#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7Z2E3 uniprotkb:P18887 intact:EBI-847814|uniprotkb:A8MTN4|uniprotkb:Q5T781|uniprotkb:Q7Z2F3|uniprotkb:Q7Z336|uniprotkb:Q7Z5R5|uniprotkb:Q7Z6V7|uniprotkb:Q7Z6V8|uniprotkb:Q9NXM5|uniprotkb:Q0P662|uniprotkb:Q5T784|uniprotkb:D3DRK9|uniprotkb:D3DRL0|uniprotkb:Q5T782|uniprotkb:Q6JV81|uniprotkb:Q6JV82|uniprotkb:Q6JV85 intact:EBI-947466|uniprotkb:Q9HCB1|uniprotkb:Q6IBS4|ensembl:ENSP00000262887 psi-mi:aptx_human(display_long)|uniprotkb:Forkhead-associated domain histidine triad-like protein(gene name synonym)|uniprotkb:APTX(gene name)|psi-mi:APTX(display_short)|uniprotkb:AXA1(gene name synonym) psi-mi:xrcc1_human(display_long)|uniprotkb:XRCC1(gene name)|psi-mi:XRCC1(display_short)|uniprotkb:X-ray repair cross-complementing protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Clements et al. (2004) pubmed:15380105|mint:MINT-5217198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7322332|mint:MINT-51153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006716854.1|refseq:XP_006716855.1|refseq:NP_001182177.1|refseq:NP_001182178.1|refseq:NP_001182179.1|refseq:NP_001182180.1|refseq:NP_001182181.1|refseq:NP_001182183.1|refseq:NP_778239.1|refseq:NP_778243.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR008984(SMAD/FHA domain)|refseq:XP_016870326.1|interpro:IPR026963|interpro:IPR032566|interpro:IPR036265|refseq:XP_011516240.1|refseq:XP_011516241.1|mint:Q7Z2E3|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041388|go:"GO:0000012"(single strand break repair)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006266"(DNA ligation)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008967"(phosphoglycolate phosphatase activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033699"(DNA 5'-adenosine monophosphate hydrolase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0046403"(polynucleotide 3'-phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0120108"(DNA-3'-diphospho-5'-guanosine diphosphatase)|go:"GO:1990165"(single-strand break-containing DNA binding)|rcsb pdb:3KT9|rcsb pdb:4NDF|rcsb pdb:4NDG|rcsb pdb:4NDH|rcsb pdb:4NDI|rcsb pdb:6CVO|rcsb pdb:6CVP|rcsb pdb:6CVQ|rcsb pdb:6CVR|rcsb pdb:6CVS|rcsb pdb:6CVT|mint:MINT-1205636(identity) refseq:NP_006288.2|dip:DIP-39067N|ensembl:ENSG00000073050(gene)|ensembl:ENST00000262887(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0010033"(response to organic substance)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0032356"(oxidized DNA binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904877"(positive regulation of DNA ligase activity)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990599"(3' overhang single-stranded DNA endodeoxyribonuclease activity)|interpro:IPR001357(BRCT)|interpro:IPR002706(DNA-repair protein Xrcc1, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036420|mint:P18887|rcsb pdb:1CDZ|rcsb pdb:1XNA|rcsb pdb:1XNT|rcsb pdb:2D8M|rcsb pdb:2W3O|rcsb pdb:3K75|rcsb pdb:3K77|rcsb pdb:3LQC|rcsb pdb:5E6Q|rcsb pdb:5W7X|rcsb pdb:5W7Y|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210|mint:MINT-1205642(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/01/24 2014/10/16 rogid:+F8ouBUeaA4oDe1S6zOGADQfCxQ9606 rogid:96hETrBzHYhHX9FC5dZpKnFcjDg9606 intact-crc:953E8E81407F2295|rigid:RQi90iOY8otECNmE3sX6R0MX6tk false tag:?-?(MINT-1205637) tag:?-?