#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P07437	uniprotkb:P33981	intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829	intact:EBI-1645856|uniprotkb:Q15272|uniprotkb:Q5TCS0|uniprotkb:Q9BW51|uniprotkb:Q9NTM0|uniprotkb:E1P543|uniprotkb:B2RDW2|uniprotkb:A8K8U5|ensembl:ENSP00000358813	psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name)	psi-mi:ttk_human(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)|uniprotkb:MPS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dou et al. (2004)	pubmed:15304323|imex:IM-14043|mint:MINT-5217142	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7284597|mint:MINT-50598|imex:IM-14043-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N|mint:MINT-1203842(identity)	refseq:NP_003309.2|refseq:XP_011534401.1|refseq:XP_011534402.1|refseq:NP_001160163.1|dip:DIP-40642N|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051304"(chromosome separation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903096"(protein localization to meiotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|rcsb pdb:2X9E|rcsb pdb:2ZMC|rcsb pdb:2ZMD|rcsb pdb:3CEK|rcsb pdb:3DBQ|rcsb pdb:3GFW|rcsb pdb:3H9F|rcsb pdb:3HMN|rcsb pdb:3HMO|rcsb pdb:3HMP|rcsb pdb:3VQU|rcsb pdb:3W1F|rcsb pdb:3WYX|rcsb pdb:3WYY|rcsb pdb:3WZK|rcsb pdb:4B94|rcsb pdb:4BHZ|rcsb pdb:4BI0|rcsb pdb:4BI1|rcsb pdb:4BI2|rcsb pdb:4C4E|rcsb pdb:4C4F|rcsb pdb:4C4G|rcsb pdb:4C4H|rcsb pdb:4C4I|rcsb pdb:4C4J|rcsb pdb:4CV8|rcsb pdb:4CV9|rcsb pdb:4CVA|rcsb pdb:4D2S|rcsb pdb:4H7X|rcsb pdb:4H7Y|rcsb pdb:4JS8|rcsb pdb:4JT3|rcsb pdb:4O6L|rcsb pdb:4ZEG|rcsb pdb:5AP0|rcsb pdb:5AP1|rcsb pdb:5AP2|rcsb pdb:5AP3|rcsb pdb:5AP4|rcsb pdb:5AP5|rcsb pdb:5AP6|rcsb pdb:5AP7|rcsb pdb:5EH0|rcsb pdb:5EHL|rcsb pdb:5EHO|rcsb pdb:5EHY|rcsb pdb:5EI2|rcsb pdb:5EI6|rcsb pdb:5EI8|rcsb pdb:5LJJ|rcsb pdb:5MRB|rcsb pdb:5N7V|rcsb pdb:5N84|rcsb pdb:5N87|rcsb pdb:5N93|rcsb pdb:5N9S|rcsb pdb:5NA0|rcsb pdb:5NAD|rcsb pdb:5NTT|rcsb pdb:5O91|rcsb pdb:6B4W|rcsb pdb:6GVJ|rcsb pdb:6H3K|rcsb pdb:6N6O|rcsb pdb:6TN9|rcsb pdb:6TNB|rcsb pdb:6TNC|rcsb pdb:6TND|rcsb pdb:7CHM|rcsb pdb:7CHN|rcsb pdb:7CHT|rcsb pdb:7CIL|rcsb pdb:7CJA|rcsb pdb:7CLH|rcsb pdb:3WZJ|mint:MINT-1203836(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2004/12/01	2014/10/16	rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606	rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606	intact-crc:DF923F9A0B6148CA|rigid:wQ3PUITt86r0B4yCWAC22cOLp0E	false	-	tag:?-?(MINT-1203837)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33981	uniprotkb:O95359	intact:EBI-1645856|uniprotkb:Q15272|uniprotkb:Q5TCS0|uniprotkb:Q9BW51|uniprotkb:Q9NTM0|uniprotkb:E1P543|uniprotkb:B2RDW2|uniprotkb:A8K8U5|ensembl:ENSP00000358813	intact:EBI-720382|uniprotkb:Q4VXL6|uniprotkb:Q4VXL7|uniprotkb:Q5U5T7|uniprotkb:Q86WG6|uniprotkb:Q86WG7|uniprotkb:Q4VXL0|uniprotkb:Q4VXL3|uniprotkb:Q8TCK9|uniprotkb:Q9BVQ1|uniprotkb:Q9NZ41|uniprotkb:Q9NZR5|intact:EBI-2558151|intact:EBI-28968297|ensembl:ENSP00000334280|ensembl:ENSP00000358001	psi-mi:ttk_human(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)|uniprotkb:MPS1(gene name synonym)	psi-mi:tacc2_human(display_long)|uniprotkb:Anti-Zuai-1(gene name synonym)|uniprotkb:TACC2(gene