#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B
uniprotkb:P03366 uniprotkb:P03366 intact:EBI-6164084|uniprotkb:P03368 intact:EBI-6164084|uniprotkb:P03368 psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0428"(imaging technique) Tachedjian et al. (2005) pubmed:15642347|imex:IM-11350|mint:MINT-5217452 taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7446601|mint:MINT-51600|imex:IM-11350-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215338(identity) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215327(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2B|comment:"The interaction is enhanced by addiction of EFV (efavirenz) in the medium. The interacting protein p66 is derived by the Pol polyprotein precursor that originates different proteins but it is not described in the UniProt database as a single protein."|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/04 2014/10/16 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 intact-crc:C432417190BC4553|rigid:JxpGLH20G0tyj/I6zR/sBxcBDqs false tag:?-?(MINT-1215343)|polyprotein fragment:600-1159(MINT-6741858)|binding-associated region:168-724(IPR002156) polyprotein fragment:600-1159(MINT-6741862)|tag:?-?(MINT-1215332)|binding-associated region:168-724(MINT-1215328) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P03366 uniprotkb:P03366 intact:EBI-6164084|uniprotkb:P03368 intact:EBI-6164084|uniprotkb:P03368 psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0428"(imaging technique) Tachedjian et al. (2005) pubmed:15642347|imex:IM-11350|mint:MINT-5217452 taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7446643|mint:MINT-51601|imex:IM-11350-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215265(identity) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215255(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2B|comment:"The interaction is enhanced by addiction of EFV (efavirenz) in the medium. The interacting protein p51 is derived by the Pol polyprotein precursor that originates different proteins but it is not described in the UniProt database as a single protein."|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/04 2014/10/16 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 intact-crc:8763987950D74B34|rigid:JxpGLH20G0tyj/I6zR/sBxcBDqs false tag:?-?(MINT-1215269)|binding-associated region:168-607(MINT-1215266)|polyprotein fragment:600-1039(MINT-6741870) binding-associated region:168-607(MINT-1215256)|polyprotein fragment:600-1039(MINT-6741866)|tag:?-?(MINT-1215259) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P03366 uniprotkb:P03366 intact:EBI-6164084|uniprotkb:P03368 intact:EBI-6164084|uniprotkb:P03368 psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0428"(imaging technique) Tachedjian et al. (2005) pubmed:15642347|imex:IM-11350|mint:MINT-5217452 taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7446699|mint:MINT-51602|imex:IM-11350-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215289(identity) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215279(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3B|comment:"The interaction is enhanced by addiction of EFV (efavirenz) in the medium. The interacting protein p51 is derived by the Pol polyprotein precursor that originates different proteins but it is not described in the UniProt database as a single protein."|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/04 2014/10/16 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 intact-crc:675184CF8BCDE12E|rigid:JxpGLH20G0tyj/I6zR/sBxcBDqs false polyprotein fragment:600-1039(MINT-6741878)|tag:?-?(MINT-1215293)|binding-associated region:168-607(MINT-1215290) tag:?-?(MINT-1215283)|polyprotein fragment:600-1039(MINT-6741874)|binding-associated region:168-607(MINT-1215280) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P03366 uniprotkb:P03366 intact:EBI-6164084|uniprotkb:P03368 intact:EBI-6164084|uniprotkb:P03368 psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0428"(imaging technique) Tachedjian et al. (2005) pubmed:15642347|imex:IM-11350|mint:MINT-5217452 taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7446739|mint:MINT-51603|imex:IM-11350-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215204(identity) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215215(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3A|comment:"The interaction is enhanced by addiction of EFV (efavirenz) in the medium. The interacting protein p66 is derived by the Pol polyprotein precursor that originates different proteins but it is not described in the UniProt database as a single protein."|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/04 2014/10/16 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 intact-crc:CF0B25AA64B39F90|rigid:JxpGLH20G0tyj/I6zR/sBxcBDqs false tag:?-?(MINT-1215209)|polyprotein fragment:600-1159(MINT-6741850)|binding-associated region:168-724(MINT-1215205) polyprotein fragment:600-1159(MINT-6741854)|binding-associated region:168-724(IPR002156)|tag:?-?(MINT-1215220) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P03366 uniprotkb:P03366 intact:EBI-6164084|uniprotkb:P03368 intact:EBI-6164084|uniprotkb:P03368 psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tachedjian et al. (2005) pubmed:15642347|imex:IM-11350|mint:MINT-5217452 taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7446831|mint:MINT-51591|imex:IM-11350-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215232(identity) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215242(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1A|comment:"The interaction is enhanced by addiction of EFV (efavirenz) in the medium.
