#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P30680	uniprotkb:Q9QX74	intact:EBI-7449065|intact:MINT-151186|ensembl:ENSRNOP00000003735	intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46	psi-mi:ssr2_rat(display_long)|uniprotkb:Sstr2(gene name)|psi-mi:Sstr2(display_short)|uniprotkb:SRIF-1(gene name synonym)	psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kreienkamp et al. (2000)	pubmed:11087996|mint:MINT-5213233	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7449101|mint:MINT-73125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3763|refseq:NP_062221.1|ensembl:ENSRNOG00000002793(gene)|ensembl:ENSRNOT00000003735(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030432"(peristalsis)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042594"(response to starvation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR002074(Somatostatin receptor, type 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P30680|rcsb pdb:6EXJ|reactome:R-RNO-375276|reactome:R-RNO-418594|mint:MINT-440674(identity)	rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1|mint:MINT-440681(identity)	-	comment:mint|function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3|comment:homomint|comment:mint	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/12/05	2014/10/16	rogid:FLVv30cGqYPd0U5WTkjzbCETEwE10116	rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116	intact-crc:10CDECBE1DBFFA1A|rigid:X5yzkVB5/OWqfusObufU+/XZMDY	false	t7 tag:?-?(MINT-440675)	tag:?-?(MINT-440682)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P30680	uniprotkb:Q9Y566	intact:EBI-7449065|intact:MINT-151186|ensembl:ENSRNOP00000003735	intact:EBI-3442234|uniprotkb:B7WNY6|uniprotkb:Q9NYW9|uniprotkb:A8MXP5|ensembl:ENSP00000293441	psi-mi:ssr2_rat(display_long)|uniprotkb:Sstr2(gene name)|psi-mi:Sstr2(display_short)|uniprotkb:SRIF-1(gene name synonym)	psi-mi:shan1_human(display_long)|uniprotkb:SHANK1(gene name)|psi-mi:SHANK1(display_short)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kreienkamp et al. (2000)	pubmed:11087996|mint:MINT-5213233	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7449165|mint:MINT-73126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3763|refseq:NP_062221.1|ensembl:ENSRNOG00000002793(gene)|ensembl:ENSRNOT00000003735(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030432"(peristalsis)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042594"(response to starvation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR002074(Somatostatin receptor, type 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P30680|rcsb pdb:6EXJ|reactome:R-RNO-375276|reactome:R-RNO-418594|mint:MINT-440571(identity)	refseq:XP_011525316.1|refseq:XP_006723296.1|refseq:NP_057232.2|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|ensembl:ENSG00000161681(gene)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|ensembl:ENST00000293441(transcript)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9Y566|rcsb pdb:6CPI|rcsb pdb:6YWZ|rcsb pdb:6YX0|rcsb pdb:6YX1|rcsb pdb:6YX2|reactome:R-HSA-6794361|ensembl:ENSP00000293441|ensembl:ENST00000359082|ensembl:ENSP00000351984|dip:DIP-40834N|mint:MINT-440578(identity)	-	comment:mint|function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3|comment:homomint|comment:mint	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/12/05	2014/10/16	rogid:FLVv30cGqYPd0U5WTkjzbCETEwE10116	rogid:XhX+mw+sujJRnA6RoKA1QeVywBY9606	intact-crc:862AC214F34E3BCB|rigid:63ULImMEbelk42TxGxy+8orUq74	false	t7 tag:?-?(MINT-440572)	tag:?-?(MINT-440581)|binding-associated region:1-1288(MINT-440579)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P30680	uniprotkb:Q92796	intact:EBI-7449065|intact:MINT-151186|ensembl:ENSRNOP00000003735	intact:EBI-80440|ensembl:ENSP00000363480|uniprotkb:Q9ULI8|uniprotkb:Q5JUW7|uniprotkb:D3DVU5|uniprotkb:B4E0H1|uniprotkb:Q5JUW6	psi-mi:ssr2_rat(display_long)|uniprotkb:Sstr2(gene name)|psi-mi:Sstr2(display_short)|uniprotkb:SRIF-1(gene name synonym)	psi-mi:dlg3_human(display_long)|uniprotkb:DLG3(gene name)|psi-mi:DLG3(display_short)|uniprotkb:KIAA1232(gene name synonym)|uniprotkb:Synapse-associated protein 102(gene name synonym)|uniprotkb:Neuroendocrine-DLG(gene name synonym)|uniprotkb:XLMR(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Kreienkamp et al. (2000)	pubmed:11087996|mint:MINT-5213233	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7449194|mint:MINT-73116	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3763|refseq:NP_062221.1|ensembl:ENSRNOG00000002793(gene)|ensembl:ENSRNOT00000003735(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030432"(peristalsis)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042594"(response to starvation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR002074(Somatostatin receptor, type 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P30680|rcsb pdb:6EXJ|reactome:R-RNO-375276|reactome:R-RNO-418594|mint:MINT-440613(identity)	