name)|psi-mi:TACC2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dou et al. (2004)	pubmed:15304323|imex:IM-14043|mint:MINT-5217142	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7284634|mint:MINT-50599|imex:IM-14043-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003309.2|refseq:XP_011534401.1|refseq:XP_011534402.1|refseq:NP_001160163.1|dip:DIP-40642N|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051304"(chromosome separation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903096"(protein localization to meiotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|rcsb pdb:2X9E|rcsb pdb:2ZMC|rcsb pdb:2ZMD|rcsb pdb:3CEK|rcsb pdb:3DBQ|rcsb pdb:3GFW|rcsb pdb:3H9F|rcsb pdb:3HMN|rcsb pdb:3HMO|rcsb pdb:3HMP|rcsb pdb:3VQU|rcsb pdb:3W1F|rcsb pdb:3WYX|rcsb pdb:3WYY|rcsb pdb:3WZK|rcsb pdb:4B94|rcsb pdb:4BHZ|rcsb pdb:4BI0|rcsb pdb:4BI1|rcsb pdb:4BI2|rcsb pdb:4C4E|rcsb pdb:4C4F|rcsb pdb:4C4G|rcsb pdb:4C4H|rcsb pdb:4C4I|rcsb pdb:4C4J|rcsb pdb:4CV8|rcsb pdb:4CV9|rcsb pdb:4CVA|rcsb pdb:4D2S|rcsb pdb:4H7X|rcsb pdb:4H7Y|rcsb pdb:4JS8|rcsb pdb:4JT3|rcsb pdb:4O6L|rcsb pdb:4ZEG|rcsb pdb:5AP0|rcsb pdb:5AP1|rcsb pdb:5AP2|rcsb pdb:5AP3|rcsb pdb:5AP4|rcsb pdb:5AP5|rcsb pdb:5AP6|rcsb pdb:5AP7|rcsb pdb:5EH0|rcsb pdb:5EHL|rcsb pdb:5EHO|rcsb pdb:5EHY|rcsb pdb:5EI2|rcsb pdb:5EI6|rcsb pdb:5EI8|rcsb pdb:5LJJ|rcsb pdb:5MRB|rcsb pdb:5N7V|rcsb pdb:5N84|rcsb pdb:5N87|rcsb pdb:5N93|rcsb pdb:5N9S|rcsb pdb:5NA0|rcsb pdb:5NAD|rcsb pdb:5NTT|rcsb pdb:5O91|rcsb pdb:6B4W|rcsb pdb:6GVJ|rcsb pdb:6H3K|rcsb pdb:6N6O|rcsb pdb:6TN9|rcsb pdb:6TNB|rcsb pdb:6TNC|rcsb pdb:6TND|rcsb pdb:7CHM|rcsb pdb:7CHN|rcsb pdb:7CHT|rcsb pdb:7CIL|rcsb pdb:7CJA|rcsb pdb:7CLH|rcsb pdb:3WZJ|mint:MINT-1203896(identity)	refseq:NP_001278807.1|refseq:NP_996744.3|refseq:NP_008928.1|refseq:NP_996742.1|refseq:NP_996743.1|ensembl:ENST00000260733|ensembl:ENSP00000260733|ensembl:ENSP00000334280|ensembl:ENST00000358010|ensembl:ENSP00000350701|ensembl:ENST00000360561|ensembl:ENSP00000353763|ensembl:ENST00000369000|ensembl:ENSP00000357996|ensembl:ENSP00000358001|ensembl:ENST00000513429|ensembl:ENSP00000425062|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021987"(cerebral cortex development)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O95359|go:"GO:0008283"(cell population proliferation)|ensembl:ENSG00000138162(gene)|ensembl:ENST00000334433(transcript)|ensembl:ENST00000369005(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007052"(mitotic spindle organization)|mint:MINT-1203902(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2004/12/01	2014/10/16	rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606	rogid:F497RHDDNDqTPKybxJ/DiuhfjAc9606	intact-crc:941E43E98A8F2AB0|rigid:Ac6BOOulBQvKrovDXysYOm3jOaw	false	tag:?-?(MINT-1203897)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:O95359	uniprotkb:P33981	intact:EBI-720382|uniprotkb:Q4VXL6|uniprotkb:Q4VXL7|uniprotkb:Q5U5T7|uniprotkb:Q86WG6|uniprotkb:Q86WG7|uniprotkb:Q4VXL0|uniprotkb:Q4VXL3|uniprotkb:Q8TCK9|uniprotkb:Q9BVQ1|uniprotkb:Q9NZ41|uniprotkb:Q9NZR5|intact:EBI-2558151|intact:EBI-28968297|ensembl:ENSP00000334280|ensembl:ENSP00000358001	intact:EBI-1645856|uniprotkb:Q15272|uniprotkb:Q5TCS0|uniprotkb:Q9BW51|uniprotkb:Q9NTM0|uniprotkb:E1P543|uniprotkb:B2RDW2|uniprotkb:A8K8U5|ensembl:ENSP00000358813	