The interacting proteins p66 and p51 are derived by the same precursor, Pol polyprotein, but they are not described in the UniProt database as single proteins.
In this experiment the bait is p66, the prey is p51"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/03/04 2014/10/16 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 intact-crc:8A11A00E37EDFD2B|rigid:JxpGLH20G0tyj/I6zR/sBxcBDqs false binding-associated region:168-724(MINT-1215233)|polyprotein fragment:600-1159(MINT-6741823)|tag:?-?(MINT-1215237) tag:?-?(MINT-1215246)|polyprotein fragment:600-1039(MINT-6741838)|binding-associated region:168-607(MINT-1215243) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P03366 uniprotkb:P03366 intact:EBI-6164084|uniprotkb:P03368 intact:EBI-6164084|uniprotkb:P03368 psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tachedjian et al. (2005) pubmed:15642347|imex:IM-11350|mint:MINT-5217452 taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7446872|mint:MINT-51596|imex:IM-11350-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215303(identity) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215313(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1A|comment:"The interaction is enhanced by addiction of EFV (efavirenz) in the medium.
The interacting protein p66 is derived by the Pol polyprotein precursor that originates different proteins but it is not described in the UniProt database as a single protein. In this experiment the bait is p66, the prey is p66"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/03/04 2014/10/16 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 intact-crc:74593429D6F043D6|rigid:JxpGLH20G0tyj/I6zR/sBxcBDqs false polyprotein fragment:600-1159(MINT-6741826)|binding-associated region:168-724(MINT-1215304)|tag:?-?(MINT-1215308) tag:?-?(MINT-1215318)|binding-associated region:168-724(MINT-1215314)|polyprotein fragment:600-1159(MINT-6741830) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P03366 uniprotkb:P03366 intact:EBI-6164084|uniprotkb:P03368 intact:EBI-6164084|uniprotkb:P03368 psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:pol_hv1b1(display_long)|uniprotkb:gag-pol(gene name)|psi-mi:gag-pol(display_short)|uniprotkb:Pr160Gag-Pol(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tachedjian et al. (2005) pubmed:15642347|imex:IM-11350|mint:MINT-5217452 taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") taxid:11678(hv1b1)|taxid:11678("Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7446929|mint:MINT-51597|imex:IM-11350-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215362(identity) rcsb pdb:3ZPS|rcsb pdb:3ZPT|rcsb pdb:3ZPU|rcsb pdb:4MFB|rcsb pdb:6WAZ|rcsb pdb:6WB0|rcsb pdb:6WB1|rcsb pdb:6WB2|rcsb pdb:6X47|rcsb pdb:6X49|rcsb pdb:6X4A|rcsb pdb:6X4B|rcsb pdb:6X4C|rcsb pdb:6X4D|rcsb pdb:6X4E|rcsb pdb:6X4F|rcsb pdb:7KJV|rcsb pdb:7KJW|rcsb pdb:7KJX|rcsb pdb:7KWU|rcsb pdb:4LSL|rcsb pdb:4LSN|rcsb pdb:4O44|rcsb pdb:4ZIP|rcsb pdb:4ZLS|rcsb pdb:5C24|rcsb pdb:5C25|rcsb pdb:5C42|rcsb pdb:4O4G|rcsb pdb:4U8W|rcsb pdb:6PRF|rcsb pdb:4COE|rcsb pdb:4CP7|rcsb pdb:4WE1|rcsb pdb:5TER|rcsb pdb:6ELI|interpro:IPR036397|interpro:IPR036862|interpro:IPR036875|rcsb pdb:5TUQ|rcsb pdb:5ULT|rcsb pdb:5UOV|rcsb pdb:5UPZ|rcsb pdb:5UV5|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VQQ|rcsb pdb:5VQR|rcsb pdb:5VQS|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0003964"(RNA-directed DNA polymerase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004533"(exoribonuclease H activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0015074"(DNA integration)|go:"GO:0016020"(membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039651"(induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044826"(viral genome integration into host DNA)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0072494"(host multivesicular body)|go:"GO:0075732"(viral penetration into host nucleus)|go:"GO:0075713"(establishment of integrated proviral latency)|rcsb pdb:5W5W|rcsb pdb:4CPQ|rcsb pdb:4CPR|rcsb pdb:4CPS|rcsb pdb:4CPT|rcsb pdb:4CPU|rcsb pdb:4CPW|rcsb pdb:4CPX|rcsb pdb:5FDL|rcsb pdb:5HBM|rcsb pdb:5HLF|rcsb pdb:5VQT|rcsb pdb:5VQU|rcsb pdb:5VQV|rcsb pdb:5VQW|rcsb pdb:5VQX|rcsb pdb:5VQY|rcsb pdb:5VQZ|rcsb pdb:5D3G|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|rcsb pdb:7AHX|rcsb pdb:7AID|rcsb pdb:7AIF|rcsb pdb:7AIG|rcsb pdb:7AII|rcsb pdb:7AIJ|rcsb pdb:7KRC|rcsb pdb:7KRD|rcsb pdb:7KRE|rcsb pdb:7KRF|rcsb pdb:4OJR|rcsb pdb:4PQU|rcsb pdb:4PUO|rcsb pdb:4PWD|rcsb pdb:4Q0B|rcsb pdb:4QAG|rcsb pdb:4R5P|rcsb pdb:5AH7|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TW3|rcsb pdb:3KLG|rcsb pdb:3KLH|rcsb pdb:3KLI|rcsb pdb:3NDT|rcsb pdb:3NU3|rcsb pdb:3NU4|rcsb pdb:3NU5|rcsb pdb:3NU6|rcsb pdb:3NU9|rcsb pdb:3NUJ|rcsb pdb:3NUO|rcsb pdb:3OK9|rcsb pdb:3PSU|rcsb pdb:3QAA|rcsb pdb:3QLH|rcsb pdb:3QO9|rcsb pdb:3TKG|rcsb pdb:3TKW|rcsb