#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O35740 uniprotkb:Q09472 intact:EBI-8654672|uniprotkb:O35743|uniprotkb:O55198|intact:MINT-365410|uniprotkb:Q6PGA9|uniprotkb:O35741|uniprotkb:O35742|ensembl:ENSMUSP00000038405|ensembl:ENSMUSP00000151452 intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|intact:EBI-28987257|ensembl:ENSP00000263253 psi-mi:cite2_mouse(display_long)|uniprotkb:Cited2(gene name)|psi-mi:Cited2(display_short)|uniprotkb:Mrg1(gene name synonym)|uniprotkb:Msg2(gene name synonym)|uniprotkb:MSG-related protein 1(gene name synonym)|uniprotkb:P35srj(gene name synonym) psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Freedman et al. (2003) pubmed:12778114|mint:MINT-5216417 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8654754|mint:MINT-24817 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034958.2|ensembl:ENSMUSG00000039910(gene)|ensembl:ENSMUST00000038107(transcript)|ensembl:ENSMUST00000219558(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001944"(vasculature development)|go:"GO:0001947"(heart looping)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002521"(leukocyte differentiation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003156"(regulation of animal organ formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007530"(sex determination)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021602"(cranial nerve morphogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035802"(adrenal cortex formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0001841"(neural tube formation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:1900164"(nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|go:"GO:2000020"(positive regulation of male gonad development)|go:"GO:0046697"(decidualization)|interpro:IPR007576(CITED)|reactome:R-MMU-1234158|reactome:R-MMU-8866907|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050693"(LBD domain binding)|mint:MINT-365446(identity) refseq:NP_001420.2|ensembl:ENSP00000263253|dip:DIP-257N|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|go:"GO:0140067"(peptidyl-lysine butyrylation)|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9707616|rcsb pdb:4BHW|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENSG00000100393(gene)|ensembl:ENST00000263253(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006473"(protein acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0006915"(apoptotic process)|go:"GO:0036268"(swimming)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|mint:MINT-365453(identity) - function:Interferes with the binding of transcription factors HIF-1a and STAT2 to p300/CBP|comment:mint - figure legend:3|kinetics:IC50 3.7 nanomolar|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:05fyJh/1DkYmhJ6x570oPce2C8010090 rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606 intact-crc:37C463F127B19443|rigid:C3ow8C1J90FPksgG01/Y3YvCf8c false binding-associated region:216-259(MINT-4444726) binding-associated region:323-423(MINT-4445499) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)