurZ15kj2/MiOgZzdPzLLyUm6010116	rogid:QvPdZFaXbWyVMe/qycVjq8xtybY9606	intact-crc:1FF6E9240A74B6E9|rigid:FWqW0/26KSyVJNhVxZ30OTChp2w	false	mutation decreasing interaction:1214-1216(MINT-1342833)	tag:?-?(MINT-1342839)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TEW0	uniprotkb:Q01970	intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47	intact:EBI-4289548|uniprotkb:A5PKZ6|ensembl:ENSP00000279230|ensembl:ENSP00000443631|uniprotkb:G5E960|uniprotkb:Q8N1A4	psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym)	psi-mi:plcb3_human(display_long)|uniprotkb:PLCB3(gene name)|psi-mi:PLCB3(display_short)|uniprotkb:Phosphoinositide phospholipase C-beta-3(gene name synonym)|uniprotkb:Phospholipase C-beta-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2005)	pubmed:15782111|mint:MINT-5217607	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7551670|mint:MINT-62358	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N|mint:MINT-1342853(identity)	refseq:NP_000923.1|ensembl:ENSG00000149782(gene)|ensembl:ENST00000279230(transcript)|ensembl:ENST00000540288(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0099524"(postsynaptic cytosol)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR014815(PLC-beta, C-terminal)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|interpro:IPR017946|interpro:IPR035892|interpro:IPR037862|interpro:IPR042531|rcsb pdb:3OHM|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|reactome:R-HSA-112043|reactome:R-HSA-1855204|reactome:R-HSA-399997|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-418217|reactome:R-HSA-434316|reactome:R-HSA-500657|refseq:NP_001171812.1|refseq:NP_001303243.1|dip:DIP-41928N|mint:MINT-1342847(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2C F3C|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/08/26	2014/10/16	rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606	rogid:ilIX1O1btxVzzYNb7iW4dG+Yh789606	intact-crc:E0ABFD09A91D6527|rigid:frWoWcK03qQ2cFQk3z8SkjRtNOg	false	tag:?-?(MINT-1342854)	mutation decreasing interaction:1232-1234(MINT-1342848)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P10687	uniprotkb:Q8TEW0	intact:EBI-7551252|intact:MINT-1342819	intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47	psi-mi:plcb1_rat(display_long)|uniprotkb:Plcb1(gene name)|psi-mi:Plcb1(display_short)|uniprotkb:Phospholipase C-beta-1(gene name synonym)|uniprotkb:PLC-154(gene name synonym)|uniprotkb:Phosphoinositide phospholipase C-beta-1(gene name synonym)|uniprotkb:Phospholipase C-I(gene name synonym)	psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2005)	pubmed:15782111|mint:MINT-5217607	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7551616|mint:MINT-62356	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR028400|interpro:IPR009535(Protein of unknown function DUF1154)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR037862|interpro:IPR035892|interpro:IPR014815(PLC-beta, C-terminal)|refseq:NP_001071109.1|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR017946|rgd:3344|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031161"(phosphatidylinositol catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032957"(inositol trisphosphate metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034284"(response to monosaccharide)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902618"(cellular response to fluoride)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905631"(cellular response to glyceraldehyde)|go:"GO:2000344"(positive regulation of acrosome reaction)|go:"GO:2000438"(negative regulation of monocyte extravasation)|go:"GO:2000560"(positive regulation of CD24 production)|refseq:XP_017446955.1|reactome:R-RNO-112043|reactome:R-RNO-1855204|reactome:R-RNO-399997|reactome:R-RNO-416476|reactome:R-RNO-434316|interpro:IPR042531|mint:MINT-1342862(identity)	interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N|mint:MINT-1342868(identity)	-	function:"The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2C F3C|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/08/26	2014/10/16	rogid:BQurZ15kj2/MiOgZzdPzLLyUm6010116	rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606	intact-crc:46202B927D49A3CF|rigid:pgIlUavYaHlsECrL4qKqqKYQshU	false	mutation decreasing interaction:1214-1216(MINT-1342863)	tag:?-?