pdb:3TL9|rcsb pdb:3TLH|rcsb pdb:3V4I|rcsb pdb:3V6D|rcsb pdb:3V81|rcsb pdb:6D0D|rcsb pdb:6D0E|rcsb pdb:2JZW|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001037(Integrase, C-terminal, retroviral)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR003308(Integrase, N-terminal zinc-binding domain)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010659(Reverse transcriptase connection)|interpro:IPR010661(Reverse transcriptase thumb)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR018061|interpro:IPR021109|rcsb pdb:1A9M|rcsb pdb:1AJV|rcsb pdb:1AJX|rcsb pdb:1AXA|rcsb pdb:1BQM|rcsb pdb:1BQN|rcsb pdb:1D4H|rcsb pdb:1D4I|rcsb pdb:1D4J|rcsb pdb:1DLO|rcsb pdb:1DW6|rcsb pdb:1EBK|rcsb pdb:1EBW|rcsb pdb:1EBY|rcsb pdb:1EBZ|rcsb pdb:1EC0|rcsb pdb:1EC1|rcsb pdb:1EC2|rcsb pdb:1EC3|rcsb pdb:1EET|rcsb pdb:1G35|rcsb pdb:1GNM|rcsb pdb:1GNN|rcsb pdb:1GNO|rcsb pdb:1HAR|rcsb pdb:1HBV|rcsb pdb:1HEF|rcsb pdb:1HEG|rcsb pdb:1HIH|rcsb pdb:1HMV|rcsb pdb:1HNI|rcsb pdb:1HNV|rcsb pdb:1HOS|rcsb pdb:1HPS|rcsb pdb:1HPZ|rcsb pdb:1HQE|rcsb pdb:1HQU|rcsb pdb:1HRH|rcsb pdb:1HTE|rcsb pdb:1HTF|rcsb pdb:1HTG|rcsb pdb:1HVI|rcsb pdb:1HVK|rcsb pdb:1HVP|rcsb pdb:1HVU|rcsb pdb:1HYS|rcsb pdb:1IKV|rcsb pdb:1IKW|rcsb pdb:1IKX|rcsb pdb:1IKY|rcsb pdb:1J5O|rcsb pdb:1KJH|rcsb pdb:1MER|rcsb pdb:1MES|rcsb pdb:1MET|rcsb pdb:1MEU|rcsb pdb:1N5Y|rcsb pdb:1N6Q|rcsb pdb:1NPA|rcsb pdb:1NPV|rcsb pdb:1NPW|rcsb pdb:1QE1|rcsb pdb:1QMC|rcsb pdb:1R0A|rcsb pdb:1RDH|rcsb pdb:1RTD|rcsb pdb:1RVL|rcsb pdb:1RVM|rcsb pdb:1RVN|rcsb pdb:1RVO|rcsb pdb:1RVP|rcsb pdb:1RVQ|rcsb pdb:1RVR|rcsb pdb:1S6P|rcsb pdb:1S6Q|rcsb pdb:1S9E|rcsb pdb:1S9G|rcsb pdb:1SBG|rcsb pdb:1SUQ|rcsb pdb:1SV5|rcsb pdb:1T03|rcsb pdb:1T05|rcsb pdb:1T7K|rcsb pdb:1TV6|rcsb pdb:1TVR|rcsb pdb:1UWB|rcsb pdb:1W5V|rcsb pdb:1W5W|rcsb pdb:1W5X|rcsb pdb:1W5Y|rcsb pdb:1YT9|rcsb pdb:1ZP8|rcsb pdb:1ZPA|rcsb pdb:1ZSF|rcsb pdb:1ZSR|rcsb pdb:2AQU|rcsb pdb:2B5J|rcsb pdb:2B6A|rcsb pdb:2BAN|rcsb pdb:2BBB|rcsb pdb:2BE2|rcsb pdb:2EXF|rcsb pdb:2G69|rcsb pdb:2HB3|rcsb pdb:2HMI|rcsb pdb:2HNZ|rcsb pdb:2HS1|rcsb pdb:2HS2|rcsb pdb:2I4D|rcsb pdb:2I4U|rcsb pdb:2I4V|rcsb pdb:2I4W|rcsb pdb:2I4X|rcsb pdb:2I5J|rcsb pdb:2IAJ|rcsb pdb:2IC3|rcsb pdb:2IDW|rcsb pdb:2IEO|rcsb pdb:2L45|rcsb pdb:2L46|rcsb pdb:2L4L|rcsb pdb:2UXZ|rcsb pdb:2UY0|rcsb pdb:2VG5|rcsb pdb:2VG6|rcsb pdb:2VG7|rcsb pdb:2X4U|rcsb pdb:2YKM|rcsb pdb:2YKN|rcsb pdb:2ZD1|rcsb pdb:2ZE2|rcsb pdb:3AVI|rcsb pdb:3BGR|rcsb pdb:3DLK|rcsb pdb:3GGA|rcsb