#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P25025 uniprotkb:P25025 intact:EBI-2835281|uniprotkb:Q8IUZ1|uniprotkb:Q9P2T7|uniprotkb:Q9P2T6|ensembl:ENSP00000319635 intact:EBI-2835281|uniprotkb:Q8IUZ1|uniprotkb:Q9P2T7|uniprotkb:Q9P2T6|ensembl:ENSP00000319635 psi-mi:cxcr2_human(display_long)|uniprotkb:CXCR2(gene name)|psi-mi:CXCR2(display_short)|uniprotkb:IL8RB(gene name synonym)|uniprotkb:CDw128b(gene name synonym)|uniprotkb:GRO/MGSA receptor(gene name synonym)|uniprotkb:High affinity interleukin-8 receptor B(gene name synonym)|uniprotkb:IL-8 receptor type 2(gene name synonym) psi-mi:cxcr2_human(display_long)|uniprotkb:CXCR2(gene name)|psi-mi:CXCR2(display_short)|uniprotkb:IL8RB(gene name synonym)|uniprotkb:CDw128b(gene name synonym)|uniprotkb:GRO/MGSA receptor(gene name synonym)|uniprotkb:High affinity interleukin-8 receptor B(gene name synonym)|uniprotkb:IL-8 receptor type 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Trettel et al. (2003) pubmed:12888558|mint:MINT-5216577 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6980764|mint:MINT-49809 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000180871(gene)|ensembl:ENST00000318507(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004918"(interleukin-8 receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|refseq:NP_001161770.1|refseq:NP_001548.1|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0031623"(receptor internalization)|go:"GO:0033030"(negative regulation of neutrophil apoptotic process)|go:"GO:0038112"(interleukin-8-mediated signaling pathway)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042629"(mast cell granule)|go:"GO:0043117"(positive regulation of vascular permeability)|refseq:XP_005246587.1|go:"GO:0060326"(cell chemotaxis)|go:"GO:0072173"(metanephric tubule morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|interpro:IPR000057(Interleukin 8B receptor)|interpro:IPR000174(Interleukin-8 receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|go:"GO:0045766"(positive regulation of angiogenesis)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4Q3H|rcsb pdb:5TYT|rcsb pdb:6KVA|rcsb pdb:6KVF|rcsb pdb:6LFM|rcsb pdb:6LFO|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6798695|refseq:XP_016859479.1|refseq:XP_016859480.1|refseq:XP_016859481.1|dip:DIP-3782N|mint:MINT-737622(identity) ensembl:ENSG00000180871(gene)|ensembl:ENST00000318507(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004918"(interleukin-8 receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|refseq:NP_001161770.1|refseq:NP_001548.1|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0031623"(receptor internalization)|go:"GO:0033030"(negative regulation of neutrophil apoptotic process)|go:"GO:0038112"(interleukin-8-mediated signaling pathway)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042629"(mast cell granule)|go:"GO:0043117"(positive regulation of vascular permeability)|refseq:XP_005246587.1|go:"GO:0060326"(cell chemotaxis)|go:"GO:0072173"(metanephric tubule morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|interpro:IPR000057(Interleukin 8B receptor)|interpro:IPR000174(Interleukin-8 receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|go:"GO:0045766"(positive regulation of angiogenesis)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4Q3H|rcsb pdb:5TYT|rcsb pdb:6KVA|rcsb pdb:6KVF|rcsb pdb:6LFM|rcsb pdb:6LFO|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6798695|refseq:XP_016859479.1|refseq:XP_016859480.1|refseq:XP_016859481.1|dip:DIP-3782N|mint:MINT-737614(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2004/05/23 2014/10/16 rogid:T16V0LpaqMIhUJlknnqmSVxX39o9606 rogid:T16V0LpaqMIhUJlknnqmSVxX39o9606 intact-crc:6FD73D2D77055B38|rigid:/XrNCVP0yGh+6DU6aV1umOQ/msU false binding-associated region:1-163(MINT-737623)|tag:?-?(MINT-737625) binding-associated region:1-163(MINT-737615)|tag:?-?(MINT-737617) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P42261 uniprotkb:P25025 intact:EBI-6980805|ensembl:ENSP00000285900|uniprotkb:B7Z3F6|uniprotkb:E7ESV8|intact:MINT-271172|uniprotkb:Q2NKM6|uniprotkb:D3DQI4|uniprotkb:B7Z2W8|uniprotkb:B7Z2S0|uniprotkb:B7Z9G9 intact:EBI-2835281|uniprotkb:Q8IUZ1|uniprotkb:Q9P2T7|uniprotkb:Q9P2T6|ensembl:ENSP00000319635 psi-mi:gria1_human(display_long)|uniprotkb:GRIA1(gene name)|psi-mi:GRIA1(display_short)|uniprotkb:GLUH1(gene name synonym)|uniprotkb:GLUR1(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 1(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 1(gene name synonym)|uniprotkb:GluR-A(gene name synonym)|uniprotkb:GluR-K1(gene name synonym) psi-mi:cxcr2_human(display_long)|uniprotkb:CXCR2(gene name)|psi-mi:CXCR2(display_short)|uniprotkb:IL8RB(gene name synonym)|uniprotkb:CDw128b(gene name synonym)|uniprotkb:GRO/MGSA receptor(gene name synonym)|uniprotkb:High affinity interleukin-8 receptor B(gene name synonym)|uniprotkb:IL-8 receptor type 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Trettel et al. (2003) pubmed:12888558|mint:MINT-5216577 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6980801|mint:MINT-49811 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:6X5Q|reactome:R-HSA-204005|reactome:R-HSA-399710|reactome:R-HSA-399719|reactome:R-HSA-416993|reactome:R-HSA-438066|reactome:R-HSA-5694530|reactome:R-HSA-8849932|reactome:R-HSA-9620244|ensembl:ENSG00000155511(gene)|ensembl:ENST00000285900(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007616"(long-term