#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q01860 uniprotkb:Q9UJU5 intact:EBI-475687|uniprotkb:P31359|uniprotkb:Q15167|uniprotkb:Q15168|uniprotkb:Q16422|uniprotkb:A6NCS1|uniprotkb:A6NLL8|uniprotkb:Q5STF3|uniprotkb:Q5STF4|ensembl:ENSP00000259915|ensembl:ENSP00000373016|ensembl:ENSP00000388842|ensembl:ENSP00000391681|ensembl:ENSP00000392877|ensembl:ENSP00000400047|ensembl:ENSP00000405041|uniprotkb:D2IYK4 intact:EBI-475674|uniprotkb:Q9BYM2|uniprotkb:Q9UDD1|ensembl:ENSP00000360157 psi-mi:po5f1_human(display_long)|uniprotkb:Octamer-binding transcription factor 3(gene name synonym)|uniprotkb:Octamer-binding protein 3(gene name synonym)|uniprotkb:POU5F1(gene name)|psi-mi:POU5F1(display_short)|uniprotkb:OCT3(gene name synonym)|uniprotkb:OCT4(gene name synonym)|uniprotkb:OTF3(gene name synonym)|uniprotkb:Octamer-binding protein 4(gene name synonym) psi-mi:foxd3_human(display_long)|uniprotkb:HFH2(gene name synonym)|uniprotkb:HNF3/FH transcription factor genesis(gene name synonym)|uniprotkb:FOXD3(gene name)|psi-mi:FOXD3(display_short) psi-mi:"MI:0096"(pull down) Guo et al. (2002) pubmed:11891324 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-475717 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001272916.1|refseq:NP_002692.2|ensembl:ENSG00000204531(gene)|ensembl:ENSG00000206454(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0003723"(RNA binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060795"(cell fate commitment involved in formation of primary germ layer)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0090081"(regulation of heart induction by regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090308"(regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR015585(POU domain class 5)|interpro:IPR017970|mint:Q01860|rcsb pdb:6T90|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-452723|ensembl:ENSG00000230336(gene)|ensembl:ENSG00000233911(gene)|ensembl:ENSG00000235068(gene)|ensembl:ENSG00000237582(gene)|ensembl:ENST00000259915(transcript)|ensembl:ENST00000383524(transcript)|ensembl:ENST00000429603(transcript)|ensembl:ENST00000433063(transcript)|ensembl:ENST00000434616(transcript)|ensembl:ENST00000437747(transcript)|ensembl:ENSG00000229094(gene)|ensembl:ENST00000454714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001824"(blastocyst development)|go:"GO:0003130"(BMP signaling pathway involved in heart induction)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|dip:DIP-33440N refseq:NP_036315.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|ensembl:ENST00000371116(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-2892247|ensembl:ENSG00000187140(gene) - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/01/14 2014/10/16 rogid:eMEp6g1n+kU2YnuRprn2B79q7OM9606 rogid:zKNoMjX9lFqo0HzMbrSc7W5a0Eg9606 intact-crc:43D1181056DE09DA|rigid:EU3Dd9X6sPDpw2pnDe8BJZrgjvk false - glutathione s tranferase tag:?-?|binding-associated region:141..141-235..235(IPR001766) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UJU5 uniprotkb:Q01860 intact:EBI-475674|uniprotkb:Q9BYM2|uniprotkb:Q9UDD1|ensembl:ENSP00000360157 intact:EBI-475687|uniprotkb:P31359|uniprotkb:Q15167|uniprotkb:Q15168|uniprotkb:Q16422|uniprotkb:A6NCS1|uniprotkb:A6NLL8|uniprotkb:Q5STF3|uniprotkb:Q5STF4|ensembl:ENSP00000259915|ensembl:ENSP00000373016|ensembl:ENSP00000388842|ensembl:ENSP00000391681|ensembl:ENSP00000392877|ensembl:ENSP00000400047|ensembl:ENSP00000405041|uniprotkb:D2IYK4 psi-mi:foxd3_human(display_long)|uniprotkb:HFH2(gene name synonym)|uniprotkb:HNF3/FH transcription factor genesis(gene name synonym)|uniprotkb:FOXD3(gene name)|psi-mi:FOXD3(display_short) psi-mi:po5f1_human(display_long)|uniprotkb:Octamer-binding transcription factor 3(gene name synonym)|uniprotkb:Octamer-binding protein 3(gene name synonym)|uniprotkb:POU5F1(gene name)|psi-mi:POU5F1(display_short)|uniprotkb:OCT3(gene name synonym)|uniprotkb:OCT4(gene name synonym)|uniprotkb:OTF3(gene name synonym)|uniprotkb:Octamer-binding protein 4(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Guo et al. (2002) pubmed:11891324 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-475728 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036315.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|ensembl:ENST00000371116(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-2892247|ensembl:ENSG00000187140(gene) refseq:NP_001272916.1|refseq:NP_002692.2|ensembl:ENSG00000204531(gene)|ensembl:ENSG00000206454(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0003723"(RNA binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060795"(cell fate commitment involved in formation of primary germ layer)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0090081"(regulation of heart induction by regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090308"(regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR015585(POU domain class 5)|interpro:IPR017970|mint:Q01860|rcsb pdb:6T90|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-452723|ensembl:ENSG00000230336(gene)|ensembl:ENSG00000233911(gene)|ensembl:ENSG00000235068(gene)|ensembl:ENSG00000237582(gene)|ensembl:ENST00000259915(transcript)|ensembl:ENST00000383524(transcript)|ensembl:ENST00000429603(transcript)|ensembl:ENST00000433063(transcript)|ensembl:ENST00000434616(transcript)|ensembl:ENST00000437747(transcript)|ensembl:ENSG00000229094(gene)|ensembl:ENST00000454714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001824"(blastocyst development)|go:"GO:0003130"(BMP signaling pathway involved in heart induction)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|dip:DIP-33440N - - - - taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/01/14 2014/10/16 rogid:zKNoMjX9lFqo0HzMbrSc7W5a0Eg9606 rogid:eMEp6g1n+kU2YnuRprn2B79q7OM9606 intact-crc:2E0467A315D88B47|rigid:EU3Dd9X6sPDpw2pnDe8BJZrgjvk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)