pdb:3GGV|rcsb pdb:3GGX|rcsb pdb:3HVT|rcsb pdb:3IG1|rcsb pdb:3IRX|rcsb pdb:3IS9|rcsb pdb:3ISN|rcsb pdb:3ITH|rcsb pdb:3JSM|rcsb pdb:3JYT|rcsb pdb:3K2P|rcsb pdb:3K4V|rcsb pdb:3KLE|rcsb pdb:3KLF|rcsb pdb:4G1Q|rcsb pdb:4ICL|rcsb pdb:4ID5|rcsb pdb:4IDK|rcsb pdb:4IFV|rcsb pdb:4IFY|rcsb pdb:4IG0|rcsb pdb:4IG3|rcsb pdb:6O9E|rcsb pdb:4DG1|rcsb pdb:4KFB|rcsb pdb:5HP1|rcsb pdb:5HRO|rcsb pdb:5I3U|rcsb pdb:5I42|rcsb pdb:5J1E|rcsb pdb:4H4M|rcsb pdb:4H4O|rcsb pdb:4I2P|rcsb pdb:4I2Q|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4RW4|rcsb pdb:4RW6|rcsb pdb:4RW7|rcsb pdb:4RW8|rcsb pdb:4RW9|rcsb pdb:5AGZ|rcsb pdb:5AH6|rcsb pdb:5AH8|rcsb pdb:5AH9|rcsb pdb:5AHA|rcsb pdb:5AHB|rcsb pdb:5AHC|rcsb pdb:5TXL|rcsb pdb:5TXM|rcsb pdb:5TXN|rcsb pdb:5TXO|rcsb pdb:5TXP|rcsb pdb:4YE3|rcsb pdb:4YHQ|rcsb pdb:4KO0|rcsb pdb:4KKO|rcsb pdb:5BRY|rcsb pdb:5BS4|rcsb pdb:5CYM|rcsb pdb:5CYQ|rcsb pdb:5JFP|rcsb pdb:5JFU|rcsb pdb:5JG1|interpro:IPR034170|rcsb pdb:6C8X|rcsb pdb:6C8Y|rcsb pdb:6HAK|rcsb pdb:6OE3|rcsb pdb:6AMO|rcsb pdb:6AN2|rcsb pdb:6AN8|rcsb pdb:6ANQ|rcsb pdb:6AOC|rcsb pdb:6ASW|rcsb pdb:6AVM|rcsb pdb:6AVT|rcsb pdb:6C0J|rcsb pdb:6C0K|rcsb pdb:6C0L|rcsb pdb:6C0N|rcsb pdb:6C0O|rcsb pdb:6C0P|rcsb pdb:6C0R|rcsb pdb:6CGF|rcsb pdb:6DUF|rcsb pdb:6DUG|rcsb pdb:6DUH|rcsb pdb:5UFZ|rcsb pdb:6B19|rcsb pdb:6BZ2|rcsb pdb:5OI2|rcsb pdb:5OI3|rcsb pdb:5OI5|rcsb pdb:5OI8|rcsb pdb:5OIA|rcsb pdb:5YOJ|interpro:IPR043502|rcsb pdb:6DTW|rcsb pdb:6DTX|rcsb pdb:6ECL|rcsb pdb:6OUN|rcsb pdb:6O48|interpro:IPR043128|rcsb pdb:6UL5|rcsb pdb:6KMP|rcsb pdb:6VUG|mint:MINT-1215353(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1A|comment:"The interaction is enhanced by addiction of EFV (efavirenz) in the medium.
The interacting protein p51 is derived by the Pol polyprotein precursor that originates different proteins but it is not described in the UniProt database as a single protein.
In this experiment the bait is p51, the prey is p51"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/03/04 2014/10/16 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 rogid:Mp/WUBSNFoTdVaUPeE/ZUtGI50E11678 intact-crc:17874FBF8EA084B1|rigid:JxpGLH20G0tyj/I6zR/sBxcBDqs false binding-associated region:168-607(MINT-1215363)|tag:?-?(MINT-1215366)|polyprotein fragment:600-1039(MINT-6741846) binding-associated region:168-607(MINT-1215354)|polyprotein fragment:600-1039(MINT-6741842)|tag:?-?(MINT-1215357) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)