#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06790	uniprotkb:Q92831	intact:EBI-7010629|intact:MINT-95532	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	psi-mi:ve2_hpv18(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (2002)	pubmed:11744716|mint:MINT-5214946	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8065666|mint:MINT-68782	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0044191"(host cell mitochondrial membrane)|rcsb pdb:1F9F|rcsb pdb:1JJ4|rcsb pdb:1QQH|rcsb pdb:1TUE|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P06790|interpro:IPR042503|interpro:IPR042504|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|mint:MINT-608930(identity)	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N|mint:MINT-608937(identity)	-	function:"E2 regulates viral transcription and DNA replication. It binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication"|comment:mint|comment:homomint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/11/07	2014/10/16	rogid:XIwvFJvCt9Stcel0TFSU3GGlWV8333761	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	intact-crc:93BC2CCB451C24BA|rigid:eYxarVVwjCkJ6PwLnjFytF6Eyzs	false	glutathione s tranferase tag:?-?(MINT-608931)	flag tag:?-?(MINT-608938)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06790	uniprotkb:Q92831	intact:EBI-7010629|intact:MINT-95532	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	psi-mi:ve2_hpv18(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (2002)	pubmed:11744716|mint:MINT-5214946	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8065686|mint:MINT-68783	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0044191"(host cell mitochondrial membrane)|rcsb pdb:1F9F|rcsb pdb:1JJ4|rcsb pdb:1QQH|rcsb pdb:1TUE|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P06790|interpro:IPR042503|interpro:IPR042504|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|mint:MINT-608826(identity)	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N|mint:MINT-608835(identity)	-	function:"E2 regulates viral transcription and DNA replication. It binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication"|comment:mint|comment:homomint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/11/07	2014/10/16	rogid:XIwvFJvCt9Stcel0TFSU3GGlWV8333761	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	intact-crc:78C113268D86129C|rigid:eYxarVVwjCkJ6PwLnjFytF6Eyzs	false	binding-associated region:1-261(MINT-608827)|glutathione s tranferase tag:?-?(MINT-608829)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06790	uniprotkb:Q92831	intact:EBI-7010629|intact:MINT-95532	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	psi-mi:ve2_hpv18(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (2002)	pubmed:11744716|mint:MINT-5214946	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8065732|mint:MINT-68784	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0044191"(host cell mitochondrial membrane)|rcsb pdb:1F9F|rcsb pdb:1JJ4|rcsb pdb:1QQH|rcsb pdb:1TUE|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P06790|interpro:IPR042503|interpro:IPR042504|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|mint:MINT-608896(identity)	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N|mint:MINT-608905(identity)	-	function:"E2 regulates viral transcription and DNA replication. It binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication"|comment:mint|comment:homomint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:XIwvFJvCt9Stcel0TFSU3GGlWV8333761	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	intact-crc:01475EB360694572|rigid:eYxarVVwjCkJ6PwLnjFytF6Eyzs	false	binding-associated region:261-365(MINT-608897)|glutathione s tranferase tag:?-?(MINT-608899)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06790	uniprotkb:Q92831	intact:EBI-7010629|intact:MINT-95532	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	psi-mi:ve2_hpv18(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (2002)	pubmed:11744716|mint:MINT-5214946	taxid:333761(hpv18)|taxid:333761(Human papillomavirus type 18)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8065753|mint:MINT-68785	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0044191"(host cell mitochondrial membrane)|rcsb pdb:1F9F|rcsb pdb:1JJ4|rcsb pdb:1QQH|rcsb pdb:1TUE|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P06790|interpro:IPR042503|interpro:IPR042504|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|mint:MINT-608913(identity)	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N|mint:MINT-608918(identity)	-	function:"E2 regulates viral transcription and DNA replication. It binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication"|comment:mint|comment:homomint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:XIwvFJvCt9Stcel0TFSU3GGlWV8333761	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	intact-crc:552B2DDB7ADB6D68|rigid:eYxarVVwjCkJ6PwLnjFytF6Eyzs	false	-	glutathione s tranferase tag:?-?(MINT-608921)|binding-associated region:1-390(MINT-608919)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04015	uniprotkb:Q92831	intact:EBI-7010556|intact:MINT-95651	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	psi-mi:ve2_hpv11(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (2002)	pubmed:11744716|mint:MINT-5214946	taxid:10580(hpv11)|taxid:10580(Human papillomavirus type 11)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8065815|mint:MINT-68787	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:1R6K|rcsb pdb:1R6N|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P04015|interpro:IPR042503|interpro:IPR042504|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|mint:MINT-608862(identity)	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N|mint:MINT-608867(identity)	-	function:"E2 regulates viral transcription and DNA replication. It binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:HOBkNHD21+9IasbIqs8ViKVoyOE10580	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	intact-crc:534AA2497386B983|rigid:iFLp46WPIJURM7M00BxSEgJhliQ	false	-	binding-associated region:1-390(MINT-608868)|glutathione s tranferase tag:?-?(MINT-608870)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P03119	uniprotkb:Q92831	intact:EBI-8065774|intact:MINT-224985	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	psi-mi:ve2_hpv6b(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (2002)	pubmed:11744716|mint:MINT-5214946	taxid:10600(hpv6b)|taxid:10600(Human papillomavirus type 6b)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8065794|mint:MINT-68786	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR033668|interpro:IPR042503|interpro:IPR042504|refseq:NP_040299.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR035975|interpro:IPR036050|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|mint:MINT-608879(identity)	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N|mint:MINT-608884(identity)	-	function:"E2 regulates viral transcription and DNA replication. It binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:gCAc0k7BsQtmA1si1v2Q0ma339o10600	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	intact-crc:14B4EA3142875FB5|rigid:Bn4AWQsLn8z1h07U2FMWSNwcEs0	false	-	glutathione s tranferase tag:?-?(MINT-608887)|binding-associated region:1-390(MINT-608885)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92831	uniprotkb:P03120	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	intact:EBI-1779322|uniprotkb:Q71BI4	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:ve2_hpv16(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:"MI:0096"(pull down)	Lee et al. (2002)	pubmed:11744716|mint:MINT-5214946	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8065836|mint:MINT-68788	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N|mint:MINT-608850(identity)	refseq:NP_041328.1|dip:DIP-44574N|mint:P03120|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|interpro:IPR042503|interpro:IPR042504|rcsb pdb:1BY9|rcsb pdb:1DTO|rcsb pdb:1R8P|rcsb pdb:1ZZF|rcsb pdb:2NNU|rcsb pdb:2Q79|rcsb pdb:3MI7|mint:MINT-608845(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/07	2014/10/16	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	rogid:0/XZ8yUPpKVdUvpKjNxjHHQnmAE333760	intact-crc:A45F1DF88F44B364|rigid:eatsqD4xwv4ufYY7CwkNnbDczO8	false	binding-associated region:1-390(MINT-608851)|glutathione s tranferase tag:?-?(MINT-608853)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)