#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P31016 uniprotkb:Q00959 intact:EBI-375655|uniprotkb:P97631|ensembl:ENSRNOP00000059045 intact:EBI-630970|uniprotkb:O08948|uniprotkb:Q63728 psi-mi:dlg4_rat(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)|uniprotkb:Psd95(gene name synonym) psi-mi:nmde1_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Bassand et al. (1999) pubmed:10336672|mint:MINT-5211482|doi:10.1046/j.1460-9568.1999.00611 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7000637|mint:MINT-72564 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|rcsb pdb:1TP3|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:P31016|rcsb pdb:1BE9|rcsb pdb:1BFE|rcsb pdb:1IU0|rcsb pdb:1IU2|rcsb pdb:1JXM|rcsb pdb:1JXO|rcsb pdb:1KJW|rcsb pdb:1QLC|rcsb pdb:1RGR|rcsb pdb:5MZ7|rcsb pdb:5W72|rcsb pdb:5YPO|rcsb pdb:5YPR|rcsb pdb:7CQF|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5625900|reactome:R-RNO-5673001|reactome:R-RNO-5682910|reactome:R-RNO-6794361|reactome:R-RNO-8849932|rcsb pdb:1TP5|rcsb pdb:1TQ3|rcsb pdb:2KA9|rcsb pdb:2MHO|rcsb pdb:2XKX|rcsb pdb:3GSL|rcsb pdb:3WP0|rcsb pdb:3WP1|rcsb pdb:5B64|rcsb pdb:5D13|rcsb pdb:5GNV|rcsb pdb:5HDY|rcsb pdb:5HEB|rcsb pdb:5HED|rcsb pdb:5HET|rcsb pdb:5HEY|rcsb pdb:5HF1|rcsb pdb:5HF4|rcsb pdb:5HFB|rcsb pdb:5HFC|rcsb pdb:5HFD|rcsb pdb:5HFE|rcsb pdb:5HFF|ensembl:ENSRNOG00000018526(gene)|ensembl:ENSRNOT00000068493(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|rgd:68424|refseq:NP_062567.1|dip:DIP-29264N|mint:MINT-368114(identity) rgd:2737|refseq:NP_036705.3|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009611"(response to wounding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0019901"(protein kinase binding)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2A5S|rcsb pdb:2A5T|rcsb pdb:4JWX|rcsb pdb:4NF4|rcsb pdb:4NF5|rcsb pdb:4NF6|rcsb pdb:4NF8|rcsb pdb:5DEX|rcsb pdb:5I56|rcsb pdb:5I57|rcsb pdb:5I58|rcsb pdb:5I59|rcsb pdb:5JTY|rcsb pdb:5TPW|rcsb pdb:5TQ0|rcsb pdb:5TQ2|rcsb pdb:5U8C|rcsb pdb:5VIH|rcsb pdb:5VII|rcsb pdb:5VIJ|rcsb pdb:6MM9|rcsb pdb:6MMA|rcsb pdb:6MMB|rcsb pdb:6MMG|rcsb pdb:6MMH|rcsb pdb:6MMI|rcsb pdb:6MMJ|rcsb pdb:6MMK|rcsb pdb:6MML|rcsb pdb:6MMM|rcsb pdb:6MMN|rcsb pdb:6MMP|rcsb pdb:6MMR|rcsb pdb:6MMS|rcsb pdb:6MMT|rcsb pdb:6MMU|rcsb pdb:6MMV|rcsb pdb:6MMW|rcsb pdb:6MMX|rcsb pdb:6ODL|rcsb pdb:6OVD|rcsb pdb:6OVE|rcsb pdb:6USU|rcsb pdb:6USV|rcsb pdb:6UZ6|rcsb pdb:6UZG|rcsb pdb:6UZR|rcsb pdb:6UZW|rcsb pdb:6UZX|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051707"(response to other organism)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|dip:DIP-34031N|reactome:R-RNO-438066|reactome:R-RNO-8849932|reactome:R-RNO-9609736|mint:MINT-368104(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1 F3B F4A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:4oWbxT/HVvWQqdbFqt3htRuQNpw10116 rogid:zYnLjzOSp/wEOjcHJum+QAoQxDI10116 intact-crc:EA5366C4E659B359|rigid:dmhfhXVAi26TXT2DpSrFYHwH9HI false binding-associated region:21-467(MINT-368115)|tag:?-?(MINT-368118) binding-associated region:1093-1464(MINT-368105)|tag:?-?