#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P62577 uniprotkb:P29477 intact:EBI-8626104|uniprotkb:P00483|intact:MINT-1528209 intact:EBI-298897|ensembl:ENSMUSP00000018610|uniprotkb:O70515|uniprotkb:O70516|uniprotkb:Q5SXT3|uniprotkb:Q6P6A0|uniprotkb:Q8R410 psi-mi:cat_ecolx(display_long)|uniprotkb:cat(gene name)|psi-mi:cat(display_short) psi-mi:nos2_mouse(display_long)|uniprotkb:Nos2(gene name)|psi-mi:Nos2(display_short)|uniprotkb:Inosl(gene name synonym)|uniprotkb:Inducible NO synthase(gene name synonym)|uniprotkb:NOS type II(gene name synonym)|uniprotkb:Macrophage NOS(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase NOS2(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Crane et al. (1997) pubmed:9334294|mint:MINT-5221688 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8626124|mint:MINT-25062 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009068571.1|refseq:YP_009071093.1|refseq:YP_009071408.1|go:"GO:0008811"(chloramphenicol O-acetyltransferase activity)|go:"GO:0046677"(response to antibiotic)|refseq:YP_001816591.1|rcsb pdb:1NOC|rcsb pdb:1Q23|refseq:YP_025721.1|interpro:IPR018372|rcsb pdb:3U9B|rcsb pdb:1PD5|refseq:YP_001096419.1|rcsb pdb:3U9F|refseq:WP_000412211.1|refseq:YP_008995272.1|refseq:YP_008997430.1|interpro:IPR023213|interpro:IPR001707(Chloramphenicol acetyltransferase)|mint:MINT-1528225(identity) interpro:IPR023173|interpro:IPR029039|interpro:IPR036119|interpro:IPR039261|rcsb pdb:1DD7|rcsb pdb:1DF1|rcsb pdb:1DWV|rcsb pdb:1DWW|rcsb pdb:1DWX|rcsb pdb:1JWJ|rcsb pdb:1JWK|rcsb pdb:1M8D|interpro:IPR017938|rcsb pdb:1M8E|rcsb pdb:1M8H|rcsb pdb:1M8I|rcsb pdb:1M9T|rcsb pdb:1N2N|rcsb pdb:1NOC|rcsb pdb:1NOD|rcsb pdb:1NOS|rcsb pdb:1QOM|rcsb pdb:2NOS|rcsb pdb:2ORO|rcsb pdb:2ORP|rcsb pdb:2ORQ|rcsb pdb:2ORR|rcsb pdb:2ORS|rcsb pdb:2ORT|rcsb pdb:2Y37|rcsb pdb:3DWJ|rcsb pdb:3E65|rcsb pdb:3E67|rcsb pdb:3E68|rcsb pdb:3E6L|rcsb pdb:3E6N|rcsb pdb:3E6O|rcsb pdb:3E6T|rcsb pdb:3E7I|rcsb pdb:3E7M|rcsb pdb:3E7T|rcsb pdb:3EAI|rcsb pdb:3EBD|rcsb pdb:3EBF|rcsb pdb:1QW4|rcsb pdb:1QW5|rcsb pdb:3GOF|rcsb pdb:3NOD|rcsb pdb:3NQS|rcsb pdb:3NW2|rcsb pdb:4JS9|rcsb pdb:4UX6|reactome:R-MMU-1222556|rcsb pdb:1R35|reactome:R-MMU-392154|rcsb pdb:1VAF|reactome:R-MMU-9033241|rcsb pdb:2BHJ|rcsb pdb:2NOD|ensembl:ENSMUSG00000020826(gene)|ensembl:ENSMUST00000018610(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0003779"(actin binding)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0020037"(heme binding)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0032310"(prostaglandin secretion)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0006954"(inflammatory response)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034617"(tetrahydrobiopterin binding)|go:"GO:0034618"(arginine binding)|go:"GO:0035690"|go:"GO:0009617"(response to bacterium)|go:"GO:0009725"(response to hormone)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0010181"(FMN binding)|go:"GO:0050661"(NADP binding)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051712"(positive regulation of killing of cells of another organism)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|refseq:NP_035057.1|refseq:NP_001300850.1|refseq:NP_001300851.1|dip:DIP-31080N|mint:MINT-1528218(identity) - comment:mint|function:This enzyme is an effector of chloramphenicol resistance in bacteria|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:In the xray complex 1noc, P29477 is chain A and P00483 is chain B Resolution 2.600|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:+vnkYvUMn5P2TDaWRfm4N5+LmR0562 rogid:ZJ5M1BnSL0l2eW+3eGeZ6bVqUiA10090 intact-crc:483CE94CC62458D3|rigid:9oJd3PBABTPeXGu763czi8Dimpc false tag:?-?(MINT-1528226) tag:?-?(MINT-1528219) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)