(MINT-1205643) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13426 uniprotkb:Q7Z2E3 intact:EBI-717592|uniprotkb:Q9BS72|uniprotkb:Q9UP94|uniprotkb:A8K3X4|ensembl:ENSP00000342011|ensembl:ENSP00000421491 intact:EBI-847814|uniprotkb:A8MTN4|uniprotkb:Q5T781|uniprotkb:Q7Z2F3|uniprotkb:Q7Z336|uniprotkb:Q7Z5R5|uniprotkb:Q7Z6V7|uniprotkb:Q7Z6V8|uniprotkb:Q9NXM5|uniprotkb:Q0P662|uniprotkb:Q5T784|uniprotkb:D3DRK9|uniprotkb:D3DRL0|uniprotkb:Q5T782|uniprotkb:Q6JV81|uniprotkb:Q6JV82|uniprotkb:Q6JV85 psi-mi:xrcc4_human(display_long)|uniprotkb:X-ray repair cross-complementing protein 4(gene name synonym)|uniprotkb:XRCC4(gene name)|psi-mi:XRCC4(display_short) psi-mi:aptx_human(display_long)|uniprotkb:Forkhead-associated domain histidine triad-like protein(gene name synonym)|uniprotkb:APTX(gene name)|psi-mi:APTX(display_short)|uniprotkb:AXA1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Clements et al. (2004) pubmed:15380105|mint:MINT-5217198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7322350|mint:MINT-51155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003392.1|refseq:NP_071801.1|refseq:NP_072044.1|refseq:NP_001304941.1|refseq:NP_001304942.1|refseq:XP_011541928.1|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010165"(response to X-ray)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0070975"(FHA domain binding)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1990166"(protein localization to site of double-strand break)|interpro:IPR009089(DNA double-strand break repair and VJ recombination XRCC4, N-terminal)|interpro:IPR010585(DNA double-strand break repair and VJ recombination XRCC4)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR038051|mint:Q13426|rcsb pdb:1FU1|rcsb pdb:1IK9|rcsb pdb:3II6|rcsb pdb:3MUD|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|go:"GO:0005737"(cytoplasm)|rcsb pdb:3W03|rcsb pdb:4XA4|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ4|rcsb pdb:5E50|rcsb pdb:5WJ7|rcsb pdb:5WLZ|rcsb pdb:6ABO|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7M3P|reactome:R-HSA-164843|reactome:R-HSA-3108214|reactome:R-HSA-5693571|ensembl:ENSG00000152422(gene)|ensembl:ENST00000338635(transcript)|ensembl:ENST00000511817(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-37957N|mint:MINT-1205627(identity) refseq:XP_006716854.1|refseq:XP_006716855.1|refseq:NP_001182177.1|refseq:NP_001182178.1|refseq:NP_001182179.1|refseq:NP_001182180.1|refseq:NP_001182181.1|refseq:NP_001182183.1|refseq:NP_778239.1|refseq:NP_778243.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR008984(SMAD/FHA domain)|refseq:XP_016870326.1|interpro:IPR026963|interpro:IPR032566|interpro:IPR036265|refseq:XP_011516240.1|refseq:XP_011516241.1|mint:Q7Z2E3|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041388|go:"GO:0000012"(single strand break repair)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006266"(DNA ligation)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008967"(phosphoglycolate phosphatase activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033699"(DNA 5'-adenosine monophosphate hydrolase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0046403"(polynucleotide 3'-phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0120108"(DNA-3'-diphospho-5'-guanosine diphosphatase)|go:"GO:1990165"(single-strand break-containing DNA binding)|rcsb pdb:3KT9|rcsb pdb:4NDF|rcsb pdb:4NDG|rcsb pdb:4NDH|rcsb pdb:4NDI|rcsb pdb:6CVO|rcsb pdb:6CVP|rcsb pdb:6CVQ|rcsb pdb:6CVR|rcsb pdb:6CVS|rcsb pdb:6CVT|mint:MINT-1205621(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/01/24 2014/10/16 rogid:qWdX2yBKXcwYG7vQpss9MIaFWU89606 rogid:+F8ouBUeaA4oDe1S6zOGADQfCxQ9606 intact-crc:904425ECA27EA0B9|rigid:5QCJbW1vaTXme0yxPzW7FuVrdEo false fusion protein:?-?(MINT-1205628) fusion protein:?-?