(MINT-368108) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q00959 uniprotkb:P31016 intact:EBI-630970|uniprotkb:O08948|uniprotkb:Q63728 intact:EBI-375655|uniprotkb:P97631|ensembl:ENSRNOP00000059045 psi-mi:nmde1_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym) psi-mi:dlg4_rat(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)|uniprotkb:Psd95(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Bassand et al. (1999) pubmed:10336672|mint:MINT-5211482|doi:10.1046/j.1460-9568.1999.00611 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7000663|mint:MINT-72565 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2737|refseq:NP_036705.3|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009611"(response to wounding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0019901"(protein kinase binding)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2A5S|rcsb pdb:2A5T|rcsb pdb:4JWX|rcsb pdb:4NF4|rcsb pdb:4NF5|rcsb pdb:4NF6|rcsb pdb:4NF8|rcsb pdb:5DEX|rcsb pdb:5I56|rcsb pdb:5I57|rcsb pdb:5I58|rcsb pdb:5I59|rcsb pdb:5JTY|rcsb pdb:5TPW|rcsb pdb:5TQ0|rcsb pdb:5TQ2|rcsb pdb:5U8C|rcsb pdb:5VIH|rcsb pdb:5VII|rcsb pdb:5VIJ|rcsb pdb:6MM9|rcsb pdb:6MMA|rcsb pdb:6MMB|rcsb pdb:6MMG|rcsb pdb:6MMH|rcsb pdb:6MMI|rcsb pdb:6MMJ|rcsb pdb:6MMK|rcsb pdb:6MML|rcsb pdb:6MMM|rcsb pdb:6MMN|rcsb pdb:6MMP|rcsb pdb:6MMR|rcsb pdb:6MMS|rcsb pdb:6MMT|rcsb pdb:6MMU|rcsb pdb:6MMV|rcsb pdb:6MMW|rcsb pdb:6MMX|rcsb pdb:6ODL|rcsb pdb:6OVD|rcsb pdb:6OVE|rcsb pdb:6USU|rcsb pdb:6USV|rcsb pdb:6UZ6|rcsb pdb:6UZG|rcsb pdb:6UZR|rcsb pdb:6UZW|rcsb pdb:6UZX|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051707"(response to other organism)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|dip:DIP-34031N|reactome:R-RNO-438066|reactome:R-RNO-8849932|reactome:R-RNO-9609736|mint:MINT-368081(identity) go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|rcsb pdb:1TP3|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:P31016|rcsb pdb:1BE9|rcsb pdb:1BFE|rcsb pdb:1IU0|rcsb pdb:1IU2|rcsb pdb:1JXM|rcsb pdb:1JXO|rcsb pdb:1KJW|rcsb pdb:1QLC|rcsb pdb:1RGR|rcsb pdb:5MZ7|rcsb pdb:5W72|rcsb pdb:5YPO|rcsb pdb:5YPR|rcsb pdb:7CQF|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5625900|reactome:R-RNO-5673001|reactome:R-RNO-5682910|reactome:R-RNO-6794361|reactome:R-RNO-8849932|rcsb pdb:1TP5|rcsb pdb:1TQ3|rcsb pdb:2KA9|rcsb pdb:2MHO|rcsb pdb:2XKX|rcsb pdb:3GSL|rcsb pdb:3WP0|rcsb pdb:3WP1|rcsb pdb:5B64|rcsb pdb:5D13|rcsb pdb:5GNV|rcsb pdb:5HDY|rcsb pdb:5HEB|rcsb pdb:5HED|rcsb pdb:5HET|rcsb pdb:5HEY|rcsb pdb:5HF1|rcsb pdb:5HF4|rcsb pdb:5HFB|rcsb pdb:5HFC|rcsb pdb:5HFD|rcsb pdb:5HFE|rcsb pdb:5HFF|ensembl:ENSRNOG00000018526(gene)|ensembl:ENSRNOT00000068493(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|rgd:68424|refseq:NP_062567.1|dip:DIP-29264N|mint:MINT-368091(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1 F3D F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:zYnLjzOSp/wEOjcHJum+QAoQxDI10116 rogid:4oWbxT/HVvWQqdbFqt3htRuQNpw10116 intact-crc:327E2A33E6B302F8|rigid:dmhfhXVAi26TXT2DpSrFYHwH9HI false tag:?-?(MINT-368085)|binding-associated region:1093-1464(MINT-368082) tag:?-?(MINT-368095)|binding-associated region:21-467(MINT-368092) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q00959 uniprotkb:Q62696 intact:EBI-630970|uniprotkb:O08948|uniprotkb:Q63728 intact:EBI-389325 psi-mi:nmde1_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym) psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Bassand et al. (1999) pubmed:10336672|mint:MINT-5211482|doi:10.1046/j.1460-9568.1999.00611 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7000689|mint:MINT-72566 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2737|refseq:NP_036705.3|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009611"(response to wounding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0019901"(protein kinase binding)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2A5S|rcsb pdb:2A5T|rcsb pdb:4JWX|rcsb pdb:4NF4|rcsb pdb:4NF5|rcsb pdb:4NF6|rcsb pdb:4NF8|rcsb pdb:5DEX|rcsb pdb:5I56|rcsb pdb:5I57|rcsb pdb:5I58|rcsb pdb:5I59|rcsb pdb:5JTY|rcsb pdb:5TPW|rcsb