#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P07196	uniprotkb:Q13614	intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169	intact:EBI-475631|uniprotkb:Q9UPS9|ensembl:ENSP00000345752|uniprotkb:A6NN98	psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym)	psi-mi:mtmr2_human(display_long)|uniprotkb:MTMR2(gene name)|psi-mi:MTMR2(display_short)|uniprotkb:KIAA1073(gene name synonym)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Previtali et al. (2003)	pubmed:12837694	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-475642	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244	refseq:XP_006718998.1|refseq:XP_006718999.1|refseq:XP_016874006.1|refseq:XP_016874007.1|refseq:XP_006718997.1|refseq:NP_958435.1|refseq:NP_958438.1|refseq:NP_057240.3|refseq:NP_001230500.1|ensembl:ENSG00000087053(gene)|ensembl:ENST00000346299(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032288"(myelin assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048666"(neuron development)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:2000645"(negative regulation of receptor catabolic process)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR004182(GRAM)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR030564|mint:Q13614|rcsb pdb:1LW3|rcsb pdb:1M7R|rcsb pdb:1ZSQ|rcsb pdb:1ZVR|rcsb pdb:5GNH|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660516|reactome:R-HSA-1660517|interpro:IPR029021|refseq:XP_005274431.1|refseq:XP_005274432.1	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/01/14	2014/10/16	rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606	rogid:NIG+mKVVhMYEsCU20hoVInG8EOw9606	intact-crc:F9421DDFC7C5C341|rigid:ch6kW/4DiXhAHCBag0SjD2H8glk	false	binding-associated region:251-431	binding-associated region:1-643|mutation:320-320	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07196	uniprotkb:Q13614	intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169	intact:EBI-475631|uniprotkb:Q9UPS9|ensembl:ENSP00000345752|uniprotkb:A6NN98	psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym)	psi-mi:mtmr2_human(display_long)|uniprotkb:MTMR2(gene name)|psi-mi:MTMR2(display_short)|uniprotkb:KIAA1073(gene name synonym)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Previtali et al. (2003)	pubmed:12837694	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-475668	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244	refseq:XP_006718998.1|refseq:XP_006718999.1|refseq:XP_016874006.1|refseq:XP_016874007.1|refseq:XP_006718997.1|refseq:NP_958435.1|refseq:NP_958438.1|refseq:NP_057240.3|refseq:NP_001230500.1|ensembl:ENSG00000087053(gene)|ensembl:ENST00000346299(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032288"(myelin assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048666"(neuron development)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:2000645"(negative regulation of receptor catabolic process)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR004182(GRAM)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR030564|mint:Q13614|rcsb pdb:1LW3|rcsb pdb:1M7R|rcsb pdb:1ZSQ|rcsb pdb:1ZVR|rcsb pdb:5GNH|reactome:R-HSA-1483248|reactome:R-HSA-1660499|reactome:R-HSA-1660516|reactome:R-HSA-1660517|interpro:IPR029021|refseq:XP_005274431.1|refseq:XP_005274432.1	-	-	-	comment:lysates were immunoprecipated with anti-FLAG and immunoblotted with anti-NF-L.	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/01/14	2014/10/16	rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606	rogid:NIG+mKVVhMYEsCU20hoVInG8EOw9606	intact-crc:6EBA10456BDD21E5|rigid:ch6kW/4DiXhAHCBag0SjD2H8glk	false	-	flag tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)