#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P63280 uniprotkb:P25446 intact:EBI-80180|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q6RUT3|uniprotkb:Q86VB3|ensembl:ENSMUSP00000055714|ensembl:ENSMUSP00000134169|ensembl:ENSMUSP00000134261|ensembl:ENSMUSP00000134350|ensembl:ENSMUSP00000134450|ensembl:ENSMUSP00000134491 intact:EBI-296206|uniprotkb:Q9DCQ1|uniprotkb:Q6GT31|ensembl:ENSMUSP00000025691 psi-mi:ubc9_mouse(display_long)|uniprotkb:Ube2i(gene name)|psi-mi:Ube2i(display_short)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:Ubce9(gene name synonym)|uniprotkb:Ubce2i(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym) psi-mi:tnr6_mouse(display_long)|uniprotkb:Fas(gene name)|psi-mi:Fas(display_short)|uniprotkb:Apt1(gene name synonym)|uniprotkb:Tnfrsf6(gene name synonym)|uniprotkb:FASLG receptor(gene name synonym)|uniprotkb:Apoptosis-mediating surface antigen FAS(gene name synonym)|uniprotkb:Apo-1 antigen(gene name synonym) psi-mi:"MI:0018"(two hybrid) Rochat-Steiner et al. (2000) pubmed:11034606 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-524346 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171080.1|refseq:NP_001171081.1|refseq:NP_035795.1|ensembl:ENSMUSG00000015120(gene)|ensembl:ENSMUST00000049911(transcript)|ensembl:ENSMUST00000172618(transcript)|ensembl:ENSMUST00000173084(transcript)|ensembl:ENSMUST00000173713(transcript)|ensembl:ENSMUST00000174001(transcript)|ensembl:ENSMUST00000174031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990234"(transferase complex)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63280|rcsb pdb:1U9A|rcsb pdb:1U9B|rcsb pdb:2UYZ|rcsb pdb:2VRR|reactome:R-MMU-196791|reactome:R-MMU-3065678|reactome:R-MMU-3108214|reactome:R-MMU-3108232|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4085377|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-4655427|reactome:R-MMU-4755510|reactome:R-MMU-5693565|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-8866904|reactome:R-MMU-9615933|refseq:XP_006524111.1|refseq:XP_006524112.1|dip:DIP-29276N go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|ensembl:ENSMUSG00000024778(gene)|ensembl:ENSMUST00000025691(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0005516"(calmodulin binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019900"(kinase binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034198"(cellular response to amino acid starvation)|refseq:NP_032013.2|go:"GO:0048536"(spleen development)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070227"(lymphocyte apoptotic process)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097440"(apical dendrite)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR008063(Fas receptor)|interpro:IPR011029(DEATH-like)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR033998|interpro:IPR033999|mint:P25446|rcsb pdb:2NA6|rcsb pdb:3OQ9|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|dip:DIP-31093N - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/03/30 2014/10/16 rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo10090 rogid:ihK7Oxh+f0U7iYAsR2TlwLX3Ep410090 intact-crc:F3503BA9EB169007|rigid:Jt2GG/FF2vO/RMofPdW/e81SFeA false - binding-associated region:183-306 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25446 uniprotkb:Q9ERH7 intact:EBI-296206|uniprotkb:Q9DCQ1|uniprotkb:Q6GT31|ensembl:ENSMUSP00000025691 intact:EBI-524356|uniprotkb:A2AQH2|uniprotkb:O88906|uniprotkb:Q9QZR2|ensembl:ENSMUSP00000028600|ensembl:ENSMUSP00000106753 psi-mi:tnr6_mouse(display_long)|uniprotkb:Fas(gene name)|psi-mi:Fas(display_short)|uniprotkb:Apt1(gene name synonym)|uniprotkb:Tnfrsf6(gene name synonym)|uniprotkb:FASLG receptor(gene name synonym)|uniprotkb:Apoptosis-mediating surface antigen FAS(gene name synonym)|uniprotkb:Apo-1 antigen(gene name synonym) psi-mi:hipk3_mouse(display_long)|uniprotkb:Fas-interacting serine/threonine-protein kinase(gene name synonym)|uniprotkb:Nuclear body-associated kinase 3(gene name synonym)|uniprotkb:Androgen receptor-interacting nuclear protein kinase(gene name synonym)|uniprotkb:Hipk3(gene name)|psi-mi:Hipk3(display_short)|uniprotkb:Fist3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Rochat-Steiner et al. (2000) pubmed:11034606 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-524369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|ensembl:ENSMUSG00000024778(gene)|ensembl:ENSMUST00000025691(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0005516"(calmodulin binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019900"(kinase binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034198"(cellular response to amino acid starvation)|refseq:NP_032013.2|go:"GO:0048536"(spleen development)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070227"(lymphocyte apoptotic process)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097440"(apical dendrite)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR008063(Fas