#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q07817-1	uniprotkb:Q16611	intact:EBI-287195|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|intact:EBI-8058735|intact:MINT-89566|intact:EBI-8058554|intact:EBI-8058512|intact:EBI-8058443	intact:EBI-519866|ensembl:ENSP00000363591|uniprotkb:Q92533|uniprotkb:Q6I9T6|uniprotkb:C0H5Y7	psi-mi:q07817-1(display_long)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:Bcl-xL(isoform synonym)	psi-mi:bak_human(display_long)|uniprotkb:Apoptosis regulator BAK(gene name synonym)|uniprotkb:Bcl-2-like protein 7(gene name synonym)|uniprotkb:BAK1(gene name)|psi-mi:BAK1(display_short)|uniprotkb:BAK(gene name synonym)|uniprotkb:BCL2L7(gene name synonym)|uniprotkb:CDN1(gene name synonym)	psi-mi:"MI:0099"(scintillation proximity assay)	Whitfield et al. (2003)	pubmed:14596824	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-701216	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78035(bclx_human)|ensembl:ENSG00000171552(gene)|ensembl:ENST00000678563(transcript)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)	refseq:NP_001179.1|ensembl:ENSG00000030110(gene)|ensembl:ENST00000374467(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002352"(B cell negative selection)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009620"(response to fungus)|go:"GO:0010046"(response to mycotoxin)|go:"GO:0010225"(response to UV-C)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051400"(BH domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060068"(vagina development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097145"(BAK complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR026308|interpro:IPR036834|mint:Q16611|rcsb pdb:1BXL|rcsb pdb:2IMS|rcsb pdb:2IMT|rcsb pdb:2JBY|rcsb pdb:2JCN|rcsb pdb:2LP8|rcsb pdb:2M5B|rcsb pdb:2XPX|rcsb pdb:2YV6|rcsb pdb:3I1H|rcsb pdb:3QBR|rcsb pdb:4D2L|rcsb pdb:4U2U|rcsb pdb:4U2V|rcsb pdb:4UF1|rcsb pdb:5AJK|rcsb pdb:5FMI|rcsb pdb:5FMK|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX1|rcsb pdb:6ODH|rcsb pdb:6UXM|rcsb pdb:6UXN|rcsb pdb:6UXO|rcsb pdb:6UXP|rcsb pdb:6UXQ|rcsb pdb:6UXR|rcsb pdb:7K02|rcsb pdb:7OFM|rcsb pdb:7OFO|reactome:R-HSA-111452|reactome:R-HSA-111457|reactome:R-HSA-5620971|refseq:XP_011513081.1|dip:DIP-935N	go:"GO:0051434"(BH3 domain binding)	-	-	inhibition:By HRK or BIM, which bind to BCL-XL incompetition to HRK|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/19	2014/10/16	rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606	rogid:F13a6H/g/tv/Pr90ehCDePpcSB49606	intact-crc:D29D3FFA1938A601|rigid:Vsl19lBLoL75CYE+wO3EE44R3hE	false	his tag:n-n|binding-associated region:3-212	binding-associated region:72-87(IPR000712)|biotin tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43521	uniprotkb:Q07817-1	intact:EBI-526406|uniprotkb:Q0MSE7|uniprotkb:Q0MSE8|uniprotkb:Q0MSE9|uniprotkb:Q53R28|uniprotkb:Q6JTU6|uniprotkb:Q6T851|uniprotkb:Q6TE14|uniprotkb:Q6TE15|uniprotkb:Q6TE16|uniprotkb:Q6V402|uniprotkb:A8K2W2|uniprotkb:Q8WYL6|uniprotkb:Q8WYL7|uniprotkb:Q8WYL8|uniprotkb:Q8WYL9|uniprotkb:Q8WYM0|uniprotkb:Q8WYM1|uniprotkb:O43522|intact:EBI-1002160|ensembl:ENSP00000376943	intact:EBI-287195|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|intact:EBI-8058735|intact:MINT-89566|intact:EBI-8058554|intact:EBI-8058512|intact:EBI-8058443	psi-mi:b2l11_human(display_long)|uniprotkb:BCL2L11(gene name)|psi-mi:BCL2L11(display_short)|uniprotkb:BIM(gene name synonym)|uniprotkb:Bcl2-interacting mediator of cell death(gene name synonym)	