ensembl:ENSG00000082458(gene)|ensembl:ENST00000374360(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019900"(kinase binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030426"(growth cone)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035763|interpro:IPR036028|interpro:IPR036034|rcsb pdb:1UM7|rcsb pdb:2FE5|rcsb pdb:2I1N|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-6794361|reactome:R-HSA-8849932|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|refseq:NP_001159750.1|refseq:NP_065781.1|refseq:NP_066943.2|refseq:XP_005262305.1|refseq:XP_016884815.1|mint:MINT-440623(identity)	-	comment:mint|function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:NFA|comment:homomint|comment:mint	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/12/05	2014/10/16	rogid:FLVv30cGqYPd0U5WTkjzbCETEwE10116	rogid:mnuw5iq2NexP1BL90IuQ1i21xo89606	intact-crc:0CAA15FC473A516E|rigid:WOqkYJ6xuKAZdQXiWwrQvl3Fu/c	false	tag:?-?(MINT-440617)|binding-associated region:316-369(MINT-440614)	tag:?-?(MINT-440624)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P30680	uniprotkb:Q9Y566	intact:EBI-7449065|intact:MINT-151186|ensembl:ENSRNOP00000003735	intact:EBI-3442234|uniprotkb:B7WNY6|uniprotkb:Q9NYW9|uniprotkb:A8MXP5|ensembl:ENSP00000293441	psi-mi:ssr2_rat(display_long)|uniprotkb:Sstr2(gene name)|psi-mi:Sstr2(display_short)|uniprotkb:SRIF-1(gene name synonym)	psi-mi:shan1_human(display_long)|uniprotkb:SHANK1(gene name)|psi-mi:SHANK1(display_short)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Kreienkamp et al. (2000)	pubmed:11087996|mint:MINT-5213233	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7449253|mint:MINT-73119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3763|refseq:NP_062221.1|ensembl:ENSRNOG00000002793(gene)|ensembl:ENSRNOT00000003735(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030432"(peristalsis)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042594"(response to starvation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR002074(Somatostatin receptor, type 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P30680|rcsb pdb:6EXJ|reactome:R-RNO-375276|reactome:R-RNO-418594|mint:MINT-440592(identity)	refseq:XP_011525316.1|refseq:XP_006723296.1|refseq:NP_057232.2|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|ensembl:ENSG00000161681(gene)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|ensembl:ENST00000293441(transcript)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9Y566|rcsb pdb:6CPI|rcsb pdb:6YWZ|rcsb pdb:6YX0|rcsb pdb:6YX1|rcsb pdb:6YX2|reactome:R-HSA-6794361|ensembl:ENSP00000293441|ensembl:ENST00000359082|ensembl:ENSP00000351984|dip:DIP-40834N|mint:MINT-440602(identity)	-	comment:mint|function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:NFA|comment:homomint|comment:mint	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/12/05	2014/10/16	rogid:FLVv30cGqYPd0U5WTkjzbCETEwE10116	rogid:XhX+mw+sujJRnA6RoKA1QeVywBY9606	intact-crc:6B16A02C2A9F6181|rigid:63ULImMEbelk42TxGxy+8orUq74	false	tag:?-?(MINT-440596)|binding-associated region:316-369(MINT-440593)	tag:?-?(MINT-440603)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P30680	uniprotkb:Q13424	intact:EBI-7449065|intact:MINT-151186|ensembl:ENSRNOP00000003735	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	psi-mi:ssr2_rat(display_long)|uniprotkb:Sstr2(gene name)|psi-mi:Sstr2(display_short)|uniprotkb:SRIF-1(gene name synonym)	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Kreienkamp et al. (2000)	pubmed:11087996|mint:MINT-5213233	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7449216|mint:MINT-73117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3763|refseq:NP_062221.1|ensembl:ENSRNOG00000002793(gene)|ensembl:ENSRNOT00000003735(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030432"(peristalsis)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042594"(response to starvation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR002074(Somatostatin receptor, type 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P30680|rcsb pdb:6EXJ|reactome:R-RNO-375276|reactome:R-RNO-418594|mint:MINT-440634(identity)	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N|mint:MINT-440644(identity)	-	comment:mint|function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:NFA|comment:homomint|comment:mint	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/12/05	2014/10/16	rogid:FLVv30cGqYPd0U5WTkjzbCETEwE10116	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	intact-crc:E2F8C3F54518A4BA|rigid:IfUtj6CQeQ02bUaZwjI2n7kn0gc	false	tag:?-?(MINT-440638)|binding-associated region:316-369(MINT-440635)	tag:?-?