(MINT-1205622) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z2E3 uniprotkb:P18887 intact:EBI-847814|uniprotkb:A8MTN4|uniprotkb:Q5T781|uniprotkb:Q7Z2F3|uniprotkb:Q7Z336|uniprotkb:Q7Z5R5|uniprotkb:Q7Z6V7|uniprotkb:Q7Z6V8|uniprotkb:Q9NXM5|uniprotkb:Q0P662|uniprotkb:Q5T784|uniprotkb:D3DRK9|uniprotkb:D3DRL0|uniprotkb:Q5T782|uniprotkb:Q6JV81|uniprotkb:Q6JV82|uniprotkb:Q6JV85 intact:EBI-947466|uniprotkb:Q9HCB1|uniprotkb:Q6IBS4|ensembl:ENSP00000262887 psi-mi:aptx_human(display_long)|uniprotkb:Forkhead-associated domain histidine triad-like protein(gene name synonym)|uniprotkb:APTX(gene name)|psi-mi:APTX(display_short)|uniprotkb:AXA1(gene name synonym) psi-mi:xrcc1_human(display_long)|uniprotkb:XRCC1(gene name)|psi-mi:XRCC1(display_short)|uniprotkb:X-ray repair cross-complementing protein 1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Clements et al. (2004) pubmed:15380105|mint:MINT-5217198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7322376|mint:MINT-51154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006716854.1|refseq:XP_006716855.1|refseq:NP_001182177.1|refseq:NP_001182178.1|refseq:NP_001182179.1|refseq:NP_001182180.1|refseq:NP_001182181.1|refseq:NP_001182183.1|refseq:NP_778239.1|refseq:NP_778243.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR008984(SMAD/FHA domain)|refseq:XP_016870326.1|interpro:IPR026963|interpro:IPR032566|interpro:IPR036265|refseq:XP_011516240.1|refseq:XP_011516241.1|mint:Q7Z2E3|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041388|go:"GO:0000012"(single strand break repair)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006266"(DNA ligation)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008967"(phosphoglycolate phosphatase activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033699"(DNA 5'-adenosine monophosphate hydrolase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0046403"(polynucleotide 3'-phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0120108"(DNA-3'-diphospho-5'-guanosine diphosphatase)|go:"GO:1990165"(single-strand break-containing DNA binding)|rcsb pdb:3KT9|rcsb pdb:4NDF|rcsb pdb:4NDG|rcsb pdb:4NDH|rcsb pdb:4NDI|rcsb pdb:6CVO|rcsb pdb:6CVP|rcsb pdb:6CVQ|rcsb pdb:6CVR|rcsb pdb:6CVS|rcsb pdb:6CVT|mint:MINT-1205677(identity) refseq:NP_006288.2|dip:DIP-39067N|ensembl:ENSG00000073050(gene)|ensembl:ENST00000262887(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0010033"(response to organic substance)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0032356"(oxidized DNA binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904877"(positive regulation of DNA ligase activity)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990599"(3' overhang single-stranded DNA endodeoxyribonuclease activity)|interpro:IPR001357(BRCT)|interpro:IPR002706(DNA-repair protein Xrcc1, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036420|mint:P18887|rcsb pdb:1CDZ|rcsb pdb:1XNA|rcsb pdb:1XNT|rcsb pdb:2D8M|rcsb pdb:2W3O|rcsb pdb:3K75|rcsb pdb:3K77|rcsb pdb:3LQC|rcsb pdb:5E6Q|rcsb pdb:5W7X|rcsb pdb:5W7Y|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210|mint:MINT-1205671(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/01/24 2014/10/16 rogid:+F8ouBUeaA4oDe1S6zOGADQfCxQ9606 rogid:96hETrBzHYhHX9FC5dZpKnFcjDg9606 intact-crc:A4ED3139D2A4A8B9|rigid:RQi90iOY8otECNmE3sX6R0MX6tk false tag:?-?(MINT-1205681)|binding-associated region:38-87(MINT-1205678) tag:?-?