psi-mi:q07817-1(display_long)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:Bcl-xL(isoform synonym)	psi-mi:"MI:0099"(scintillation proximity assay)	Whitfield et al. (2003)	pubmed:14596824	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-701297	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191035.1|refseq:NP_001191036.1|refseq:NP_001191037.1|refseq:NP_001191038.1|refseq:NP_001191039.1|refseq:NP_001191040.1|refseq:NP_001191041.1|refseq:NP_001191042.1|refseq:NP_006529.1|refseq:NP_619527.1|refseq:NP_619528.1|refseq:NP_619529.1|refseq:NP_619530.1|refseq:NP_619531.1|refseq:NP_619532.1|refseq:NP_619533.1|refseq:NP_996885.1|refseq:NP_996886.1|ensembl:ENSG00000153094(gene)|ensembl:ENST00000393256(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001822"(kidney development)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007127"(meiosis I)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0012505"(endomembrane system)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035148"(tube formation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097140"(BIM-BCL-xl complex)|go:"GO:0097141"(BIM-BCL-2 complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-6802952|reactome:R-HSA-8862803|reactome:R-HSA-8952158|reactome:R-HSA-9607240|reactome:R-HSA-9614657|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014771(Apoptosis, Bim N-terminal)|interpro:IPR015040(Bcl-x interacting)|interpro:IPR017288(Apoptosis, Bcl-2-like protein 11)|mint:O43521|rcsb pdb:1F95|rcsb pdb:2K7W|rcsb pdb:2NL9|rcsb pdb:2V6Q|rcsb pdb:2VM6|rcsb pdb:2WH6|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:3D7V|rcsb pdb:3FDL|rcsb pdb:3IO8|rcsb pdb:3IO9|rcsb pdb:3KJ0|rcsb pdb:3KJ1|rcsb pdb:3KJ2|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4B4S|rcsb pdb:4D2M|rcsb pdb:4QVF|rcsb pdb:4UF3|rcsb pdb:4YJ4|rcsb pdb:4ZIE|rcsb pdb:4ZIF|rcsb pdb:4ZIH|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5C3G|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX2|rcsb pdb:5VX3|rcsb pdb:5WOS|rcsb pdb:6QFI|rcsb pdb:6RJP|rcsb pdb:6TQQ|rcsb pdb:6UA3|rcsb pdb:6UAB|rcsb pdb:6VBX|rcsb pdb:6X8O|reactome:R-HSA-111446|dip:DIP-29185N	intact:EBI-78035(bclx_human)|ensembl:ENSG00000171552(gene)|ensembl:ENST00000678563(transcript)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)	go:"GO:0051434"(BH3 domain binding)	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/19	2014/10/16	rogid:YvDxFP1kVEoSiz67PVpE4ZM5wWI9606	rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606	intact-crc:171F9400E31678D3|rigid:Za29MZzAlAIfxbgAv8/q+ePX9T0	false	binding-associated region:142-166(IPR000712)|biotin tag:n-n	his tag:n-n|binding-associated region:3-212	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00198	uniprotkb:Q07817-1	intact:EBI-701322|ensembl:ENSP00000257572	intact:EBI-287195|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|intact:EBI-8058735|intact:MINT-89566|intact:EBI-8058554|intact:EBI-8058512|intact:EBI-8058443	psi-mi:hrk_human(display_long)|uniprotkb:Neuronal death protein DP5(gene name synonym)|uniprotkb:BH3-interacting domain-containing protein 3(gene name synonym)|uniprotkb:HRK(gene name)|psi-mi:HRK(display_short)|uniprotkb:BID3(gene name synonym)	psi-mi:q07817-1(display_long)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:Bcl-xL(isoform synonym)	psi-mi:"MI:0099"(scintillation proximity assay)	Whitfield et al. (2003)	pubmed:14596824	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-701309	