memory)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|refseq:NP_000818.2|refseq:NP_001244952.1|refseq:NP_001244948.1|refseq:NP_001244950.1|refseq:NP_001244951.1|refseq:NP_001107655.1|dip:DIP-41487N|mint:MINT-737592(identity) ensembl:ENSG00000180871(gene)|ensembl:ENST00000318507(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004918"(interleukin-8 receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|refseq:NP_001161770.1|refseq:NP_001548.1|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0031623"(receptor internalization)|go:"GO:0033030"(negative regulation of neutrophil apoptotic process)|go:"GO:0038112"(interleukin-8-mediated signaling pathway)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042629"(mast cell granule)|go:"GO:0043117"(positive regulation of vascular permeability)|refseq:XP_005246587.1|go:"GO:0060326"(cell chemotaxis)|go:"GO:0072173"(metanephric tubule morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|interpro:IPR000057(Interleukin 8B receptor)|interpro:IPR000174(Interleukin-8 receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|go:"GO:0045766"(positive regulation of angiogenesis)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4Q3H|rcsb pdb:5TYT|rcsb pdb:6KVA|rcsb pdb:6KVF|rcsb pdb:6LFM|rcsb pdb:6LFO|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6798695|refseq:XP_016859479.1|refseq:XP_016859480.1|refseq:XP_016859481.1|dip:DIP-3782N|mint:MINT-737584(identity) - comment:mint|function:Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2004/05/23 2014/10/16 rogid:0EPt2spHxfw0aT7tYfD1+LoLHK09606 rogid:T16V0LpaqMIhUJlknnqmSVxX39o9606 intact-crc:44CA47227118697C|rigid:7kNZD9QM3OWP6bk2v3bMjV90w9s false tag:?-?(MINT-737593) binding-associated region:1-142(MINT-737585)|tag:?-?(MINT-737587) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P35407 uniprotkb:P35407 intact:EBI-937591|ensembl:ENSRNOP00000019109 intact:EBI-937591|ensembl:ENSRNOP00000019109 psi-mi:cxcr2_rat(display_long)|uniprotkb:Cxcr2(gene name)|psi-mi:Cxcr2(display_short)|uniprotkb:Il8rb(gene name synonym)|uniprotkb:High affinity interleukin-8 receptor B(gene name synonym)|uniprotkb:GRO/MGSA receptor(gene name synonym) psi-mi:cxcr2_rat(display_long)|uniprotkb:Cxcr2(gene name)|psi-mi:Cxcr2(display_short)|uniprotkb:Il8rb(gene name synonym)|uniprotkb:High affinity interleukin-8 receptor B(gene name synonym)|uniprotkb:GRO/MGSA receptor(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Trettel et al. (2003) pubmed:12888558|mint:MINT-5216577 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6980876|mint:MINT-49810 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_008765435.1|rgd:2906|refseq:NP_058879.1|ensembl:ENSRNOG00000014269(gene)|ensembl:ENSRNOT00000019109(transcript)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0002690"(positive regulation of leukocyte chemotaxis)|go:"GO:0004918"(interleukin-8 receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006935"(chemotaxis)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030901"(midbrain development)|go:"GO:0031623"(receptor internalization)|go:"GO:0033030"(negative regulation of neutrophil apoptotic process)|go:"GO:0038112"(interleukin-8-mediated signaling pathway)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042629"(mast cell granule)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043117"(positive regulation of vascular permeability)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0072173"(metanephric tubule morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|interpro:IPR000057(Interleukin 8B receptor)|interpro:IPR000174(Interleukin-8 receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-380108|reactome:R-RNO-418594|reactome:R-RNO-6798695|mint:MINT-737602(identity) refseq:XP_008765435.1|rgd:2906|refseq:NP_058879.1|ensembl:ENSRNOG00000014269(gene)|ensembl:ENSRNOT00000019109(transcript)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0002690"(positive regulation of leukocyte chemotaxis)|go:"GO:0004918"(interleukin-8 receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006935"(chemotaxis)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030901"(midbrain development)|go:"GO:0031623"(receptor internalization)|go:"GO:0033030"(negative regulation of neutrophil apoptotic process)|go:"GO:0038112"(interleukin-8-mediated signaling pathway)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042629"(mast cell granule)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043117"(positive regulation of vascular permeability)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0072173"(metanephric tubule morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|interpro:IPR000057(Interleukin 8B receptor)|interpro:IPR000174(Interleukin-8 receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-380108|reactome:R-RNO-418594|reactome:R-RNO-6798695|mint:MINT-737607(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2004/05/23 2014/10/16 rogid:Wbxk56bXvCJF4Lisy+JUFBoakrw10116 rogid:Wbxk56bXvCJF4Lisy+JUFBoakrw10116 intact-crc:23FBD3F881F883E4|rigid:f7oDDOzO2PcG3U3vmRB2Ccec/GY false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)