(MINT-1205672) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13426 uniprotkb:Q7Z2E3 intact:EBI-717592|uniprotkb:Q9BS72|uniprotkb:Q9UP94|uniprotkb:A8K3X4|ensembl:ENSP00000342011|ensembl:ENSP00000421491 intact:EBI-847814|uniprotkb:A8MTN4|uniprotkb:Q5T781|uniprotkb:Q7Z2F3|uniprotkb:Q7Z336|uniprotkb:Q7Z5R5|uniprotkb:Q7Z6V7|uniprotkb:Q7Z6V8|uniprotkb:Q9NXM5|uniprotkb:Q0P662|uniprotkb:Q5T784|uniprotkb:D3DRK9|uniprotkb:D3DRL0|uniprotkb:Q5T782|uniprotkb:Q6JV81|uniprotkb:Q6JV82|uniprotkb:Q6JV85 psi-mi:xrcc4_human(display_long)|uniprotkb:X-ray repair cross-complementing protein 4(gene name synonym)|uniprotkb:XRCC4(gene name)|psi-mi:XRCC4(display_short) psi-mi:aptx_human(display_long)|uniprotkb:Forkhead-associated domain histidine triad-like protein(gene name synonym)|uniprotkb:APTX(gene name)|psi-mi:APTX(display_short)|uniprotkb:AXA1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Clements et al. (2004) pubmed:15380105|mint:MINT-5217198 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7322399|mint:MINT-51156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003392.1|refseq:NP_071801.1|refseq:NP_072044.1|refseq:NP_001304941.1|refseq:NP_001304942.1|refseq:XP_011541928.1|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010165"(response to X-ray)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0070975"(FHA domain binding)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1990166"(protein localization to site of double-strand break)|interpro:IPR009089(DNA double-strand break repair and VJ recombination XRCC4, N-terminal)|interpro:IPR010585(DNA double-strand break repair and VJ recombination XRCC4)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR038051|mint:Q13426|rcsb pdb:1FU1|rcsb pdb:1IK9|rcsb pdb:3II6|rcsb pdb:3MUD|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|go:"GO:0005737"(cytoplasm)|rcsb pdb:3W03|rcsb pdb:4XA4|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ4|rcsb pdb:5E50|rcsb pdb:5WJ7|rcsb pdb:5WLZ|rcsb pdb:6ABO|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7M3P|reactome:R-HSA-164843|reactome:R-HSA-3108214|reactome:R-HSA-5693571|ensembl:ENSG00000152422(gene)|ensembl:ENST00000338635(transcript)|ensembl:ENST00000511817(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-37957N|mint:MINT-1205662(identity) refseq:XP_006716854.1|refseq:XP_006716855.1|refseq:NP_001182177.1|refseq:NP_001182178.1|refseq:NP_001182179.1|refseq:NP_001182180.1|refseq:NP_001182181.1|refseq:NP_001182183.1|refseq:NP_778239.1|refseq:NP_778243.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR008984(SMAD/FHA domain)|refseq:XP_016870326.1|interpro:IPR026963|interpro:IPR032566|interpro:IPR036265|refseq:XP_011516240.1|refseq:XP_011516241.1|mint:Q7Z2E3|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041388|go:"GO:0000012"(single strand break repair)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006266"(DNA ligation)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008967"(phosphoglycolate phosphatase activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033699"(DNA 5'-adenosine monophosphate hydrolase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0046403"(polynucleotide 3'-phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0120108"(DNA-3'-diphospho-5'-guanosine diphosphatase)|go:"GO:1990165"(single-strand break-containing DNA binding)|rcsb pdb:3KT9|rcsb pdb:4NDF|rcsb pdb:4NDG|rcsb pdb:4NDH|rcsb pdb:4NDI|rcsb pdb:6CVO|rcsb pdb:6CVP|rcsb pdb:6CVQ|rcsb pdb:6CVR|rcsb pdb:6CVS|rcsb pdb:6CVT|mint:MINT-1205653(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/01/24 2014/10/16 rogid:qWdX2yBKXcwYG7vQpss9MIaFWU89606 rogid:+F8ouBUeaA4oDe1S6zOGADQfCxQ9606 intact-crc:8989A4FAC52D534F|rigid:5QCJbW1vaTXme0yxPzW7FuVrdEo false tag:?-?(MINT-1205663) tag:?-?(MINT-1205657)|binding-associated region:38-87(MINT-1205654) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)