(MINT-440645)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P30680	uniprotkb:Q9QX74	intact:EBI-7449065|intact:MINT-151186|ensembl:ENSRNOP00000003735	intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46	psi-mi:ssr2_rat(display_long)|uniprotkb:Sstr2(gene name)|psi-mi:Sstr2(display_short)|uniprotkb:SRIF-1(gene name synonym)	psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)	psi-mi:"MI:0428"(imaging technique)	Kreienkamp et al. (2000)	pubmed:11087996|mint:MINT-5213233	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7449313|mint:MINT-73127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3763|refseq:NP_062221.1|ensembl:ENSRNOG00000002793(gene)|ensembl:ENSRNOT00000003735(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030432"(peristalsis)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042594"(response to starvation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR002074(Somatostatin receptor, type 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P30680|rcsb pdb:6EXJ|reactome:R-RNO-375276|reactome:R-RNO-418594|mint:MINT-440657(identity)	rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1|mint:MINT-440664(identity)	-	comment:mint|function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:homomint|comment:mint	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/12/05	2014/10/16	rogid:FLVv30cGqYPd0U5WTkjzbCETEwE10116	rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116	intact-crc:AE09BCE588797C77|rigid:X5yzkVB5/OWqfusObufU+/XZMDY	false	tag:?-?(MINT-440658)	tag:?-?(MINT-440665)	-	-	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:P30680	uniprotkb:Q9QX74	intact:EBI-7449065|intact:MINT-151186|ensembl:ENSRNOP00000003735	intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46	psi-mi:ssr2_rat(display_long)|uniprotkb:Sstr2(gene name)|psi-mi:Sstr2(display_short)|uniprotkb:SRIF-1(gene name synonym)	psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Kreienkamp et al. (2000)	pubmed:11087996|mint:MINT-5213233	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7449353|mint:MINT-73120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3763|refseq:NP_062221.1|ensembl:ENSRNOG00000002793(gene)|ensembl:ENSRNOT00000003735(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030432"(peristalsis)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042594"(response to starvation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR002074(Somatostatin receptor, type 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P30680|rcsb pdb:6EXJ|reactome:R-RNO-375276|reactome:R-RNO-418594|mint:MINT-440726(identity)	rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1|mint:MINT-440716(identity)	-	comment:mint|function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/05	2014/10/16	rogid:FLVv30cGqYPd0U5WTkjzbCETEwE10116	rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116	intact-crc:1C318C5E5C4172C7|rigid:X5yzkVB5/OWqfusObufU+/XZMDY	false	tag:?-?(MINT-440730)|binding-associated region:316-369(MINT-440727)	binding-associated region:248-339(MINT-440717)|glutathione s tranferase tag:?-?(MINT-440720)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P30680	uniprotkb:Q9Y566	intact:EBI-7449065|intact:MINT-151186|ensembl:ENSRNOP00000003735	intact:EBI-3442234|uniprotkb:B7WNY6|uniprotkb:Q9NYW9|uniprotkb:A8MXP5|ensembl:ENSP00000293441	psi-mi:ssr2_rat(display_long)|uniprotkb:Sstr2(gene name)|psi-mi:Sstr2(display_short)|uniprotkb:SRIF-1(gene name synonym)	psi-mi:shan1_human(display_long)|uniprotkb:SHANK1(gene name)|psi-mi:SHANK1(display_short)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Kreienkamp et al. (2000)	pubmed:11087996|mint:MINT-5213233	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7449402|mint:MINT-73124	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3763|refseq:NP_062221.1|ensembl:ENSRNOG00000002793(gene)|ensembl:ENSRNOT00000003735(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004994"(somatostatin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030432"(peristalsis)|go:"GO:0030900"(forebrain development)|go:"GO:0042277"(peptide binding)|go:"GO:0042594"(response to starvation)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000586(Somatostatin receptor)|interpro:IPR002074(Somatostatin receptor, type 2)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P30680|rcsb pdb:6EXJ|reactome:R-RNO-375276|reactome:R-RNO-418594|mint:MINT-440703(identity)	refseq:XP_011525316.1|refseq:XP_006723296.1|refseq:NP_057232.2|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|ensembl:ENSG00000161681(gene)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|ensembl:ENST00000293441(transcript)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9Y566|rcsb pdb:6CPI|rcsb pdb:6YWZ|rcsb pdb:6YX0|rcsb pdb:6YX1|rcsb pdb:6YX2|reactome:R-HSA-6794361|ensembl:ENSP00000293441|ensembl:ENST00000359082|ensembl:ENSP00000351984|dip:DIP-40834N|mint:MINT-440693(identity)	-	comment:mint|function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/12/05	2014/10/16	rogid:FLVv30cGqYPd0U5WTkjzbCETEwE10116	rogid:XhX+mw+sujJRnA6RoKA1QeVywBY9606	intact-crc:44439D207FE14C35|rigid:63ULImMEbelk42TxGxy+8orUq74	false	tag:?-?(MINT-440707)|binding-associated region:316-369(MINT-440704)	binding-associated region:663-754(MINT-440694)|glutathione s tranferase tag:?-?(MINT-440697)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)