#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P04050	uniprotkb:P38827	intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C	intact:EBI-16977|uniprotkb:D3DL69|ensemblfungi:YHR119W	psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym)	psi-mi:set1_yeast(display_long)|uniprotkb:SET1(gene name)|psi-mi:SET1(display_short)|uniprotkb:YTX1(gene name synonym)|uniprotkb:KMT2(gene name synonym)|uniprotkb:COMPASS component SET1(gene name synonym)|uniprotkb:SET domain-containing protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2(gene name synonym)|uniprotkb:YHR119W(locus name)	psi-mi:"MI:0045"(experimental interaction detection)	Ng et al. (2003)	pubmed:12667453|mint:MINT-5216296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8629754|mint:MINT-50763	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-732089(identity)	ensemblfungi:YHR119W(gene)|ensemblfungi:YHR119W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0006348"|go:"GO:0006479"(protein methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1903341"(regulation of meiotic DNA double-strand break formation)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017111(Histone H3-K4 methyltransferase Set1)|interpro:IPR024636|interpro:IPR024657|interpro:IPR044570|rcsb pdb:2J8A|rcsb pdb:6VEN|reactome:R-SCE-3214841|refseq:NP_011987.1|sgd:S000001161|dip:DIP-4616N|mint:P38827|mint:MINT-732083(identity)	-	crc64:A45C1360FF99F968|comment:"Stoichiometry: 1.0"	crc64:B7FA5D60F71063FD|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F3B|comment:homomint|comment:mint|negative:true	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2004/12/13	2014/10/16	rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292	rogid:QviRdWKz1+2O63RmD9p2MeyA9Jg559292	intact-crc:F7D0465CBF2D1A34|rigid:nmmqwculhs0Zg7uig5TaUnnMZ2I	true	O-phospho-L-serine:2-2(MINT-732090)	tag:?-?(MINT-732084)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P38827	uniprotkb:P32585	intact:EBI-16977|uniprotkb:D3DL69|ensemblfungi:YHR119W	intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C	psi-mi:set1_yeast(display_long)|uniprotkb:SET1(gene name)|psi-mi:SET1(display_short)|uniprotkb:YTX1(gene name synonym)|uniprotkb:KMT2(gene name synonym)|uniprotkb:COMPASS component SET1(gene name synonym)|uniprotkb:SET domain-containing protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2(gene name synonym)|uniprotkb:YHR119W(locus name)	psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym)	psi-mi:"MI:0045"(experimental interaction detection)	Ng et al. (2003)	pubmed:12667453|mint:MINT-5216296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8629773|mint:MINT-50764	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR119W(gene)|ensemblfungi:YHR119W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0006348"|go:"GO:0006479"(protein methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1903341"(regulation of meiotic DNA double-strand break formation)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017111(Histone H3-K4 methyltransferase Set1)|interpro:IPR024636|interpro:IPR024657|interpro:IPR044570|rcsb pdb:2J8A|rcsb pdb:6VEN|reactome:R-SCE-3214841|refseq:NP_011987.1|sgd:S000001161|dip:DIP-4616N|mint:P38827|mint:MINT-732069(identity)	sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585|mint:MINT-732075(identity)	-	crc64:B7FA5D60F71063FD|comment:"Stoichiometry: 1.0"	crc64:B1148FC187C2802A|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|figure legend:F3B|comment:mint|negative:true	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2004/12/13	2014/10/16	rogid:QviRdWKz1+2O63RmD9p2MeyA9Jg559292	rogid:+/qC0affGDlvusbTV43B3aCgZBU559292	intact-crc:6D5BC70A5EC23AD8|rigid:6W/rQ6YsZNnu2fY1esplNPq3Xak	true	tag:?-?(MINT-732070)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)