receptor)|interpro:IPR011029(DEATH-like)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR033998|interpro:IPR033999|mint:P25446|rcsb pdb:2NA6|rcsb pdb:3OQ9|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|dip:DIP-31093N go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0005886"(plasma membrane)|ensembl:ENSMUSG00000027177(gene)|ensembl:ENSMUST00000028600(transcript)|ensembl:ENSMUST00000111124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_034564.2 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/03/30 2014/10/16 rogid:ihK7Oxh+f0U7iYAsR2TlwLX3Ep410090 rogid:5shb3NxkkPKWUlfKtvTLm970p1I10090 intact-crc:4115EF47E5BDE296|rigid:gJK7dDVM+Iy+5jKBCrbS7AosKog false binding-associated region:183-306 binding-associated region:775-868 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ERH7 uniprotkb:P25446 intact:EBI-524356|uniprotkb:A2AQH2|uniprotkb:O88906|uniprotkb:Q9QZR2|ensembl:ENSMUSP00000028600|ensembl:ENSMUSP00000106753 intact:EBI-296206|uniprotkb:Q9DCQ1|uniprotkb:Q6GT31|ensembl:ENSMUSP00000025691 psi-mi:hipk3_mouse(display_long)|uniprotkb:Fas-interacting serine/threonine-protein kinase(gene name synonym)|uniprotkb:Nuclear body-associated kinase 3(gene name synonym)|uniprotkb:Androgen receptor-interacting nuclear protein kinase(gene name synonym)|uniprotkb:Hipk3(gene name)|psi-mi:Hipk3(display_short)|uniprotkb:Fist3(gene name synonym) psi-mi:tnr6_mouse(display_long)|uniprotkb:Fas(gene name)|psi-mi:Fas(display_short)|uniprotkb:Apt1(gene name synonym)|uniprotkb:Tnfrsf6(gene name synonym)|uniprotkb:FASLG receptor(gene name synonym)|uniprotkb:Apoptosis-mediating surface antigen FAS(gene name synonym)|uniprotkb:Apo-1 antigen(gene name synonym) psi-mi:"MI:0018"(two hybrid) Rochat-Steiner et al. (2000) pubmed:11034606 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-524398 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0005886"(plasma membrane)|ensembl:ENSMUSG00000027177(gene)|ensembl:ENSMUST00000028600(transcript)|ensembl:ENSMUST00000111124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_034564.2 go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|ensembl:ENSMUSG00000024778(gene)|ensembl:ENSMUST00000025691(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0005516"(calmodulin binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019900"(kinase binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034198"(cellular response to amino acid starvation)|refseq:NP_032013.2|go:"GO:0048536"(spleen development)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070227"(lymphocyte apoptotic process)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097440"(apical dendrite)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR008063(Fas receptor)|interpro:IPR011029(DEATH-like)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR033998|interpro:IPR033999|mint:P25446|rcsb pdb:2NA6|rcsb pdb:3OQ9|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|dip:DIP-31093N - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/03/30 2014/10/16 rogid:5shb3NxkkPKWUlfKtvTLm970p1I10090 rogid:ihK7Oxh+f0U7iYAsR2TlwLX3Ep410090 intact-crc:30720F0A56AF04F5|rigid:gJK7dDVM+Iy+5jKBCrbS7AosKog false - binding-associated region:221-288 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25446 uniprotkb:Q9ERH7 intact:EBI-296206|uniprotkb:Q9DCQ1|uniprotkb:Q6GT31|ensembl:ENSMUSP00000025691 intact:EBI-524356|uniprotkb:A2AQH2|uniprotkb:O88906|uniprotkb:Q9QZR2|ensembl:ENSMUSP00000028600|ensembl:ENSMUSP00000106753 psi-mi:tnr6_mouse(display_long)|uniprotkb:Fas(gene name)|psi-mi:Fas(display_short)|uniprotkb:Apt1(gene name synonym)|uniprotkb:Tnfrsf6(gene name synonym)|uniprotkb:FASLG receptor(gene name synonym)|uniprotkb:Apoptosis-mediating surface antigen FAS(gene name synonym)|uniprotkb:Apo-1 antigen(gene name synonym) psi-mi:hipk3_mouse(display_long)|uniprotkb:Fas-interacting serine/threonine-protein kinase(gene name synonym)|uniprotkb:Nuclear body-associated kinase 3(gene name synonym)|uniprotkb:Androgen receptor-interacting nuclear protein kinase(gene name synonym)|uniprotkb:Hipk3(gene name)|psi-mi:Hipk3(display_short)|uniprotkb:Fist3(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Rochat-Steiner et al. (2000) pubmed:11034606 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-524406 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|ensembl:ENSMUSG00000024778(gene)|ensembl:ENSMUST00000025691(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0005516"(calmodulin binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019900"(kinase binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034198"(cellular response to amino acid starvation)|refseq:NP_032013.2|go:"GO:0048536"(spleen development)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070227"(lymphocyte apoptotic process)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097440"(apical dendrite)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR008063(Fas receptor)|interpro:IPR011029(DEATH-like)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR033998|interpro:IPR033999|mint:P25446|rcsb