psi-mi:tacc2_human(display_long)|uniprotkb:Anti-Zuai-1(gene name synonym)|uniprotkb:TACC2(gene name)|psi-mi:TACC2(display_short)	psi-mi:ttk_human(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)|uniprotkb:MPS1(gene name synonym)	psi-mi:"MI:0428"(imaging technique)	Dou et al. (2004)	pubmed:15304323|imex:IM-14043|mint:MINT-5217142	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7284660|mint:MINT-50600|imex:IM-14043-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278807.1|refseq:NP_996744.3|refseq:NP_008928.1|refseq:NP_996742.1|refseq:NP_996743.1|ensembl:ENST00000260733|ensembl:ENSP00000260733|ensembl:ENSP00000334280|ensembl:ENST00000358010|ensembl:ENSP00000350701|ensembl:ENST00000360561|ensembl:ENSP00000353763|ensembl:ENST00000369000|ensembl:ENSP00000357996|ensembl:ENSP00000358001|ensembl:ENST00000513429|ensembl:ENSP00000425062|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021987"(cerebral cortex development)|interpro:IPR007707(Transforming acidic coiled-coil-containing)|interpro:IPR039915|mint:O95359|go:"GO:0008283"(cell population proliferation)|ensembl:ENSG00000138162(gene)|ensembl:ENST00000334433(transcript)|ensembl:ENST00000369005(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007052"(mitotic spindle organization)|mint:MINT-1203885(identity)	refseq:NP_003309.2|refseq:XP_011534401.1|refseq:XP_011534402.1|refseq:NP_001160163.1|dip:DIP-40642N|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051304"(chromosome separation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903096"(protein localization to meiotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|rcsb pdb:2X9E|rcsb pdb:2ZMC|rcsb pdb:2ZMD|rcsb pdb:3CEK|rcsb pdb:3DBQ|rcsb pdb:3GFW|rcsb pdb:3H9F|rcsb pdb:3HMN|rcsb pdb:3HMO|rcsb pdb:3HMP|rcsb pdb:3VQU|rcsb pdb:3W1F|rcsb pdb:3WYX|rcsb pdb:3WYY|rcsb pdb:3WZK|rcsb pdb:4B94|rcsb pdb:4BHZ|rcsb pdb:4BI0|rcsb pdb:4BI1|rcsb pdb:4BI2|rcsb pdb:4C4E|rcsb pdb:4C4F|rcsb pdb:4C4G|rcsb pdb:4C4H|rcsb pdb:4C4I|rcsb pdb:4C4J|rcsb pdb:4CV8|rcsb pdb:4CV9|rcsb pdb:4CVA|rcsb pdb:4D2S|rcsb pdb:4H7X|rcsb pdb:4H7Y|rcsb pdb:4JS8|rcsb pdb:4JT3|rcsb pdb:4O6L|rcsb pdb:4ZEG|rcsb pdb:5AP0|rcsb pdb:5AP1|rcsb pdb:5AP2|rcsb pdb:5AP3|rcsb pdb:5AP4|rcsb pdb:5AP5|rcsb pdb:5AP6|rcsb pdb:5AP7|rcsb pdb:5EH0|rcsb pdb:5EHL|rcsb pdb:5EHO|rcsb pdb:5EHY|rcsb pdb:5EI2|rcsb pdb:5EI6|rcsb pdb:5EI8|rcsb pdb:5LJJ|rcsb pdb:5MRB|rcsb pdb:5N7V|rcsb pdb:5N84|rcsb pdb:5N87|rcsb pdb:5N93|rcsb pdb:5N9S|rcsb pdb:5NA0|rcsb pdb:5NAD|rcsb pdb:5NTT|rcsb pdb:5O91|rcsb pdb:6B4W|rcsb pdb:6GVJ|rcsb pdb:6H3K|rcsb pdb:6N6O|rcsb pdb:6TN9|rcsb pdb:6TNB|rcsb pdb:6TNC|rcsb pdb:6TND|rcsb pdb:7CHM|rcsb pdb:7CHN|rcsb pdb:7CHT|rcsb pdb:7CIL|rcsb pdb:7CJA|rcsb pdb:7CLH|rcsb pdb:3WZJ|mint:MINT-1203880(identity)	go:"GO:0005813"(centrosome)	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:Centrosomal localization of TACC2 is dependent on TKK kinase activity|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2004/12/01	2014/10/16	rogid:F497RHDDNDqTPKybxJ/DiuhfjAc9606	rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606	intact-crc:91F14884B8820491|rigid:Ac6BOOulBQvKrovDXysYOm3jOaw	false	-	-	-	-	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)