(MINT-1342869)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10687	uniprotkb:Q8TEW0	intact:EBI-7551252|intact:MINT-1342819	intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47	psi-mi:plcb1_rat(display_long)|uniprotkb:Plcb1(gene name)|psi-mi:Plcb1(display_short)|uniprotkb:Phospholipase C-beta-1(gene name synonym)|uniprotkb:PLC-154(gene name synonym)|uniprotkb:Phosphoinositide phospholipase C-beta-1(gene name synonym)|uniprotkb:Phospholipase C-I(gene name synonym)	psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2005)	pubmed:15782111|mint:MINT-5217607	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7551742|mint:MINT-62360	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR028400|interpro:IPR009535(Protein of unknown function DUF1154)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR037862|interpro:IPR035892|interpro:IPR014815(PLC-beta, C-terminal)|refseq:NP_001071109.1|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR017946|rgd:3344|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031161"(phosphatidylinositol catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032957"(inositol trisphosphate metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034284"(response to monosaccharide)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902618"(cellular response to fluoride)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1905631"(cellular response to glyceraldehyde)|go:"GO:2000344"(positive regulation of acrosome reaction)|go:"GO:2000438"(negative regulation of monocyte extravasation)|go:"GO:2000560"(positive regulation of CD24 production)|refseq:XP_017446955.1|reactome:R-RNO-112043|reactome:R-RNO-1855204|reactome:R-RNO-399997|reactome:R-RNO-416476|reactome:R-RNO-434316|interpro:IPR042531|mint:MINT-1342919(identity)	interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N|mint:MINT-1342923(identity)	-	function:"The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3A F3B|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/08/26	2014/10/16	rogid:BQurZ15kj2/MiOgZzdPzLLyUm6010116	rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606	intact-crc:1C9D7B72BE092C6B|rigid:pgIlUavYaHlsECrL4qKqqKYQshU	false	-	binding-associated region:271-359(MINT-1342924)|tag:?-?(MINT-1342927)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPB6	uniprotkb:Q01970	intact:EBI-81876|ensembl:ENSP00000219255|uniprotkb:O14911|uniprotkb:Q9NPJ7	intact:EBI-4289548|uniprotkb:A5PKZ6|ensembl:ENSP00000279230|ensembl:ENSP00000443631|uniprotkb:G5E960|uniprotkb:Q8N1A4	psi-mi:par6a_human(display_long)|uniprotkb:PARD6A(gene name)|psi-mi:PARD6A(display_short)|uniprotkb:PAR6A(gene name synonym)|uniprotkb:PAR6C(gene name synonym)|uniprotkb:Tax interaction protein 40(gene name synonym)	psi-mi:plcb3_human(display_long)|uniprotkb:PLCB3(gene name)|psi-mi:PLCB3(display_short)|uniprotkb:Phosphoinositide phospholipase C-beta-3(gene name synonym)|uniprotkb:Phospholipase C-beta-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2005)	pubmed:15782111|mint:MINT-5217607	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7551706|mint:MINT-62359	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102981(gene)|ensembl:ENST00000219255(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016032"(viral process)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR034868|interpro:IPR034872|interpro:IPR036034|mint:Q9NPB6|rcsb pdb:1WMH|reactome:R-HSA-2173791|reactome:R-HSA-420029|reactome:R-HSA-4608870|reactome:R-HSA-9013148|go:"GO:0034451"(centriolar satellite)|reactome:R-HSA-9013149|refseq:NP_001032358.1|refseq:NP_058644.1|dip:DIP-31312N|mint:MINT-1342778(identity)	refseq:NP_000923.1|ensembl:ENSG00000149782(gene)|ensembl:ENST00000279230(transcript)|ensembl:ENST00000540288(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0099524"(postsynaptic cytosol)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR014815(PLC-beta, C-terminal)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|interpro:IPR017946|interpro:IPR035892|interpro:IPR037862|interpro:IPR042531|rcsb pdb:3OHM|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|reactome:R-HSA-112043|reactome:R-HSA-1855204|reactome:R-HSA-399997|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-418217|reactome:R-HSA-434316|reactome:R-HSA-500657|refseq:NP_001171812.1|refseq:NP_001303243.1|dip:DIP-41928N|mint:MINT-1342772(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2C F3C|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/08/26	2014/10/16	rogid:QvPdZFaXbWyVMe/qycVjq8xtybY9606	rogid:ilIX1O1btxVzzYNb7iW4dG+Yh789606	intact-crc:0214285DDC7189C9|rigid:6dStOM8TPP4g5grc0JAYbIUWzgc	false	tag:?-?(MINT-1342779)	mutation decreasing interaction:1232-1234(MINT-1342773)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q01970	uniprotkb:Q8TEW0	intact:EBI-4289548|uniprotkb:A5PKZ6|ensembl:ENSP00000279230|ensembl:ENSP00000443631|uniprotkb:G5E960|uniprotkb:Q8N1A4	intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47	psi-mi:plcb3_human(display_long)|uniprotkb:PLCB3(gene name)|psi-mi:PLCB3(display_short)|uniprotkb:Phosphoinositide phospholipase C-beta-3(gene name synonym)|uniprotkb:Phospholipase C-beta-3(gene name synonym)	psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2005)	pubmed:15782111|mint:MINT-5217607	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7551844|mint:MINT-62362	