#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00639	uniprotkb:P68133	intact:EBI-8545986|intact:MINT-1504668|uniprotkb:Q8MJ27|uniprotkb:A5PK44|ensembl:ENSBTAP00000026784	intact:EBI-367510|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSP00000355645|uniprotkb:Q5T8M9	psi-mi:dnas1_bovin(display_long)|uniprotkb:DNASE1(gene name)|psi-mi:DNASE1(display_short)|uniprotkb:DNL1(gene name synonym)|uniprotkb:Deoxyribonuclease I(gene name synonym)	psi-mi:acts_human(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Kabsch et al. (1990)	pubmed:2395459|mint:MINT-5220190	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8545980|mint:MINT-24966	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_010817356.1|refseq:NP_776959.1|refseq:XP_015315661.1|refseq:XP_015315662.1|refseq:XP_015315663.1|refseq:XP_015315660.1|dip:DIP-541N|ensembl:ENSBTAG00000020107(gene)|ensembl:ENSBTAT00000026784(transcript)|go:"GO:0000737"(DNA catabolic process, endonucleolytic)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0070948"(regulation of neutrophil mediated cytotoxicity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR016202(Deoxyribonuclease I-like)|interpro:IPR018057|interpro:IPR033125|interpro:IPR036691|rcsb pdb:1ATN|rcsb pdb:1DNK|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2D1K|rcsb pdb:2DNJ|rcsb pdb:3CJC|rcsb pdb:3DNI|rcsb pdb:3W3D|mint:MINT-1504684(identity)	ensembl:ENSG00000143632(gene)|ensembl:ENST00000366684(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043531"(ADP binding)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68133|reactome:R-HSA-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001091.1|mint:MINT-1504677(identity)	-	comment:mint|function:Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:In the xray complex 1atn, P02568 is chain A and P00639 is chain D Resolution 2.800|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/12	2014/10/16	rogid:19yE2D6HesESZJvLu4rp3cFxSSg9913	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49606	intact-crc:701A1B649B1E8760|rigid:qzV2mL+I8GN+cRdNIKKHTOEUtPo	false	tag:?-?(MINT-1504685)	tag:?-?(MINT-1504678)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)