pdb:5TQ0|rcsb pdb:5TQ2|rcsb pdb:5U8C|rcsb pdb:5VIH|rcsb pdb:5VII|rcsb pdb:5VIJ|rcsb pdb:6MM9|rcsb pdb:6MMA|rcsb pdb:6MMB|rcsb pdb:6MMG|rcsb pdb:6MMH|rcsb pdb:6MMI|rcsb pdb:6MMJ|rcsb pdb:6MMK|rcsb pdb:6MML|rcsb pdb:6MMM|rcsb pdb:6MMN|rcsb pdb:6MMP|rcsb pdb:6MMR|rcsb pdb:6MMS|rcsb pdb:6MMT|rcsb pdb:6MMU|rcsb pdb:6MMV|rcsb pdb:6MMW|rcsb pdb:6MMX|rcsb pdb:6ODL|rcsb pdb:6OVD|rcsb pdb:6OVE|rcsb pdb:6USU|rcsb pdb:6USV|rcsb pdb:6UZ6|rcsb pdb:6UZG|rcsb pdb:6UZR|rcsb pdb:6UZW|rcsb pdb:6UZX|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051707"(response to other organism)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|dip:DIP-34031N|reactome:R-RNO-438066|reactome:R-RNO-8849932|reactome:R-RNO-9609736|mint:MINT-368029(identity) rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N|mint:MINT-368042(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1 F5B F6A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:zYnLjzOSp/wEOjcHJum+QAoQxDI10116 rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116 intact-crc:BCC25E1A69027AF1|rigid:rXrcPWsaRZE8dEYyQUDcVJNa8mo false mutation decreasing interaction:1463-1463,1462-1462(MINT-368033)|tag:?-?(MINT-368036)|binding-associated region:1093-1464(MINT-368030) binding-associated region:140-680(MINT-368043)|tag:?-?(MINT-368046) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q00959 uniprotkb:Q62696 intact:EBI-630970|uniprotkb:O08948|uniprotkb:Q63728 intact:EBI-389325 psi-mi:nmde1_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym) psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Bassand et al. (1999) pubmed:10336672|mint:MINT-5211482|doi:10.1046/j.1460-9568.1999.00611 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7000737|mint:MINT-72567 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2737|refseq:NP_036705.3|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009611"(response to wounding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0019901"(protein kinase binding)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2A5S|rcsb pdb:2A5T|rcsb pdb:4JWX|rcsb pdb:4NF4|rcsb pdb:4NF5|rcsb pdb:4NF6|rcsb pdb:4NF8|rcsb pdb:5DEX|rcsb pdb:5I56|rcsb pdb:5I57|rcsb pdb:5I58|rcsb pdb:5I59|rcsb pdb:5JTY|rcsb pdb:5TPW|rcsb pdb:5TQ0|rcsb pdb:5TQ2|rcsb pdb:5U8C|rcsb pdb:5VIH|rcsb pdb:5VII|rcsb pdb:5VIJ|rcsb pdb:6MM9|rcsb pdb:6MMA|rcsb pdb:6MMB|rcsb pdb:6MMG|rcsb pdb:6MMH|rcsb pdb:6MMI|rcsb pdb:6MMJ|rcsb pdb:6MMK|rcsb pdb:6MML|rcsb pdb:6MMM|rcsb pdb:6MMN|rcsb pdb:6MMP|rcsb pdb:6MMR|rcsb pdb:6MMS|rcsb pdb:6MMT|rcsb pdb:6MMU|rcsb pdb:6MMV|rcsb pdb:6MMW|rcsb pdb:6MMX|rcsb pdb:6ODL|rcsb pdb:6OVD|rcsb pdb:6OVE|rcsb pdb:6USU|rcsb pdb:6USV|rcsb pdb:6UZ6|rcsb pdb:6UZG|rcsb pdb:6UZR|rcsb pdb:6UZW|rcsb pdb:6UZX|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051707"(response to other organism)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|dip:DIP-34031N|reactome:R-RNO-438066|reactome:R-RNO-8849932|reactome:R-RNO-9609736|mint:MINT-368055(identity) rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N|mint:MINT-368068(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1 F5D F6B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/11/22 2014/10/16 rogid:zYnLjzOSp/wEOjcHJum+QAoQxDI10116 rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116 intact-crc:D7A5D5D23898E3A1|rigid:rXrcPWsaRZE8dEYyQUDcVJNa8mo false binding-associated region:1093-1464(MINT-368056)|mutation decreasing interaction:1462-1462,1463-1463(MINT-368059)|tag:?-?(MINT-368062) tag:?-?(MINT-368072)|binding-associated region:140-680(MINT-368069) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)