#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q79V62 uniprotkb:Q79V60 intact:EBI-701584|uniprotkb:Q8RR35|ensemblbacteria:BAC08033 intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035 psi-mi:kaia_theeb(display_long)|uniprotkb:kaiA(gene name)|psi-mi:kaiA(display_short)|uniprotkb:tlr0481(locus name) psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short) psi-mi:"MI:0077"(nuclear magnetic resonance) Vakonakis et al. (2004) pubmed:15256595 taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-701767|rcsb pdb:1suy - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_681271.1|refseq:WP_011056332.1|dip:DIP-29355N|mint:Q79V62|ensemblbacteria:BAC08033(gene)|ensemblbacteria:BAC08033(transcript)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042802"(identical protein binding)|interpro:IPR011006(CheY-like)|interpro:IPR011648(KaiA)|interpro:IPR017944|interpro:IPR020844|interpro:IPR020856|rcsb pdb:1Q6A|rcsb pdb:1Q6B|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:1V2Z|rcsb pdb:5JWR refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61 - crc64:D3B0DCBE8A580B4E crc64:34E4CDF9DE9C1824 comment:Average minimized structure|complex-properties:KaiA fragment dimerizes along the c-terminal half of the long alpha4 helix by using primarily coiled-coil hydrophobic interactions with alpha4'. The two KaiC peptides bound to KaiA dimer have an extended L-shaped conformation. The dimerization of KaiA looks necessary for KaiC peptides binding because each chain makes extensive contact with KaiA.|dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/20 2014/10/16 rogid:CeRDujd+nzKBpU7pTDOvj5aG1aQ197221 rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221 intact-crc:22B554744F306CFF|rigid:z1+X3JbI7AV4LMiQo0zHCO5Aa9c false sufficient binding region:181-283|binding-associated region:249-249|binding-associated region:249-249|binding-associated region:242-242|binding-associated region:239-239|binding-associated region:267-267|binding-associated region:247-247|binding-associated region:253-253|binding-associated region:254-254|binding-associated region:206-206|binding-associated region:245-245|binding-associated region:274-274|binding-associated region:271-271|binding-associated region:235-235 sufficient binding region:?-?|binding-associated region:501-501|binding-associated region:502-502|binding-associated region:503-503|binding-associated region:503-503|binding-associated region:511-511|binding-associated region:491-491|binding-associated region:495-495|binding-associated region:496-496|binding-associated region:497-497|binding-associated region:502-502|binding-associated region:511-511|binding-associated region:512-512|binding-associated region:514-514 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q79V62 uniprotkb:Q79V60 intact:EBI-701584|uniprotkb:Q8RR35|ensemblbacteria:BAC08033 intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035 psi-mi:kaia_theeb(display_long)|uniprotkb:kaiA(gene name)|psi-mi:kaiA(display_short)|uniprotkb:tlr0481(locus name) psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short) psi-mi:"MI:0077"(nuclear magnetic resonance) Vakonakis et al. (2004) pubmed:15256595 taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-703973|rcsb pdb:1sv1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_681271.1|refseq:WP_011056332.1|dip:DIP-29355N|mint:Q79V62|ensemblbacteria:BAC08033(gene)|ensemblbacteria:BAC08033(transcript)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042802"(identical protein binding)|interpro:IPR011006(CheY-like)|interpro:IPR011648(KaiA)|interpro:IPR017944|interpro:IPR020844|interpro:IPR020856|rcsb pdb:1Q6A|rcsb pdb:1Q6B|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:1V2Z|rcsb pdb:5JWR refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61 - crc64:D3B0DCBE8A580B4E crc64:34E4CDF9DE9C1824 comment:25 structure ensemble|complex-properties:KaiA fragment dimerizes along the c-terminal half of the long alpha4 helix by using primarily coiled-coil hydrophobic interactions with alpha4'. The two KaiC peptides bound to KaiA dimer have an extended L-shaped conformation. The dimerization of KaiA looks necessary for KaiC peptides binding because each chain makes extensive contact with KaiA.|dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/20 2014/10/16 rogid:CeRDujd+nzKBpU7pTDOvj5aG1aQ197221 rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221 intact-crc:F6D56EE6294E89AF|rigid:z1+X3JbI7AV4LMiQo0zHCO5Aa9c false binding-associated region:249-249|binding-associated region:242-242|binding-associated region:239-239|binding-associated region:267-267|binding-associated region:247-247|binding-associated region:253-253|binding-associated region:254-254|binding-associated region:206-206|binding-associated region:245-245|binding-associated region:271-271|binding-associated region:274-274|binding-associated region:235-235|sufficient binding region:181-283 binding-associated region:511-511|binding-associated region:491-491|binding-associated region:495-495|binding-associated region:496-496|binding-associated region:497-497|binding-associated region:512-512|binding-associated region:514-514|sufficient binding region:?-?|binding-associated region:501-501|binding-associated region:502-502|binding-associated region:503-503|binding-associated region:503-503 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q79V60 uniprotkb:Q79V62 intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035 intact:EBI-701584|uniprotkb:Q8RR35|ensemblbacteria:BAC08033 psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short) psi-mi:kaia_theeb(display_long)|uniprotkb:kaiA(gene name)|psi-mi:kaiA(display_short)|uniprotkb:tlr0481(locus name) psi-mi:"MI:0077"(nuclear magnetic resonance) Vakonakis et al. (2004) pubmed:15256595 taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-701820 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61 refseq:NP_681271.1|refseq:WP_011056332.1|dip:DIP-29355N|mint:Q79V62|ensemblbacteria:BAC08033(gene)|ensemblbacteria:BAC08033(transcript)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042802"(identical protein binding)|interpro:IPR011006(CheY-like)|interpro:IPR011648(KaiA)|interpro:IPR017944|interpro:IPR020844|interpro:IPR020856|rcsb pdb:1Q6A|rcsb pdb:1Q6B|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:1V2Z|rcsb pdb:5JWR - crc64:34E4CDF9DE9C1824 crc64:D3B0DCBE8A580B4E dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/20 2014/10/16 rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221 rogid:CeRDujd+nzKBpU7pTDOvj5aG1aQ197221 intact-crc:FF0844EC28BDC649|rigid:z1+X3JbI7AV4LMiQo0zHCO5Aa9c false sufficient binding region:?-?|tag:n-n sufficient binding region:181-283|15n label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q79V60 uniprotkb:Q79V62 intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035 intact:EBI-701584|uniprotkb:Q8RR35|ensemblbacteria:BAC08033 psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short) psi-mi:kaia_theeb(display_long)|uniprotkb:kaiA(gene name)|psi-mi:kaiA(display_short)|uniprotkb:tlr0481(locus name) psi-mi:"MI:0077"(nuclear magnetic resonance) Vakonakis et al. (2004) pubmed:15256595 taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-701838 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61 refseq:NP_681271.1|refseq:WP_011056332.1|dip:DIP-29355N|mint:Q79V62|ensemblbacteria:BAC08033(gene)|ensemblbacteria:BAC08033(transcript)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042802"(identical protein binding)|interpro:IPR011006(CheY-like)|interpro:IPR011648(KaiA)|interpro:IPR017944|interpro:IPR020844|interpro:IPR020856|rcsb pdb:1Q6A|rcsb pdb:1Q6B|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:1V2Z|rcsb pdb:5JWR - crc64:34E4CDF9DE9C1824 crc64:D3B0DCBE8A580B4E dataset:Cyanobacteria - Interaction dataset based on Cyanobacteria proteins and related species taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/20 2014/10/16 rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221 rogid:CeRDujd+nzKBpU7pTDOvj5aG1aQ197221 intact-crc:4BCFF17C309D31FE|rigid:z1+X3JbI7AV4LMiQo0zHCO5Aa9c false sufficient binding region:?-? sufficient binding region:181-283|15n label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)