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003797.1|refseq:XP_016875635.1|ensembl:ENSG00000135116(gene)|ensembl:ENST00000257572(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|interpro:IPR017249(Apoptosis, activator harakiri)|interpro:IPR020728|rcsb pdb:2L58|rcsb pdb:2L5B|rcsb pdb:6XY4	intact:EBI-78035(bclx_human)|ensembl:ENSG00000171552(gene)|ensembl:ENST00000678563(transcript)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)	go:"GO:0051434"(BH3 domain binding)	-	-	inhibition:By BAK or BIM, which bind to BCL-XL incompetition to HRK|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/19	2014/10/16	rogid:FKS9Mt5Ycxm5pl5//XAYXLc6cCI9606	rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606	intact-crc:78C9F38738D4F741|rigid:apyzVaaqRbpBY7TsMy/yXyMLULo	false	biotin tag:n-n|binding-associated region:27-51(IPR000712)	his tag:n-n|binding-associated region:3-212	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07817-1	uniprotkb:Q16611	intact:EBI-287195|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|intact:EBI-8058735|intact:MINT-89566|intact:EBI-8058554|intact:EBI-8058512|intact:EBI-8058443	intact:EBI-519866|ensembl:ENSP00000363591|uniprotkb:Q92533|uniprotkb:Q6I9T6|uniprotkb:C0H5Y7	psi-mi:q07817-1(display_long)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:Bcl-xL(isoform synonym)	psi-mi:bak_human(display_long)|uniprotkb:Apoptosis regulator BAK(gene name synonym)|uniprotkb:Bcl-2-like protein 7(gene name synonym)|uniprotkb:BAK1(gene name)|psi-mi:BAK1(display_short)|uniprotkb:BAK(gene name synonym)|uniprotkb:BCL2L7(gene name synonym)|uniprotkb:CDN1(gene name synonym)	psi-mi:"MI:0510"(homogeneous time resolved fluorescence)	Whitfield et al. (2003)	pubmed:14596824	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-701466	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-78035(bclx_human)|ensembl:ENSG00000171552(gene)|ensembl:ENST00000678563(transcript)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)	refseq:NP_001179.1|ensembl:ENSG00000030110(gene)|ensembl:ENST00000374467(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002352"(B cell negative selection)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009620"(response to fungus)|go:"GO:0010046"(response to mycotoxin)|go:"GO:0010225"(response to UV-C)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051400"(BH domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060068"(vagina development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097145"(BAK complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR026308|interpro:IPR036834|mint:Q16611|rcsb pdb:1BXL|rcsb pdb:2IMS|rcsb pdb:2IMT|rcsb pdb:2JBY|rcsb pdb:2JCN|rcsb pdb:2LP8|rcsb pdb:2M5B|rcsb pdb:2XPX|rcsb pdb:2YV6|rcsb pdb:3I1H|rcsb pdb:3QBR|rcsb pdb:4D2L|rcsb pdb:4U2U|rcsb pdb:4U2V|rcsb pdb:4UF1|rcsb pdb:5AJK|rcsb pdb:5FMI|rcsb pdb:5FMK|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX1|rcsb pdb:6ODH|rcsb pdb:6UXM|rcsb pdb:6UXN|rcsb pdb:6UXO|rcsb pdb:6UXP|rcsb pdb:6UXQ|rcsb pdb:6UXR|rcsb pdb:7K02|rcsb pdb:7OFM|rcsb pdb:7OFO|reactome:R-HSA-111452|reactome:R-HSA-111457|reactome:R-HSA-5620971|refseq:XP_011513081.1|dip:DIP-935N	go:"GO:0051434"(BH3 domain binding)	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/19	2014/10/16	rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606	rogid:F13a6H/g/tv/Pr90ehCDePpcSB49606	intact-crc:10942D7D195BEE86|rigid:Vsl19lBLoL75CYE+wO3EE44R3hE	false	binding-associated region:3-212|his tag:n-n	binding-associated region:72-87|biotin tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43521	