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000923.1|ensembl:ENSG00000149782(gene)|ensembl:ENST00000279230(transcript)|ensembl:ENST00000540288(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0099524"(postsynaptic cytosol)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR014815(PLC-beta, C-terminal)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|interpro:IPR017946|interpro:IPR035892|interpro:IPR037862|interpro:IPR042531|rcsb pdb:3OHM|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|reactome:R-HSA-112043|reactome:R-HSA-1855204|reactome:R-HSA-399997|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-418217|reactome:R-HSA-434316|reactome:R-HSA-500657|refseq:NP_001171812.1|refseq:NP_001303243.1|dip:DIP-41928N|mint:MINT-1342787(identity)	interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N|mint:MINT-1342791(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3A F3B|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/08/26	2014/10/16	rogid:ilIX1O1btxVzzYNb7iW4dG+Yh789606	rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606	intact-crc:25B51C0D3D37C749|rigid:frWoWcK03qQ2cFQk3z8SkjRtNOg	false	-	tag:?-?(MINT-1342795)|binding-associated region:458-548(MINT-1342792)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01970	uniprotkb:Q8TEW0	intact:EBI-4289548|uniprotkb:A5PKZ6|ensembl:ENSP00000279230|ensembl:ENSP00000443631|uniprotkb:G5E960|uniprotkb:Q8N1A4	intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47	psi-mi:plcb3_human(display_long)|uniprotkb:PLCB3(gene name)|psi-mi:PLCB3(display_short)|uniprotkb:Phosphoinositide phospholipase C-beta-3(gene name synonym)|uniprotkb:Phospholipase C-beta-3(gene name synonym)	psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2005)	pubmed:15782111|mint:MINT-5217607	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7551808|mint:MINT-62361	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000923.1|ensembl:ENSG00000149782(gene)|ensembl:ENST00000279230(transcript)|ensembl:ENST00000540288(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0099524"(postsynaptic cytosol)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR014815(PLC-beta, C-terminal)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|interpro:IPR017946|interpro:IPR035892|interpro:IPR037862|interpro:IPR042531|rcsb pdb:3OHM|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|reactome:R-HSA-112043|reactome:R-HSA-1855204|reactome:R-HSA-399997|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-418217|reactome:R-HSA-434316|reactome:R-HSA-500657|refseq:NP_001171812.1|refseq:NP_001303243.1|dip:DIP-41928N|mint:MINT-1342903(identity)	interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N|mint:MINT-1342907(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3A F3B|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/08/26	2014/10/16	rogid:ilIX1O1btxVzzYNb7iW4dG+Yh789606	rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606	intact-crc:1D77CB18A2E08DEC|rigid:frWoWcK03qQ2cFQk3z8SkjRtNOg	false	-	binding-associated region:271-359(MINT-1342908)|tag:?-?(MINT-1342911)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TEW0	uniprotkb:Q01970	intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47	intact:EBI-4289548|uniprotkb:A5PKZ6|ensembl:ENSP00000279230|ensembl:ENSP00000443631|uniprotkb:G5E960|uniprotkb:Q8N1A4	psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym)	psi-mi:plcb3_human(display_long)|uniprotkb:PLCB3(gene name)|psi-mi:PLCB3(display_short)|uniprotkb:Phosphoinositide phospholipase C-beta-3(gene name synonym)|uniprotkb:Phospholipase C-beta-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2005)	pubmed:15782111|mint:MINT-5217607	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7551881|mint:MINT-62363	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N|mint:MINT-1342807(identity)	refseq:NP_000923.1|ensembl:ENSG00000149782(gene)|ensembl:ENST00000279230(transcript)|ensembl:ENST00000540288(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0099524"(postsynaptic cytosol)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR014815(PLC-beta, C-terminal)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|interpro:IPR017946|interpro:IPR035892|interpro:IPR037862|interpro:IPR042531|rcsb pdb:3OHM|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|reactome:R-HSA-112043|reactome:R-HSA-1855204|reactome:R-HSA-399997|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-418217|reactome:R-HSA-434316|reactome:R-HSA-500657|refseq:NP_001171812.1|refseq:NP_001303243.1|dip:DIP-41928N|mint:MINT-1342803(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3A F3B|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/08/26	2014/10/16	rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606	rogid:ilIX1O1btxVzzYNb7iW4dG+Yh789606	intact-crc:78BD9E09B23BC862|rigid:frWoWcK03qQ2cFQk3z8SkjRtNOg	false	tag:?-?(MINT-1342811)|binding-associated region:578-683(MINT-1342808)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)