#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q7K105	uniprotkb:P08953	intact:EBI-129988|ensemblmetazoa:FBpp0087679|ensemblmetazoa:FBpp0305215|ensemblmetazoa:FBpp0311274	intact:EBI-143610|uniprotkb:A4V3G7|uniprotkb:A8WHK7|uniprotkb:Q8MRF3|uniprotkb:Q9VBB8|ensemblmetazoa:FBpp0084431|ensemblmetazoa:FBpp0303188	psi-mi:q7k105_drome(display_long)|uniprotkb:Myd88(gene name)|psi-mi:Myd88(display_short)|uniprotkb:DMMYD88(gene name synonym)|uniprotkb:DmMyD88(gene name synonym)|uniprotkb:DmMyd88(gene name synonym)|uniprotkb:Dmel\CG2078(gene name synonym)|uniprotkb:"EP(2)2535"(gene name synonym)|uniprotkb:Kra(gene name synonym)|uniprotkb:LD20892(gene name synonym)|uniprotkb:MYD88(gene name synonym)|uniprotkb:MyD88(gene name synonym)|uniprotkb:Myd88F(gene name synonym)|uniprotkb:dMYd88(gene name synonym)|uniprotkb:dMyD88(gene name synonym)|uniprotkb:dMyd88(gene name synonym)|uniprotkb:kra(gene name synonym)|uniprotkb:myd88(gene name synonym)|uniprotkb:CG2078(orf name)|uniprotkb:Dmel_CG2078(orf name)	psi-mi:toll_drome(display_long)|uniprotkb:Tl(gene name)|psi-mi:Tl(display_short)|uniprotkb:CG5490(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tauszig-Delamasure et al. (2002)	pubmed:11743586	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-524622	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_610479.1|flybase:FBgn0033402|refseq:NP_001286246.1|ensemblmetazoa:FBgn0033402(gene)|ensemblmetazoa:FBtr0088598(transcript)|ensemblmetazoa:FBtr0333000(transcript)|ensemblmetazoa:FBtr0345024(transcript)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005121"(Toll binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0070976"(TIR domain binding)|interpro:IPR011029(DEATH-like)|interpro:IPR017281(Myeloid differentiation primary response protein MyD88)|interpro:IPR035897|reactome:R-DME-1810476|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|reactome:R-DME-3134963|interpro:IPR000157(Toll-Interleukin receptor)|refseq:NP_001260821.1	refseq:NP_524518.1|refseq:NP_733166.1|flybase:FBgn0262473|dip:DIP-34358N|ensemblmetazoa:FBgn0262473(gene)|ensemblmetazoa:FBtr0085059(transcript)|ensemblmetazoa:FBtr0330155(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002229"(defense response to oomycetes)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007507"(heart development)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009597"(detection of virus)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0019955"(cytokine binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035208"(positive regulation of hemocyte proliferation)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046790"(virion binding)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0070976"(TIR domain binding)|go:"GO:1902875"(regulation of embryonic pattern specification)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR026906|interpro:IPR032675|interpro:IPR035897|rcsb pdb:4ARN|rcsb pdb:4ARR|rcsb pdb:4BV4|rcsb pdb:4LXR|rcsb pdb:4LXS|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874	-	-	-	-	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2005/03/31	2014/10/16	rogid:ylgI2zl+aLG3S8D2ER2DrTRUpI47227	rogid:6nIbDMNS71rQ+CzvUkspyPjTd707227	intact-crc:6DC137B9FCD7FE29|rigid:AKh/WPe9ypB1yl7O1uagx3xcllo	false	v5 tag:?-?|binding-associated region:224-371(IPR000157)	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q7K105	uniprotkb:Q05652	intact:EBI-129988|ensemblmetazoa:FBpp0087679|ensemblmetazoa:FBpp0305215|ensemblmetazoa:FBpp0311274	intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005	psi-mi:q7k105_drome(display_long)|uniprotkb:Myd88(gene name)|psi-mi:Myd88(display_short)|uniprotkb:DMMYD88(gene name synonym)|uniprotkb:DmMyD88(gene name synonym)|uniprotkb:DmMyd88(gene name synonym)|uniprotkb:Dmel\CG2078(gene name synonym)|uniprotkb:"EP(2)2535"(gene name synonym)|uniprotkb:Kra(gene name synonym)|uniprotkb:LD20892(gene name synonym)|uniprotkb:MYD88(gene name synonym)|uniprotkb:MyD88(gene name synonym)|uniprotkb:Myd88F(gene name synonym)|uniprotkb:dMYd88(gene name synonym)|uniprotkb:dMyD88(gene name synonym)|uniprotkb:dMyd88(gene name synonym)|uniprotkb:kra(gene name synonym)|uniprotkb:myd88(gene name synonym)|uniprotkb:CG2078(orf name)|uniprotkb:Dmel_CG2078(orf name)	psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tauszig-Delamasure et al. (2002)	pubmed:11743586	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-524632	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_610479.1|flybase:FBgn0033402|refseq:NP_001286246.1|ensemblmetazoa:FBgn0033402(gene)|ensemblmetazoa:FBtr0088598(transcript)|ensemblmetazoa:FBtr0333000(transcript)|ensemblmetazoa:FBtr0345024(transcript)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002347"(response to tumor cell)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005121"(Toll binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0070976"(TIR domain binding)|interpro:IPR011029(DEATH-like)|interpro:IPR017281(Myeloid differentiation primary response protein MyD88)|interpro:IPR035897|reactome:R-DME-1810476|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|reactome:R-DME-3134963|interpro:IPR000157(Toll-Interleukin receptor)|refseq:NP_001260821.1	refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N	-	-	-	-	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2005/03/31	2014/10/16	rogid:ylgI2zl+aLG3S8D2ER2DrTRUpI47227	rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227	intact-crc:CAAB7A3693C3197B|rigid:7/lPHF+puQZb7KaV3n/kU+iVMUE	false	v5 tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)