uniprotkb:Q07817-1	intact:EBI-526406|uniprotkb:Q0MSE7|uniprotkb:Q0MSE8|uniprotkb:Q0MSE9|uniprotkb:Q53R28|uniprotkb:Q6JTU6|uniprotkb:Q6T851|uniprotkb:Q6TE14|uniprotkb:Q6TE15|uniprotkb:Q6TE16|uniprotkb:Q6V402|uniprotkb:A8K2W2|uniprotkb:Q8WYL6|uniprotkb:Q8WYL7|uniprotkb:Q8WYL8|uniprotkb:Q8WYL9|uniprotkb:Q8WYM0|uniprotkb:Q8WYM1|uniprotkb:O43522|intact:EBI-1002160|ensembl:ENSP00000376943	intact:EBI-287195|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|intact:EBI-8058735|intact:MINT-89566|intact:EBI-8058554|intact:EBI-8058512|intact:EBI-8058443	psi-mi:b2l11_human(display_long)|uniprotkb:BCL2L11(gene name)|psi-mi:BCL2L11(display_short)|uniprotkb:BIM(gene name synonym)|uniprotkb:Bcl2-interacting mediator of cell death(gene name synonym)	psi-mi:q07817-1(display_long)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:Bcl-xL(isoform synonym)	psi-mi:"MI:0510"(homogeneous time resolved fluorescence)	Whitfield et al. (2003)	pubmed:14596824	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-701497	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191035.1|refseq:NP_001191036.1|refseq:NP_001191037.1|refseq:NP_001191038.1|refseq:NP_001191039.1|refseq:NP_001191040.1|refseq:NP_001191041.1|refseq:NP_001191042.1|refseq:NP_006529.1|refseq:NP_619527.1|refseq:NP_619528.1|refseq:NP_619529.1|refseq:NP_619530.1|refseq:NP_619531.1|refseq:NP_619532.1|refseq:NP_619533.1|refseq:NP_996885.1|refseq:NP_996886.1|ensembl:ENSG00000153094(gene)|ensembl:ENST00000393256(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001822"(kidney development)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007127"(meiosis I)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0012505"(endomembrane system)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035148"(tube formation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097140"(BIM-BCL-xl complex)|go:"GO:0097141"(BIM-BCL-2 complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-6802952|reactome:R-HSA-8862803|reactome:R-HSA-8952158|reactome:R-HSA-9607240|reactome:R-HSA-9614657|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014771(Apoptosis, Bim N-terminal)|interpro:IPR015040(Bcl-x interacting)|interpro:IPR017288(Apoptosis, Bcl-2-like protein 11)|mint:O43521|rcsb pdb:1F95|rcsb pdb:2K7W|rcsb pdb:2NL9|rcsb pdb:2V6Q|rcsb pdb:2VM6|rcsb pdb:2WH6|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:3D7V|rcsb pdb:3FDL|rcsb pdb:3IO8|rcsb pdb:3IO9|rcsb pdb:3KJ0|rcsb pdb:3KJ1|rcsb pdb:3KJ2|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4B4S|rcsb pdb:4D2M|rcsb pdb:4QVF|rcsb pdb:4UF3|rcsb pdb:4YJ4|rcsb pdb:4ZIE|rcsb pdb:4ZIF|rcsb pdb:4ZIH|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5C3G|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX2|rcsb pdb:5VX3|rcsb pdb:5WOS|rcsb pdb:6QFI|rcsb pdb:6RJP|rcsb pdb:6TQQ|rcsb pdb:6UA3|rcsb pdb:6UAB|rcsb pdb:6VBX|rcsb pdb:6X8O|reactome:R-HSA-111446|dip:DIP-29185N	intact:EBI-78035(bclx_human)|ensembl:ENSG00000171552(gene)|ensembl:ENST00000678563(transcript)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)	go:"GO:0051434"(BH3 domain binding)	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/19	2014/10/16	rogid:YvDxFP1kVEoSiz67PVpE4ZM5wWI9606	rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606	intact-crc:7DED400718F6C3BE|rigid:Za29MZzAlAIfxbgAv8/q+ePX9T0	false	biotin tag:n-n|binding-associated region:142-166	his tag:n-n|binding-associated region:3-212	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)