#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6P0Q8 uniprotkb:Q9BYE9 intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671 intact:EBI-493793|uniprotkb:Q9NXP8|uniprotkb:A1L3U4|uniprotkb:A6NC80|intact:EBI-28985604|ensembl:ENSP00000261944|ensembl:ENSP00000424565 psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short) psi-mi:cdhr2_human(display_long)|uniprotkb:PCLKC(gene name synonym)|uniprotkb:Protocadherin LKC(gene name synonym)|uniprotkb:CDHR2(gene name)|psi-mi:CDHR2(display_short)|uniprotkb:PCDH24(gene name synonym)|uniprotkb:Protocadherin-24(gene name synonym) psi-mi:"MI:0018"(two hybrid) Okazaki et al. (2002) pubmed:12117771 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-493811 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site) refseq:NP_001165447.1|refseq:NP_060145.3|ensembl:ENSP00000424565|ensembl:ENSP00000261944|ensembl:ENSG00000074276(gene)|ensembl:ENST00000261944(transcript)|ensembl:ENST00000510636(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005903"(brush border)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060243"(negative regulation of cell growth involved in contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090675"(intermicrovillar adhesion)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR039808|rcsb pdb:5CZR|go:"GO:0031528"(microvillus membrane) - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/02/22 2014/10/16 rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606 rogid:hrWy8QtZUYFgmvMQ96IwOm+F3X09606 intact-crc:BCF70760E777ADE6|rigid:XpUA4aWwpoWqkqJynxgNqOq4dYc false binding-associated region:1032-1294(IPR001478) binding-associated region:1177-1310|mutation decreasing interaction:1310-1310 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P0Q8 uniprotkb:Q9BYE9 intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671 intact:EBI-493793|uniprotkb:Q9NXP8|uniprotkb:A1L3U4|uniprotkb:A6NC80|intact:EBI-28985604|ensembl:ENSP00000261944|ensembl:ENSP00000424565 psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short) psi-mi:cdhr2_human(display_long)|uniprotkb:PCLKC(gene name synonym)|uniprotkb:Protocadherin LKC(gene name synonym)|uniprotkb:CDHR2(gene name)|psi-mi:CDHR2(display_short)|uniprotkb:PCDH24(gene name synonym)|uniprotkb:Protocadherin-24(gene name synonym) psi-mi:"MI:0018"(two hybrid) Okazaki et al. (2002) pubmed:12117771 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-493776 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site) refseq:NP_001165447.1|refseq:NP_060145.3|ensembl:ENSP00000424565|ensembl:ENSP00000261944|ensembl:ENSG00000074276(gene)|ensembl:ENST00000261944(transcript)|ensembl:ENST00000510636(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005903"(brush border)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060243"(negative regulation of cell growth involved in contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090675"(intermicrovillar adhesion)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR039808|rcsb pdb:5CZR|go:"GO:0031528"(microvillus membrane) - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/02/22 2014/10/16 rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606 rogid:hrWy8QtZUYFgmvMQ96IwOm+F3X09606 intact-crc:B5F70569C68804A0|rigid:XpUA4aWwpoWqkqJynxgNqOq4dYc false - binding-associated region:1177-1310 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BYE9 uniprotkb:Q6P0Q8 intact:EBI-493793|uniprotkb:Q9NXP8|uniprotkb:A1L3U4|uniprotkb:A6NC80|intact:EBI-28985604|ensembl:ENSP00000261944|ensembl:ENSP00000424565 intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671 psi-mi:cdhr2_human(display_long)|uniprotkb:PCLKC(gene name synonym)|uniprotkb:Protocadherin LKC(gene name synonym)|uniprotkb:CDHR2(gene name)|psi-mi:CDHR2(display_short)|uniprotkb:PCDH24(gene name synonym)|uniprotkb:Protocadherin-24(gene name synonym) psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Okazaki et al. (2002) pubmed:12117771 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-493835 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001165447.1|refseq:NP_060145.3|ensembl:ENSP00000424565|ensembl:ENSP00000261944|ensembl:ENSG00000074276(gene)|ensembl:ENST00000261944(transcript)|ensembl:ENST00000510636(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005903"(brush border)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060243"(negative regulation of cell growth involved in contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090675"(intermicrovillar adhesion)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR039808|rcsb pdb:5CZR|go:"GO:0031528"(microvillus membrane) refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site) - - - dataset:Cancer - Interactions investigated in the context of cancer taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/02/22 2014/10/16 rogid:hrWy8QtZUYFgmvMQ96IwOm+F3X09606 rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606 intact-crc:7AD30FB2F41750BC|rigid:XpUA4aWwpoWqkqJynxgNqOq4dYc false - binding-associated region:862-1798(IPR001478)|flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BYE9 uniprotkb:Q6P0Q8 intact:EBI-493793|uniprotkb:Q9NXP8|uniprotkb:A1L3U4|uniprotkb:A6NC80|intact:EBI-28985604|ensembl:ENSP00000261944|ensembl:ENSP00000424565 intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671 psi-mi:cdhr2_human(display_long)|uniprotkb:PCLKC(gene name synonym)|uniprotkb:Protocadherin LKC(gene name synonym)|uniprotkb:CDHR2(gene name)|psi-mi:CDHR2(display_short)|uniprotkb:PCDH24(gene name synonym)|uniprotkb:Protocadherin-24(gene name synonym) psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short) psi-mi:"MI:0428"(imaging technique) Okazaki et al. (2002) pubmed:12117771 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-493858 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001165447.1|refseq:NP_060145.3|ensembl:ENSP00000424565|ensembl:ENSP00000261944|ensembl:ENSG00000074276(gene)|ensembl:ENST00000261944(transcript)|ensembl:ENST00000510636(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005903"(brush border)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060243"(negative regulation of cell growth involved in contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090675"(intermicrovillar adhesion)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR039808|rcsb pdb:5CZR|go:"GO:0031528"(microvillus membrane) refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site) go:"GO:0019898"(extrinsic component of membrane) - - dataset:Cancer - Interactions investigated in the context of cancer taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2005/02/22 2014/10/16 rogid:hrWy8QtZUYFgmvMQ96IwOm+F3X09606 rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606 intact-crc:150618E6FC8FC431|rigid:XpUA4aWwpoWqkqJynxgNqOq4dYc false - ha tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)