#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P02976 uniprotkb:P02741 intact:EBI-7340383|intact:MINT-1206155|psi-mi:MINT-5231072|uniprotkb:Q2G1N8|ensemblbacteria:ABD29253 intact:EBI-1395983|uniprotkb:A8K078|uniprotkb:Q08AK3|uniprotkb:Q8WW75|uniprotkb:D3DVD9|uniprotkb:D3DVE0|ensembl:ENSP00000255030 psi-mi:spa_staa8(display_long)|uniprotkb:spa(gene name)|psi-mi:spa(display_short)|uniprotkb:SAOUHSC_00069(locus name)|uniprotkb:Staphylococcal protein A(gene name synonym) psi-mi:crp_human(display_long)|uniprotkb:CRP(gene name)|psi-mi:CRP(display_short)|uniprotkb:PTX1(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Das et al. (2004) pubmed:15474020|imex:IM-13907|mint:MINT-5217226 taxid:93061(staa8)|taxid:93061("Staphylococcus aureus (strain NCTC 8325)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7340408|mint:MINT-50620|imex:IM-13907-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4Y4Y|rcsb pdb:5U4Y|rcsb pdb:6K64|rcsb pdb:6K65|rcsb pdb:6K68|rcsb pdb:6K6A|rcsb pdb:6K6B|rcsb pdb:6K3M|rcsb pdb:1DEE|interpro:IPR018392|refseq:YP_498670.1|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6B9Y|rcsb pdb:6B9Z|refseq:WP_000728764.1|ensemblbacteria:ABD29253(transcript)|ensemblbacteria:SAOUHSC_00069(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0019864"(IgG binding)|rcsb pdb:6SOW|interpro:IPR003132(Protein A, Ig-binding)|interpro:IPR005038(Octapeptide repeat)|interpro:IPR005877(YSIRK Gram-positive signal peptide)|interpro:IPR009063(Immunoglobulin/albumin-binding)|rcsb pdb:4Y5Z|interpro:IPR036779|rcsb pdb:5U3D|rcsb pdb:5U5F|rcsb pdb:5U5M|rcsb pdb:5U6A|interpro:IPR019931|mint:MINT-1206199(identity) refseq:NP_000558.2|refseq:NP_001315986.1|refseq:NP_001315987.1|dip:DIP-39125N|ensembl:ENSG00000132693(gene)|ensembl:ENST00000255030(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008228"(opsonization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032945"(negative regulation of mononuclear cell proliferation)|go:"GO:0033265"(choline binding)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045087"(innate immune response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|mint:P02741|rcsb pdb:1B09|rcsb pdb:1CRV|rcsb pdb:1GNH|rcsb pdb:1LJ7|rcsb pdb:3L2Y|rcsb pdb:3PVN|rcsb pdb:3PVO|reactome:R-HSA-173623|mint:MINT-1206205(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:"SHORTLABEL: it's an ELISA"|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/12/02 2014/10/16 rogid:m02uruh6f2k4nBjFlfu+Eu1IcRs93061 rogid:R7vKMSGKD4ETbUKVGL9IiL8jzjE9606 intact-crc:8C2A215A3BD88CCC|rigid:l+v9jWXl4oC8RLrzIflkTuU2QtI false tag:?-?(MINT-1206200) - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)