pdb:2NA6|rcsb pdb:3OQ9|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|dip:DIP-31093N go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0005886"(plasma membrane)|ensembl:ENSMUSG00000027177(gene)|ensembl:ENSMUST00000028600(transcript)|ensembl:ENSMUST00000111124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_034564.2 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2005/03/30 2014/10/16 rogid:ihK7Oxh+f0U7iYAsR2TlwLX3Ep410090 rogid:5shb3NxkkPKWUlfKtvTLm970p1I10090 intact-crc:D8733EAC6DE6D57E|rigid:gJK7dDVM+Iy+5jKBCrbS7AosKog false - binding-associated region:592-1192|flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ERH7 uniprotkb:Q61160 intact:EBI-524356|uniprotkb:A2AQH2|uniprotkb:O88906|uniprotkb:Q9QZR2|ensembl:ENSMUSP00000028600|ensembl:ENSMUSP00000106753 intact:EBI-524415|uniprotkb:Q3TC37|uniprotkb:Q61082|ensembl:ENSMUSP00000033394 psi-mi:hipk3_mouse(display_long)|uniprotkb:Fas-interacting serine/threonine-protein kinase(gene name synonym)|uniprotkb:Nuclear body-associated kinase 3(gene name synonym)|uniprotkb:Androgen receptor-interacting nuclear protein kinase(gene name synonym)|uniprotkb:Hipk3(gene name)|psi-mi:Hipk3(display_short)|uniprotkb:Fist3(gene name synonym) psi-mi:fadd_mouse(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:Fadd(gene name)|psi-mi:Fadd(display_short)|uniprotkb:Mort1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Rochat-Steiner et al. (2000) pubmed:11034606 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-524430 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0005886"(plasma membrane)|ensembl:ENSMUSG00000027177(gene)|ensembl:ENSMUST00000028600(transcript)|ensembl:ENSMUST00000111124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_034564.2 ensembl:ENSMUSG00000031077(gene)|ensembl:ENSMUST00000033394(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002020"(protease binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0035877"(death effector domain binding)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0044297"(cell body)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0089720"(caspase binding)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097342"(ripoptosome)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:2000454"(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|mint:Q61160|rcsb pdb:1FAD|reactome:R-MMU-140534|reactome:R-MMU-2562578|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5675482|reactome:R-MMU-69416|reactome:R-MMU-75157|reactome:R-MMU-75158|refseq:NP_034305.1|dip:DIP-34771N - - - kinetics:"The interaction between FIST and FADD was reduced if Fas (tumor necrosis factor receptor superfamily member 6 precursor protein) was not present."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2005/03/30 2014/10/16 rogid:5shb3NxkkPKWUlfKtvTLm970p1I10090 rogid:0pzBrb1MrPRQ1IL9cdXg57tneNE10090 intact-crc:BC5F98A3979EC877|rigid:eF2vUo1epPa5WbocI4rnPrdR1Gc false flag tag:n-n phosphorylated residue:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O35613 uniprotkb:Q9ERH7 intact:EBI-77304|uniprotkb:Q9QWT8|uniprotkb:Q9QWV3 intact:EBI-524356|uniprotkb:A2AQH2|uniprotkb:O88906|uniprotkb:Q9QZR2|ensembl:ENSMUSP00000028600|ensembl:ENSMUSP00000106753 psi-mi:daxx_mouse(display_long)|uniprotkb:Daxx(gene name)|psi-mi:Daxx(display_short)|uniprotkb:Daxx(gene name synonym) psi-mi:hipk3_mouse(display_long)|uniprotkb:Fas-interacting serine/threonine-protein kinase(gene name synonym)|uniprotkb:Nuclear body-associated kinase 3(gene name synonym)|uniprotkb:Androgen receptor-interacting nuclear protein kinase(gene name synonym)|uniprotkb:Hipk3(gene name)|psi-mi:Hipk3(display_short)|uniprotkb:Fist3(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Rochat-Steiner et al. (2000) pubmed:11034606 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-524451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186662.1|refseq:NP_031855.3|refseq:XP_006523644.1|refseq:XP_006523645.1|mint:O35613|dip:DIP-30972N|refseq:XP_006523643.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0001741"(XY body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030578"(PML body organization)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|reactome:R-MMU-3899300|reactome:R-MMU-6804757|reactome:R-MMU-9670095 go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0005886"(plasma membrane)|ensembl:ENSMUSG00000027177(gene)|ensembl:ENSMUST00000028600(transcript)|ensembl:ENSMUST00000111124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_034564.2 - - - kinetics:"FIST protein which had a truncated kinase domain (142- 433) displayed reduced binding affinity for Daxx in this study."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2005/03/30 2014/10/16 rogid:/tlUn6VH6raf1J1r07iaYyKarek10090 rogid:5shb3NxkkPKWUlfKtvTLm970p1I10090 intact-crc:7E0CF261302AA598|rigid:VQCHiYJt/mxwCbatPe7xpZEDRzU false - flag tag:n-n|binding-associated region:1-433 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)